Keck School Faculty

Donald Barkauskas

Donald Barkauskas

Associate Professor of Clinical Population and Public Health Sciences
1845 N. Soto Street Health Sciences Campus Los Angeles

Effect of rituximab on immune status in children with mature B-cell non-Hodgkin lymphoma: a prespecified secondary analysis of the Inter-B-NHL Ritux 2010 trial Lancet Haematol. 2023 Apr 21. . View in PubMed

Crizotinib in Combination With Chemotherapy for Pediatric Patients With ALK+ Anaplastic Large-Cell Lymphoma: The Results of Children's Oncology Group Trial ANHL12P1 J Clin Oncol. 2023 Apr 10; 41(11):2043-2053. . View in PubMed

Germline Genetic Variants and Pediatric Rhabdomyosarcoma Outcomes: A Report from the Children's Oncology Group J Natl Cancer Inst. 2023 Mar 23. . View in PubMed

Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group J Clin Oncol. 2023 Feb 01; JCO2200409. . View in PubMed

Lymph node metastases in paediatric and young adult patients with non-rhabdomyosarcoma soft tissue sarcoma (NRSTS): Findings from Children's Oncology Group (COG) study ARST0332 Eur J Cancer. 2023 02; 180:89-98. . View in PubMed

Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group Clin Cancer Res. 2023 01 17; 29(2):364-378. . View in PubMed

Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group Br J Cancer. 2022 Dec; 127(12):2220-2226. . View in PubMed

Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma Int J Mol Sci. 2022 Jul 21; 23(14). . View in PubMed

Deep Learning of Rhabdomyosarcoma Pathology Images for Classification and Survival Outcome Prediction Am J Pathol. 2022 06; 192(6):917-925. . View in PubMed

Reply to RLakhotia et al. J Clin Oncol. 2022 06 20; 40(18):2064-2066. . View in PubMed

Deployment and Psychological Correlates of Suicide Ideation: A Prospective, Longitudinal Study of Risk and Resilience Among Combat Veterans Mil Med. 2021 Jan 30; 186(1-2):e58-e66. . View in PubMed

Toxicity and pharmacokinetics of actinomycin-D and vincristine in children and adolescents: Children's Oncology Group Study ADVL06B1 Cancer Chemother Pharmacol. 2021 08; 88(2):359-365. . View in PubMed

BRAF V600E/V600K Mutations versus Nonstandard Alterations: Prognostic Implications and Therapeutic Outcomes Mol Cancer Ther. 2021 06; 20(6):1072-1079. . View in PubMed

STK11 alterations in the pan-cancer setting: prognostic and therapeutic implications Eur J Cancer. 2021 05; 148:215-229. . View in PubMed

Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma JCO Precis Oncol. 2021; 5. . View in PubMed

Dose-Adjusted Etoposide, Doxorubicin, and Cyclophosphamide With Vincristine and Prednisone Plus Rituximab Therapy in Children and Adolescents With Primary Mediastinal B-Cell Lymphoma: A Multicenter Phase II Trial J Clin Oncol. 2021 11 20; 39(33):3716-3724. . View in PubMed

Germline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group J Natl Cancer Inst. 2021 07 01; 113(7):875-883. . View in PubMed

Prognostic and Therapeutic Utility of Variably Expressed Cell Surface Receptors in Osteosarcoma Sarcoma. 2021; 2021:8324348. . View in PubMed

Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium J Clin Oncol. 2021 09 10; 39(26):2859-2871. . View in PubMed

Brentuximab vedotin in combination with chemotherapy for pediatric patients with ALK+ ALCL: results of COG trial ANHL12P1 Blood. 2021 07 01; 137(26):3595-3603. . View in PubMed

Relationship between tumor mutational burden and maximum standardized uptake value in 2-[18F]FDG PET (positron emission tomography) scan in cancer patients EJNMMI Res. 2020 Dec 09; 10(1):150. . View in PubMed

High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers Mol Cancer Ther. 2020 10; 19(10):2139-2145. . View in PubMed

Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma JAMA Oncol. 2020 05 01; 6(5):724-734. . View in PubMed

Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients Int J Cancer. 2020 06 01; 146(11):3087-3097. . View in PubMed

Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children N Engl J Med. 2020 06 04; 382(23):2207-2219. . View in PubMed

ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study Cancer. 2020 12 15; 126(24):5303-5310. . View in PubMed

Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds Oncoimmunology. 2020; 9(1):1710052. . View in PubMed

Targeting fusions for improved outcomes in oncology treatment Cancer. 2020 03 15; 126(6):1315-1321. . View in PubMed

Tumor mutational burden is not predictive of cytotoxic chemotherapy response Oncoimmunology. 2020 06 24; 9(1):1781997. . View in PubMed

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Br J Cancer. 2019 Apr; 120(8):869. . View in PubMed

Relations of combat stress and posttraumatic stress disorder to 24-h plasma and cerebrospinal fluid interleukin-6 levels and circadian rhythmicity Psychoneuroendocrinology. 2019 02; 100:237-245. . View in PubMed

Factors influencing survival after recurrence in osteosarcoma: A report from the Children's Oncology Group Pediatr Blood Cancer. 2019 01; 66(1):e27444. . View in PubMed

A Phase II Study of Alisertib in Children with Recurrent/Refractory Solid Tumors or Leukemia: Children's Oncology Group Phase I and Pilot Consortium (ADVL0921) Clin Cancer Res. 2019 06 01; 25(11):3229-3238. . View in PubMed

Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children's Oncology Group Cardiooncology. 2019; 5:15. . View in PubMed

Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups J Clin Oncol. 2018 Oct 23; JCO2018789388. . View in PubMed

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Br J Cancer. 2018 08; 119(5):615-621. . View in PubMed

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients Int J Cancer. 2018 04 15; 142(8):1594-1601. . View in PubMed

The prognostic significance of circulating serum amyloid A and CXC chemokine ligand 4 in osteosarcoma Pediatr Blood Cancer. 2017 Dec; 64(12). . View in PubMed

Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma Oncotarget. 2017 Nov 14; 8(57):96738-96752. . View in PubMed

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate Clin Cancer Res. 2017 Aug 01; 23(15):4242-4250. . View in PubMed

A novel prognostic model for osteosarcoma using circulating CXCL10 and FLT3LG Cancer. 2017 Jan 01; 123(1):144-154. . View in PubMed

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation PLoS One. 2017; 12(7):e0181204. . View in PubMed

Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9. . View in PubMed

p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma Cancer Res. 2016 07 01; 76(13):4002-11. . View in PubMed

Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group Clin Cancer Res. 2016 07 15; 22(14):3643-50. . View in PubMed

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types J Natl Cancer Inst. 2015 Dec; 107(12):djv279. . View in PubMed

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma Cancer Discov. 2015 Sep; 5(9):920-31. . View in PubMed

Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma Cancer Med. 2015 Jul; 4(7):977-88. . View in PubMed

Germline TP53 variants and susceptibility to osteosarcoma J Natl Cancer Inst. 2015 Jul; 107(7). . View in PubMed

Gene Expression Profiling of Ewing Sarcoma Tumors Reveals the Prognostic Importance of Tumor-Stromal Interactions: A Report from the Children's Oncology Group J Pathol Clin Res. 2015 Apr; 1(2):83-94. . View in PubMed

Systemic levels of neuropeptide Y and dipeptidyl peptidase activity in patients with Ewing sarcoma--associations with tumor phenotype and survival Cancer. 2015 Mar 01; 121(5):697-707. . View in PubMed

The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer EuPA Open Proteom. 2015 Mar 01; 6:1-9. . View in PubMed

A summary of the osteosarcoma banking efforts: a report from the Children's Oncology Group and the QuadW Foundation Pediatr Blood Cancer. 2015 Mar; 62(3):450-5. . View in PubMed

Predictive properties of DNA methylation patterns in primary tumor samples for osteosarcoma relapse status Epigenetics. 2015; 10(1):31-9. . View in PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p1533. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. . View in PubMed

The cumulative effect of different childhood trauma types on self-reported symptoms of adult male depression and PTSD, substance abuse and health-related quality of life in a large active-duty military cohort J Psychiatr Res. 2014 Nov; 58:46-54. . View in PubMed

HER-2 expression is not prognostic in osteosarcoma; a Children's Oncology Group prospective biology study Pediatr Blood Cancer. 2014 Sep; 61(9):1558-64. . View in PubMed

Circadian rhythmicity, variability and correlation of interleukin-6 levels in plasma and cerebrospinal fluid of healthy men Psychoneuroendocrinology. 2014 Jun; 44:71-82. . View in PubMed

Response to "High BMI at diagnosis is associated with inferior survival in patients with osteosarcoma" Pediatr Blood Cancer. 2014 May; 61(5):951. . View in PubMed

Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk JAMA Psychiatry. 2014 Apr; 71(4):423-31. . View in PubMed

Analysis of serum insulin growth factor-1 concentrations in localized osteosarcoma: a children's oncology group study Pediatr Blood Cancer. 2014 Apr; 61(4):749-52. . View in PubMed

Serum glycan signatures of gastric cancer Cancer Prev Res (Phila). 2014 Feb; 7(2):226-35. . View in PubMed

Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines JAMA Psychiatry. 2014 Feb; 71(2):149-57. . View in PubMed

High-BMI at diagnosis is associated with inferior survival in patients with osteosarcoma: a report from the Children's Oncology Group Pediatr Blood Cancer. 2013 Dec; 60(12):2042-6. . View in PubMed

Characterization of cerebrospinal fluid (CSF) and plasma NPY levels in normal volunteers over a 24-h timeframe Psychoneuroendocrinology. 2013 Oct; 38(10):2378-82. . View in PubMed

Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma Neoplasia. 2013 Sep; 15(9):1049-63. . View in PubMed

Genome-wide association study identifies two susceptibility loci for osteosarcoma Nat Genet. 2013 Jul; 45(7):799-803. . View in PubMed

Outcome for adolescent and young adult patients with osteosarcoma: a report from the Children's Oncology Group Cancer. 2012 Sep 15; 118(18):4597-605. . View in PubMed

Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group J Clin Oncol. 2012 Jul 10; 30(20):2545-51. . View in PubMed

Poor survival for osteosarcoma of the pelvis: a report from the Children's Oncology Group Clin Orthop Relat Res. 2012 Jul; 470(7):2007-13. . View in PubMed

Detectable clonal mosaicism and its relationship to aging and cancer Nat Genet. 2012 May 06; 44(6):651-8. . View in PubMed

Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children's Oncology Group Cancer. 2011 Nov 01; 117(21):4966-76. . View in PubMed

A general-purpose baseline estimation algorithm for spectroscopic data Anal Chim Acta. 2010 Jan 11; 657(2):191-7. . View in PubMed

Analysis of MALDI FT-ICR mass spectrometry data: a time series approach Anal Chim Acta. 2009 Aug 26; 648(2):207-14. . View in PubMed

Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data Bioinformatics. 2009 Jan 15; 25(2):251-7. . View in PubMed

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