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Liyun Yuan, MD, PhD

Associate Professor of Clinical Medicine

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Email [email protected]
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Overview

Dr. Yuan is a transplant hepatologist specializing in caring for patients with chronic liver diseases, hepatocellular carcinoma, and pre-/post liver transplantation. She completed her internship and residency training in Internal Medicine at Keck USC School of Medicine, where she further finished gastroenterology fellowship training. After that, she took an extra year advanced training in transplant hepatology at University of Colorado, Denver.

Dr. Yuan’s clinical research interests include Nonalcoholic fatty liver disease, autoimmune hepatitis and outcome of liver transplantation. She has authored several articles in peer-reviewed journals on various topics in liver disease and liver transplantation. Dr. Yuan’s research activities include searching and validating diagnostic markers and prognostic makers in nonalcoholic steatohepatitis, liver targeting of anti-fibrotic therapy, and the role of PGAM5 in hepatic cell death- using the model of acetoaminophen-induced liver injury.

Awards

  • Rho Chi Pharmacy Honor Society: Member, 2004
  • Charles and Charlotte Krown Fellowship, 2005
  • American Association of Pharmaceutical Sciences: Graduate Student Award, 2006

Media

Publications

  • Adipose Tissue Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease. Cells. 2026 Jul 30; 15(15).. View in PubMed
  • Vitamin E dosing study (VEDS) in patients with metabolic dysfunction-associated steatotic liver disease with elevated aminotransferases: A multicenter, randomized, placebo-controlled trial. Hepatology. 2026 Jun 09.. View in PubMed
  • Longitudinal changes in cardiometabolic risk factors are associated with changes in liver stiffness in adults with MASLD. J Hepatol. 2026 Jul; 85(1):37-47.. View in PubMed
  • Association between pattern of hepatic iron deposition and severity of MASH among patients enrolled in the NASH Clinical Research Network. Hepatol Commun. 2025 Dec 01; 9(12).. View in PubMed
  • Differential Effects of Cardiometabolic Risk Factors on All-Cause Mortality in United States Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Clin Gastroenterol Hepatol. 2026 May; 24(5):1344-1353.. View in PubMed
  • Characterizing Kupffer Cell Production of CD5 Antigen-Like and Its Function on Regulating Migration of Natural Killer T Cells. Am J Pathol. 2025 10; 195(10):1839-1853.. View in PubMed
  • Isoform specific regulation of osteopontin by AKT2 in hepatocytes and livers. Cell Signal. 2025 Aug; 132:111799.. View in PubMed
  • Proinflammatory macrophages release CXCL5 to regulate T cell function and limit effects of αPD-1 in steatosis-driven liver cancer. JHEP Rep. 2025 Jun; 7(6):101385.. View in PubMed
  • At the Crossroads of Health and Disease: Consequences of Fat in the Liver. Annu Rev Physiol. 2025 02; 87(1):325-352.. View in PubMed
  • The impact of surging transplantation of alcohol-associated liver disease on transplantation for HCC and other indications. Hepatol Commun. 2024 07 01; 8(7).. View in PubMed

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