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Kyle M. Hurth, MD, PhD

Associate Professor of Clinical Pathology

Program Director, Neuropathology Fellowship Program

Immunohistochemistry Laboratory Director

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Phone +1 323 442 8592
Email hurth@med.usc.edu
CTSI Profile

Publications

  • Multifocal intra-cranial masses: Late presentation of an uncommon histiocytic disorder Radiol Case Rep. 2025 Nov; 20(11):5610-5614. . View in PubMed
  • A contemporary, multiinstitutional analysis of transcription factor lineage in pituitary adenomas: comparative study of neuroimaging, histopathology, and clinical outcomes J Neurosurg. 2025 Jul 01; 143(1):146-154. . View in PubMed
  • Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas Nat Commun. 2025 Jun 13; 16(1):5290. . View in PubMed
  • Association between meningioma consistency and surgical outcomes J Neurosurg. 2025 May 01; 142(5):1331-1337. . View in PubMed
  • Evidence for cPLA2 activation in Alzheimer’s Disease Synaptic Pathology bioRxiv. 2025 Apr 01. . View in PubMed
  • The role of plasma metagenomic sequencing in identification of Balamuthia mandrillaris encephalitis Acta Neuropathol Commun. 2025 03 13; 13(1):60. . View in PubMed
  • Successful Multimodal Management of an Aggressive Functional Gonadotropic Pituitary Macroadenoma AACE Clin Case Rep. 2025 Jan-Feb; 11(1):14-17. . View in PubMed
  • Intracranial meningioma: A review of recent and emerging data on the utility of preoperative imaging for management J Neuroimaging. 2024 Sep-Oct; 34(5):527-547. . View in PubMed
  • A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests Med Phys. 2024 Mar; 51(3):2334-2344. . View in PubMed
  • Recurring homozygous ACTN2 variant (pArg506Gly) causes a recessive myopathy. Ann Clin Transl Neurol. 2024 Mar; 11(3):629-640. . View in PubMed
  • Neurotropism of SARS-CoV-2: A Pathological Examination of Neurosurgical Specimens Neurosurgery. 2024 02 01; 94(2):379-388. . View in PubMed
  • Clinical Implications of Pituitary Adenomas Exhibiting Dual Transcription Factor Staining: A Case Series of 27 Patients World Neurosurg. 2024 02; 182:e62-e66. . View in PubMed
  • Breast-to-brain metastasis is exacerbated with chemotherapy through blood-cerebrospinal fluid barrier and induces Alzheimer’s-like pathology J Neurosci Res. 2023 12; 101(12):1900-1913. . View in PubMed
  • ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis Clin Cancer Res. 2023 11 01; 29(21):4492-4503. . View in PubMed
  • Prevalence of Frontotemporal Dementia in Females of 5 Hispanic Families With R159H VCP Multisystem Proteinopathy Neurol Genet. 2023 Feb; 9(1):e200037. . View in PubMed
  • Highly Multiplexed Spatially Resolved Proteomic and Transcriptional Profiling of the Glioblastoma Microenvironment Using Archived Formalin-Fixed Paraffin-Embedded Specimens Mod Pathol. 2023 01; 36(1):100034. . View in PubMed
  • Detection of perillyl alcohol and its metabolite perillic acid in postsurgical glioblastoma tissue after intranasal administration of NEO100: illustrative case J Neurosurg Case Lessons. 2022 Aug 22; 4(8). . View in PubMed
  • Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer’s disease Neurobiol Aging. 2022 04; 112:39-54. . View in PubMed
  • Automatic differentiation of Grade I and II meningiomas on magnetic resonance image using an asymmetric convolutional neural network Sci Rep. 2022 03 09; 12(1):3806. . View in PubMed
  • Silent corticotroph pituitary adenomas: clinical characteristics, long-term outcomes, and management of disease recurrence J Neurosurg. 2021 12 01; 135(6):1706-1713. . View in PubMed
  • Monoclonal Antibody Therapy against Acinetobacter baumannii Infect Immun. 2021 09 16; 89(10):e0016221. . View in PubMed
  • Reducing body myopathy associated with the LIM2 p(His123Arg) FHL1 variant. Clin Neurol Neurosurg. 2021 08; 207:106795. . View in PubMed
  • Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination Cell Rep. 2021 Jul 27; 36(4):109475. . View in PubMed
  • Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination Cell Rep. 2021 06 29; 35(13):109302. . View in PubMed
  • Comparative study of neuroendocrine acquisition and biomarker expression between neuroendocrine and usual prostatic carcinoma Prostate. 2021 06; 81(8):469-477. . View in PubMed
  • Chronic Aspiration Pneumonitis Caused by Spontaneous Cerebrospinal Fluid Fistulae of the Skull Base Laryngoscope. 2021 03; 131(3):462-466. . View in PubMed
  • Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab037. . View in PubMed
  • Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab005. . View in PubMed
  • Ultra-high field magnetic resonance imaging for localization of corticotropin-secreting pituitary adenomas Neuroradiology. 2020 Aug; 62(8):1051-1054. . View in PubMed
  • Hemorrhagic Presentation of Rathke Cleft Cysts: A Surgical Case Series Oper Neurosurg (Hagerstown). 2020 05 01; 18(5):470-479. . View in PubMed
  • What Genes Can Tell: A Closer Look at Vestibular Schwannoma Otol Neurotol. 2020 04; 41(4):522-529. . View in PubMed
  • Fatal refractory cardiac arrest as presentation of systemic amyloidosis Respir Med Case Rep. 2020; 30:101042. . View in PubMed
  • Surgical management of clinically silent thyrotropin pituitary adenomas: A single center series of 20 patients J Clin Neurosci. 2020 Jan; 71:70-75. . View in PubMed
  • ZBTB16: A new biomarker for primitive neuroectodermal tumor element / Ewing sarcoma Pathol Res Pract. 2019 Oct; 215(10):152536. . View in PubMed
  • Recurrent Rathke’s Cleft Cysts: Incidence and Surgical Management in a Tertiary Pituitary Center over 2 Decades Oper Neurosurg (Hagerstown). 2019 06 01; 16(6):675-684. . View in PubMed
  • Ruptured Mycotic Aneurysm of the Distal Circulation in a Patient with Mucormycosis Without Direct Skull Base Extension: Case Report Oper Neurosurg (Hagerstown). 2019 03 01; 16(3):E101-E107. . View in PubMed
  • Variability and Lack of Prognostic Value Associated With Atypical Pituitary Adenoma Diagnosis: A Systematic Review and Critical Assessment of the Diagnostic Criteria Neurosurgery. 2018 10 01; 83(4):602-610. . View in PubMed
  • Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model J Neurosurg. 2018 03; 128(3):695-700. . View in PubMed
  • Quadruple Neoplasms following Radiation Therapy for Congenital Bilateral Retinoblastoma Ocul Oncol Pathol. 2017 Dec; 4(1):33-37. . View in PubMed
  • Solitary Plasmacytoma in the Internal Auditory Canal and Cerebellopontine Angle Mimicking Meningioma Otol Neurotol. 2016 Dec; 37(10):e400-e401. . View in PubMed
  • “Pistachio” and “Avatar” Green-Blue Discoloration of the Brain Acad Forensic Pathol. 2016 Mar; 6(1):150-152. . View in PubMed
  • Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p133). Cureus. 2015 Jul; 7(7):e289. . View in PubMed
  • Whipple’s disease masquerades as dementia with Lewy bodies Alzheimer Dis Assoc Disord. 2015 Jan-Mar; 29(1):85-89. . View in PubMed
  • A quantitative study of a-synuclein pathology in fifteen cases of dementia associated with Parkinson disease J Neural Transm (Vienna). 2014 Feb; 121(2):171-81. . View in PubMed
  • Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: a case report J Med Case Rep. 2012 Oct 08; 6:341. . View in PubMed
  • Acute presentation of tophaceous myelopathy J Rheumatol. 2011 Jul; 38(7):1525-6. . View in PubMed
  • Bronchial atresia Radiographics. 2009 Sep-Oct; 29(5):1531-5. . View in PubMed
  • Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling Biochemistry. 2004 Feb 24; 43(7):1891-907. . View in PubMed
  • Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate Mol Endocrinol. 2002 Dec; 16(12):2706-19. . View in PubMed
  • Rapid HPLC screening method for contaminants found in implicated L-tryptophan associated with eosinophilia myalgia syndrome and adulterated rapeseed oil associated with toxic oil syndrome Biomed Chromatogr. 1998 Sep-Oct; 12(5):255-61. . View in PubMed

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