Keith Hazleton

Assistant Professor of Clinical Pediatrics

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Publications

  • A Multimodal Intervention to Reduce Cdifficile Infections and Stool Testing. Pediatrics. 2024 Mar 01; 153(3). . View in PubMed
  • Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice NPJ Biofilms Microbiomes. 2022 04 01; 8(1):15. . View in PubMed
  • Gastric injury secondary to button battery ingestions: a retrospective multicenter review Gastrointest Endosc. 2020 Aug; 92(2):276-283. . View in PubMed
  • Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota Antimicrob Agents Chemother. 2019 12 20; 64(1). . View in PubMed
  • Low diversity gut microbiota dysbiosis: drivers, functional implications and recovery Curr Opin Microbiol. 2018 08; 44:34-40. . View in PubMed
  • Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases J Biol Chem. 2013 Nov 29; 288(48):34746-54. . View in PubMed
  • Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase Bioorg Med Chem. 2013 Sep 01; 21(17):5629-46. . View in PubMed
  • Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase Chem Biol. 2012 Jun 22; 19(6):721-30. . View in PubMed
  • Purine and pyrimidine pathways as targets in Plasmodium falciparum Curr Top Med Chem. 2011; 11(16):2103-15. . View in PubMed
  • Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model PLoS One. 2011; 6(11):e26916. . View in PubMed
  • Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1 Mol Biochem Parasitol. 2010 Jan; 169(1):40-9. . View in PubMed
  • Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum J Biol Chem. 2008 Nov 21; 283(47):32889-99. . View in PubMed
  • Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition Biochemistry. 2007 Oct 30; 46(43):12405-15. . View in PubMed
  • Structural characterization of the fusion of two pentapeptide repeat proteins, Np275 and Np276, from Nostoc punctiforme: resurrection of an ancestral protein Protein Sci. 2007 Apr; 16(4):755-60. . View in PubMed