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Darrin Jason Lee, MD, PhD

Associate Professor of Neurological Surgery, Psychiatry and the Behavioral Sciences and Biomedical Engineering (Clinical Scholar)

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Email darrinjl@usc.edu
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Awards

  • Howard Hughes Medical Institute: Howard Hughes Medical Institute Fellow, 2007
     – 2008
  • American Association of Neurological Surgeons: William P. Van Wagenen Fellow, 2017
     – 2018
  • American Academy of Neurological Surgeons: Emerging Investigator Scholar, 2019
     – 2020
  • American Geriatrics Society: Clinician Specialists Rising Star, 2021
  • Brian and Behavior Research Foundation: Brain and Behavior Research Foundation Young Investigator, 2022

Education and Training

  • Brown University — B.S. — 06/2002 — Neuroscience and Philosophy
  • University of California Irvine — MD — 06/2009 — Medicine
  • University of California Davis — PhD — 12/2013 — Neuroscience
  • University of California Davis — 06/2017 — Neurosurgery Residency
  • University of Toronto — 06/2018 — Stereotactic and Functional Neurosurgery Fellowship

Research Funding

  • Theta burst subthalamic nucleus deep brain stimulation for cognitive and motor improvements in Parkinson's Disease
    NIH · UG3NS132960 · Sep 18, 2024 – Aug 31, 2029 · Role: Principal Investigator
  • Theta Burst Subthalamic Nucleus Deep Brain Stimulation for Cognitive and Motor Improvements in Parkinson's Disease
    NIH · UH3NS132960 · Sep 1, 2024 – Aug 31, 2029 · Role: Principal Investigator
  • Septohippocampal circuit deep brain stimulation for selective RDoC aspects of cognition
    NIH · K08MH121757 · Jun 1, 2020 – May 31, 2025 · Role: Principal Investigator

Publications

  • Chronic subthreshold rTMS transiently disrupts learning but enhances memory and flexibility in healthy rats. J Neural Eng. 2026 Sep 25; 23(5).. View in PubMed
  • Coccidioides meningitis as a cause of low-pressure hydrocephalus: A contemporary case series and management strategy. Clin Neurol Neurosurg. 2026 Oct; 269:109559.. View in PubMed
  • Neuromodulatory strategies overcome multiple inevitable impairments of cerebral palsy. J Neurophysiol. 2026 Aug 01; 136(2):445-458.. View in PubMed
  • Real-time brain-computer interface control of walking exoskeleton with bilateral sensory feedback. Brain Stimul. 2026 May-Jun; 19(3):103065.. View in PubMed
  • Cerebral Perfusion and Blood-Brain Barrier Changes After Cranioplasty: A Diffusion-Prepared Arterial Spin Labeling Study. J Neuroimaging. 2025 Nov-Dec; 35(6):e70106.. View in PubMed
  • Visual Neurorestoration: An Expert Review of Current Strategies for Restoring Vision in Humans. Brain Sci. 2025 Oct 30; 15(11).. View in PubMed
  • Functional ultrasound imaging combined with machine learning for whole-brain analysis of drug-induced hemodynamic changes. Imaging Neurosci (Camb). 2025; 3.. View in PubMed
  • Human spinal cord activation during filling and emptying of the bladder. Nat Commun. 2025 Jul 15; 16(1):6506.. View in PubMed
  • Comparative evaluation of image registration techniques in functional ultrasound imaging. Imaging Neurosci (Camb). 2025; 3.. View in PubMed
  • Electromagnetic stimulation for amblyopia: A systematic review of emerging techniques and their efficacy. Vision Res. 2025 Sep; 234:108639.. View in PubMed

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