Laura A. Kalayjian, MD

Associate Professor of Clinical Neurology, Director, Neurophysiology Lab LAC + USC Medical Center

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Dr. Laura Kalayjian is Chief of Neurology and Director of the EEG Lab at LAC+USC Medical Center. She completed medical school at the University of Massachusetts in Worcester, MA and completed her neurology residency at Stanford University, Palo Alto, CA. She was fellowship trained in epilepsy and neurophysiology under Dr. Martha Morrell at Columbia Presbyterian, New York. She accepted a position at USC in July 2000. She has been active as co-director of the comprehensive epilepsy program and continues to pursue her research interests in women with epilepsy, hormonal influences and pregnancy and quality of life issues in persons with epilepsy.


  • Pasadena Magazine : Top Doctor, 2011


  • Association of Prenatal Exposure to Antiseizure Medications With Creative and Executive Function at Age 45 Years. Neurology. 2024 Jun 25; 102(12):e209448. . View in PubMed
  • Behavioral Outcomes and Neurodevelopmental Disorders Among Children of Women With Epilepsy JAMA Neurol. 2024 Jan 01; 81(1):19-29. . View in PubMed
  • Initiation and Duration of Breastfeeding in the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Study Neurology. 2023 Nov 27; 101(22):e2266-e2276. . View in PubMed
  • Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy Arch Gynecol Obstet. 2023 12; 308(6):1749-1754. . View in PubMed
  • Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study Lancet Neurol. 2023 08; 22(8):712-722. . View in PubMed
  • Effect of Epilepsy on Sleep Quality During Pregnancy and Postpartum Neurology. 2022 Oct 10; 99(15):e1584-e1597. . View in PubMed
  • Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy Nat Neurosci. 2022 04; 25(4):493-503. . View in PubMed
  • Prospective Cohort Study of Depression During Pregnancy and the Postpartum Period in Women With Epilepsy vs Control Groups Neurology. 2022 10 11; 99(15):e1573-e1583. . View in PubMed
  • Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study JAMA Neurol. 2022 04 01; 79(4):370-379. . View in PubMed
  • Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation Epilepsy Res. 2021 01; 169:106532. . View in PubMed
  • Two-Year-Old Cognitive Outcomes in Children of Pregnant Women With Epilepsy in the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Study JAMA Neurol. 2021 08 01; 78(8):927-936. . View in PubMed
  • Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers With Epilepsy JAMA Neurol. 2020 04 01; 77(4):441-450. . View in PubMed
  • Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy N Engl J Med. 2020 12 24; 383(26):2547-2556. . View in PubMed
  • Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy Neurology. 2020 04 07; 94(14):e1502-e1511. . View in PubMed
  • Dual responsive neurostimulation implants for epilepsy J Neurosurg. 2019 Jan 25; 1-7. . View in PubMed
  • Epilepsy Behav. 2019 03; 92:154-164. . View in PubMed
  • Changes in antiepileptic drug-prescribing patterns in pregnant women with epilepsy Epilepsy Behav. 2018 07; 84:10-14. . View in PubMed
  • A Single-Center Experience with the NeuroPace RNS System: A Review of Techniques and Potential Problems World Neurosurg. 2015 Sep; 84(3):719-26. . View in PubMed
  • Valproate and pregnancy: think again Neurology. 2015 Jan 27; 84(4):e25-6. . View in PubMed
  • Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years JAMA Pediatr. 2014 Aug; 168(8):729-36. . View in PubMed
  • Predictive factors of neurological complications and one-month mortality after liver transplantation Front Neurol. 2014; 5:275. . View in PubMed
  • Fetal antiepileptic drug exposure: Adaptive and emotional/behavioral functioning at age 6years Epilepsy Behav. 2013 Nov; 29(2):308-15. . View in PubMed
  • Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study Lancet Neurol. 2013 Mar; 12(3):244-52. . View in PubMed
  • Differential effects of antiepileptic drugs on neonatal outcomes Epilepsy Behav. 2012 Aug; 24(4):449-56. . View in PubMed
  • Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial Neurology. 2012 Jun 12; 78(24):1959-66. . View in PubMed
  • Effects of fetal antiepileptic drug exposure: outcomes at age 45 years. Neurology. 2012 Apr 17; 78(16):1207-14. . View in PubMed
  • Variation of seizure frequency with ovulatory status of menstrual cycles Epilepsia. 2011 Oct; 52(10):1843-8. . View in PubMed
  • Fetal antiepileptic drug exposure: motor, adaptive, and emotional/behavioral functioning at age 3 years Epilepsy Behav. 2011 Oct; 22(2):240-6. . View in PubMed
  • Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors Epilepsy Behav. 2011 Aug; 21(4):391-6. . View in PubMed
  • Relationship of child IQ to parental IQ and education in children with fetal antiepileptic drug exposure Epilepsy Behav. 2011 Jun; 21(2):147-52. . View in PubMed
  • Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age Brain. 2011 Feb; 134(Pt 2):396-404. . View in PubMed
  • Effects of breastfeeding in children of women taking antiepileptic drugs Neurology. 2010 Nov 30; 75(22):1954-60. . View in PubMed
  • Antiepileptic drug use in women of childbearing age Epilepsy Behav. 2009 Jul; 15(3):339-43. . View in PubMed
  • Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs N Engl J Med. 2009 Apr 16; 360(16):1597-605. . View in PubMed
  • In utero antiepileptic drug exposure: fetal death and malformations Neurology. 2006 Aug 08; 67(3):407-12. . View in PubMed
  • Sexual dysfunction, sex steroid hormone abnormalities, and depression in women with epilepsy treated with antiepileptic drugs Epilepsy Behav. 2005 May; 6(3):360-5. . View in PubMed