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Longwei Liu

Assistant Professor of Ophthalmology and Biomedical Engineering

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Phone +1 213 740 7237
Email [email protected]
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Publications

  • Mechano-regulation of cancer cell memory in tumor progression and therapy. Mechanobiol Med. 2026 Mar; 4(1):100165.. View in PubMed
  • Atlas-guided discovery of transcription factors for T cell programming. Nature. 2026 Feb 04.. View in PubMed
  • Tumour priming by ultrasound mechanogenetics for CAR T therapy. Nat Mater. 2026 Feb; 25(2):310-321.. View in PubMed
  • Atlas-Guided Discovery of Transcription Factors for T Cell Programming. bioRxiv. 2025 Nov 02.. View in PubMed
  • Severing the scar supply line: CAR-T in chronic kidney disease. Cell Stem Cell. 2025 Sep 04; 32(9):1309-1310.. View in PubMed
  • Sound activated immune cells. Immunotherapy. 2025 Sep; 17(13):899-901.. View in PubMed
  • EchoBack-CAR T cells: Tuning immunity with sound. Clin Transl Med. 2025 Jul; 15(7):e70391.. View in PubMed
  • Engineering sonogenetic EchoBack-CAR T cells. Cell. 2025 May 15; 188(10):2621-2636.e20.. View in PubMed
  • Far-red chemigenetic kinase biosensors enable multiplexed and super-resolved imaging of signaling networks. Nat Biotechnol. 2025 Apr 21.. View in PubMed
  • Nutrient-driven histone code determines exhausted CD8+ T cell fates. Science. 2025 Feb 07; 387(6734):eadj3020.. View in PubMed
  • Frontiers in mechanobiology and mechanomedicine. Med X. 2025; 3(1):23.. View in PubMed
  • Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy. Nat Commun. 2024 12 01; 15(1):10444.. View in PubMed
  • Light-gated integrator for highlighting kinase activity in living cells. Nat Commun. 2024 09 06; 15(1):7804.. View in PubMed
  • Heat-inducible CAR-T overcomes adverse mechanical tumor microenvironment in a 3D bioprinted glioblastoma model. Mater Today Bio. 2024 Jun; 26:101077.. View in PubMed
  • Integration of 3D bioprinting and multi-algorithm machine learning identified glioma susceptibilities and microenvironment characteristics. Cell Discov. 2024 Apr 09; 10(1):39.. View in PubMed
  • Light-gated Integrator for Highlighting Kinase Activity in Living Cells. bioRxiv. 2024 Mar 20.. View in PubMed
  • Engineering a Programmed Death-Ligand 1-Targeting Monobody Via Directed Evolution for SynNotch-Gated Cell Therapy. ACS Nano. 2024 03 19; 18(11):8531-8545.. View in PubMed
  • Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging. bioRxiv. 2024 Feb 11.. View in PubMed
  • Cellular and molecular imaging of CAR-T cell-based immunotherapy. Adv Drug Deliv Rev. 2023 12; 203:115135.. View in PubMed
  • LUNAS: A Rapid and Sensitive Nucleic Acid Detection Assay Using Split NanoLuc Luciferase Complementation. ACS Cent Sci. 2023 Apr 26; 9(4):593-596.. View in PubMed
  • Balancing activation and co-stimulation of CAR tunes signaling dynamics and enhances therapeutic potency. Mol Ther. 2023 01 04; 31(1):35-47.. View in PubMed
  • Engineering chimeric antigen receptor T cells for solid tumour therapy. Clin Transl Med. 2022 12; 12(12):e1141.. View in PubMed
  • Transient nuclear deformation primes epigenetic state and promotes cell reprogramming. Nat Mater. 2022 10; 21(10):1191-1199.. View in PubMed
  • Mechanosensor Piezo1 mediates bimodal patterns of intracellular calcium and FAK signaling. EMBO J. 2022 09 01; 41(17):e111799.. View in PubMed
  • Occurrence of Bensulfuron-Methyl Resistance and Target-Site Resistance Mechanisms in Ammannia auriculata Biotypes from Paddy Fields. Plants (Basel). 2022 Jul 25; 11(15).. View in PubMed
  • Engineering CAR T cells for enhanced efficacy and safety. APL Bioeng. 2022 Mar; 6(1):011502.. View in PubMed
  • Tracking the Dynamic Histone Methylation of H3K27 in Live Cancer Cells. ACS Sens. 2021 12 24; 6(12):4369-4378.. View in PubMed
  • Integration of FRET and sequencing to engineer kinase biosensors from mammalian cell libraries. Nat Commun. 2021 08 19; 12(1):5031.. View in PubMed
  • Asporin inhibits collagen matrix-mediated intercellular mechanocommunications between fibroblasts during keloid progression. FASEB J. 2021 07; 35(7):e21705.. View in PubMed
  • Engineering 3D functional tissue constructs using self-assembling cell-laden microniches. Acta Biomater. 2020 09 15; 114:170-182.. View in PubMed
  • Matrix-transmitted paratensile signaling enables myofibroblast-fibroblast cross talk in fibrosis expansion. Proc Natl Acad Sci U S A. 2020 05 19; 117(20):10832-10838.. View in PubMed
  • Application of FRET Biosensors in Mechanobiology and Mechanopharmacological Screening. Front Bioeng Biotechnol. 2020; 8:595497.. View in PubMed
  • Managing keloid scars: From radiation therapy to actual and potential drug deliveries. Int Wound J. 2019 Jun; 16(3):852-859.. View in PubMed
  • Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis. Nat Mater. 2017 12; 16(12):1252-1261.. View in PubMed
  • Keloid progression: a stiffness gap hypothesis. Int Wound J. 2017 Oct; 14(5):764-771.. View in PubMed
  • Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy. Biomaterials. 2017 04; 124:12-24.. View in PubMed
  • Substrate stiffness orchestrates epithelial cellular heterogeneity with controlled proliferative pattern via E-cadherin/β-catenin mechanotransduction. Acta Biomater. 2016 09 01; 41:169-80.. View in PubMed
  • Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation. Biomaterials. 2016 Jun; 91:11-22.. View in PubMed

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