Francesca Mariani, PhD

Mariani Lab Website

• Skeletal Maturity and Age-Related Changes in Immune Cells and Circulatory Factors Impair Large-Scale Bone Regeneration. Aging Cell. 2025 Jul 21; e70177.. View in PubMed
• The dark side of pulmonary alveolar proteinosis. Multidiscip Respir Med. 2025 Jul 21; 20.. View in PubMed
• Hyaluronan in the pathogenesis of lung fibrosis associated to autoimmune pulmonary alveolar proteinosis (aPAP). Front Med (Lausanne). 2025; 12:1650830.. View in PubMed
• Encapsulation of Olea europaea Leaf Polyphenols in Liposomes: A Study on Their Antimicrobial Activity to Turn a Byproduct into a Tool to Treat Bacterial Infection. ACS Appl Mater Interfaces. 2024 Dec 18; 16(50):68850-68863.. View in PubMed
• Histological assessment of microtia cartilage, a potential source of autograft tissue in ear reconstruction. J Anat. 2024 08; 245(2):339-345.. View in PubMed
• Phenotypes and Serum Biomarkers in Sarcoidosis. Diagnostics (Basel). 2024 Mar 27; 14(7).. View in PubMed
• Criminal behaviors: A theory of mind problem? Appl Neuropsychol Adult. 2024 Mar 11; 1-10.. View in PubMed
• Eosinophilic cationic protein (ECP) in the clinical work-up of chronic cough. Minerva Med. 2023 Apr; 114(2):148-151.. View in PubMed
• Improving the Laboratory Diagnosis of M-like Variants Related to Alpha1-Antitrypsin Deficiency. Int J Mol Sci. 2022 Aug 30; 23(17).. View in PubMed
• A murine model of large-scale bone regeneration reveals a selective requirement for Sonic Hedgehog. NPJ Regen Med. 2022 May 17; 7(1):30.. View in PubMed
• A mini-whole lung lavage to treat autoimmune pulmonary alveolar proteinosis (PAP). Respir Res. 2022 Mar 17; 23(1):60.. View in PubMed
• The oncogenic landscape of the idiopathic pulmonary fibrosis: a narrative review. Transl Lung Cancer Res. 2022 Mar; 11(3):472-496.. View in PubMed
• On the horizon: Hedgehog signaling to heal broken bones. Bone Res. 2022 Feb 15; 10(1):13.. View in PubMed
• Hydrophobic Eutectic Solvent-Based Dispersive Liquid-Liquid Microextraction Applied to the Analysis of Pesticides in Wine. Molecules. 2022 Jan 28; 27(3).. View in PubMed
• A Systematic Review on the Antimicrobial Properties of Mediterranean Wild Edible Plants: We Still Know Too Little about Them, but What We Do Know Makes Persistent Investigation Worthwhile. Foods. 2021 Sep 18; 10(9).. View in PubMed
• COVID-19 infection in severe Alpha 1-antitrypsin deficiency: Looking for a rationale. Respir Med. 2021 07; 183:106440.. View in PubMed
• Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis. Ann Rheum Dis. 2020 12; 79(12):1625-1634.. View in PubMed
• Skeletal stem cells: insights into maintaining and regenerating the skeleton. Development. 2020 03 11; 147(5).. View in PubMed
• Multidisciplinary Approach in the Early Detection of Undiagnosed Connective Tissue Diseases in Patients With Interstitial Lung Disease: A Retrospective Cohort Study. Front Med (Lausanne). 2020; 7:11.. View in PubMed
• Sox9+ messenger cells orchestrate large-scale skeletal regeneration in the mammalian rib. Elife. 2019 04 15; 8.. View in PubMed
• The use of commercially available adhesive tapes to preserve cartilage and bone tissue integrity during cryosectioning. Biotechniques. 2018 10; 65(4):191-196.. View in PubMed
• A planar impedance sensor for 3D spheroids. Lab Chip. 2018 03 13; 18(6):933-943.. View in PubMed
• A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. Elife. 2017 10 25; 6.. View in PubMed
• Microbial Diseases of Bivalve Mollusks: Infections, Immunology and Antimicrobial Defense. Mar Drugs. 2017 Jun 17; 15(6).. View in PubMed
• Myeloperoxidase-positive cell infiltration of normal colorectal mucosa is related to body fatness and is predictive of adenoma occurrence. Int J Obes (Lond). 2017 06; 41(6):982-985.. View in PubMed
• Ectoderm-mesoderm crosstalk in the embryonic limb: The role of fibroblast growth factor signaling. Dev Dyn. 2017 04; 246(4):208-216.. View in PubMed
• Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation. Dev Biol. 2016 08 01; 416(1):82-97.. View in PubMed
• Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration. Development. 2016 06 15; 143(12):2066-76.. View in PubMed
• Lavandula angustifolia Mill. Essential Oil Exerts Antibacterial and Anti-Inflammatory Effect in Macrophage Mediated Immune Response to Staphylococcus aureus. Immunol Invest. 2016; 45(1):11-28.. View in PubMed
• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.. View in PubMed
• Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway. Stem Cell Reports. 2015 Nov 10; 5(5):866-880.. View in PubMed
• Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Dev Cell. 2015 Nov 09; 35(3):358-65.. View in PubMed
• Ogilvie’s Syndrome in an obstetric patients. Minerva Ginecol. 2015 Oct; 67(5):486-7.. View in PubMed
• Natural large-scale regeneration of rib cartilage in a mouse model. J Bone Miner Res. 2015 Feb; 30(2):297-308.. View in PubMed
• A surgical procedure for resecting the mouse rib: a model for large-scale long bone repair. J Vis Exp. 2015 Jan 21; (95):52375.. View in PubMed
• Dopamine amperometric detection at a ferrocene clicked PEDOT:PSS coated electrode. J Mater Chem B. 2014 May 21; 2(19):2861-2867.. View in PubMed
• A large kindred of pulmonary fibrosis associated with a novel ABCA3 gene variant. Respir Res. 2014 Apr 15; 15:43.. View in PubMed
• Updated embryology of the upper limb. J Hand Surg Am. 2014 Apr; 39(4):811-2.. View in PubMed
• Evidence that the limb bud ectoderm is required for survival of the underlying mesoderm. Dev Biol. 2013 Sep 15; 381(2):341-52.. View in PubMed
• Assessment and management of pulmonary alveolar proteinosis in a reference center. Orphanet J Rare Dis. 2013 Mar 13; 8:40.. View in PubMed
• Use of LysoTracker to detect programmed cell death in embryos and differentiating embryonic stem cells. J Vis Exp. 2012 Oct 11; (68).. View in PubMed
• A new Mycobacterium tuberculosis smooth colony reduces growth inside human macrophages and represses PDIM Operon gene expression. Does an heterogeneous population exist in intracellular mycobacteria? Microb Pathog. 2012 Sep; 53(3-4):135-46.. View in PubMed
• Pulmonary alveolar proteinosis: diagnostic and therapeutic challenges. Multidiscip Respir Med. 2012 Jun 11; 7(1):4.. View in PubMed
• Impaired phagocytosis in macrophages from patients affected by lysinuric protein intolerance. Mol Genet Metab. 2012 Apr; 105(4):585-9.. View in PubMed
• Spray formulation of silver and hyaluronic acid in the treatment of superficial cutaneous ulcers of different etiopathogenesis: analysis of fifty-four clinical cases. Panminerva Med. 2011 Sep; 53(3):185-91.. View in PubMed
• [Radon risk evaluation in a hospital context]. G Ital Med Lav Ergon. 2011 Jul-Sep; 33(3 Suppl):424-7.. View in PubMed
• C reactive protein and alpha1-antitrypsin: relationship between levels and gene variants. Transl Res. 2011 Jun; 157(6):332-8.. View in PubMed
• Physical properties, lung deposition modeling, and bioactivity of recombinant GM-CSF aerosolised with a highly efficient nebulizer. Pulm Pharmacol Ther. 2011 Feb; 24(1):123-7.. View in PubMed
• Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection. Cell Immunol. 2011; 271(1):1-4.. View in PubMed
• Different transcriptional profiles of human monocyte-derived dendritic cells infected with distinct strains of Mycobacterium tuberculosis and Mycobacterium bovis bacillus Calmette-Guérin. Clin Dev Immunol. 2011; 2011:741051.. View in PubMed
• In Lysinuric Protein Intolerance system y+L activity is defective in monocytes and in GM-CSF-differentiated macrophages. Orphanet J Rare Dis. 2010 Nov 26; 5:32.. View in PubMed
• Therapy options in pulmonary alveolar proteinosis. Ther Adv Respir Dis. 2010 Aug; 4(4):239-48.. View in PubMed
• The problems of clinical trials and registries in rare diseases. Respir Med. 2010 Jul; 104 Suppl 1:S42-4.. View in PubMed
• Proximal to distal patterning during limb development and regeneration: a review of converging disciplines. Regen Med. 2010 May; 5(3):451-62.. View in PubMed
• Recombinant BCG-Rv1767 amount determines, in vivo, antigen-specific T cells location, frequency, and protective outcome. Microb Pathog. 2010 May; 48(5):150-9.. View in PubMed
• Plasmapheresis for treatment of pulmonary alveolar proteinosis. Eur Respir J. 2009 May; 33(5):1220-2.. View in PubMed
• Design of immunogenic peptides from Mycobacterium tuberculosis genes expressed during macrophage infection. Tuberculosis (Edinb). 2009 May; 89(3):210-7.. View in PubMed
• Prognostic relevance of proliferative activity evaluated by Mib-1 immunostaining in node negative breast cancer. Eur J Surg Oncol. 2008 Dec; 34(12):1299-303.. View in PubMed
• Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. Nature. 2008 May 15; 453(7193):401-5.. View in PubMed
• [Implementation of a safety and health planning system in a teaching hospital]. G Ital Med Lav Ergon. 2007 Jul-Sep; 29(3 Suppl):429-31.. View in PubMed
• [Biological monitoring in oil refinery workers]. G Ital Med Lav Ergon. 2007 Jul-Sep; 29(3 Suppl):555-6.. View in PubMed
• [Retrospective analysis of the accidents causing work inability in a teaching hospital during the time 2002-2006]. G Ital Med Lav Ergon. 2007 Jul-Sep; 29(3 Suppl):634-5.. View in PubMed
• Sphingosine 1-phosphate interferes on the differentiation of human monocytes into competent dendritic cells. Scand J Immunol. 2007 Jan; 65(1):84-91.. View in PubMed
• Breast cancer local recurrence: risk factors and prognostic relevance of early time to recurrence. World J Surg. 2007 Jan; 31(1):36-45.. View in PubMed
• Transcriptional profile of the immune response in the lungs of patients with active tuberculosis. Clin Immunol. 2006 Oct; 121(1):100-7.. View in PubMed
• Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response. J Leukoc Biol. 2006 Sep; 80(3):555-62.. View in PubMed
• Gene expression profiling of human macrophages at late time of infection with Mycobacterium tuberculosis. Immunology. 2006 Aug; 118(4):449-60.. View in PubMed
• Profiling of Mycobacterium tuberculosis gene expression during human macrophage infection: upregulation of the alternative sigma factor G, a group of transcriptional regulators, and proteins with unknown function. Res Microbiol. 2006 Jun; 157(5):445-55.. View in PubMed
• An improved, real-time PCR assay for the detection of GC-rich and low abundance templates of Mycobacterium tuberculosis. J Microbiol Methods. 2006 Mar; 64(3):406-10.. View in PubMed
• [Cryosurgery with transpleurodiaphragmatic approach in the treatment of non-resectable and recurrent hepatic metastasis from the colorectum]. Suppl Tumori. 2005 May-Jun; 4(3):S44.. View in PubMed
• [Surgical resection of gastrointestinal stromal tumor after treatment with imatinib: clinical case]. Suppl Tumori. 2005 May-Jun; 4(3):S97.. View in PubMed
• Inhibitory effect of NO-releasing ciprofloxacin (NCX 976) on Mycobacterium tuberculosis survival. Antimicrob Agents Chemother. 2003 Jul; 47(7):2299-302.. View in PubMed
• Deciphering skeletal patterning: clues from the limb. Nature. 2003 May 15; 423(6937):319-25.. View in PubMed
• Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature. 2002 Aug 01; 418(6897):501-8.. View in PubMed
• Human macrophage gamma interferon decreases gene expression but not replication of Mycobacterium tuberculosis: analysis of the host-pathogen reciprocal influence on transcription in a comparison of strains H37Rv and CMT97. Infect Immun. 2001 Dec; 69(12):7262-70.. View in PubMed
• Glutamine-supplemented total parenteral nutrition in major abdominal surgery. Nutrition. 2001 Nov-Dec; 17(11-12):968-9.. View in PubMed
• Lipid modification of the Cu,Zn superoxide dismutase from Mycobacterium tuberculosis. Biochem J. 2001 Oct 01; 359(Pt 1):17-22.. View in PubMed
• The neural plate specifies somite size in the Xenopus laevis gastrula. Dev Cell. 2001 Jul; 1(1):115-26.. View in PubMed
• Initial experience with laparoscopic adjustable gastric banding and pouch dilatation: two cases. Obes Surg. 2001 Apr; 11(2):229-31.. View in PubMed
• Influence of static magnetic fields on cell viability, necrosis and apoptosis. Boll Soc Ital Biol Sper. 2001 Apr-Jun; 77(4-6):71-84.. View in PubMed
• Familial medullary thyroid carcinoma (FMTC). Study of one family (treatment criteria). Eur J Surg Oncol. 2001 Mar; 27(2):162-4.. View in PubMed
• Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells. Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26):14394-9.. View in PubMed
• Use of large-scale expression cloning screens in the Xenopus laevis tadpole to identify gene function. Dev Biol. 2000 Dec 15; 228(2):197-210.. View in PubMed
• Ras-mediated FGF signaling is required for the formation of posterior but not anterior neural tissue in Xenopus laevis. Dev Biol. 2000 Nov 01; 227(1):183-96.. View in PubMed
• Mycobacterium tuberculosis H37Rv comparative gene-expression analysis in synthetic medium and human macrophage. Gene. 2000 Aug 08; 253(2):281-91.. View in PubMed
• Expression of CCR5 is increased in human monocyte-derived macrophages and alveolar macrophages in the course of in vivo and in vitro Mycobacterium tuberculosis infection. AIDS Res Hum Retroviruses. 1999 Jul 01; 15(10):869-74.. View in PubMed
• XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue. Development. 1998 Dec; 125(24):5019-31.. View in PubMed
• Infection of human monocytes with Mycobacterium tuberculosis enhances human immunodeficiency virus type 1 replication and transmission to T cells. J Infect Dis. 1997 Jun; 175(6):1531-5.. View in PubMed
• Analysis of the adoptive transfer of delayed hypersensitivity and T cell repertoire in severe combined immunodeficiency mice reconstituted with human lymphocytes. Folia Biol (Praha). 1994; 40(6):411-30.. View in PubMed
• Characterization of an IS-like element from Mycobacterium tuberculosis. J Gen Microbiol. 1993 Aug; 139(8):1767-72.. View in PubMed
• Early immune responses to Dermatophagoides pteronyssinus and atopic predisposition. Arch Dis Child. 1992 Aug; 67(8):1023-6.. View in PubMed
• The IgG subclass antibody response to an inhalant antigen (Dermatophagoides pteronyssinus) during the first year of life: evidence for early stimulation of the immune system following natural exposure. Clin Exp Allergy. 1992 Jan; 22(1):29-33.. View in PubMed
• [Drug dependence]. Epidemiol Prev. 1991 Sep-Dec; 13(48-49):29-32.. View in PubMed
• [External plastic surgery of the pre-ostial valve in sapheno-femoral junction insufficiency. Experimental studies and clinical cases]. Phlebologie. 1991 Jul-Oct; 44(3):763-9.. View in PubMed
• [Sclerosis of the great saphenous vein: an experimental study in humans of the sclerosing effect of an iodo-iodide solution and polidodecane (histology and electron microscopy)]. Phlebologie. 1991 Apr-Jun; 44(2):461-8.. View in PubMed
• Identification of a specific Mycobacterium tuberculosis protein able to activate T lymphocytes. Ann Ist Super Sanita. 1991; 27(1):21-6.. View in PubMed
• [Inhibition by ketotifen of specific skin wheal reaction in atopic subjects]. Clin Ter. 1990 Jul 15; 134(1):47-51.. View in PubMed
• Diagnostic accuracy of sialic acid in the diagnosis of malignant ascites. Cancer. 1989 Mar 01; 63(5):912-6.. View in PubMed

• McMahon, Andrew
• Chuong, Cheng-Ming
• Chai, Yang
• Lieberman, Jay
• Warburton, David
• Crump, Gage
• Fraser, Scott
• Murry, Charles