James D Homans, MD

Associate Professor of Clinical Pediatrics

Co-Director, MCA for Infectious Diseases and Virology

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Dr. Homans completed a combined Medicine/Pediatrics Residency Program in 1992, and subsequently an Infectious Disease Fellowship in 1994, at the LAC+USC Medical Center. He is board-certified in Pediatrics, Internal Medicine, and Infectious Disease. He has worked in the Pediatric Infectious Disease Division/MCA Program since 1997.

His current research and clinical interests include the management of congenital CMV, HIV in pregnant women, adolescents, and children as well as diagnosis and management of infectious diseases in all ages. His work involves collaboration between the departments of Pediatrics, Obstetrics/Gynecology, and Internal Medicine. In addition to his clinical work, he is a Principal Investigator at LAC+USC’s Maternal, Child, and Adolescent Program and is involved in the teaching and training of medical students, residents, mid-level providers, and foreign physicians involved in HIV care. He is a resource to physicians throughout the Los Angeles area in Pediatric Infectious Disease and HIV.


  • Maternal Syphilis Leading to High Efficiency In Utero Transmission of Antiretroviral Resistant HIV: Intersection of Two Pandemics Pediatr Infect Dis J. 2024 Jun 12. . View in PubMed
  • “We Are Not Different than Others”: A Qualitative Study of the Lived Experience of Hispanic Adolescents and Young Adults Living with Perinatally Acquired HIV Int J Environ Res Public Health. 2023 02 08; 20(4). . View in PubMed
  • Pediatric Autoimmune Encephalitis Following COVID-19 Infection J Child Neurol. 2022 03; 37(4):268-272. . View in PubMed
  • Pharmacokinetics and safety of maraviroc in neonates AIDS. 2021 03 01; 35(3):419-427. . View in PubMed
  • Systemic Immune Activation and HIV Shedding in the Female Genital Tract J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):155-62. . View in PubMed
  • An 18-year-old man with bilateral violaceous cervical adenopathy JAMA Pediatr. 2014 Aug; 168(8):773-4. . View in PubMed
  • A 14-year-old girl with hip pain and fever after a skateboard fall Pediatr Infect Dis J. 2014 Jun; 33(6):667. . View in PubMed
  • The effect of prenatal highly active antiretroviral therapy on the transmission of congenital and perinatal/early postnatal cytomegalovirus among HIV-infected and HIV-exposed infants Clin Infect Dis. 2012 Sep; 55(6):877-84. . View in PubMed
  • Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding J Acquir Immune Defic Syndr. 2012 May 01; 60(1):99-110. . View in PubMed
  • Posaconazole for chronic refractory coccidioidal meningitis Clin Infect Dis. 2011 Dec; 53(12):1252-4. . View in PubMed
  • Itraconazole treatment of nonmeningeal coccidioidomycosis in children: two case reports and review of the literature Pediatr Infect Dis J. 2010 Jan; 29(1):65-7. . View in PubMed
  • Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease J Infect Dis. 2008 Mar 15; 197(6):836-45. . View in PubMed
  • Ganciclovir population pharmacokinetics in neonates following intravenous administration of ganciclovir and oral administration of a liquid valganciclovir formulation Clin Pharmacol Ther. 2007 Jun; 81(6):867-72. . View in PubMed
  • HCV viremia is associated with drug use in young HIV-1 and HCV coinfected pregnant and non-pregnant women Addiction. 2005 May; 100(5):626-35. . View in PubMed
  • Single-dose safety and pharmacokinetics of amprenavir (141W94), a human immunodeficiency virus type 1 (HIV-1) protease inhibitor, in HIV-infected children Antimicrob Agents Chemother. 2005 Jan; 49(1):336-41. . View in PubMed
  • Tuberculosis pyomyosits of the soleus muscle in a fifteen-year-old boy Pediatr Infect Dis J. 2002 Dec; 21(12):1169-71. . View in PubMed
  • Spinal intramedullary cysticercosis in a five-year-old child: case report and review of the literature Pediatr Infect Dis J. 2001 Sep; 20(9):904-8. . View in PubMed
  • Fluconazole treatment of coccidioidal meningitis in children: two case reports and a review of the literature Pediatr Infect Dis J. 2000 Dec; 19(12):1204-8. . View in PubMed

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