Ksenia Gnedeva, PhD

Assistant Professor of Otolaryngology - Head and Neck Surgery and Stem Cell Biology & Regenerative Medicine

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Overview

Publications

  • Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and diseaseCell Stem Cell. 2024 Jun 06; 31(6):921-939. e17. . View in PubMed
  • Large-scale annotated dataset for cochlear hair cell detection and classification Sci Data. 2024 Apr 23; 11(1):416. . View in PubMed
  • Obtaining High-Quality Cryosections of Whole Rabbit Eye J Vis Exp. 2023 Nov 10; (201). . View in PubMed
  • Large-scale annotated dataset for cochlear hair cell detection and classification bioRxiv. 2023 Sep 01. . View in PubMed
  • Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids bioRxiv. 2023 May 25. . View in PubMed
  • SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2301301120. . View in PubMed
  • Role of YAP in early ectodermal specification and a Huntington’s Disease model of human neurulation Elife. 2022 04 22; 11. . View in PubMed
  • Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2206113119. . View in PubMed
  • Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues Nat Commun. 2021 05 25; 12(1):3100. . View in PubMed
  • Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13552-13561. . View in PubMed
  • Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs J Vis Exp. 2018 06 01; (136). . View in PubMed
  • Elastic force restricts growth of the murine utricle Elife. 2017 07 25; 6. . View in PubMed
  • SoxC transcription factors are essential for the development of the inner ear Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):14066-71. . View in PubMed
  • Derivation of hair-inducing cell from human pluripotent stem cells PLoS One. 2015; 10(1):e0116892. . View in PubMed
  • Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis Cell Stem Cell. 2011 May 06; 8(5):538-51. . View in PubMed