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Imran Siddiqi, MD, PhD

Associate Professor of Clinical Pathology

Medical Director of Hematology Labs and Keck Hospital of USC and Norris Hospital

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Phone +1 323 865 0210
Email isiddiqi@usc.edu
CTSI Profile

Publications

  • T-Cell Prolymphocytic Leukemia With PDGFRB Rearrangement in the Setting of Neurofibromatosis Type 1. Int J Lab Hematol. 2025 Jun; 47(3):541-543.. View in PubMed
  • Smoothened Inhibitor, PF-04449913 Inhibits the Development of Myelofibrosis in a JAK2V617F Transgenic Mouse Model by Reducing TGF-β and MAPK Signaling Pathways. Res Sq. 2025 May 09.. View in PubMed
  • EphB4-ephrin-B2 are targets in castration resistant prostate cancer. Br J Cancer. 2025 May; 132(8):679-689.. View in PubMed
  • Analytical performance of a point-of-care CBC hematology analyzer, including a 5-part differential: A prospective study to evaluate a microfluidic flow cytometry-based analyzer in waived settings. Am J Clin Pathol. 2025 Apr 19; 163(4):531-544.. View in PubMed
  • Mantle cell lymphoma with a prominent intrasinusoidal pattern of bone marrow involvement and circulating “prolymphocytoid” cells: an unusual pathological presentation posing diagnostic pitfalls. J Hematop. 2025 Apr 15; 18(1):19.. View in PubMed
  • Validation of Electromagnetic Field Sensor Performance Through Porcine Skulls: Implications for Neurostimulation and Recording Techniques. Cureus. 2025 Apr; 17(4):e82032.. View in PubMed
  • Sporophyte-directed gametogenesis in Arabidopsis. Nat Plants. 2025 03; 11(3):398-409.. View in PubMed
  • CD10-Positive Lymphoplasmacytic Lymphoma: A Diagnostic Pitfall. Clin Lymphoma Myeloma Leuk. 2025 Jan; 25(1):23-25.. View in PubMed
  • Blast Phase of Myeloproliferative Neoplasm Resembles Acute Myeloid Leukemia, Myelodysplasia-Related, in Clinical Presentation, Cytogenetic Pattern, and Genomic Profile, and Often Undergoes Reversion to Second Chronic Phase Status After Induction Chemotherapy. Arch Pathol Lab Med. 2024 Dec 01; 148(12):1310-1319.. View in PubMed
  • Philadelphia-like B-cell acute lymphoblastic leukaemia: Disease features and outcomes in the era of immunotherapy. Br J Haematol. 2024 Dec; 205(6):2234-2247.. View in PubMed
  • How I diagnose and manage VEXAS syndrome. Am J Clin Pathol. 2024 Jul 05; 162(1):28-40.. View in PubMed
  • Erythrophagocytosis by dysplastic neutrophils and their precursors. Int J Lab Hematol. 2024 06; 46(3):423-424.. View in PubMed
  • Donor matters: Donor selection impact on hematopoietic stem cell transplantation outcomes in Hispanic patients with B-cell acute lymphocytic leukemia: Insights from a myeloablative HSCT study. Leuk Res. 2024 Jun; 141:107501.. View in PubMed
  • Post-stem cell transplant maintenance in FLT3mut acute myeloid leukemia – A retrospective analysis: Outcomes are improved with midostaurin but not with gilteritinib. EJHaem. 2024 Apr; 5(2):423-427.. View in PubMed
  • Concordance of Next-Generation Sequencing and Multiparametric Flow Cytometry Methods for Detecting Measurable Residual Disease in Adult Acute Lymphoblastic Leukemia: Optimizing Prediction of Clinical Outcomes From a Single-Center Study. Clin Lymphoma Myeloma Leuk. 2024 03; 24(3):e59-e66.e2.. View in PubMed
  • Myelokathexis in an 18-year-old male patient with severe neutropenia and lymphopenia. Am J Hematol. 2024 03; 99(3):459-460.. View in PubMed
  • Radiomics Correlation to CD68+ Tumor-Associated Macrophages in Clear Cell Renal Cell Carcinoma. Oncology. 2024; 102(3):260-270.. View in PubMed
  • Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial. Clin Cancer Res. 2023 12 15; 29(24):5087-5103.. View in PubMed
  • Spontaneous Intracerebral Hemorrhage Secondary to a Parasagittal Meningioma: A Case Report and Review of the Literature. Cureus. 2023 Oct; 15(10):e46863.. View in PubMed
  • The FANCC-FANCE-FANCF complex is evolutionarily conserved and regulates meiotic recombination. Nucleic Acids Res. 2023 04 11; 51(6):2516-2528.. View in PubMed
  • Chronic Lymphocytic Leukemia With Two B-Cell Populations of Discordant Light Chain Restrictions in Individual Patients: Parallel Development of Biclonal B-Cell Neoplasms or Clonal Evolution With Isotype Switch? Am J Clin Pathol. 2023 04 04; 159(4):337-351.. View in PubMed
  • Gut-derived Endotoxin-TLR4 Signaling Drives MYC-Ig Translocation to Promote Lymphoproliferation through c-JUN and STAT3 Activation. Mol Cancer Res. 2023 02 01; 21(2):155-169.. View in PubMed
  • EphrinB2 Inhibition and Pembrolizumab in Metastatic Urothelial Carcinoma. J Clin Oncol. 2023 01 20; 41(3):640-650.. View in PubMed
  • Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study. Oncology. 2023; 101(6):375-388.. View in PubMed
  • Cellular Mechanisms of Electromagnetic Field in Traumatic Brain Injury. J Biotechnol Biomed. 2023; 6(2):95-104.. View in PubMed
  • Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine. Clin Cancer Res. 2022 12 15; 28(24):5306-5316.. View in PubMed
  • Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma. Blood Adv. 2022 08 23; 6(16):4675-4690.. View in PubMed
  • Myeloid neoplasms in the setting of chronic lymphocytic leukaemia/chronic lymphocytic leukaemia-like disease: a clinicopathological study of 66 cases comparing cases with prior history of treatment to those without. J Clin Pathol. 2022 May; 75(5):292-301.. View in PubMed
  • Vitamin D as a modifiable risk factor, predictor, and theoretical therapeutic agent for vasospasm in spontaneous subarachnoid hemorrhage. Acta Neurol Belg. 2022 Feb; 122(1):11-15.. View in PubMed
  • Radiolucent Carbon Fiber-Reinforced Implants for Treatment of Spinal Tumors-Clinical, Radiographic, and Dosimetric Considerations. World Neurosurg. 2021 08; 152:61-70.. View in PubMed
  • Kikuchi-Fujimoto disease involving retroperitoneal lymph nodes: An uncommon presentation. Hematol Rep. 2021 Jun 09; 13(2):9001.. View in PubMed
  • Diagnosis, Management, and Treatment Options: A Cervical Spine Osteochondroma Meta-Analysis. World Neurosurg. 2021 05; 149:215-225.e6.. View in PubMed
  • First reported case of BRAF V600E mutation in T-cell prolymphocytic leukaemia. Br J Haematol. 2020 10; 191(2):e52-e55.. View in PubMed
  • Acquired Holmes Tremor in a Human Immunodeficiency Virus Immune Reconstitution Inflammatory Syndrome Patient Treated with Deep Brain Stimulation. World Neurosurg. 2020 09; 141:253-259.. View in PubMed
  • Cervical osteochondroma: surgical planning. Spinal Cord Ser Cases. 2020 05 28; 6(1):44.. View in PubMed
  • Bone Marrow Features in Patients With Acute Myeloid Leukemia Treated With Novel Targeted Isocitrate Dehydrogenase 1/2 Inhibitors. World J Oncol. 2019 Dec; 10(6):226-230.. View in PubMed
  • Response to “Gluteal Implant-Associated Anaplastic Large Cell Lymphoma (ALCL) is Distinct From Systemic ALCL ALK Negative in a Patient With Gluteal Implants”. Aesthet Surg J. 2019 09 13; 39(10):NP443.. View in PubMed
  • Response to “No Proven Association Between Anaplastic Large Cell Lymphoma (ALCL) and Textured Buttock Implants”. Aesthet Surg J. 2019 07 12; 39(8):368-369.. View in PubMed
  • The First Reported Case of Gluteal Implant-Associated Anaplastic Large Cell Lymphoma (ALCL). Aesthet Surg J. 2019 06 21; 39(7):NP253-NP258.. View in PubMed
  • Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options. World Neurosurg. 2019 Jun; 126:194-211.. View in PubMed
  • Epstein – Barr virus association with plasma cell neoplasms. Histol Histopathol. 2019 Jun; 34(6):655-662.. View in PubMed
  • Bone Marrow Findings of Immune-Mediated Pure Red Cell Aplasia Following Anti-Programmed Cell Death Receptor-1 Therapy: A Report of Two Cases and Review of Literature. J Hematol. 2019 Jun; 8(2):71-78.. View in PubMed
  • Diffuse Large B-Cell Lymphoma With Striking Intrasinusoidal Pseudoglandular Growth Pattern as a Diagnostic Dilemma Mimicking Metastatic Poorly Differentiated Pancreatic Adenocarcinoma in an Intraabdominal Lymph Node. Int J Surg Pathol. 2019 Apr; 27(2):181-184.. View in PubMed
  • BRAF V600E Mutation Across Multiple Tumor Types: Correlation Between DNA-based Sequencing and Mutation-specific Immunohistochemistry. Appl Immunohistochem Mol Morphol. 2018 Nov/Dec; 26(10):709-713.. View in PubMed
  • Monoamine oxidase A is highly expressed in classical Hodgkin lymphoma. J Pathol. 2017 10; 243(2):220-229.. View in PubMed
  • Asian-variant intravascular large B-cell lymphoma. Proc (Bayl Univ Med Cent). 2017 Apr; 30(2):186-189.. View in PubMed
  • Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging. J Clin Diagn Res. 2017 Apr; 11(4):XD01-XD03.. View in PubMed
  • Autoimmune Myelofibrosis: Clinical Features, Course, and Outcome. Acta Haematol. 2017; 138(3):129-137.. View in PubMed
  • HLA expression and HLA type associations in relation to EBV status in Hispanic Hodgkin lymphoma patients. PLoS One. 2017; 12(3):e0174457.. View in PubMed
  • Characterization of a variant of t(14;18) negative nodal diffuse follicular lymphoma with CD23 expression, 1p36/TNFRSF14 abnormalities, and STAT6 mutations. Mod Pathol. 2016 06; 29(6):570-81.. View in PubMed
  • Bone marrow cellularity MRI calculation and correlation with bone marrow biopsy. Clin Imaging. 2016 May-Jun; 40(3):392-7.. View in PubMed
  • Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases. Ann Diagn Pathol. 2016 Apr; 21:53-8.. View in PubMed
  • Pegylated interferon for the treatment of early myelofibrosis: correlation of serial laboratory studies with response to therapy. Ann Hematol. 2016 Apr; 95(5):733-8.. View in PubMed
  • Cross-platform assessment of genomic imbalance confirms the clinical relevance of genomic complexity and reveals loci with potential pathogenic roles in diffuse large B-cell lymphoma. Leuk Lymphoma. 2016; 57(4):899-908.. View in PubMed
  • Localized LECT2 amyloidosis of the adrenal gland with coexisting MGUS: a diagnostic challenge. Ann Hematol. 2015 Sep; 94(9):1603-4.. View in PubMed
  • Diffuse large B-cell lymphoma of germinal center and nongerminal center phenotypes presenting concurrently at the same anatomic site: intratumoral heterogeneity or composite lymphoma? Appl Immunohistochem Mol Morphol. 2015 Jan; 23(1):78-80.. View in PubMed
  • Autoimmune myelofibrosis: an update on morphologic features in 29 cases and review of the literature. Hum Pathol. 2014 Nov; 45(11):2183-91.. View in PubMed
  • Deep sequencing reveals lack of a clonal relationship between a metachronous classical hodgkin and diffuse large B-cell lymphoma. Clin Lymphoma Myeloma Leuk. 2014 Jun; 14(3):e87-93.. View in PubMed
  • ACTIN-RELATED PROTEIN6 Regulates Female Meiosis by Modulating Meiotic Gene Expression in Arabidopsis. Plant Cell. 2014 Apr; 26(4):1612-1628.. View in PubMed
  • Composite lymphoid neoplasm of B-cell and T-cell origins: a pathologic study of 14 cases. Hum Pathol. 2014 Apr; 45(4):768-84.. View in PubMed
  • p53 expression is a strong marker of inferior survival in de novo diffuse large B-cell lymphoma and may have enhanced negative effect with MYC coexpression: a single institutional clinicopathologic study. Am J Clin Pathol. 2014 Apr; 141(4):593-604.. View in PubMed
  • Processing the lymph node biopsy. Methods Mol Biol. 2014; 1180:271-82.. View in PubMed
  • Peripheral blood smears, bone marrow aspiration, trephine and clot biopsies: methods and protocols. Methods Mol Biol. 2014; 1180:257-69.. View in PubMed
  • Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11988-93.. View in PubMed
  • Anaplastic large cell lymphoma occurring in association with breast implants: review of pathologic and immunohistochemical features in 103 cases. Appl Immunohistochem Mol Morphol. 2013 Jan; 21(1):13-20.. View in PubMed
  • Unexpected small bowel polyposis in a man with a choledochal cyst, more than a difficult cannulation. Gastroenterology. 2012 Oct; 143(4):893, 1120.. View in PubMed
  • Spontaneous, transient regression of B lymphoblastic leukemia in an adult patient: a variant presentation of prodromal/pre-ALL. Leuk Res. 2012 Mar; 36(3):e57-9.. View in PubMed
  • Histopathological findings in 29 lymph node biopsies with increased IgG4 plasma cells. Mod Pathol. 2012 Mar; 25(3):480-91.. View in PubMed
  • 20q- clonality in a case of oral sweet syndrome and myelodysplasia. Am J Clin Pathol. 2012 Feb; 137(2):310-5.. View in PubMed
  • A small cell variant of ALK-positive, CD8-positive anaplastic large cell lymphoma with primary subcutaneous presentation mimicking subcutaneous panniculitis-like T-cell lymphoma. Pathol Res Pract. 2011 Aug 15; 207(8):522-6.. View in PubMed
  • B-cell lymphoma with hyaline vascular Castleman disease-like features: a clinicopathologic study. Am J Clin Pathol. 2011 Jun; 135(6):901-14.. View in PubMed
  • Pseudo-Pelger-Huët anomaly induced by medications: a clinicopathologic study in comparison with myelodysplastic syndrome-related pseudo-Pelger-Huët anomaly. Am J Clin Pathol. 2011 Feb; 135(2):291-303.. View in PubMed
  • Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases. Am J Hematol. 2006 Dec; 81(12):963-8.. View in PubMed

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