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Jesse A. Goodrich, PhD

Assistant Professor of Population and Public Health Sciences

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Overview

Dr. Jesse Goodrich is an Assistant Professor in the Division of Environmental Health at the University of Southern California. His research combines data on environmental exposures with information on molecular-level biological processes to understand the effects of environmental pollutants on the risk of obesity, type 2 diabetes, and cancer. He is particularly interested in examining these questions in children and adolescents because they may be more susceptible to the adverse health effects of environmental pollutants.

Research Funding

  • PFAS Exposure and Diabetic Kidney Disease in Youth with Type 2 Diabetes: A Multi-Omic Approach for Prevention and Treatment
    NIH · R01DK140831 · Sep 10, 2024 – Jun 30, 2029 · Role: Principal Investigator
  • PFAS and Diabetic Kidney Disease in Young Onset Type 2 Diabetes: Emerging Risk Factors and Underlying Mechanisms
    NIH · K01ES036193 · Apr 16, 2024 – Mar 31, 2027 · Role: Principal Investigator

Publications

  • Spatial Organization of Male Mouse Thick Ascending Limb Cell Types. J Am Soc Nephrol. 2026 Sep 24.. View in PubMed
  • Marine microplastic pollution and cancer incidence from 2013 to 2021 in US coastal counties: an ecological analysis. Int J Hyg Environ Health. 2026 Sep 11; 278:114903.. View in PubMed
  • SGLT2 inhibition modulates metabolic, vascular, and inflammatory molecular markers in the kidney in youth with type 1 diabetes. Sci Transl Med. 2026 Jul 22; 18(859):eaee1005.. View in PubMed
  • Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study. J Clin Endocrinol Metab. 2026 Jul 15.. View in PubMed
  • Prediagnostic Plasma Metabolite Profiles and Prediction of Hepatocellular Carcinoma Risk: The Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev. 2026 Jul 01; 35(7):1110-1119.. View in PubMed
  • Annotation-Based Gene-Peak Links Improve Regulatory Network Prediction of Gene Expression in Human Kidney Multi-Omics. bioRxiv. 2026 Jun 17.. View in PubMed
  • Praxis-BGM: clustering of omics data using semi-supervised transfer learning for Gaussian mixture models via natural-gradient variational inference. Bioinformatics. 2026 Jun 01; 42(6).. View in PubMed
  • Metabolites and proteins may mediate the relationship between diet quality and insulin sensitivity in young adult cohort. J Diabetes Metab Disord. 2026 Jun; 25(1):90.. View in PubMed
  • Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK/STAT signaling. J Clin Invest. 2026 Apr 01; 136(7).. View in PubMed
  • Developmental perfluorooctane sulfonate (PFOS) exposure alters gene expression in nucleus accumbens and prefrontal cortex and impairs cognition in rats: A transcriptomic and mediation analysis. Ecotoxicol Environ Saf. 2026 Jan 01; 309:119648.. View in PubMed

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