Michael Anthony Bonaguidi, PhD

Associate Professor of Stem Cell & Regenerative Medicine and Gerontology

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Overview

Bonaguidi Lab Website

Research Funding

  • Neural stem cell rejuvenation through single cell pharmacogenomics
    NIH · R01AG076956 · Jun 15, 2022 – Feb 28, 2027 · Role: Principal Investigator
  • Mechanisms Underlying Adult Neural Stem Cell Homeostasis
    NIH · R56AG064077 · Sep 15, 2019 – Aug 31, 2021 · Role: Principal Investigator
  • Mechanisms Underlying Neural Stem Cell Heterogeneity in the Adult Hippocampus
    NIH · R00NS080913 · Jun 15, 2015 – Mar 31, 2019 · Role: Principal Investigator
  • Mechanisms Underlying Neural Stem Cell Heterogeneity in the Adult Hippocampus
    NIH · K99NS080913 · Sep 30, 2012 – Dec 31, 2014 · Role: Principal Investigator

Publications

  • New functions for adult neurogenesis in humans: Guideposts for regenerative medicine. Neural Regen Res. 2026 May 14.. View in PubMed
  • Single cell profiling reveals GSM-15606 attenuates air pollution-induced inflammation and preserves hippocampal neurogenesis. bioRxiv. 2026 Jan 30.. View in PubMed
  • Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features. Elife. 2025 Aug 06; 13.. View in PubMed
  • Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features. bioRxiv. 2025 Apr 24.. View in PubMed
  • Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida. J Gerontol A Biol Sci Med Sci. 2025 04 07; 80(5).. View in PubMed
  • Astroglia’s role in synchronized spontaneous neuronal activity: from physiology to pathology. Front Cell Neurosci. 2025; 19:1544460.. View in PubMed
  • Pharmacological inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. Sci Rep. 2024 12 28; 14(1):31151.. View in PubMed
  • Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression. Cell Stem Cell. 2025 Feb 06; 32(2):293-301.e3.. View in PubMed
  • Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. bioRxiv. 2024 Apr 11.. View in PubMed
  • Subthreshold repetitive transcranial magnetic stimulation suppresses ketamine-induced poly population spikes in rat sensorimotor cortex. Front Neurosci. 2022; 16:998704.. View in PubMed