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Giselle M. Petzinger, MD

Associate Professor of Neurology (Clinical Scholar)

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Phone +1 323 442 3367
Email [email protected]
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Overview

Dr. Petzinger is a board certified neurologist specializing in the care of patients with Parkinson’s disease. She divides her time between clinical care of patients and laboratory research. The primary focus of Dr. Petzinger’s research is to better understand how to promote brain repair following injury and to translate these findings into new therapeutic treatments. Dr. Petzinger has been involved in numerous federally funded research grants. Currently, she is the principal investigator on the US Army Research Grant entitled Behaviorial and Pharmacolgical Enhancement of Neuroplasticity in Basal Ganglia of the MPTP-Lesioned Mouse and Non-Human Primate.

Publications

  • Diffusion microstructure alterations in subcortical gray matter are associated with cognitive and motor performance in Parkinson’s disease: a pilot study. Front Neurol. 2026; 17:1863964.. View in PubMed
  • Tau Disaggregation by a CNS-Permeable Small Molecule Reduces Fibril and Oligomer Burden and Preserves Proteostasis and Behavior. bioRxiv. 2026 Jun 12.. View in PubMed
  • Uncovering locomotor learning dynamics in people with Parkinson’s disease. PLoS One. 2025; 20(7):e0326692.. View in PubMed
  • Longitudinal associations between physical performance and cognition in individuals with Parkinson’s disease. Clin Park Relat Disord. 2025; 13:100370.. View in PubMed
  • Functional remapping in networks of the Parkinsonian brain: A preclinical neuroimaging perspective with clinical correlates. Transl Neurosci. 2025 Jan 01; 16(1):20250374.. View in PubMed
  • Data-driven sequence of cognitive decline in people with Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2024 11 18; 95(12):1123-1131.. View in PubMed
  • High baseline perivascular space volume in basal ganglia is associated with attention and executive function decline in Parkinson’s disease. Brain Behav. 2024 Jul; 14(7):e3607.. View in PubMed
  • A naturally occurring variant of SHLP2 is a protective factor in Parkinson’s disease. Mol Psychiatry. 2024 02; 29(2):505-517.. View in PubMed
  • Increased perivascular space volume in white matter and basal ganglia is associated with cognition in Parkinson’s Disease. Brain Imaging Behav. 2024 Feb; 18(1):57-65.. View in PubMed
  • Exercise alters cortico-basal ganglia network metabolic connectivity: a mesoscopic level analysis informed by anatomic parcellation defined in the mouse brain connectome. Brain Struct Funct. 2023 Nov; 228(8):1865-1884.. View in PubMed

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