Keck School Faculty

Giselle M Petzinger, MD
Giselle M Petzinger, MD
Associate Professor of Neurology (Clinical Scholar)
Neurology
HCC 3000 Health Sciences Campus Los Angeles
Dr. Petzinger is a board certified neurologist specializing in the care of patients with Parkinson’s disease. She divides her time between clinical care of patients and laboratory research. The primary focus of Dr. Petzinger’s research is to better understand how to promote brain repair following injury and to translate these findings into new therapeutic treatments. Dr. Petzinger has been involved in numerous federally funded research grants. Currently, she is the principal investigator on the US Army Research Grant entitled Behaviorial and Pharmacolgical Enhancement of Neuroplasticity in Basal Ganglia of the MPTP-Lesioned Mouse and Non-Human Primate.

Basal ganglia and beyond: The interplay between motor and cognitive aspects in Parkinson's disease rehabilitation Neurosci Biobehav Rev. 2018 May 04; 90:294-308. . View in PubMed

Treadmill exercise modifies dopamine receptor expression in the prefrontal cortex of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of Parkinson's disease Neuroreport. 2017 Oct 18; 28(15):987-995. . View in PubMed

The Oxygen Paradox, the French Paradox, and age-related diseases Geroscience. 2017 12; 39(5-6):499-550. . View in PubMed

Noradrenergic mechanisms of arousal's bidirectional effects on episodic memory Neurobiol Learn Mem. 2017 Jan; 137:1-14. . View in PubMed

Engaging cognitive circuits to promote motor recovery in degenerative disordersexercise as a learning modality. J Hum Kinet. 2016 Sep 01; 52:35-51. . View in PubMed

Context-Dependent Learning in People With Parkinson's Disease J Mot Behav. 2016 May-Jun; 48(3):240-8. . View in PubMed

Personality traits and the risk for Parkinson disease: a prospective study Eur J Epidemiol. 2016 Feb; 31(2):169-75. . View in PubMed

Evidence of functional brain reorganization on the basis of blood flow changes in the CAG140 knock-in mouse model of Huntington's disease Neuroreport. 2016 06 15; 27(9):632-9. . View in PubMed

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease Neurobiol Dis. 2014 Mar; 63:201-9. . View in PubMed

A kinder, gentler dopamine… highlighting dopamine's role in behavioral flexibility Front Neurosci. 2014; 8:4. . View in PubMed

Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson's disease Neuroreport. 2013 Jul 10; 24(10):509-14. . View in PubMed

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease Lancet Neurol. 2013 Jul; 12(7):716-26. . View in PubMed

The Enemy within: Propagation of Aberrant Corticostriatal Learning to Cortical Function in Parkinson's Disease Front Neurol. 2013; 4:134. . View in PubMed

Accuracy and sensitivity of Parkinsonian disorder diagnoses in two Swedish national health registers Neuroepidemiology. 2012; 38(3):186-93. . View in PubMed

How might physical activity benefit patients with Parkinson disease? Nat Rev Neurol. 2011 Jul 12; 7(9):528-34.. View in PubMed

Acute and long-term response of dopamine nigrostriatal synapses to a single, low-dose episode of 3-nitropropionic acid-mediated chemical hypoxia Synapse. 2011 Apr; 65(4):339-50. . View in PubMed

The role of exercise in facilitating basal ganglia function in Parkinson's disease Neurodegener Dis Manag. 2011 Apr 01; 1(2):157-170. . View in PubMed

MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse Parkinsons Dis. 2011; 2011:138471. . View in PubMed

Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [¹8F]fallypride Mov Disord. 2010 Dec 15; 25(16):2777-84. . View in PubMed

Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse Behav Brain Res. 2010 Dec 01; 213(2):253-62. . View in PubMed

Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease Pharmacol Biochem Behav. 2010 Jun; 95(4):466-72. . View in PubMed

Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury J Neurosci Res. 2010 Feb 15; 88(3):650-68. . View in PubMed

Enhancing neuroplasticity in the basal ganglia: the role of exercise in Parkinson's disease Mov Disord. 2010; 25 Suppl 1:S141-5. . View in PubMed

The relationships between the unified Parkinson's disease rating scale and lower extremity functional performance in persons with early-stage Parkinson's disease Neurorehabil Neural Repair. 2009 Sep; 23(7):657-61. . View in PubMed

Complete ascertainment of Parkinson disease in the Swedish Twin Registry Neurobiol Aging. 2008 Dec; 29(12):1765-73. . View in PubMed

Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury Neurobiol Dis. 2008 Nov; 32(2):319-27. . View in PubMed

Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia J Neurosci. 2008 Sep 17; 28(38):9585-97. . View in PubMed

The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease Arch Phys Med Rehabil. 2008 Jul; 89(7):1221-9. . View in PubMed

Asymmetric corticomotor excitability correlations in early Parkinson's disease Mov Disord. 2007 Aug 15; 22(11):1587-93. . View in PubMed

Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury J Neurosci. 2007 May 16; 27(20):5291-300. . View in PubMed

Behavioral motor recovery in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned squirrel monkey (Saimiri sciureus): changes in striatal dopamine and expression of tyrosine hydroxylase and dopamine transporter proteins J Neurosci Res. 2006 Feb 01; 83(2):332-47. . View in PubMed

High and low responders to novelty show differential effects in striatal glutamate Synapse. 2005 Dec 01; 58(3):200-7. . View in PubMed

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned model of parkinson's disease, with emphasis on mice and nonhuman primates Comp Med. 2004 Oct; 54(5):497-513. . View in PubMed

Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia J Neurosci Res. 2004 Aug 01; 77(3):378-90. . View in PubMed

Tyrosine hydroxylase and dopamine transporter expression following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of the mouse nigrostriatal pathway J Neurosci Res. 2004 May 15; 76(4):539-50. . View in PubMed

Human neural stem cell transplantation in the MPTP-lesioned mouse Brain Res. 2003 May 09; 971(2):168-77. . View in PubMed

Reliability and validity of a new global dyskinesia rating scale in the MPTP-lesioned non-human primate Mov Disord. 2001 Mar; 16(2):202-7. . View in PubMed

Powered by SC CTSI
Go to Top