Jason Ye, MD

Associate Professor of Clinical Radiation Oncology

Director of Clinical Operations, Department of Radiation Oncology at Norris Cancer Hospital

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Overview

Dr. Jason Ye is an Associate Professor of Clinical Radiation Oncology at Keck School of Medicine of USC and serves as the Director of Clinical Operations of Radiation Oncology at USC Norris Comprehensive Cancer. He joined USC in August 2016. Dr. Ye completed a seven-year accelerated liberal arts/medical (BA/MD) education from Boston University. He completed his medical doctorate degree, graduating cum laude and was also inducted into the Alpha Omega Alpha Honor Medical Society. He completed his residency in Radiation Oncology at Weill Cornell Medicine – New York Presbyterian Hospital, where he also served as Chief Resident.

Dr. Ye has presented and published studies on topics regarding breast, lung, and central nervous system cancers.  He continues to lead various research and education efforts on these and other topics at USC and collaborates with experts around the U.S. and the world. In addition, Dr. Ye aims to enhance the education of practicing providers and improve the standard of care by actively participating within various national organizations such as the American Society for Radiation Oncology (ASTRO), American Board of Radiology (ABR), American Radium Society (ARS) etc.

Dr. Ye specializes in various advanced radiation treatment techniques, such as stereotactic body radiotherapy (SBRT), biology guided radiation therapy (BGRT) intensity modulated radiation therapy (IMRT), prone breast radiotherapy, surface guided radiation therapy (SGRT) as well as stereotactic radiosurgery (SRS) including the use of Gamma Knife. His expertise in these advanced treatments allows for safe and effective curative treatments in early-stage disease, as well as definitive treatments for oligometastatic/oligoprogressive disease in late-stage disease.

Clinical Expertise: Breast, Lung, CNS tumors, Radiosurgery

Languages Spoken: English, Chinese, and Japanese

Publications

  • American Radium Society Appropriate Use Criteria Report on Radiation in the Management of Ductal Carcinoma in Situ (DCIS) of the Breast. Clin Breast Cancer. 2026 Feb; 26(2):105-112.. View in PubMed
  • Multifocal hemorrhagic metastases with cerebellar predominance following prolonged remission of pancreatic adenocarcinoma: illustrative case. J Neurosurg Case Lessons. 2025 Oct 27; 10(17).. View in PubMed
  • Stereotactic core ablative radiation therapy for small hypoxic tumors: impact of dosimetric approaches and consequent optimization strategy in the context of spatially fractionated radiation therapy. Front Oncol. 2025; 15:1568959.. View in PubMed
  • Multiparametric Dynamic Contrast Imaging for Voxelwise Quantitative Assessment of Brain Tumors. Radiol Imaging Cancer. 2025 09; 7(5):e250049.. View in PubMed
  • Factors Associated With Local Control and Toxicity of Hypofractionated Radiotherapy for Early and Late-Stage Ultracentral Lung Tumors. Clin Lung Cancer. 2025 Nov; 26(7):e572-e581.. View in PubMed
  • Physician and Software Assessed Cosmetic Outcomes Following Whole Breast or Partial Breast Radiation Therapy for Breast Cancer. Clin Breast Cancer. 2026 Jan; 26(1):157-164.. View in PubMed
  • ACR-ARS Practice Parameter for Image-Guided Radiation Therapy (IGRT). Am J Clin Oncol. 2025 11 01; 48(11):529-539.. View in PubMed
  • Multisite Benchmark Study for Standardized Relative CBV in Untreated Brain Metastases Using the DSC-MRI Consensus Acquisition Protocol. AJNR Am J Neuroradiol. 2025 03 04; 46(3):529-535.. View in PubMed
  • Interleaved flow-sensitive dephasing (iFSD): Toward enhanced blood flow suppression and preserved T1 weighting and overall signals in 3D TSE-based neuroimaging. Magn Reson Med. 2025 May; 93(5):1911-1923.. View in PubMed
  • Stereotactic radiosurgery for fourth ventricle brain metastases: tumor control outcomes and the need for CSF diversion. Patient series. J Neurosurg Case Lessons. 2024 Nov 25; 8(22).. View in PubMed