Jason Ye, MD

Associate Professor of Clinical Radiation Oncology

Director of Clinical Operations, Department of Radiation Oncology at Norris Cancer Hospital

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Dr. Jason Ye is an Associate Professor of Clinical Radiation Oncology at Keck School of Medicine of USC and serves as the Director of Clinical Operations of Radiation Oncology at USC Norris Comprehensive Cancer. He joined USC in August 2016. Dr. Ye completed a seven-year accelerated liberal arts/medical (BA/MD) education from Boston University. He completed his medical doctorate degree, graduating cum laude and was also inducted into the Alpha Omega Alpha Honor Medical Society. He completed his residency in Radiation Oncology at Weill Cornell Medicine – New York Presbyterian Hospital, where he also served as Chief Resident.

Dr. Ye has presented and published studies on topics regarding breast, lung, and central nervous system cancers.  He continues to lead various research and education efforts on these and other topics at USC and collaborates with experts around the U.S. and the world. In addition, Dr. Ye aims to enhance the education of practicing providers and improve the standard of care by actively participating within various national organizations such as the American Society for Radiation Oncology (ASTRO), American Board of Radiology (ABR), American Radium Society (ARS) etc.

Dr. Ye specializes in various advanced radiation treatment techniques, such as stereotactic body radiotherapy (SBRT), intensity modulated radiation therapy (IMRT), prone breast radiotherapy, as well as CNS stereotactic radiosurgery (SRS). His expertise in these advanced treatments allows for safe and effective curative treatments in early-stage disease, as well as definitive treatments for oligometastatic/oligoprogressive disease in late-stage disease.

Clinical Expertise:
Breast, Lung, CNS tumors, Radiosurgery

Languages Spoken:
English, Chinese, and Japanese


  • Dosimetric validation for prospective clinical trial on GRID collimator-based spatially fractionated radiation therapy: Dose metrics consistency and heterogeneous pattern reproducibility J Appl Clin Med Phys. 2024 May 29; e14410. . View in PubMed
  • Advancements and future directions in positron emission tomography-guided radiotherapy: a narrative review Chin Clin Oncol. 2024 Apr; 13(2):24. . View in PubMed
  • A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests Med Phys. 2024 Mar; 51(3):2334-2344. . View in PubMed
  • Dosimetric Validation for Prospective Clinical Trial of GRID Collimator-Based Spatially Fractionated Radiation Therapy: Dose Metrics Consistency and Heterogeneous Pattern Reproducibility Int J Radiat Oncol Biol Phys. 2024 Feb 01; 118(2):565-573. . View in PubMed
  • Mepitel film for the prevention and treatment of acute radiation dermatitis in breast cancer: a systematic review and meta-analysis of randomized controlled trials Support Care Cancer. 2023 Aug 16; 31(9):524. . View in PubMed
  • StrataXRT for the prevention of acute radiation dermatitis in breast cancer: a systematic review and meta-analysis of randomized controlled trials Support Care Cancer. 2023 Aug 09; 31(9):515. . View in PubMed
  • Adjuvant chemotherapy, not radiotherapy, prolongs survival for node-negative non-small cell lung cancer with positive surgical margins JTCVS Open. 2023 Jun; 14:472-482. . View in PubMed
  • Comparison of preoperative versus postoperative treatment dosimetry plans of single-fraction stereotactic radiosurgery for surgically resected brain metastases Neurosurg Focus. 2023 08; 55(2):E9. . View in PubMed
  • A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 15 Tesla field strength. Front Oncol. 2023; 13:1156843. . View in PubMed
  • Author Correction: Phase I trial of Bermekimab with nanoliposomal irinotecan and 5-fuorouracil/folinic acid in advanced pancreatic ductal adenocarcinoma Sci Rep. 2022 Nov 04; 12(1):18731. . View in PubMed
  • Integration of Universal Germline Genetic Testing for All New Breast Cancer Patients Ann Surg Oncol. 2022 Sep 26. . View in PubMed
  • Phase I trial of Bermekimab with nanoliposomal irinotecan and 5-fluorouracil/folinic acid in advanced pancreatic ductal adenocarcinoma Sci Rep. 2022 Sep 02; 12(1):15013. . View in PubMed
  • Making the Right Choice: Radiate Only What’s Left, the Rest is Left Int J Radiat Oncol Biol Phys. 2022 Jul 01; 113(3):491. . View in PubMed
  • Temporality and Patterns of Metastatic Recurrence in Node-Positive Breast Cancer Following Trimodality Therapy: Opportunity for Improved Oligometastases Detection and Salvage Local Therapy Am J Clin Oncol. 2022 02 01; 45(2):88-94. . View in PubMed
  • Voxelwise Prediction of Recurrent High-Grade Glioma via Proximity Estimation-Coupled Multidimensional Support Vector Machine Int J Radiat Oncol Biol Phys. 2022 04 01; 112(5):1279-1287. . View in PubMed
  • Automatic differentiation of Grade I and II meningiomas on magnetic resonance image using an asymmetric convolutional neural network Sci Rep. 2022 03 09; 12(1):3806. . View in PubMed
  • Patterns of Use of Stereotactic Body Radiation Therapy Compared With Surgery for Definitive Treatment of Primary Early-stage Non-small Cell Lung Cancer Am J Clin Oncol. 2022 04 01; 45(4):146-154. . View in PubMed
  • The abscopal effect: systematic review in patients with brain and spine metastases Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac132. . View in PubMed
  • Surviving Over a Decade With Glioblastoma: A Clinical Course Characterized by Multiple Recurrences, Numerous Salvage Treatments, and Novel Use of Cesium-131 Tiles Cureus. 2021 Nov; 13(11):e19573. . View in PubMed
  • Use of Salvage Surgery or Stereotactic Radiosurgery for Multiply Recurrent Skull Base Chordomas: A Single-Institution Experience and Review of the Literature J Neurol Surg B Skull Base. 2021 Apr; 82(2):161-174. . View in PubMed
  • “Systematic review and meta-analysis of immediate versus delayed autologous breast reconstruction in the setting of post-mastectomy adjuvant radiation therapy” J Plast Reconstr Aesthet Surg. 2021 05; 74(5):931-944. . View in PubMed
  • Automatic detection and segmentation of multiple brain metastases on magnetic resonance image using asymmetric UNet architecture Phys Med Biol. 2021 01 13; 66(1):015003. . View in PubMed
  • Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer Semin Thorac Cardiovasc Surg. 2020; 32(1):153-159. . View in PubMed
  • Stereotactic radiosurgery and ipilimumab for patients with melanoma brain metastases: clinical outcomes and toxicity J Neurooncol. 2018 Sep; 139(2):421-429. . View in PubMed
  • Integration of radiation and immunotherapy in breast cancer – Treatment implications Breast. 2018 Apr; 38:66-74. . View in PubMed
  • The relationship of dose to nerve volume in predicting pain recurrence after stereotactic radiosurgery in trigeminal neuralgia J Neurosurg. 2018 03; 128(3):891-896. . View in PubMed
  • Safety-net versus private hospital setting for brain metastasis patients treated with radiosurgery alone: Disparities in follow-up care and outcomes Cancer. 2018 Jan 01; 124(1):167-175. . View in PubMed
  • In Regard to Ahmed et al Int J Radiat Oncol Biol Phys. 2016 Apr 01; 94(5):1221-2. . View in PubMed
  • Multi-Institutional Implementation and Evaluation of a Curriculum for the Medical Student Clerkship in Radiation Oncology J Am Coll Radiol. 2016 Feb; 13(2):203-9. . View in PubMed
  • Equivalent Survival With Mastectomy or Breast-conserving Surgery Plus Radiation in Young Women Aged < 40 Years With Early-Stage Breast Cancer: A National Registry-based Stage-by-Stage Comparison Clin Breast Cancer. 2015 Oct; 15(5):390-7. . View in PubMed
  • Daily patient setup error in prostate image guided radiation therapy with fiducial-based kilovoltage onboard imaging and conebeam computed tomography Quant Imaging Med Surg. 2015 Oct; 5(5):665-72. . View in PubMed
  • Medical Student Perspectives on a Multi-institutional Clerkship Curriculum: A Report From the Radiation Oncology Education Collaborative Study Group Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):217-9. . View in PubMed
  • Second cancer, breast cancer, and cardiac mortality in stage T1aN0 breast cancer patients with or without external beam radiation therapy: a national registry study Clin Breast Cancer. 2015 Feb; 15(1):54-9. . View in PubMed
  • Clinical correlation of previously undetected cancer-related incidental findings on CT planning scans for radiation therapy AJR Am J Roentgenol. 2011 Nov; 197(5):1160-3. . View in PubMed
  • Implications of previously undetected incidental findings on 3D CT simulation scans for radiation therapy Pract Radiat Oncol. 2011 Jan-Mar; 1(1):22-6. . View in PubMed
  • Spinal cord complications after thoracic aortic surgery: long-term survival and functional status varies with deficit severity J Vasc Surg. 2008 Jul; 48(1):47-53. . View in PubMed