Keck School Faculty

Mark Lee Barr, MD
Mark Lee Barr, MD
Associate Professor of Surgery
1520 San Pablo St. Health Sciences Campus Los Angeles
Dr. Mark L. Barr obtained his medical degree from Mount Sinai School of Medicine in New York and completed 10 years of postgraduate residency at New York University and Columbia University, including a 2-year NIH-sponsored research fellowship in transplantation immunology. Dr. Barr is former President and current Chair of the Scientific Grants and Awards Committee of the International Society for Heart and Lung Transplantation (ISHLT) and is the Immediate Past Chair of the Thoracic Committee of the American Society of Transplant Surgeons (ASTS). He has served on the Board of Directors of both the ASTS and the American Society of Transplantation, and as the Program Chair for the Annual Scientific Meeting of Both the ISHLT and the American Transplant Congress. Dr. Barr actively serves on multiple governmental transplant-related oversight subcommittees under the auspices of the Health Resources and Services Administration (HRSA) of the US Department of Health and Human Services (DHHS), including the Scientific Technical Advisory Committee of the Scientific Registry of Transplant Recipients. He is the incoming Chair of the Thoracic Committee for the United Network of Organ Sharing (UNOS). Dr. Barr has authored more than 150 peer-reviewed publications and book chapters in the fields of cardiothoracic surgery and heart and lung transplantation. He is a Deputy Editor of the American Journal of Transplantation. In addition, Dr. Barr is a standing reviewer for the Annals of Thoracic Surgery, the Journal of Heart and Lung Transplantation, the Journal of Thoracic and Cardiovascular Surgery, Lancet, and Transplantation. He maintains an active research program, funded by both federal and regional grant support, studying transplant immunology and Pulmonary physiology. He has served as a study section member for the NIAID, NHLBI, and NCRR of the National Institutes of Health.

Invited Commentary Ann Thorac Surg. 2018 Apr; 105(4):1157-1159. . View in PubMed

Selective Aortic Arch and Root Replacement in Repair of Acute Type A Aortic Dissection Ann Thorac Surg. 2018 Feb; 105(2):505-512. . View in PubMed

Outcomes after mitral valve repair: A single-center 16-year experienceJ Thorac Cardiovasc Surg. 2017 Sep; 154(3):822-830. e2. . View in PubMed

Assessment of segmental myocardial blood flow and myocardial perfusion reserve by adenosine-stress myocardial arterial spin labeling perfusion imaging J Magn Reson Imaging. 2017 Aug; 46(2):413-420. . View in PubMed

The Utility of Nurse-Managed Extracorporeal Life Support in an Adult Cardiac Intensive Care Unit Ann Thorac Surg. 2017 Aug; 104(2):510-514. . View in PubMed

Assessment of segmental myocardial blood flow and myocardial perfusion reserve by adenosine-stress myocardial arterial spin labeling perfusion imaging J Magn Reson Imaging. 2017 08; 46(2):413-420. . View in PubMed

Double-gated myocardial ASL perfusion imaging is robust to heart rate variation Magn Reson Med. 2017 05; 77(5):1975-1980. . View in PubMed

A comparison of aortic valve replacement via an anterior right minithoracotomy with standard sternotomy: a propensity score analysis of 492 patients Eur J Cardiothorac Surg. 2016 Feb; 49(2):456-63. . View in PubMed

Outcomes after pregnancy in living lobar lung transplantation Transplantation. 2014 Oct 15; 98(7):692-4. . View in PubMed

Oscillatory shear stress induces mitochondrial superoxide production: implication of NADPH oxidase and c-Jun NH2-terminal kinase signaling Antioxid Redox Signal. 2011 Sep 01; 15(5):1379-88. . View in PubMed

Electrochemical impedance spectroscopy to assess vascular oxidative stress Ann Biomed Eng. 2011 Jan; 39(1):287-96. . View in PubMed

Lung transplantation for cystic fibrosis Proc Am Thorac Soc. 2009 Dec; 6(8):619-33. . View in PubMed

CT-guided tube pericardiostomy: a safe and effective technique in the management of postsurgical pericardial effusion AJR Am J Roentgenol. 2009 Oct; 193(4):W314-20. . View in PubMed

Genetic modulation of CD44 expression by intragraft fibroblasts J Biochem. 2008 Nov; 144(5):571-80. . View in PubMed

Outcomes after lung retransplantation in the modern era Am J Respir Crit Care Med. 2008 Jan 01; 177(1):114-20. . View in PubMed

Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration Free Radic Biol Med. 2007 Feb 15; 42(4):519-29. . View in PubMed

Rat chemokine CXCL11: structure, tissue distribution, function and expression in cardiac transplantation models Mol Cell Biochem. 2007 Feb; 296(1-2):1-9. . View in PubMed

Multicenter retrospective analysis of cardiovascular risk factors affecting long-term outcome of de novo cardiac transplant recipients J Heart Lung Transplant. 2006 Sep; 25(9):1063-9. . View in PubMed

A report of the Vancouver Forum on the care of the live organ donor: lung, liver, pancreas, and intestine data and medical guidelines Transplantation. 2006 May 27; 81(10):1373-85. . View in PubMed

The role of the hyaluronan receptor CD44 in mesenchymal stem cell migration in the extracellular matrix Stem Cells. 2006 Apr; 24(4):928-35. . View in PubMed

Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient Int Immunol. 2006 Feb; 18(2):279-89. . View in PubMed

Transforming growth factor-beta/interleukin-2-induced regulatory CD4+ T cells prolong cardiac allograft survival in rats J Heart Lung Transplant. 2005 Dec; 24(12):2153-9. . View in PubMed

Pleural space problems after living lobar transplantation J Heart Lung Transplant. 2005 Dec; 24(12):2086-90. . View in PubMed

Contribution of mesenchymal progenitor cells to tissue repair in rat cardiac allografts undergoing chronic rejection J Heart Lung Transplant. 2005 Dec; 24(12):2160-9. . View in PubMed

Living donor lobar lung transplantation: current status and future directions Transplant Proc. 2005 Nov; 37(9):3983-6. . View in PubMed

The ethics of living donor lung transplantation Thorac Surg Clin. 2005 Nov; 15(4):519-25. . View in PubMed

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part IV: recipient-related risk factors and markers J Heart Lung Transplant. 2005 Oct; 24(10):1468-82. . View in PubMed

Thoracic organ transplantation in the United States, 1994-2003 Am J Transplant. 2005 Apr; 5(4 Pt 2):934-49. . View in PubMed

Long-term pulmonary function after living-donor lobar lung transplantation in adults Ann Thorac Surg. 2005 Feb; 79(2):418-25. . View in PubMed

Living lobar lung transplantation Respir Care Clin N Am. 2004 Dec; 10(4):563-79. . View in PubMed

A decade of living lobar lung transplantation: perioperative complications after 253 donor lobectomies Am J Transplant. 2004 Aug; 4(8):1283-8. . View in PubMed

Surrogate markers and risk factors for chronic lung allograft dysfunction Am J Transplant. 2004 Jul; 4(7):1171-8. . View in PubMed

Neochordal repair of the posterior mitral leaflet J Thorac Cardiovasc Surg. 2004 Feb; 127(2):440-7. . View in PubMed

A decade of living lobar lung transplantation: recipient outcomes J Thorac Cardiovasc Surg. 2004 Jan; 127(1):114-22. . View in PubMed

Potential role for antiangiogenic proteins in the myocardial infarction repair process J Surg Res. 2004 Jan; 116(1):156-64. . View in PubMed

Thoracic organ transplantation Am J Transplant. 2004; 4 Suppl 9:93-105. . View in PubMed

Determinants of quality of life changes among long-term cardiac transplant survivors: results from longitudinal data J Heart Lung Transplant. 2003 Oct; 22(10):1157-67. . View in PubMed

Evidence for recipient derived fibroblast recruitment and activation during the development of chronic cardiac allograft rejection Transplantation. 2003 Aug 15; 76(3):609-14. . View in PubMed

Depopulated vena caval homograft: a new venous conduit J Thorac Cardiovasc Surg. 2003 Aug; 126(2):498-503. . View in PubMed

Living lobar transplantation Chest Surg Clin N Am. 2003 Aug; 13(3):505-24. . View in PubMed

Photopheresis for the prevention and treatment of transplant rejection J Cutan Med Surg. 2003 Jul-Aug; 7(4 Suppl):18-9. . View in PubMed

The PORTEL registry: overview and selected findings Prog Transplant. 2003 Jun; Suppl:3-13; quiz 16-7. . View in PubMed

Migration of mesenchymal stem cells to heart allografts during chronic rejection Transplantation. 2003 Mar 15; 75(5):679-85. . View in PubMed

Thoracic transplantation Am J Transplant. 2003; 3 Suppl 4:91-102. . View in PubMed

Does lung growth occur when mature lobes are transplanted into children? Pediatr Transplant. 2002 Dec; 6(6):500-4.. View in PubMed

Hyperinflation resulting in hemodynamic collapse following living donor lobar transplantation Anesthesiology. 2002 Nov; 97(5):1315-7. . View in PubMed

Vascular endothelial cell apoptosis induced by anti-donor non-MHC antibodies: a possible injury pathway contributing to chronic allograft rejection J Heart Lung Transplant. 2002 Nov; 21(11):1174-87. . View in PubMed

Life satisfaction and adverse effects in renal transplant recipients: a longitudinal analysis Clin Transplant. 2002 Apr; 16(2):113-21. . View in PubMed

Dyspnea lusoria: compression of the pulmonary artery by a Kommerell's diverticulum Ann Thorac Surg. 2002 Jan; 73(1):312-3. . View in PubMed

Prophylactic photopheresis and chronic rejection: effects on graft intimal hyperplasia in cardiac transplantation Clin Transplant. 2000 Apr; 14(2):162-6. . View in PubMed

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