David I Quinn, MD

Clinical Professor of Medicine

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Overview

David Ian Quinn MBBS Honors Class I, PhD, FRACP FACP is an international expert in the field of clinical trials and molecular correlative studies in genitourinary cancer. Dr. Quinn is the medical director of the Norris Cancer Hospital and Clinics, head of the Section of Genitourinary Medical Oncology and associate professor of Medicine in the Division of Cancer Medicine and Blood Diseases at the Keck School of Medicine of USC. Prior experience includes Directorship of the Clinical Investigation Support Office and Leadership of the Genitourinary Cancer and Developmental Therapeutics Programs for the USC Norris Comprehensive Cancer Center.

He is a medical oncologist with focus in the field of clinical trials and molecular correlative studies in genitourinary cancer and early therapeutics. David Quinn has published more than 200 papers, reviews and chapters including recent publications in the journals Cancer Research, Clinical Cancer Research, Oncogene, Proceedings of the National Academy of Science, Journal of the National Cancer Institute, Lancet, Lancet Oncology, New England Journal of Medicine and Journal of Clinical Oncology. Dr. Quinn is a reviewer for more than 50 peer-reviewed journals and is on the editorial boards of is on the editorial boards of American Journal of Clinical Oncology, cancer.net (American Society of Clinical Oncology), Clinical Genitourinary Cancer, Bladder Cancer and Annals of Oncology. Dr. Quinn is a member of the NCI Prostate Cancer Task Force, Co-Chair for Genitourinary Cancer in the California Cancer Consortium and is SWOG organ site chair for advanced prostate cancer. He is a full member of the Department of Defense Integration Panel for Prostate Cancer Awards and has been an invited speaker in more than 40 countries.

Dr. Quinn’s current focus is on clinical trials and translation applications at USC and with SWOG and the California Cancer Consortium, where he has been principal investigator on more than 100 clinical trials for locally advanced and castrate-resistant prostate cancer, high grade urothelial cancer, advanced renal cell cancer, refractory germ cell tumors and adrenocortical carcinoma.

Awards

  • Castle Connolly Medical: America’s Top Doctors, 2010
  • USC Norris Cancer Center and Hospital: The Spirit of Norris Award, 2002
  • Royal Australasian College of Physicians: Vincent Fairfax Family Fellowship, 2001
  • National Health and Medical Research Council of Australia: Neil Hamilton Fairley Fellowship, 2000-2003
  • St. Vincent’s Clinic Foundation: The David Wilson Travelling Fellowship, 2000
  • Postgraduate Medical Council of New South Wales: Distinguished Contribution Award, 2000
  • National Health and Medical Research Council of Australia: Postgraduate Medical Scholarship, 1996-1999
  • University of New South Wales: Gordon Lowe Memorial Prize, 1987
  • University of New South Wales: Honours First Class Bachelor of Medicine, Bachelor of Surgery, 1987

Publications

  • Access to high-volume surgeons and the opportunity cost of performing radical prostatectomy by low-volume providersUrol Oncol. 2017 07; 35(7):459. e15-459. e24. . View in PubMed
  • Albumin levels predict prognosis in advanced renal cell carcinoma treated with tyrosine kinase inhibitors: a systematic review and meta-analysisUrol Oncol. 2022 01; 40(1):12. e13-12. e22. . View in PubMed
  • Circulating Tumor Cell Count and Overall Survival in Patients With Metastatic Hormone-Sensitive Prostate Cancer JAMA Netw Open. 2024 Oct 01; 7(10):e2437871. . View in PubMed
  • Three- and Seven-month Prostate-specific Antigen Levels as Prognostic Markers for Overall Survival in Metastatic Hormone-sensitive Prostate Cancer: Results from SWOG S1216, a Phase 3 Randomized Trial of Androgen Deprivation Plus Orteronel or Bicalutamide Eur Urol Oncol. 2024 Oct; 7(5):1097-1104. . View in PubMed
  • Development of a quality of life measure for left ventricular assist device recipients using a mixed methods approach ESC Heart Fail. 2024 Oct; 11(5):3167-3179. . View in PubMed
  • Final Results From a Phase I Trial and Expansion Cohorts of Cabozantinib and Nivolumab Alone or With Ipilimumab for Advanced/Metastatic Genitourinary Tumors J Clin Oncol. 2024 Sep 01; 42(25):3033-3046. . View in PubMed
  • Markers of bone metabolism and overall survival in men with bone-metastatic hormone sensitive prostate cancer (HSPC): A subset analysis of SWOG S1216, a phase III trial of androgen deprivation with or without orteronel Prostate Cancer Prostatic Dis. 2024 Sep; 27(3):566-570. . View in PubMed
  • Impact of Prior Chemotherapy on Response to Second-line Pembrolizumab in Urothelial Cancer: Exploratory Analysis of the Phase 3 KEYNOTE-045 Trial Eur Urol. 2024 Aug 21. . View in PubMed
  • Clinical and cost-effectiveness of left ventricular assist devices as destination therapy for advanced heart failure: systematic review and economic evaluation Health Technol Assess. 2024 Aug; 28(38):1-237. . View in PubMed
  • Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Oncotarget. 2024 Jul 10; 15:444-458. . View in PubMed
  • The Complementary Roles of Open and Endovascular Repair of Extent I – III Thoraco-abdominal Aortic Aneurysms in a United Kingdom Aortic Centre Eur J Vasc Endovasc Surg. 2024 Jul; 68(1):62-72. . View in PubMed
  • Bone Biomarkers and Subsequent Survival in Men with Hormone-sensitive Prostate Cancer: Results from the SWOG S1216 Phase 3 Trial of Androgen Deprivation Therapy with or Without Orteronel Eur Urol. 2024 Feb; 85(2):171-176. . View in PubMed
  • Impact of Prior Cytoreductive Nephrectomy on Efficacy in Patients with Synchronous Metastatic Renal Cell Carcinoma Treated with Avelumab plus Axitinib or Sunitinib: Post Hoc Analysis from the JAVELIN Renal 101 Phase 3 Trial Eur Urol. 2024 01; 85(1):8-12. . View in PubMed
  • Ibrutinib combination therapy for advanced gastrointestinal and genitourinary tumours: results from a phase 1b/2 study BMC Cancer. 2023 Nov 03; 23(1):1056. . View in PubMed
  • EphrinB2: Expression of a novel potential target in renal cell carcinoma Indian J Urol. 2023 Jul-Sep; 39(3):223-227. . View in PubMed
  • Cell-free DNA Methylation as a Predictive Biomarker of Response to Neoadjuvant Chemotherapy for Patients with Muscle-invasive Bladder Cancer in SWOG S1314 Eur Urol Oncol. 2023 10; 6(5):516-524. . View in PubMed
  • Combination Treatment with Sipuleucel-T and Abiraterone Acetate or Enzalutamide for Metastatic Castration-Resistant Prostate Cancer: STAMP and STRIDE Trials Clin Cancer Res. 2023 07 05; 29(13):2426-2434. . View in PubMed
  • SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer Cancer Res. 2023 11 15; 83(22):3813-3826. . View in PubMed
  • Race and Treatment Outcomes in Patients With Metastatic Castration-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG 1216 Phase 3 Trial JAMA Netw Open. 2023 08 01; 6(8):e2326546. . View in PubMed
  • Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study Oncology. 2023; 101(6):375-388. . View in PubMed
  • A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy Clin Cancer Res. 2023 06 01; 29(11):2052-2065. . View in PubMed
  • Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers Nat Commun. 2023 02 06; 14(1):630. . View in PubMed
  • EphrinB2 Inhibition and Pembrolizumab in Metastatic Urothelial Carcinoma J Clin Oncol. 2023 01 20; 41(3):640-650. . View in PubMed
  • FORT-1: Phase II/III Study of Rogaratinib Versus Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Selected Based on FGFR1/3 mRNA Expression J Clin Oncol. 2023 01 20; 41(3):629-639. . View in PubMed
  • Outcomes of temporary mechanical circulatory support in cardiogenic shock due to end-stage heart failure J Intensive Care Soc. 2022 May; 23(2):170-176. . View in PubMed
  • Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis Int J Mol Sci. 2022 Feb 25; 23(5). . View in PubMed
  • Management Trends and Outcomes of Patients Undergoing Radical Cystectomy for Urothelial Carcinoma of the Bladder: Evolution of the University of Southern California Experience over 3,347 Cases J Urol. 2022 Feb; 207(2):302-313. . View in PubMed
  • Thoracic aortic aneurysm repair using the elephant trunk technique and associated complications Clin Radiol. 2022 11; 77(11):803-809. . View in PubMed
  • Oligometastatic Prostate Cancer: Current Status and Future Challenges J Nucl Med. 2022 11; 63(11):1628-1635. . View in PubMed
  • A Phase II, Single-arm Trial of Sunitinib and Erlotinib in Advanced Renal Cell Carcinoma Clin Genitourin Cancer. 2022 10; 20(5):415-422. . View in PubMed
  • Integration of Liquid Biopsies in Clinical Management of Metastatic Prostate Cancer Curr Oncol Rep. 2022 10; 24(10):1287-1298. . View in PubMed
  • Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial Lancet Oncol. 2022 09; 23(9):1133-1144. . View in PubMed
  • Health-related Quality of Life of Patients with Locally Advanced or Metastatic Urothelial Cancer Treated with Enfortumab Vedotin after Platinum and PD-1/PD-L1 Inhibitor Therapy: Results from Cohort 1 of the Phase 2 EV-201 Clinical Trial Eur Urol. 2022 05; 81(5):515-522. . View in PubMed
  • Assessing hypoxic damage to placental trophoblasts by measuring membrane viscosity of extracellular vesicles Placenta. 2022 04; 121:14-22. . View in PubMed
  • Bladder cancer: from a therapeutic wilderness to so many options; a guide to practice in a changing landscape Ann Oncol. 2022 03; 33(3):242-243. . View in PubMed
  • Infigratinib in Early-Line and Salvage Therapy for FGFR3-Altered Metastatic Urothelial Carcinoma Clin Genitourin Cancer. 2022 02; 20(1):35-42. . View in PubMed
  • Reply by Authors J Urol. 2022 02; 207(2):313. . View in PubMed
  • Feasibility of using CT radiomic signatures for predicting CD8-T cell infiltration and PD-L1 expression in renal cell carcinoma Eur J Radiol Open. 2022; 9:100440. . View in PubMed
  • Putative Biomarkers of Clinical Benefit With Pembrolizumab in Advanced Urothelial Cancer: Results from the KEYNOTE-045 and KEYNOTE-052 Landmark Trials Clin Cancer Res. 2022 05 13; 28(10):2050-2060. . View in PubMed
  • Orteronel for Metastatic Hormone-Sensitive Prostate Cancer: A Multicenter, Randomized, Open-Label Phase III Trial (SWOG-1216) J Clin Oncol. 2022 10 01; 40(28):3301-3309. . View in PubMed
  • Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer Nat Commun. 2022 11 04; 13(1):6658. . View in PubMed
  • Living with a left ventricular assist device: Capturing recipients experiences using group concept mapping software PLoS One. 2022; 17(9):e0273108. . View in PubMed
  • Open surgical replacement of the descending thoracic and thoracoabdominal aorta in patients with confirmed Marfan and Loeys-Dietz syndromes: A 20-year single-centre experience Eur J Cardiothorac Surg. 2022 08 03; 62(3). . View in PubMed
  • Cardiac Power Output Index and Severe Primary Graft Dysfunction After Heart Transplantation J Cardiothorac Vasc Anesth. 2021 Feb; 35(2):398-403. . View in PubMed
  • Phase II trial of brentuximab vedotin in relapsed/refractory germ cell tumors Invest New Drugs. 2021 12; 39(6):1656-1663. . View in PubMed
  • Pathophysiology of severe primary graft dysfunction in orthotopic heart transplantation Clin Transplant. 2021 09; 35(9):e14398. . View in PubMed
  • ATLAS trial of adjuvant axitinib in patients with renal cell carcinoma: subgroup analyses with focus on axitinib dosing and racial groups ESMO Open. 2021 06; 6(3):100105. . View in PubMed
  • Enfortumab vedotin after PD-1 or PD-L1 inhibitors in cisplatin-ineligible patients with advanced urothelial carcinoma (EV-201): a multicentre, single-arm, phase 2 trial Lancet Oncol. 2021 06; 22(6):872-882. . View in PubMed
  • Phase II study of the histone deacetylase inhibitor vorinostat (Suberoylanilide Hydroxamic Acid; SAHA) in recurrent or metastatic transitional cell carcinoma of the urothelium – an NCI-CTEP sponsored: California Cancer Consortium trial, NCI 6879 Invest New Drugs. 2021 06; 39(3):812-820. . View in PubMed
  • A randomized phase IIa study of quantified bone scan response in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 dichloride alone or in combination with abiraterone acetate/prednisone or enzalutamide ESMO Open. 2021 04; 6(2):100082. . View in PubMed
  • Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer Prostate Cancer Prostatic Dis. 2021 03; 24(1):61-68. . View in PubMed
  • Identification of 22 susceptibility loci associated with testicular germ cell tumors Nat Commun. 2021 07 23; 12(1):4487. . View in PubMed
  • Baseline Circulating Tumor Cell Count as a Prognostic Marker of PSA Response and Disease Progression in Metastatic Castrate-Sensitive Prostate Cancer (SWOG S1216) Clin Cancer Res. 2021 04 01; 27(7):1967-1973. . View in PubMed
  • Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma N Engl J Med. 2021 08 19; 385(8):683-694. . View in PubMed
  • Circulating Tumor Cell Subtypes and T-cell Populations as Prognostic Biomarkers to Combination Immunotherapy in Patients with Metastatic Genitourinary Cancer Clin Cancer Res. 2021 03 01; 27(5):1391-1398. . View in PubMed
  • Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways Biol Open. 2021 02 25; 10(2). . View in PubMed
  • Evaluating Changes in Immune Function and Bone Microenvironment During Radium-223 Treatment of Patients with Castration-Resistant Prostate Cancer Cancer Biother Radiopharm. 2020 Sep; 35(7):485-489. . View in PubMed
  • EphrinB2 expression in prostate adenocarcinoma: Implications for targeted therapy Pathol Res Pract. 2020 Jun; 216(6):152967. . View in PubMed
  • Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel JNCI Cancer Spectr. 2020 Apr; 4(2):pkaa003. . View in PubMed
  • Protocol for a multi-centre, definitive randomised controlled trial of the effectiveness of Individual Placement and Support for employment support among people with alcohol and drug dependence Trials. 2020 Feb 11; 21(1):167. . View in PubMed
  • Safety and efficacy of CDX-014, an antibody-drug conjugate directed against T cell immunoglobulin mucin-1 in advanced renal cell carcinoma Invest New Drugs. 2020 12; 38(6):1807-1814. . View in PubMed
  • Hyperphosphatemia Secondary to the Selective Fibroblast Growth Factor Receptor 1-3 Inhibitor Infigratinib (BGJ398) Is Associated with Antitumor Efficacy in Fibroblast Growth Factor Receptor 3-altered Advanced/Metastatic Urothelial Carcinoma Eur Urol. 2020 12; 78(6):916-924. . View in PubMed
  • Programmed Death 1 and Programmed Death Ligand 1 Inhibitors in Advanced and Recurrent Urothelial Carcinoma: Meta-analysis of Single-Agent StudiesClin Genitourin Cancer. 2020 10; 18(5):351-360. e3. . View in PubMed
  • Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters JCO Clin Cancer Inform. 2020 09; 4:839-853. . View in PubMed
  • Survival outcomes and risk group validation from SWOG S0925: a randomized phase II study of cixutumumab in new metastatic hormone-sensitive prostate cancer Prostate Cancer Prostatic Dis. 2020 09; 23(3):486-493. . View in PubMed
  • Survival of African-American and Caucasian men after sipuleucel-T immunotherapy: outcomes from the PROCEED registry Prostate Cancer Prostatic Dis. 2020 09; 23(3):517-526. . View in PubMed
  • Chemoradiation for Management of Locally Recurrent or Residual Bladder Cancer: A Case Series and Review of the Literature Clin Genitourin Cancer. 2020 08; 18(4):e473-e477. . View in PubMed
  • Eligibility Criteria and Endpoints in Metastatic Renal Cell Carcinoma Trials Am J Clin Oncol. 2020 08; 43(8):559-566. . View in PubMed
  • Clinical outcomes in men of diverse ethnic backgrounds with metastatic castration-resistant prostate cancer Ann Oncol. 2020 07; 31(7):930-941. . View in PubMed
  • Editorial Comment J Urol. 2020 02; 203(2):336-337. . View in PubMed
  • Comparative prognostic implication of treatment response assessments in mCRPC: PERCIST 10, RECIST 1. 1, and PSA response criteria. Theranostics. 2020; 10(7):3254-3262. . View in PubMed
  • Infigratinib in upper tract urothelial carcinoma versus urothelial carcinoma of the bladder and its association with comprehensive genomic profiling and/or cell-free DNA results Cancer. 2020 06 01; 126(11):2597-2606. . View in PubMed
  • Cancer transcriptomic profiling from rapidly enriched circulating tumor cells Int J Cancer. 2020 05 15; 146(10):2845-2854. . View in PubMed
  • EV-101: A Phase I Study of Single-Agent Enfortumab Vedotin in Patients With Nectin-4-Positive Solid Tumors, Including Metastatic Urothelial Carcinoma J Clin Oncol. 2020 04 01; 38(10):1041-1049. . View in PubMed
  • Randomized Double-Blind Phase II Study of Maintenance Pembrolizumab Versus Placebo After First-Line Chemotherapy in Patients With Metastatic Urothelial Cancer J Clin Oncol. 2020 06 01; 38(16):1797-1806. . View in PubMed
  • Reply to Potential underestimation of cerebrovascular events in the PROVENGE Registry for the Observation, Collection, and Evaluation of Experience Data Cancer. 2020 06 15; 126(12):2935-2937. . View in PubMed
  • Local Injection of Submicron Particle Docetaxel is Associated with Tumor Eradication, Reduced Systemic Toxicity and an Immunologic Response in Uro-Oncologic Xenografts Cancers (Basel). 2019 Apr 24; 11(4). . View in PubMed
  • Randomized Phase 2 Study of Trebananib (AMG 386) with or without Continued Anti-Vascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma Who Have Progressed on Bevacizumab, Pazopanib, Sorafenib, or Sunitinib – Results of NCI/CTEP Protocol 9048 Kidney Cancer. 2019 Feb 05; 3(1):51-61. . View in PubMed
  • Accurate blood pressure during patient arm movement: the Welch Allyn Connex Spot Monitor’s SureBP algorithm Blood Press Monit. 2019 Feb; 24(1):42-44. . View in PubMed
  • Radium-223 mechanism of action: implications for use in treatment combinations Nat Rev Urol. 2019 12; 16(12):745-756. . View in PubMed
  • Prediction of Time to Hormonal Treatment Failure in Metastatic Castration-Sensitive Prostate Cancer with 18F-FDG PET/CT J Nucl Med. 2019 11; 60(11):1524-1530. . View in PubMed
  • p53 nuclear accumulation as an early indicator of lethal prostate cancer Br J Cancer. 2019 10; 121(7):578-583. . View in PubMed
  • A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma Invest New Drugs. 2019 08; 37(4):755-762. . View in PubMed
  • Randomized Phase II Trial of Abiraterone Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC)Clin Genitourin Cancer. 2019 08; 17(4):241-247. e1. . View in PubMed
  • Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers Nature. 2019 02; 566(7745):E11-E12. . View in PubMed
  • Association between precystectomy epithelial tumor marker response to neoadjuvant chemotherapy and oncological outcomes in urothelial bladder cancer Urol Oncol. 2019 01; 37(1):1-11. . View in PubMed
  • Phase II California Cancer Consortium Trial of Gemcitabine-Eribulin Combination in Cisplatin-Ineligible Patients With Metastatic Urothelial Carcinoma: Final Report (NCI-9653) J Clin Oncol. 2019 10 10; 37(29):2682-2688. . View in PubMed
  • The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of advanced renal cell carcinoma (RCC) J Immunother Cancer. 2019 12 20; 7(1):354. . View in PubMed
  • Impact of FDG PET Imaging for Expanding Patient Eligibility and Measuring Treatment Response in a Genome-Driven Basket Trial of the Pan-HER Kinase Inhibitor, Neratinib Clin Cancer Res. 2019 12 15; 25(24):7381-7387. . View in PubMed
  • Real-world outcomes of sipuleucel-T treatment in PROCEED, a prospective registry of men with metastatic castration-resistant prostate cancer Cancer. 2019 12 01; 125(23):4172-4180. . View in PubMed
  • Influence of the facility caseload on the subsequent survival of men with localized prostate cancer undergoing radical prostatectomy Cancer. 2019 11 01; 125(21):3853-3863. . View in PubMed
  • Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up Ann Oncol. 2019 06 01; 30(6):970-976. . View in PubMed
  • Multiparametric liquid biopsy analysis in metastatic prostate cancer JCI Insight. 2019 03 07; 4(5). . View in PubMed
  • Impact of timing of administration of bone supportive therapy on pain palliation from radium-223 Cancer Treat Res Commun. 2019; 18:100114. . View in PubMed
  • Phase 1 Trial of SBRT to the Prostate Fossa After Prostatectomy Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):50-60. . View in PubMed
  • Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel J Clin Oncol. 2019 02 10; 37(5):403-410. . View in PubMed
  • SIU-ICUD recommendations on bladder cancer: systemic therapy for metastatic bladder cancer World J Urol. 2019 Jan; 37(1):95-105. . View in PubMed
  • Validating the total illness burden index for prostate cancer (TIBI-CaP) in men with castration-resistant prostate cancer: data from TRUMPET Future Oncol. 2018 Mar; 14(6):527-536. . View in PubMed
  • Adjuvant Vascular Endothelial Growth Factor-targeted Therapy in Renal Cell Carcinoma: A Systematic Review and Pooled Analysis Eur Urol. 2018 11; 74(5):611-620. . View in PubMed
  • Active Surveillance for Prostate Cancer: Are We Failing Latino Patients at a Large Safety Net Hospital? Clin Genitourin Cancer. 2018 08; 16(4):e719-e727.. View in PubMed
  • Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations Cancer Discov. 2018 07; 8(7):812-821. . View in PubMed
  • Low-dimensional dynamical characterization of human performance of cancer patients using motion data Clin Biomech (BristolAvon). 2018 07; 56:61-69. . View in PubMed
  • HER kinase inhibition in patients with HER2- and HER3-mutant cancers Nature. 2018 02 08; 554(7691):189-194. . View in PubMed
  • Bone turnover biomarkers identify unique prognostic risk groups in men with castration resistant prostate cancer and skeletal metastases: Results from SWOG S0421 Cancer Treat Res Commun. 2018; 16:18-23. . View in PubMed
  • Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer J Clin Oncol. 2018 06 01; 36(16):1579-1587. . View in PubMed
  • Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival Clin Cancer Res. 2018 10 01; 24(19):4662-4671. . View in PubMed
  • Axitinib versus placebo as an adjuvant treatment of renal cell carcinoma: results from the phase III, randomized ATLAS trial Ann Oncol. 2018 12 01; 29(12):2371-2378. . View in PubMed
  • Phase III Intergroup Trial of Adjuvant Androgen Deprivation With or Without Mitoxantrone Plus Prednisone in Patients With High-Risk Prostate Cancer After Radical Prostatectomy: SWOG S9921 J Clin Oncol. 2018 05 20; 36(15):1498-1504. . View in PubMed
  • Immunomodulation by Entinostat in Renal Cell Carcinoma Patients Receiving High-Dose Interleukin 2: A Multicenter, Single-Arm, Phase I/II Trial (NCI-CTEP#7870) Clin Cancer Res. 2017 Dec 01; 23(23):7199-7208. . View in PubMed
  • Bevacizumab alone or in combination with TRC105 for patients with refractory metastatic renal cell cancer Cancer. 2017 Dec 01; 123(23):4566-4573. . View in PubMed
  • The evolution of chemotherapy for the treatment of prostate cancer Ann Oncol. 2017 Nov 01; 28(11):2658-2669. . View in PubMed
  • Baseline Glomerular Filtration Rate and Cisplatin- Induced Renal Toxicity in Urothelial Cancer Patients Clin Genitourin Cancer. 2017 Sep 06. . View in PubMed
  • Safety and Efficacy of Docetaxel, Bevacizumab, and Everolimus for Castration-resistant Prostate Cancer (CRPC) Clin Genitourin Cancer. 2017 Jul 14. . View in PubMed
  • Immunotherapy in urothelial cancer, part 2: adjuvant, neoadjuvant, and adjunctive treatment Clin Adv Hematol Oncol. 2017 Jul; 15(7):543-551. . View in PubMed
  • Immune checkpoint inhibitors in advanced renal cell carcinoma: experience to date and future directions Ann Oncol. 2017 Jul 01; 28(7):1484-1494. . View in PubMed
  • Immunotherapy in urothelial cancer, part 1: T-cell checkpoint inhibition in advanced or metastatic disease Clin Adv Hematol Oncol. 2017 Jun; 15(6):466-477. . View in PubMed
  • Safety and pharmacokinetics of cabazitaxel in patients with hepatic impairment: a phase I dose-escalation study Cancer Chemother Pharmacol. 2017 Feb; 79(2):339-351. . View in PubMed
  • Validation of the Association of RECIST Changes With Survival in Men With Metastatic Castration-Resistant Prostate Cancer Treated on SWOG Study S0421 Clin Genitourin Cancer. 2017 12; 15(6):635-641. . View in PubMed
  • A Phase II Trial of AEZS-108 in Castration- and Taxane-Resistant Prostate Cancer Clin Genitourin Cancer. 2017 12; 15(6):742-749. . View in PubMed
  • Smoke-Free Multi-unit Housing Policies Show Promise in Reducing Secondhand Smoke Exposure Among Racially and Ethnically Diverse, Low-Income Seniors J Immigr Minor Health. 2017 12; 19(6):1281-1289. . View in PubMed
  • Appropriate Use Criteria for 18F-FDG PET/CT in Restaging and Treatment Response Assessment of Malignant Disease J Nucl Med. 2017 12; 58(12):2026-2037. . View in PubMed
  • Robotic salvage retroperitoneal and pelvic lymph node dissection for ‘node-only’ recurrent prostate cancer: technique and initial series BJU Int. 2017 09; 120(3):401-408. . View in PubMed
  • Patient-reported outcomes for patients with metastatic castration-resistant prostate cancer receiving docetaxel and Atrasentan versus docetaxel and placebo in a randomized phase III clinical trial (SWOG S0421) J Patient Rep Outcomes. 2017; 2:27. . View in PubMed
  • Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma N Engl J Med. 2017 03 16; 376(11):1015-1026. . View in PubMed
  • Comparative effectiveness of screening strategies for colorectal cancer Cancer. 2017 05 01; 123(9):1516-1527. . View in PubMed
  • Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial Lancet. 2017 01 07; 389(10064):67-76. . View in PubMed
  • Isolation of exosomes from whole blood by integrating acoustics and microfluidics Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10584-10589. . View in PubMed
  • Treatment registry for outcomes in patients with castration-resistant prostate cancer (TRUMPET): a methodology for real-world evidence and research Future Oncol. 2016 Dec; 12(23):2689-2699. . View in PubMed
  • What Medical, Urologic, and Radiation Oncologists Want from Molecular Imaging of Prostate Cancer J Nucl Med. 2016 Oct; 57(Suppl 3):6S-12S. . View in PubMed
  • AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth Prostate. 2016 May; 76(6):597-608. . View in PubMed
  • Prostatectomy at high-volume centers improves outcomes and lowers the costs of care for prostate cancer Prostate Cancer Prostatic Dis. 2016 Mar; 19(1):84-91. . View in PubMed
  • Fabrication of conductive gelatin methacrylate-polyaniline hydrogels Acta Biomater. 2016 Mar; 33:122-30. . View in PubMed
  • Epidermal Growth Factor Receptor, Excision-Repair Cross-Complementation Group 1 Protein, and Thymidylate Synthase Expression in Penile CancerClin Genitourin Cancer. 2016 10; 14(5):450-456. e1. . View in PubMed
  • Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer J Clin Oncol. 2016 05 10; 34(14):1652-9. . View in PubMed
  • Docetaxel As Monotherapy or Combined With Ramucirumab or Icrucumab in Second-Line Treatment for Locally Advanced or Metastatic Urothelial Carcinoma: An Open-Label, Three-Arm, Randomized Controlled Phase II Trial J Clin Oncol. 2016 05 01; 34(13):1500-9. . View in PubMed
  • Clinical use of cabozantinib in the treatment of advanced kidney cancer: efficacy, safety, and patient selection Onco Targets Ther. 2016; 9:5825-5837. . View in PubMed
  • Paclitaxel, Ifosfamide, and Cisplatin Efficacy for First-Line Treatment of Patients With Intermediate- or Poor-Risk Germ Cell Tumors J Clin Oncol. 2016 07 20; 34(21):2478-83. . View in PubMed
  • Safety and feasibility of fasting in combination with platinum-based chemotherapy BMC Cancer. 2016 06 10; 16:360. . View in PubMed
  • Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of renal cell carcinoma J Immunother Cancer. 2016; 4:81. . View in PubMed
  • Guidelines for the definition of time-to-event end points in renal cell cancer clinical trials: results of the DATECAN project† Ann Oncol. 2015 Dec; 26(12):2392-8. . View in PubMed
  • Renal-Cell Cancer–Targeting an Immune Checkpoint or Multiple Kinases N Engl J Med. 2015 Nov 05; 373(19):1872-4. . View in PubMed
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