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Manju Aron, MD

Professor of Clinical Pathology and Urology

GU Service Line Director

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Phone +1 323 409 4614
Email [email protected]
CTSI Profile

Publications

  • The Dublin International Society of Urological Pathology (ISUP) Consensus Conference on Best Practice Recommendations on the Pathology of Glandular Lesions of the Urinary Bladder. Adv Anat Pathol. 2026 Jan 01; 33(1):1-16.. View in PubMed
  • Genitourinary Pathology Society and International Society of Urological Pathology White Paper on Defining Indolent Prostate Cancer. Am J Surg Pathol. 2025 Dec 01; 49(12):e27-e32.. View in PubMed
  • Interobserver Reproducibility of Pelvicalyceal Invasion in Renal Cell Carcinoma Nephrectomies Among Genitourinary Pathologists. Am J Surg Pathol. 2025 Dec 01; 49(12):1307-1314.. View in PubMed
  • Re: Baris Turkbey, Henkjan Huisman, Andriy Fedorov, et al. Requirements for AI Development and Reporting for MRI Prostate Cancer Detection in Biopsy-Naïve Men: PI-RADS Steering Committee, Version 1.0. Radiology 2025;315:e24014. Eur Urol. 2025 Nov; 88(5):e101-e102.. View in PubMed
  • The Dublin International Society of Urological Pathology (ISUP) Consensus Conference on Best Practice Recommendations on the Pathology of Urachal Neoplasms. Am J Surg Pathol. 2025 Nov 01; 49(11):e18-e26.. View in PubMed
  • Current practices in prostate pathology reporting: results from a survey of genitourinary and general pathologists. Histopathology. 2025 Aug; 87(2):206-222.. View in PubMed
  • Impact of magnetic resonance imaging visibility of prostate cancer on partial gland ablation. BJUI Compass. 2025 Aug; 6(8):e70065.. View in PubMed
  • Genitourinary Pathology Society and International Society of Urological Pathology White Paper on Defining Indolent Prostate Cancer: Call for a Multidisciplinary Approach. Eur Urol. 2025 Jul; 88(1):8-10.. View in PubMed
  • Prediction of PD-L1 and CD68 in Clear Cell Renal Cell Carcinoma with Green Learning. J Imaging. 2025 Jun 10; 11(6).. View in PubMed
  • Mucinous Borderline Tumors of the Pelvicalyceal System: Report of Two Tumors With Molecular Findings and Review of Literature. Int J Surg Pathol. 2025 Jun; 33(4):1022-1028.. View in PubMed
  • The outcomes of salvage robotic radical prostatectomy following radiation versus focal therapy: Does the primary treatment modality matter? BJUI Compass. 2025 May; 6(5):e70019.. View in PubMed
  • Renal Juxtaglomerular Cell Tumors Exhibit Distinct Genomic and Epigenomic Features and Lack Recurrent Gene Fusions: Comprehensive Molecular Analysis of a Multi-institutional Series. Am J Surg Pathol. 2025 Mar 01; 49(3):217-226.. View in PubMed
  • SS18-SSX Expression and Clinicopathologic Profiles in a Contemporary Cohort of Primary Paratesticular Synovial Sarcoma: A Series of Fourteen Patients. Am J Surg Pathol. 2025 Jan 01; 49(1):11-19.. View in PubMed
  • The learning curve for transperineal MRI/TRUS fusion prostate biopsy: A prospective evaluation of a stepwise approach. Urol Oncol. 2025 01; 43(1):64.e1-64.e10.. View in PubMed
  • A sustainable and expedited ‘One-Stop’ prostate cancer diagnostic pathway to reduce environmental impact and enhance accessibility. BJUI Compass. 2024 Dec; 5(12):1278-1287.. View in PubMed
  • Advances, recognition, and interpretation of molecular heterogeneity among conventional and subtype histology of urothelial carcinoma (UC): a survey among urologic pathologists and comprehensive review of the literature. Histopathology. 2024 Nov; 85(5):748-759.. View in PubMed
  • Acceptance of emerging renal oncocytic neoplasms: a survey of urologic pathologists. Virchows Arch. 2024 Nov; 485(5):829-840.. View in PubMed
  • Transperineal versus Transrectal MRI/TRUS fusion-guided prostate biopsy in a large, ethnically diverse, and multiracial cohort. Int Braz J Urol. 2024 Sep-Oct; 50(5):616-628.. View in PubMed
  • Prostatic adenocarcinoma: molecular underpinnings and treatment-related options. Urol Oncol. 2024 07; 42(7):203-210.. View in PubMed
  • Molecular Characterization of Juxtaglomerular Cell Tumors: Evidence of Alterations in MAPK-RAS Pathway. Mod Pathol. 2024 Jun; 37(6):100492.. View in PubMed
  • A nomogram to predict the absence of clinically significant prostate cancer in males with negative MRI Int Braz J Urol. 2024 May-Jun; 50(3):319-334.. View in PubMed
  • Patterns of Immunoreactivity with TTF-1 Antibodies 8G7G3/1 and SPT24 Suggest Distinct Immunoprofiles Between Most Pulmonary and Nonpulmonary Small Cell Carcinomas. Int J Surg Pathol. 2024 Apr; 32(2):230-238.. View in PubMed
  • Urinary Bladder “Melanosis”: A Case Report and Review of the Literature. Int J Surg Pathol. 2024 Feb; 32(1):104-108.. View in PubMed
  • Radiomics Correlation to CD68+ Tumor-Associated Macrophages in Clear Cell Renal Cell Carcinoma. Oncology. 2024; 102(3):260-270.. View in PubMed
  • Nested and Large Nested Subtypes of Urothelial Carcinoma of the Upper Urinary Tract: A Multi-institutional Study. Mod Pathol. 2023 12; 36(12):100333.. View in PubMed
  • Perioperative Complications and Oncologic Outcomes of Nephrectomy Following Immune Checkpoint Inhibitor Therapy: A Multicenter Collaborative Study. Eur Urol Oncol. 2023 12; 6(6):604-610.. View in PubMed
  • Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration. Hum Pathol. 2023 09; 139:37-46.. View in PubMed
  • Reporting Trends, Practices, and Resource Utilization in Neuroendocrine Tumors of the Prostate Gland: A Survey among Thirty-Nine Genitourinary Pathologists. Int J Surg Pathol. 2023 Sep; 31(6):993-1005.. View in PubMed
  • Transperineal vs transrectal magnetic resonance and ultrasound image fusion prostate biopsy: a pair-matched comparison. Sci Rep. 2023 08 18; 13(1):13457.. View in PubMed
  • Metastatic solid tumours to the penis: a clinicopathologic evaluation of 109 cases from an international collaboration. Histopathology. 2023 Jul; 83(1):31-39.. View in PubMed
  • Urine Cytology Findings in Cases of Pseudocarcinomatous Urothelial Hyperplasia of the Bladder Often Represent a Diagnostic Challenge. Arch Pathol Lab Med. 2023 06 01; 147(6):716-721.. View in PubMed
  • Transperineal magnetic resonance imaging/transrectal ultrasonography fusion prostate biopsy under local anaesthesia: the ‘double-freehand’ technique. BJU Int. 2023 06; 131(6):770-774.. View in PubMed
  • Reprint of: Female Urethral Carcinoma: A contemporary review of the clinicopathologic features, with emphasis on the histo-anatomic landmarks and potential staging issues. Hum Pathol. 2023 03; 133:126-135.. View in PubMed
  • Feminizing Adrenocortical Tumor with Multiple Recurrences: A Case Report. Case Rep Oncol. 2023 Jan-Dec; 16(1):1033-1040.. View in PubMed
  • Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study. Oncology. 2023; 101(6):375-388.. View in PubMed
  • Localized Multifocal Retroperitoneal Ganglioneuroma with an Infiltrative Appearance on Imaging: A Case Report. Case Rep Oncol. 2023 Jan-Dec; 16(1):1142-1147.. View in PubMed
  • Ensuring remote diagnostics for pathologists: an open letter to the US Congress. Nat Med. 2022 12; 28(12):2453-2455.. View in PubMed
  • Urothelial Carcinoma: Update on Staging and Reporting, and Pathologic Changes Following Neoadjuvant Chemotherapies. Surg Pathol Clin. 2022 Dec; 15(4):661-679.. View in PubMed
  • Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues. Hum Pathol. 2022 11; 129:71-80.. View in PubMed
  • Prostatic malakoplakia: clinicopathological assessment of a multi-institutional series of 49 patients. Histopathology. 2022 Oct; 81(4):520-528.. View in PubMed
  • Machine Learning to Delineate Surgeon and Clinical Factors That Anticipate Positive Surgical Margins After Robot-Assisted Radical Prostatectomy. J Endourol. 2022 09; 36(9):1192-1198.. View in PubMed
  • The safety, tolerability, and efficacy of a neoadjuvant gemcitabine intravesical drug delivery system (TAR-200) in muscle-invasive bladder cancer patients: a phase I trial. Urol Oncol. 2022 07; 40(7):344.e1-344.e9.. View in PubMed
  • Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 new tumors in 59 patients. Mod Pathol. 2022 06; 35(6):836-849.. View in PubMed
  • CT-based radiomics stratification of tumor grade and TNM stage of clear cell renal cell carcinoma. Eur Radiol. 2022 Apr; 32(4):2552-2563.. View in PubMed
  • Testicular Germ-Cell Tumors with Spermatic Cord Involvement: A Retrospective International Multi-Institutional Experience. Mod Pathol. 2022 02; 35(2):249-255.. View in PubMed
  • Can We Avoid a Systematic Biopsy in Men with PI-RADS® 5? Reply. J Urol. 2022 01; 207(1):241-242.. View in PubMed
  • Feasibility of using CT radiomic signatures for predicting CD8-T cell infiltration and PD-L1 expression in renal cell carcinoma. Eur J Radiol Open. 2022; 9:100440.. View in PubMed
  • Prognostic value of cribriform size, percentage, and intraductal carcinoma in Gleason score 7 prostate cancer with cribriform Gleason pattern 4. Hum Pathol. 2021 12; 118:18-29.. View in PubMed
  • MRI predicts prostatic urethral involvement in men undergoing radical prostatectomy: implications for cryo-ablation of localized prostate cancer. World J Urol. 2021 Sep; 39(9):3309-3314.. View in PubMed
  • Role of Ki-67, MRE11, and PD-L1 as Predictive Biomarkers for Recurrence Pattern in Muscle-invasive Bladder Cancer. Anticancer Res. 2021 Aug; 41(8):3851-3857.. View in PubMed
  • Reply by Authors. J Urol. 2021 08; 206(2):297.. View in PubMed
  • Reply by Authors. J Urol. 2021 08; 206(2):426.. View in PubMed
  • Systematic Biopsy of the Prostate can Be Omitted in Men with PI-RADS™ 5 and Prostate Specific Antigen Density Greater than 15. J Urol. 2021 08; 206(2):289-297.. View in PubMed
  • Multiparametric magnetic resonance imaging facilitates reclassification during active surveillance for prostate cancer. BJU Int. 2021 06; 127(6):712-721.. View in PubMed
  • Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey. Urol Oncol. 2021 05; 39(5):295.e1-295.e8.. View in PubMed
  • The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer. Arch Pathol Lab Med. 2021 04 01; 145(4):461-493.. View in PubMed
  • Shape and texture-based radiomics signature on CT effectively discriminates benign from malignant renal masses. Eur Radiol. 2021 Feb; 31(2):1011-1021.. View in PubMed
  • Diagnosis of “cribriform” prostatic adenocarcinoma: an interobserver reproducibility study among urologic pathologists with recommendations. Am J Cancer Res. 2021; 11(8):3990-4001.. View in PubMed
  • Similarities and Differences in the 2019 ISUP and GUPS Recommendations on Prostate Cancer Grading: A Guide for Practicing Pathologists. Adv Anat Pathol. 2021 Jan; 28(1):1-7.. View in PubMed
  • Primary Female Urethral Carcinoma: Proposed Staging Modifications Based on Assessment of Female Urethral Histology and Analysis of a Large Series of Female Urethral Carcinomas. Am J Surg Pathol. 2020 12; 44(12):1591-1601.. View in PubMed
  • High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series. J Urol. 2020 10; 204(4):741-747.. View in PubMed
  • Perioperative Outcome of Suprarenal Resection of Vena Cava Without Reconstruction in Urologic Malignancies: A Case Series and Review of the Literature. Urology. 2020 08; 142:146-154.. View in PubMed
  • Deep learning based classification of solid lipid-poor contrast enhancing renal masses using contrast enhanced CT. Br J Radiol. 2020 Jul; 93(1111):20200002.. View in PubMed
  • Reporting Practices and Resource Utilization in the Era of Intraductal Carcinoma of the Prostate: A Survey of Genitourinary Subspecialists. Am J Surg Pathol. 2020 05; 44(5):673-680.. View in PubMed
  • One-Stop MRI and MRI/transrectal ultrasound fusion-guided biopsy: an expedited pathway for prostate cancer diagnosis. World J Urol. 2020 Apr; 38(4):949-956.. View in PubMed
  • Juxtaglomerular Cell Tumor With Atypical Pathological Features: Report of a Case and Review of Literature. Int J Surg Pathol. 2020 Feb; 28(1):87-91.. View in PubMed
  • Variant Histology in Bladder Cancer-Current Understanding of Pathologic Subtypes. Curr Urol Rep. 2019 Nov 28; 20(12):80.. View in PubMed
  • Step-by-Step: Fusion-guided prostate biopsy in the diagnosis and surveillance of prostate cancer. Int Braz J Urol. 2019 Nov-Dec; 45(6):1277-1278.. View in PubMed
  • Juxtatumoral perinephric fat analysis in clear cell renal cell carcinoma. Abdom Radiol (NY). 2019 04; 44(4):1470-1480.. View in PubMed
  • Diffuse Large B-Cell Lymphoma With Striking Intrasinusoidal Pseudoglandular Growth Pattern as a Diagnostic Dilemma Mimicking Metastatic Poorly Differentiated Pancreatic Adenocarcinoma in an Intraabdominal Lymph Node. Int J Surg Pathol. 2019 Apr; 27(2):181-184.. View in PubMed
  • Utility of rapid on-site evaluation for needle core biopsies and fine-needle aspiration cytology done for diagnosis of mass lesions of the liver. J Am Soc Cytopathol. 2019 Mar – Apr; 8(2):69-77.. View in PubMed
  • Contrast-Enhanced Transrectal Ultrasound for Follow-up After Focal HIFU Ablation for Prostate Cancer. J Ultrasound Med. 2019 Mar; 38(3):811-819.. View in PubMed
  • Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images. Sci Rep. 2019 02 07; 9(1):1570.. View in PubMed
  • Which Patients with Negative Magnetic Resonance Imaging Can Safely Avoid Biopsy for Prostate Cancer? J Urol. 2019 02; 201(2):268-276.. View in PubMed
  • Histological Validation of 11Carbon-Acetate Positron Emission Tomography/Computerized Tomography in Detecting Lymph Node Metastases in Prostate Cancer. J Urol. 2019 02; 201(2):332-341.. View in PubMed
  • Computed tomography-based texture analysis of bladder cancer: differentiating urothelial carcinoma from micropapillary carcinoma. Abdom Radiol (NY). 2019 01; 44(1):201-208.. View in PubMed
  • Contrast-Enhanced Ultrasound of Spermatic Cord and Retroperitoneal Liposarcoma. Ultrasound Q. 2018 Dec; 34(4):292-296.. View in PubMed
  • A Decision-Support Tool for Renal Mass Classification. J Digit Imaging. 2018 12; 31(6):929-939.. View in PubMed
  • Quantitative Contour Analysis as an Image-based Discriminator Between Benign and Malignant Renal Tumors. Urology. 2018 Apr; 114:121-127.. View in PubMed
  • ZBTB16 is a sensitive and specific marker in detection of metastatic and extragonadal yolk sac tumour. Histopathology. 2017 Oct; 71(4):562-569.. View in PubMed
  • Voxel-based whole-lesion enhancement parameters: a study of its clinical value in differentiating clear cell renal cell carcinoma from renal oncocytoma. Abdom Radiol (NY). 2017 02; 42(2):552-560.. View in PubMed
  • Improving needle biopsy accuracy in small renal mass using tumor-specific DNA methylation markers. Oncotarget. 2017 Jan 17; 8(3):5439-5448.. View in PubMed
  • Identifying aggressive prostate cancer foci using a DNA methylation classifier. Genome Biol. 2017 01 12; 18(1):3.. View in PubMed
  • Mechanical Implantation of Urothelium Into Periureteral Soft Tissue: A Series of 4 Cases Mimicking High-stage Urothelial Carcinoma. Am J Surg Pathol. 2016 11; 40(11):1564-1570.. View in PubMed
  • Utility and significance of ureteric frozen section analysis during radical cystectomy. BJU Int. 2016 Mar; 117(3):463-8.. View in PubMed
  • Trans-rectal ultrasound visibility of prostate lesions identified by magnetic resonance imaging increases accuracy of image-fusion targeted biopsies. World J Urol. 2015 Nov; 33(11):1669-76.. View in PubMed
  • Prostate Cancer Volume Estimation by Combining Magnetic Resonance Imaging and Targeted Biopsy Proven Cancer Core Length: Correlation with Cancer Volume. J Urol. 2015 Oct; 194(4):957-65.. View in PubMed
  • Contrast-enhanced ultrasound findings of post-transplant lymphoproliferative disorder in a transplanted kidney: A case report and literature review. J Radiol Case Rep. 2015 Oct; 9(10):26-34.. View in PubMed
  • Clear cell-papillary renal cell carcinoma of the kidney not associated with end-stage renal disease: clinicopathologic correlation with expanded immunophenotypic and molecular characterization of a large cohort with emphasis on relationship with renal angiomyoadenomatous tumor. Am J Surg Pathol. 2015 Jul; 39(7):873-88.. View in PubMed
  • A novel technique using three-dimensionally documented biopsy mapping allows precise re-visiting of prostate cancer foci with serial surveillance of cell cycle progression gene panel. Prostate. 2015 Jun; 75(8):863-71.. View in PubMed
  • Magnetic resonance imaging-transectal ultrasound image-fusion biopsies accurately characterize the index tumor: correlation with step-sectioned radical prostatectomy specimens in 135 patients. Eur Urol. 2015 Apr; 67(4):787-94.. View in PubMed
  • Renal leiomyoma: a contemporary multi-institution study of an infrequent and frequently misclassified neoplasm. Am J Surg Pathol. 2015 Mar; 39(3):349-56.. View in PubMed
  • Robot-assisted bladder diverticulectomy. J Endourol. 2014 Oct; 28(10):1159-64.. View in PubMed
  • Evaluation of contemporary prostate and urothelial lineage biomarkers in a consecutive cohort of poorly differentiated bladder neck carcinomas. Am J Clin Pathol. 2014 Aug; 142(2):173-83.. View in PubMed
  • Immunohistochemical evaluation of novel and traditional markers associated with urothelial differentiation in a spectrum of variants of urothelial carcinoma of the urinary bladder. Hum Pathol. 2014 Jul; 45(7):1473-82.. View in PubMed
  • Utility of a triple antibody cocktail intraurothelial neoplasm-3 (IUN-3-CK20/CD44s/p53) and α-methylacyl-CoA racemase (AMACR) in the distinction of urothelial carcinoma in situ (CIS) and reactive urothelial atypia. Am J Surg Pathol. 2013 Dec; 37(12):1815-23.. View in PubMed
  • Non-epithelial neoplasms of the prostate. Histopathology. 2012 Jan; 60(1):166-86.. View in PubMed
  • Merkel cell carcinoma of the genitourinary tract. Arch Pathol Lab Med. 2011 Aug; 135(8):1067-71.. View in PubMed
  • Renal cell carcinomas with intratumoral fat and concomitant angiomyolipoma: potential pitfalls in staging and diagnosis. Am J Clin Pathol. 2010 Nov; 134(5):807-12.. View in PubMed
  • Fine needle aspiration cytology of follicular variant of papillary carcinoma of the thyroid: Morphologic pointers to its diagnosis. Acta Cytol. 2006 Nov-Dec; 50(6):663-8.. View in PubMed
  • Utility of galectin 3 expression in thyroid aspirates as a diagnostic marker in differentiating benign from malignant thyroid neoplasms. Indian J Pathol Microbiol. 2006 Jul; 49(3):376-80.. View in PubMed
  • Role of fine-needle aspiration cytology in the diagnosis of secondary tumors of the thyroid–twenty years’ experience. Diagn Cytopathol. 2006 Mar; 34(3):240-5.. View in PubMed
  • Role of testicular fine-needle aspiration cytology in infertile men with clinically obstructive azoospermia. Natl Med J India. 2006 Jan-Feb; 19(1):18-20.. View in PubMed
  • Fine-needle aspiration cytology of glycogen-rich carcinoma of breast: report of a case and review of literature. Diagn Cytopathol. 2005 Oct; 33(4):263-7.. View in PubMed
  • Rapid staining using toluidine blue: a reliable method for quick diagnosis in ultrasound-guided aspiration cytology. Indian J Pathol Microbiol. 2003 Oct; 46(4):589-92.. View in PubMed
  • Primary primitive neuroectodermal tumor (PNET) of the kidney with venous thrombus. Int Urol Nephrol. 2003; 35(3):311-2.. View in PubMed

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