Jeannie Chen, PhD

Professor of Physiology and Neuroscience

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Publications

Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington’s disease. Neurobiol Dis. 2025 02; 205:106780.. View in PubMed
Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors. Curr Biol. 2024 04 08; 34(7):1492-1505.e6.. View in PubMed
Arrestin Facilitates Rhodopsin Dephosphorylation in Vivo. J Neurosci. 2022 04 27; 42(17):3537-3545.. View in PubMed
Two Peeling Methods for the Isolation of Photoreceptor Cell Compartments in the Mouse Retina for Protein Analysis. J Vis Exp. 2021 12 07; (178).. View in PubMed
The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx. J Biol Chem. 2018 10 05; 293(40):15332-15346.. View in PubMed
Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration. Exp Eye Res. 2018 02; 167:56-90.. View in PubMed
Separation of photoreceptor cell compartments in mouse retina for protein analysis. Mol Neurodegener. 2017 04 11; 12(1):28.. View in PubMed
Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods. J Neurosci. 2016 06 29; 36(26):6973-87.. View in PubMed
Induction of the unfolded protein response by constitutive G-protein signaling in rod photoreceptor cells. J Biol Chem. 2014 Oct 17; 289(42):29310-21.. View in PubMed