Keck School Faculty

Frank Z Stanczyk, PhD
Frank Z Stanczyk, PhD
Research Professor of Obstetrics & Gynecology (Part-Time)
Obstetrics & Gynecology
LRB 1321 N. Mission Rd Off Campus Los Angeles
Dr. Stanczyk is the Director of the Reproductive Endocrinology Laboratory and the Co-Director of the USC Reproductive Endocrine Clinical Laboratory. A nationally recognized expert in steroid and prostaglandin biochemistry, Dr. Stanczyk is a resource to residents interested in laboratory techniques, assay methodologies, and laboratory data analyses. He oversees the Molecular Biology Core Laboratory and actively participates in resident research.

Association of Anti-Mullerian Hormone, Follicle-Stimulating Hormone and Inhibin B with Risk of Ovarian Cancer in the Janus Serum Bank Cancer Epidemiol Biomarkers Prev. 2020 Jan 13. . View in PubMed

Associations between Prediagnostic Concentrations of Circulating Sex Steroid Hormones and Liver Cancer Among Post-Menopausal Women Hepatology. 2019 Dec 05. . View in PubMed

A once-a-month oral contraceptive Sci Transl Med. 2019 Dec 04; 11(521). . View in PubMed

Age at Menarche and Risk of Cardiovascular Disease Outcomes: Findings From the National Heart Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation J Am Heart Assoc. 2019 Jun 18; 8(12):e012406. . View in PubMed

Altered pharmacokinetics of combined oral contraceptives in obesity - multistudy assessment Contraception. 2019 Apr; 99(4):256-263. . View in PubMed

Association of Prepubertal and Adolescent Androgen Concentrations With Timing of Breast Development and Family History of Breast Cancer JAMA Netw Open. 2019 02 01; 2(2):e190083. . View in PubMed

Association of urinary levels of 6-sulfatoxymelatonin (aMT6s) with prevalent and incident hypertension Chronobiol Int. 2018 08; 35(8):1115-1121. . View in PubMed

Associations between polymorphisms in genes related to estrogen metabolism and function and prostate cancer risk: results from the Prostate Cancer Prevention Trial Carcinogenesis. 2018 02 09; 39(2):125-133. . View in PubMed

Associations between postmenopausal endogenous sex hormones and C-reactive protein: a clearer picture with regional adiposity adjustment? Menopause. 2017 Sep; 24(9):1040-1048.. View in PubMed

Anastrozole in Pulmonary Arterial HypertensionA Randomized, Double-Blind, Placebo-controlled Trial. Am J Respir Crit Care Med. 2017 02 01; 195(3):360-368. . View in PubMed

Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age JAMA. 2017 10 10; 318(14):1367-1376. . View in PubMed

Associations of sex steroid hormones with mortality in women with breast cancer Breast Cancer Res Treat. 2016 Feb; 155(3):559-67. . View in PubMed

Antimüllerian hormone in relation to tobacco and marijuana use and sources of indoor heating/cooking Fertil Steril. 2016 09 01; 106(3):723-30. . View in PubMed

Assay reproducibility of serum androgen measurements using liquid chromatography-tandem mass spectrometry J Steroid Biochem Mol Biol. 2016 Jan; 155(Pt A):56-62. . View in PubMed

Associations of Breast Cancer Risk Factors with Premenopausal Sex Hormones in Women with Very Low Breast Cancer Risk Int J Environ Res Public Health. 2016 10 31; 13(11). . View in PubMed

A Prospective Evaluation of Endogenous Sex Hormone Levels and Colorectal Cancer Risk in Postmenopausal Women J Natl Cancer Inst. 2015 Oct; 107(10). . View in PubMed

Adolescent endogenous sex hormones and breast density in early adulthood Breast Cancer Res. 2015 Jun 04; 17:77. . View in PubMed

Anti-Müllerian hormone concentrations in premenopausal women and breast cancer risk Cancer Prev Res (Phila). 2015 Jun; 8(6):528-34. . View in PubMed

A prospective evaluation of C-peptide levels and colorectal adenoma incidence Cancer Epidemiol. 2015 Apr; 39(2):160-5. . View in PubMed

Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women J Clin Endocrinol Metab. 2015 Feb; 100(2):508-15. . View in PubMed

Association of estrogen measurements in serum and urine of premenopausal women Biomark Med. 2015; 9(5):417-24. . View in PubMed

Androgen deficiency and dry eye syndrome in the aging male Invest Ophthalmol Vis Sci. 2014 Jul 03; 55(8):5046-53. . View in PubMed

A pilot study examining short-term changes in bone mineral density among class 3 obese users of depot-medroxyprogesterone acetate Eur J Contracept Reprod Health Care. 2013 Jun; 18(3):199-205. . View in PubMed

Bile acid concentration reference ranges in a pregnant Latina population Am J Perinatol. 2013 May; 30(5):389-93. . View in PubMed

Association between sex hormones, glucose homeostasis, adipokines, and inflammatory markers and mammographic density among postmenopausal women Breast Cancer Res Treat. 2013 May; 139(1):255-65. . View in PubMed

Associations of serum sex steroid hormone and 5a-androstane-3a,17ß-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride Cancer Epidemiol Biomarkers Prev. 2012 Oct; 21(10):1823-32. . View in PubMed

Androstenediol complements estrogenic bioactivity during the menopausal transition Menopause. 2012 Jun; 19(6):650-7. . View in PubMed

A 12-month moderate-intensity exercise intervention does not alter serum prolactin concentrations Cancer Epidemiol. 2011 Dec; 35(6):569-73. . View in PubMed

Associations of pregnancy characteristics with maternal and cord steroid hormones, angiogenic factors, and insulin-like growth factor axis Cancer Causes Control. 2011 Nov; 22(11):1587-95. . View in PubMed

Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease Neurobiol Aging. 2011 Apr; 32(4):604-13. . View in PubMed

Antimüllerian hormone as a predictor of natural fecundability in women aged 30-42 years Obstet Gynecol. 2011 Apr; 117(4):798-804. . View in PubMed

A prospective evaluation of C-reactive protein levels and colorectal adenoma development Cancer Epidemiol Biomarkers Prev. 2011 Mar; 20(3):537-44. . View in PubMed

Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States J Steroid Biochem Mol Biol. 2011 Mar; 124(1-2):10-8. . View in PubMed

Association of functional polymorphisms in CYP19A1 with aromatase inhibitor associated arthralgia in breast cancer survivors Breast Cancer Res. 2011 Jan 20; 13(1):R8. . View in PubMed

Anthropometric, dietary, and hormonal correlates of serum adiponectin in Asian American women Nutr Cancer. 2011; 63(4):549-57. . View in PubMed

Advantages and challenges of mass spectrometry assays for steroid hormones J Steroid Biochem Mol Biol. 2010 Aug; 121(3-5):491-5. . View in PubMed

Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women Menopause. 2010 Jul; 17(4):785-90. . View in PubMed

Androgens, growth factors, and risk of prostate cancer: the Multiethnic Cohort Prostate. 2010 Jun 01; 70(8):906-15. . View in PubMed

Adolescent diet and subsequent serum hormones, breast density, and bone mineral density in young women: results of the Dietary Intervention Study in Children follow-up study Cancer Epidemiol Biomarkers Prev. 2010 Jun; 19(6):1545-56. . View in PubMed

Alberta physical activity and breast cancer prevention trial: sex hormone changes in a year-long exercise intervention among postmenopausal women J Clin Oncol. 2010 Mar 20; 28(9):1458-66. . View in PubMed

Antimullerian hormone and obesity: insights in oral contraceptive users Contraception. 2010 Mar; 81(3):245-8. . View in PubMed

Age-related changes in serum and brain levels of androgens in male Brown Norway rats Neuroreport. 2009 Nov 25; 20(17):1534-7. . View in PubMed

Associations between endogenous sex hormone levels and mammographic and bone densities in premenopausal women Cancer Causes Control. 2009 Sep; 20(7):1039-53. . View in PubMed

AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes Am J Perinatol. 2008 Oct; 25(9):577-82. . View in PubMed

Androgen and prostate cancer: is the hypothesis dead? Cancer Epidemiol Biomarkers Prev. 2008 Oct; 17(10):2525-30.. View in PubMed

3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism J Clin Endocrinol Metab. 2008 Apr; 93(4):1298-303. . View in PubMed

Associations between the CYP17, CYPIB1, COMT and SHBG polymorphisms and serum sex hormones in post-menopausal breast cancer survivors Breast Cancer Res Treat. 2007 Sep; 105(1):45-54. . View in PubMed

A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women Cancer Epidemiol Biomarkers Prev. 2007 Aug; 16(8):1601-9. . View in PubMed

ACTH stimulation in four Asian bull elephants (Elephas maximus): an investigation of androgen sources in bull elephants Gen Comp Endocrinol. 2007 May 01; 151(3):246-51. . View in PubMed

A longitudinal study of LH, gonadal and adrenal steroids in four intact Asian bull elephants (Elephas maximus) and one castrate African bull (Loxodonta africana) during musth and non-musth periods Gen Comp Endocrinol. 2007 May 01; 151(3):241-5. . View in PubMed

Acute effects of metformin therapy include improvement of insulin resistance and ovarian morphology Fertil Steril. 2007 Apr; 87(4):870-5. . View in PubMed

Alcohol and dietary fibre intakes affect circulating sex hormones among premenopausal women Public Health Nutr. 2006 Oct; 9(7):875-81. . View in PubMed

An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors Breast Cancer Res Treat. 2006 Oct; 99(3):323-31. . View in PubMed

Associations between reproductive and menstrual factors and postmenopausal androgen concentrations J Womens Health (Larchmt). 2005 Oct; 14(8):704-12. . View in PubMed

Associations among circulating sex hormones, insulin-like growth factor, lipids, and mammographic density in postmenopausal women Cancer Epidemiol Biomarkers Prev. 2005 Jun; 14(6):1411-7. . View in PubMed

Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women Cancer Epidemiol Biomarkers Prev. 2005 Jun; 14(6):1521-7. . View in PubMed

A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women Am J Clin Nutr. 2005 May; 81(5):1133-41. . View in PubMed

Bioavailability of the Yuzpe and levonorgestrel regimens of emergency contraception: vaginal vsoral administration. Contraception. 2005 Mar; 71(3):197-201. . View in PubMed

Age-related testosterone depletion and the development of Alzheimer disease JAMA. 2004 Sep 22; 292(12):1431-2. . View in PubMed

Associations between reproductive and menstrual factors and postmenopausal sex hormone concentrations Cancer Epidemiol Biomarkers Prev. 2004 Aug; 13(8):1296-301. . View in PubMed

Accelerated endometrial maturation in the luteal phase of cycles utilizing controlled ovarian hyperstimulation: impact of gonadotropin-releasing hormone agonists versus antagonists Fertil Steril. 2004 Jul; 82(1):167-71. . View in PubMed

Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women Cancer Epidemiol Biomarkers Prev. 2004 Jan; 13(1):94-101. . View in PubMed

Androgens modulate beta-amyloid levels in male rat brain J Neurochem. 2003 Nov; 87(4):1052-5. . View in PubMed

All progestins are not created equal Steroids. 2003 Nov; 68(10-13):879-90. . View in PubMed

Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women J Natl Cancer Inst. 2003 Aug 20; 95(16):1218-26. . View in PubMed

Adiposity and sex hormones in postmenopausal breast cancer survivors J Clin Oncol. 2003 May 15; 21(10):1961-6. . View in PubMed

17beta-estradiol reduces plasma Abeta40 for HRT-naïve postmenopausal women with Alzheimer disease: a preliminary study Am J Geriatr Psychiatry. 2003 Mar-Apr; 11(2):239-44. . View in PubMed

Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia J Urol. 2002 Aug; 168(2):599-604. . View in PubMed

A randomized isoflavone intervention among premenopausal women Cancer Epidemiol Biomarkers Prev. 2002 Feb; 11(2):195-201. . View in PubMed

Altered balance between the 5 alpha-reductase and aromatase pathways of androgen metabolism during controlled ovarian hyperstimulation with human menopausal gonadotropins J Assist Reprod Genet. 2001 Oct; 18(10):527-33. . View in PubMed

Body size and prostate cancer: a population-based case-control study in China Cancer Epidemiol Biomarkers Prev. 2000 Dec; 9(12):1335-41. . View in PubMed

Apoptosis may be an early event of progestin therapy for endometrial hyperplasia Gynecol Oncol. 2000 Nov; 79(2):169-76. . View in PubMed

Associations between circulating sex steroid hormones and cognition in normal elderly women Neurology. 2000 Feb 08; 54(3):599-603. . View in PubMed

Aromatase and breast cancer susceptibility Endocr Relat Cancer. 1999 Jun; 6(2):165-73. . View in PubMed

Adrenal dynamic responses to physiologic and pharmacologic adrenocorticotropic hormone stimulation before and after ovarian steroid modulation in women with polycystic ovary syndrome Fertil Steril. 1999 Mar; 71(3):439-44. . View in PubMed

Androgen metabolism and prostate cancer: establishing a model of genetic susceptibility Cancer Res. 1998 Oct 15; 58(20):4497-504. . View in PubMed

Androgens in serum and the risk of prostate cancer: a nested case-control study from the Janus serum bank in Norway Cancer Epidemiol Biomarkers Prev. 1997 Nov; 6(11):967-9. . View in PubMed

A pilot study of urinary estrogen metabolites (16alpha-OHE1 and 2-OHE1) in postmenopausal women with and without breast cancer Environ Health Perspect. 1997 Apr; 105 Suppl 3:601-5. . View in PubMed

A prevalent missense substitution that modulates activity of prostatic steroid 5alpha-reductase Cancer Res. 1997 Mar 15; 57(6):1020-2. . View in PubMed

Androgen support of lacrimal gland function Endocrine. 1997 Feb; 6(1):39-45. . View in PubMed

5 alpha-reductase activity and prostate cancer: a case-control study using stored sera Cancer Epidemiol Biomarkers Prev. 1997 Jan; 6(1):21-4. . View in PubMed

Biologic effects of 17 alpha-dihydroequilin sulfate Fertil Steril. 1996 Nov; 66(5):748-52. . View in PubMed

A cohort study of serum testosterone and hepatocellular carcinoma in Shanghai, China Int J Cancer. 1995 Nov 15; 63(4):491-3. . View in PubMed

Altered regulation of insulin-like growth factor binding protein-1 in patients with polycystic ovary syndrome J Soc Gynecol Investig. 1995 Nov-Dec; 2(6):743-7. . View in PubMed

Alterations in the sensitivity of serum insulin-like growth factor 1 and insulin-like growth factor binding protein-3 to octreotide in polycystic ovary syndrome Fertil Steril. 1995 Apr; 63(4):742-6. . View in PubMed

A prospective randomized trial comparing finasteride to spironolactone in the treatment of hirsute women J Clin Endocrinol Metab. 1995 Jan; 80(1):233-8. . View in PubMed

Alterations in androgen conjugate levels in women and men with alopecia Fertil Steril. 1994 Oct; 62(4):744-50. . View in PubMed

A possible bimodal effect of estrogen on insulin sensitivity in postmenopausal women and the attenuating effect of added progestin Fertil Steril. 1993 Oct; 60(4):664-7. . View in PubMed

Behavioral stress responses in premenopausal and postmenopausal women and the effects of estrogen Am J Obstet Gynecol. 1992 Dec; 167(6):1831-6. . View in PubMed

A reevaluation of estrogen status in postmenopausal women who smoke Am J Obstet Gynecol. 1992 May; 166(5):1444-8. . View in PubMed

5-alpha-reductase activity and risk of prostate cancer among Japanese and US white and black males Lancet. 1992 Apr 11; 339(8798):887-9. . View in PubMed

Androstenedione is an important precursor of dihydrotestosterone in the genital skin of women and is metabolized via 5 alpha-androstanedione J Steroid Biochem Mol Biol. 1990 Sep; 37(1):129-32. . View in PubMed

Androgen sulfate and glucuronide conjugates in nonhirsute and hirsute women with polycystic ovarian syndrome Am J Obstet Gynecol. 1989 Dec; 161(6 Pt 1):1704-9. . View in PubMed

A pharmacodynamic comparison of human urinary follicle-stimulating hormone and human menopausal gonadotropin in normal women and polycystic ovary syndrome Fertil Steril. 1989 Aug; 52(2):216-20. . View in PubMed

A randomized comparison of nonoral estradiol delivery in postmenopausal women Am J Obstet Gynecol. 1988 Dec; 159(6):1540-6. . View in PubMed

Alterations in sex steroid-binding protein (SBP), corticosteroid-binding globulin (CBG), and steroid hormone concentrations during pregnancy in rhesus macaques Biol Reprod. 1986 Aug; 35(1):126-32. . View in PubMed

Adrenocorticotropin-dependent virilizing paraovarian tumors in Nelson's syndrome J Clin Endocrinol Metab. 1979 Sep; 49(3):381-6. . View in PubMed

A radioimmunoassay for norethindrone (NET): measurement of serum NET concentrations following ingestion of NET-containing oral contraceptive steroids Contraception. 1978 Dec; 18(6):615-33. . View in PubMed

Bleeding and serum d-norgestrel, estradiol and progesterone patterns in women using d-norgestrel subdermal polysiloxane capsules for contraception Contraception. 1978 Apr; 17(4):315-28. . View in PubMed

A double-antibody radioimmunoassay for serum progesterone using progesterone-3-(O-carboxymethyl) oximino-[125I]-iodo-histamine as radioligand Steroids. 1978 Mar; 31(3):393-405. . View in PubMed

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