Michael Bottros

Clinical Associate Professor of Anesthesiology (Clinician Educator)

Medical Director of Pain Service and Clinical Coordinator for Pain Service-Keck

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Michael Bottros, MD, is Associate Professor of Anesthesiology at the Keck School of Medicine of the University of Southern California and the Clinical Operations and Medical Director of Pain Services at Keck School of Medicine of USC and LAC+USC. He is board certified in the field of Anesthesiology and sub-specialty of Pain Medicine.

Dr. Bottros is a nationally recognized leader in the field of acute and chronic pain management. As an acclaimed leader, he founded the Acute Pain Service in 2013 at Washington University School of Medicine in St. Louis which rapidly became an essential component of perioperative care for thousands of patients annually. Dr. Bottros’ administrative leadership has extended well beyond the Acute Pain Service to broadly impact the delivery of pain management across the Washington University Medical Center, and he became Associate Chief of the Washington University Pain Management Division in 2017. For his outstanding work in education, Dr. Bottros received several awards including the Department of Anesthesiology Teacher of the Year Award and Department of Surgery “Friend of the Surgery Resident Award”. He has also published numerous peer-reviewed scientific papers in the fields of Pain Medicine and Anesthesiology through highly-ranked journal publications and textbook contributions. In addition, he has been invited to speak at over 100 local, national, and international conferences.

His clinical interests include, but are not limited to, treating occipital neuralgia, cervicogenic headache, neck pain, low back pain, failed back surgery syndrome, neuropathy, complex regional pain syndrome, and chronic post-surgery pain. His advanced skill set includes the use of ultrasound, radiofrequency ablation, spinal cord stimulation, and vertebral augmentation in treating pain.

He is dedicated to using the full scope of multimodal, interdisciplinary pain management to provide personalized, effective care.


  • Assessment of Preoperative Opioid Use Prevalence and Clinical Outcomes in Pulmonary Resection Ann Thorac Surg. 2021 06; 111(6):1849-1857. . View in PubMed
  • Pharmacotherapy to Manage Central Post-Stroke Pain CNS Drugs. 2021 02; 35(2):151-160. . View in PubMed
  • Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Crossover Trial Clin J Pain. 2021 11 01; 38(2):65-76. . View in PubMed
  • Successful transforaminal epidural blood patch in a patient with multilevel spinal fusion Reg Anesth Pain Med. 2020 09; 45(9):746-749. . View in PubMed
  • Cognitive flexibility and persistent post-surgical pain: the FLEXCAPP prospective observational study Br J Anaesth. 2020 05; 124(5):614-622. . View in PubMed
  • Physical therapy management, surgical treatment, and patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic outlet syndrome J Vasc Surg. 2019 09; 70(3):832-841. . View in PubMed
  • Continuous epidural infusion in gynecologic oncology patients undergoing exploratory laparotomy: The new standard for decreased postoperative pain and opioid use Gynecol Oncol. 2019 05; 153(2):356-361. . View in PubMed
  • Pain. 2018 Jul; 159(7):1317-1324. . View in PubMed
  • Effect of Perioperative Gabapentin Use on Postsurgical Pain in Patients Undergoing Head and Neck Mucosal Surgery: A Randomized Clinical Trial JAMA Otolaryngol Head Neck Surg. 2018 11 01; 144(11):959-966. . View in PubMed
  • Epidurals in Pancreatic Resection Outcomes (E-PRO) study: protocol for a randomised controlled trial BMJ Open. 2018 01 26; 8(1):e018787. . View in PubMed
  • Associations between clinical diagnostic criteria and pretreatment patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic outlet syndromeJ Vasc Surg. 2017 08; 66(2):533-544. e2. . View in PubMed
  • Exercise-Enhanced, Ultrasound-Guided Anterior Scalene Muscle/Pectoralis Minor Muscle Blocks Can Facilitate the Diagnosis of Neurogenic Thoracic Outlet Syndrome in the High-Performance Overhead Athlete Am J Sports Med. 2017 01; 45(1):189-194. . View in PubMed
  • Current perspectives on intrathecal drug delivery J Pain Res. 2014; 7:615-26. . View in PubMed
  • The effect of nitrous oxide anesthesia on early postoperative opioid consumption and pain Reg Anesth Pain Med. 2014 Jan-Feb; 39(1):31-6. . View in PubMed
  • Preventing Chronic Pain following Acute Pain: Risk Factors, Preventive Strategies, and their Efficacy Eur J Pain Suppl. 2011 Nov 11; 5(2):365-372. . View in PubMed
  • Prevention of intraoperative awareness in a high-risk surgical population N Engl J Med. 2011 Aug 18; 365(7):591-600. . View in PubMed
  • Estimation of the bispectral index by anesthesiologists: an inverse turing test Anesthesiology. 2011 May; 114(5):1093-101. . View in PubMed
  • Urine drug testing in chronic pain Pain Physician. 2011 Mar-Apr; 14(2):123-43. . View in PubMed
  • Bispectral index monitoring, duration of bispectral index below 45, patient risk factors, and intermediate-term mortality after noncardiac surgery in the B-Unaware Trial Anesthesiology. 2011 Mar; 114(3):545-56. . View in PubMed
  • Association of perioperative risk factors and cumulative duration of low bispectral index with intermediate-term mortality after cardiac surgery in the B-Unaware Trial Anesthesiology. 2010 May; 112(5):1116-27. . View in PubMed
  • Prevalence of undiagnosed obstructive sleep apnea among adult surgical patients in an academic medical center Sleep Med. 2009 Aug; 10(7):753-8. . View in PubMed
  • Anesthesia awareness and the bispectral index N Engl J Med. 2008 Mar 13; 358(11):1097-108. . View in PubMed
  • Optimizing motion scaling and magnification in robotic surgery Surgery. 2004 Aug; 136(2):291-4. . View in PubMed

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