Hossein Ameri, MD, PhD

Associate Professor of Clinical Ophthalmology

Director of USC Retinal Degeneration Center

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Overview

Dr. Hossein Ameri graduated from Tehran University of Medical Sciences and then served as a physician and managing director of Nahavand Health Network in Iran. He received his ophthalmology and vitreoretinal surgery training in Ireland, where he was also an official lecturer at University College Cork and was a founding member of the Irish Retinal Prosthesis Group. Dr. Ameri then moved to Los Angeles for a research fellowship and became an Assistant Professor of Research Ophthalmology at the Doheny Eye Institute of the University of Southern California. He was involved in preclinical studies of Argus II and the development of wide-field retinal prostheses. In addition, he produced quality research on retinal vascular disease, retinal angiogenesis, and ocular ultrasound.

Dr. Ameri completed his internship in general surgery at Cedars-Sinai Medical Center in Los Angeles and moved to Texas for his ophthalmology residency, during which he simultaneously earned a Ph.D. in neuroscience at the Graduate School of Biomedical Engineering of the University of Texas Medical Branch. Dr. Ameri obtained additional fellowship training in vitreoretinal surgery at USC Roski Eye Institute. An accomplished researcher and scholar, he has numerous peer-reviewed publications, holds a number of U.S. patents, and serves on the editorial board of journals. Currently, his lab is focused on developing gene therapy for acquired and inherited retinal diseases such as age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and retinitis pigmentosa.

Awards

  • Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch: Academic Achievement Award in Recognition of Exceptional Academic Performance, 2012
  • Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch: Senior Resident Teaching Award: Outstanding Commitment to Educating Junior Colleagues with Clinical, 2012
  • Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch: Leadership Award in Recognition of Exemplary Performance as a Resident Leader, 2012
  • Heed Ophthalmic Foundation: Heed Residents Retreat, 2011
  • Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch: Academic Achievement Award, 2011
  • Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch: Residency Academic Achievement Award, 2010
  • Department of Ophthalmology, University of Southern California: Basic Science Award, 2007
  • Association for Research in Vision and Ophthalmology: International Travel Grant Award, 2007

Publications

  • Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis Microbiol Spectr. 2024 Jun 25; e0078824. . View in PubMed
  • Comparison of The Results of Sponsored Genetic Testing Panels for Inherited Retinal Diseases J Clin Med. 2024 May 26; 13(11). . View in PubMed
  • Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis bioRxiv. 2024 Mar 19. . View in PubMed
  • Retinal Cell Biology in Health and Disease Cells. 2024 Feb 06; 13(4). . View in PubMed
  • Comparison of Retinal Metabolic Activity and Structural Development between rd10 Mice and Normal Mice Using Multiphoton Fluorescence Lifetime Imaging Microscopy Curr Issues Mol Biol. 2024 Jan 06; 46(1):612-620. . View in PubMed
  • Frequency and Pattern of Worldwide Ocular Gene Therapy Clinical Trials up to 2022 Biomedicines. 2023 Nov 23; 11(12). . View in PubMed
  • Effects of Smoothing and Adaptive Filtering in Multifocal Electroretinography (mfERG) J Clin Med. 2023 Aug 14; 12(16). . View in PubMed
  • Optical coherence tomography in healthy human subjects in the setting of prolonged dark adaptation Sci Rep. 2023 03 06; 13(1):3725. . View in PubMed
  • Hypertension: A Cause of Bilateral Proliferative Retinopathy J Curr Ophthalmol. 2022 Oct-Dec; 34(4):478-482. . View in PubMed
  • Visual Outcomes in Eyes With Neovascular Glaucoma and Anterior Segment Neovascularization Without Glaucoma Am J Ophthalmol. 2022 04; 236:1-11. . View in PubMed
  • Capillary density and caliber as assessed by optical coherence tomography angiography may be significant predictors of diabetic retinopathy severity PLoS One. 2022; 17(1):e0262996. . View in PubMed
  • Sight restoration reverses blindness-induced cross-modal functional connectivity changes between the visual and somatosensory cortex at rest Front Neurosci. 2022; 16:902866. . View in PubMed
  • Insights into Metabolic Activity and Structure of the Retina through Multiphoton Fluorescence Lifetime Imaging Microscopy in Mice Cells. 2022 07 22; 11(15). . View in PubMed
  • Ischemic index and distribution of retinal capillary non-perfusion in neovascular glaucoma Front Biosci (Landmark Ed). 2022 01 17; 27(1):24. . View in PubMed
  • Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid J Ophthalmic Vis Res. 2021 Oct-Dec; 16(4):582-591. . View in PubMed
  • Fundus Autofluorescence and Clinical Applications J Ophthalmic Vis Res. 2021 Jul-Sep; 16(3):432-461. . View in PubMed
  • Electroretinogram and Visual Field Correlation in Birdshot Chorioretinopathy Asia Pac J Ophthalmol (Phila). 2021 Feb 03; 10(2):208-211. . View in PubMed
  • Patterns of Autofluorescence in Common Genotypes of Retinitis Pigmentosa Ophthalmic Surg Lasers Imaging Retina. 2021 08; 52(8):426-431. . View in PubMed
  • Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy Transl Vis Sci Technol. 2021 05 03; 10(6):4. . View in PubMed
  • Association of the Pattern of Retinal Capillary Non-Perfusion and Vascular Leakage with Retinal Neovascularization in Proliferative Diabetic Retinopathy J Curr Ophthalmol. 2021 Jan-Mar; 33(1):56-61. . View in PubMed
  • Classification of advanced and early stages of diabetic retinopathy from non-diabetic subjects by an ordinary least squares modeling method applied to OCTA images Biomed Opt Express. 2020 Aug 01; 11(8):4666-4678. . View in PubMed
  • Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption Transl Vis Sci Technol. 2020 07; 9(8):23. . View in PubMed
  • Autofluorescence of choroidal vessels in Bietti’s crystalline dystrophy BMJ Open Ophthalmol. 2020; 5(1):e000592. . View in PubMed
  • Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina J Curr Ophthalmol. 2019 Sep; 31(3):353-356. . View in PubMed
  • Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention Pharmaceuticals (Basel). 2019 May 17; 12(2). . View in PubMed
  • Gene Therapy for Inherited Retinal Degeneration J Ocul Pharmacol Ther. 2019 03; 35(2):79-97. . View in PubMed
  • Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision Sci Rep. 2019 08 02; 9(1):11230. . View in PubMed
  • Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique Ophthalmic Surg Lasers Imaging Retina. 2019 02 01; 50(2):116-119. . View in PubMed
  • VISUAL AND ANATOMICAL OUTCOMES AFTER DIABETIC TRACTION AND TRACTION-RHEGMATOGENOUS RETINAL DETACHMENT REPAIR Retina. 2018 Oct; 38(10):1913-1919. . View in PubMed
  • Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery Am J Ophthalmol Case Rep. 2018 Jun; 10:261-263. . View in PubMed
  • Implantation of multiple suprachoroidal electrode arrays in rabbits J Curr Ophthalmol. 2018 Mar; 30(1):68-73. . View in PubMed
  • Prospect of retinal gene therapy following commercialization of voretigene neparvovec-rzyl for retinal dystrophy mediated by RPE65 mutation J Curr Ophthalmol. 2018 Mar; 30(1):1-2. . View in PubMed
  • Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation: An International Study Am J Ophthalmol. 2018 09; 193:87-99. . View in PubMed
  • OCHROCONIS GALLOPAVA ENDOPHTHALMITIS SUCCESSFULLY TREATED WITH INTRAVITREAL VORICONAZOLE AND AMPHOTERICIN B Retin Cases Brief Rep. 2018 Fall; 12(4):310-313. . View in PubMed
  • Rapid Diagnostic for Point-of-Care Malaria Screening ACS Sens. 2018 07 27; 3(7):1264-1270. . View in PubMed
  • INTRAVENOUS IMMUNOGLOBULIN IN THE TREATMENT OF JUVENILE RETINITIS PIGMENTOSA-ASSOCIATED CYSTOID MACULAR EDEMA AND UVEITIS Retin Cases Brief Rep. 2018 Summer; 12(3):242-246. . View in PubMed
  • Acute hypotony maculopathy following the initiation of a topical aqueous suppressant in a patient with a history of panuveitis without prior filtering surgery Am J Ophthalmol Case Rep. 2017 Sep; 7:95-98. . View in PubMed
  • Atypical chronic central serous chorioretinopathy with cystoid macular edema: Therapeutic response to medical and laser therapy J Curr Ophthalmol. 2017 Jun; 29(2):133-135. . View in PubMed
  • Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography PLoS One. 2017; 12(4):e0176404. . View in PubMed
  • Widefield OCT Findings of a Patient With Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis Ophthalmic Surg Lasers Imaging Retina. 2016 08 01; 47(8):774-7. . View in PubMed
  • Optical Coherence Tomography Angiography of Diabetic Retinopathy in Human Subjects Ophthalmic Surg Lasers Imaging Retina. 2015 Sep; 46(8):796-805. . View in PubMed
  • Type 3 neovascularization: evolution, association with pigment epithelial detachment, and treatment response as revealed by spectral domain optical coherence tomography Retina. 2015 Apr; 35(4):638-47. . View in PubMed
  • MULTIMODAL IMAGING OF GEOGRAPHIC AREAS OF RETINAL DARKENING Retin Cases Brief Rep. 2015; 9(4):347-51. . View in PubMed
  • Retinal prosthesis, potential future approaches Clin Exp Ophthalmol. 2014 Sep-Oct; 42(7):599-600. . View in PubMed
  • TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization Invest Ophthalmol Vis Sci. 2014 Feb 10; 55(2):801-13. . View in PubMed
  • Leuprolide monotherapy for choroidal metastasis from prostate adenocarcinoma Arch Ophthalmol. 2012 Sep; 130(9):1225-6. . View in PubMed
  • Neuroretinitis with retrobulbar involvement J Neuroophthalmol. 2011 Mar; 31(1):12-5. . View in PubMed
  • Vitreal oxygenation in retinal ischemia reperfusion Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):1035-42. . View in PubMed
  • Ultrasonic Doppler measurements of blood flow velocity of rabbit retinal vessels using a 45-MHz needle transducer Graefes Arch Clin Exp Ophthalmol. 2010 May; 248(5):675-80. . View in PubMed
  • Toward a wide-field retinal prosthesis J Neural Eng. 2009 Jun; 6(3):035002. . View in PubMed
  • Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis Graefes Arch Clin Exp Ophthalmol. 2008 Oct; 246(10):1429-39. . View in PubMed
  • Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits Retina. 2008 Feb; 28(2):350-5. . View in PubMed
  • The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5708-15. . View in PubMed
  • Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer Ultrasound Med Biol. 2007 Dec; 33(12):1971-7. . View in PubMed
  • Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro Ultrasound Med Biol. 2007 Oct; 33(10):1609-16. . View in PubMed
  • PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar; 54(3):668-75. . View in PubMed
  • Enucleated eye model for intraocular retinal prosthesis implantation Ophthalmic Surg Lasers Imaging. 2006 Jul-Aug; 37(4):341-3. . View in PubMed
  • Comparison of unilateral and simultaneous bilateral measurement of the globe position, using the Hertel exophthalmometer Ophthalmic Plast Reconstr Surg. 2004 Nov; 20(6):448-51. . View in PubMed
  • Permanent visual loss following traumatic cortical contusion Eye (Lond). 2004 Oct; 18(10):1015-6. . View in PubMed