Erythrocyte omega-3 index, ambient fine particle exposure, and brain aging Neurology. 2020 08 25; 95(8):e995-e1007. . View in PubMed
Reduced risk of all-cancer and solid cancer in Taiwanese patients with rheumatoid arthritis treated with etanercept, a TNF-a inhibitor Medicine (Baltimore). 2017 Feb; 96(7):e6055. . View in PubMed
Increased risk of a suicide event in patients with primary fibromyalgia and in fibromyalgia patients with concomitant comorbidities: A nationwide population-based cohort study Medicine (Baltimore). 2016 Nov; 95(44):e5187. . View in PubMed
Randomized comparison of group versus individual educational interventions for pregnant women to reduce their secondhand smoke exposure Medicine (Baltimore). 2016 Oct; 95(40):e5072. . View in PubMed
Increased Risk of Stroke in Patients With Fibromyalgia: A Population-BASED Cohort Study Medicine (Baltimore). 2016 Feb; 95(8):e2860. . View in PubMed
Blood Pressure, Carotid Flow Pulsatility, and the Risk of Stroke: A Community-Based Study Stroke. 2016 09; 47(9):2262-8. . View in PubMed
Diagnostic Arthrocentesis for Suspicion of Gout Is Safe and Well Tolerated J Rheumatol. 2016 Jan; 43(1):150-3. . View in PubMed
Sleep duration, cognitive decline, and dementia risk in older women Alzheimers Dement. 2016 Jan; 12(1):21-33. . View in PubMed
An Independent Risk of Gout on the Development of Deep Vein Thrombosis and Pulmonary Embolism: A Nationwide, Population-Based Cohort Study Medicine (Baltimore). 2015 Dec; 94(51):e2140. . View in PubMed
Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study J Rheumatol. 2015 Sep; 42(9):1694-701. . View in PubMed
At USC, Chen developed the AirPollBrain Network (Co-PIs: Finch & Chen), with its mission to create a research and education program in environmental neurosciences of brain health during development and aging in urban environments. To study how ambient air pollution exposures affect brain aging including Alzheimer’s disease (AD), Dr. Chen’s research team and their collaborators take the team-sciences approach that integrates state-of-the-art knowledge and tools in neurobiology of AD, population & clinical neuroimaging, mouse brain imaging, neuroinformatics and high-dimensional data analyses, brain vascular biology, inhalation exposure assessment and neurotoxicology, clinical neurology and neurosurgery, cognitive neurosciences and neuropsychology, quantitative psychology, epidemiology of AD, spatial statistics, and air pollution epidemiology.
These powerful approaches had been expanded to study how urban environmental adversities shape the neurodevelopmental and behavioral trajectories during vulnerable time periods. Chen’s team also pioneers the emerging field of environmental health disparities in AD and related dementias, investigating how environmental stressors and resilience factors interact to shape the socio-geographic disparities in dementia.