Katherine E Lawrence

Assistant Professor Of Research Neurology

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Overview

The overarching aim of my research is to improve our understanding of the neural mechanisms underlying neurodevelopmental conditions, with the long-term goal of contributing to personalized medicine approaches for interested individuals. My work leverages large-scale multimodal neuroimaging data — including diffusion-weighted MRI and resting-state functional MRI — together with advanced imaging and statistical methods. My primary line of research characterizes the neurobiological underpinnings of brain-based conditions such as autism and attention-deficit/hyperactivity disorder (ADHD). In my other main branch of research, I investigate typical brain development and moderating factors in large-scale population-based samples.

Publications

  • Structural brain alterations in autism: A large-scale voxel-based morphometry mega-analysis. bioRxiv. 2026 Jul 04.. View in PubMed
  • Lifespan normative modeling of brain microstructure. Nat Commun. 2026 May 27; 17(1).. View in PubMed
  • The Regional Vulnerability Index (RVI) as a Neuroimaging-Based Biomarker for Autism: Associations with Likelihood, Cognition, and Longitudinal Social Outcomes. bioRxiv. 2026 May 26.. View in PubMed
  • Infant subcortical brain volumes associated with maternal obesity and diabetes: a large multicohort human study. BMC Med. 2026 Apr 16; 24(1).. View in PubMed
  • Triple-Network Functional Connectivity in Adolescents With Autism Spectrum Disorder Compared to Early-Onset Psychosis. Autism Res. 2026 04; 19(4):e70163.. View in PubMed
  • Mapping along-tract commissural and association white matter microstructural differences in autistic children and young adults. Cereb Cortex. 2025 Nov 01; 35(11).. View in PubMed
  • Lifespan Normative Modeling of Brain Microstructure. bioRxiv. 2025 Oct 04.. View in PubMed
  • Infant Subcortical Brain Volumes Associated with Maternal Obesity and Diabetes: A Large Multicohort Study. medRxiv. 2025 Mar 27.. View in PubMed
  • Mapping Along-Tract White Matter Microstructural Differences in Autism. bioRxiv. 2025 Mar 24.. View in PubMed
  • A worldwide study of white matter microstructural alterations in people living with Parkinson’s disease. NPJ Parkinsons Dis. 2024 Aug 11; 10(1):151.. View in PubMed
  • Sex Differences in the Brain’s White Matter Microstructure during Development assessed using Advanced Diffusion MRI Models. Annu Int Conf IEEE Eng Med Biol Soc. 2024 Jul; 2024:1-7.. View in PubMed
  • Sex Differences in the Brain’s White Matter Microstructure during Development assessed using Advanced Diffusion MRI Models. bioRxiv. 2024 Apr 30.. View in PubMed
  • Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism. Commun Biol. 2024 04 22; 7(1):485.. View in PubMed
  • Collecting patient-reported outcome measures in the electronic health record: Lessons from the NIH pragmatic trials Collaboratory. Contemp Clin Trials. 2024 02; 137:107426.. View in PubMed
  • Associations among prenatal exposure to gestational diabetes mellitus, brain structure, and child adiposity markers. Obesity (Silver Spring). 2023 11; 31(11):2699-2708.. View in PubMed
  • Releasing and tracking the distribution of adventive Trissolcus japonicus (Hymenoptera: Scelionidae) in Virginia. Environ Entomol. 2023 08 18; 52(4):583-592.. View in PubMed
  • Few-Shot Classification of Autism Spectrum Disorder using Site-Agnostic Meta-Learning and Brain MRI. Annu Int Conf IEEE Eng Med Biol Soc. 2023 07; 2023:1-6.. View in PubMed
  • Few-Shot Classification of Autism Spectrum Disorder using Site-Agnostic Meta-Learning and Brain MRI. ArXiv. 2023 Mar 14.. View in PubMed
  • White matter microstructure shows sex differences in late childhood: Evidence from 6797 children. Hum Brain Mapp. 2023 02 01; 44(2):535-548.. View in PubMed
  • Short-term outcomes of the Therapist-assisted Online Parenting Strategies intervention for parents of adolescents treated for anxiety and/or depression: A single-arm double-baseline trial. Aust N Z J Psychiatry. 2022 06; 56(6):695-708.. View in PubMed
  • Impact of autism genetic risk on brain connectivity: a mechanism for the female protective effect. Brain. 2022 03 29; 145(1):378-387.. View in PubMed
  • Age and sex effects on advanced white matter microstructure measures in 15,628 older adults: A UK biobank study. Brain Imaging Behav. 2021 Dec; 15(6):2813-2823.. View in PubMed
  • Sex Differences in Salience Network Connectivity and its Relationship to Sensory Over-Responsivity in Youth with Autism Spectrum Disorder. Autism Res. 2020 09; 13(9):1489-1500.. View in PubMed
  • Sex Differences in Functional Connectivity of the Salience, Default Mode, and Central Executive Networks in Youth with ASD. Cereb Cortex. 2020 07 30; 30(9):5107-5120.. View in PubMed
  • Neural responsivity to social rewards in autistic female youth. Transl Psychiatry. 2020 06 02; 10(1):178.. View in PubMed
  • Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity. Transl Psychiatry. 2020 03 03; 10(1):82.. View in PubMed
  • Social Attention in Autism: Neural Sensitivity to Speech Over Background Noise Predicts Encoding of Social Information. Front Psychiatry. 2020; 11:343.. View in PubMed
  • Distinct Patterns of Neural Habituation and Generalization in Children and Adolescents With Autism With Low and High Sensory Overresponsivity. Am J Psychiatry. 2019 12 01; 176(12):1010-1020.. View in PubMed
  • Investigating the prevalence of dissociative disorders and severe dissociative symptoms in first episode psychosis. Early Interv Psychiatry. 2019 12; 13(6):1366-1372.. View in PubMed
  • Off-label Use in Ambulatory Paediatric Clinics in a Central South African Hospital. J Trop Pediatr. 2019 08 01; 65(4):380-388.. View in PubMed
  • Atypical longitudinal development of functional connectivity in adolescents with autism spectrum disorder. Autism Res. 2019 01; 12(1):53-65.. View in PubMed
  • The Impact of a National Competency-Based Medical Education Initiative in Family Medicine. Acad Med. 2018 12; 93(12):1850-1857.. View in PubMed
  • Does dissociation mediate the relationship between childhood trauma and hallucinations, delusions in first episode psychosis? Compr Psychiatry. 2018 07; 84:68-74.. View in PubMed
  • Hemispheric brain asymmetry differences in youths with attention-deficit/hyperactivity disorder. Neuroimage Clin. 2018; 18:744-752.. View in PubMed
  • Aberrant Dynamic Connectivity for Fear Processing in Anorexia Nervosa and Body Dysmorphic Disorder. Front Psychiatry. 2018; 9:273.. View in PubMed
  • Relationship between preparation of cells for therapy and cell quality using artificial neural network analysis. Artif Intell Med. 2014 Oct; 62(2):119-27.. View in PubMed
  • White matter microstructure in subjects with attention-deficit/hyperactivity disorder and their siblings. J Am Acad Child Adolesc Psychiatry. 2013 Apr; 52(4):431-440.e4.. View in PubMed