Michael Donohue, PhD

Professor of Neurology

Image of Michael Donohue, PhD
Is this your profile? Click to edit

Overview

Michael Donohue, PhD is an Associate Professor of Neurology, Associate Director of Biostatistics at the Alzheimer’s Therapeutic Research Institute (ATRI), and Co-Lead of the Biostatistics Unit of the Alzheimer’s Clinical Trial Consortium (ACTC).

Since obtaining his PhD in Mathematics in 2005, Dr. Donohue has worked on Alzheimer’s clinical trials and observational studies, such as the Alzheimer’s Disease Neuroimaging Initiative (ADNI). His primary area of interest is applying novel statistical methods to data from ADNI to better understand the multivariate course of markers of Alzheimer’s progression, and design innovative clinical trials to prevent or slow the progression of disease. He has studied the risk of cognitive decline associated with elevated brain amyloid in cognitively normal individuals; and helped design the first intervention in asymptomatic Alzheimer’s, the Anti-Amyloid Treatment for Asymptomatic Alzheimer’s (the A4 Study; in collaboration with Eli Lilly), and its primary outcome measure, the Preclinical Alzheimer Cognitive Composite. He has been awarded grants to develop innovative statistical approaches for Alzheimer’s from the National Institute on Aging; the Alzheimer’s Association, Michael J. Fox Foundation, and W. Garfield Weston Foundation; and the Clinical and Translation Research Institute of University of California, San Diego

Publications

  • Paravertebral versus Pectoralis-II (Interpectoral and Pectoserratus) Nerve Blocks for Postoperative Analgesia after Non-Mastectomy Breast Surgery: A Randomized, Controlled, Observer-Masked Noninferiority Trial Anesthesiology. 2024 Aug 26. . View in PubMed
  • Rethinking the residual approach: Leveraging machine learning to operationalize cognitive resilience in Alzheimer’s disease medRxiv. 2024 Aug 20. . View in PubMed
  • Contributions of the ADNI Biostatistics Core Alzheimers Dement. 2024 Aug 14. . View in PubMed
  • The Alzheimer’s Disease Neuroimaging Initiative Clinical Core Alzheimers Dement. 2024 Aug 13. . View in PubMed
  • A Protocol for the Inclusion of Minoritized Persons in Alzheimer Disease Research From the ADNI3 Diversity Taskforce JAMA Netw Open. 2024 Aug 01; 7(8):e2427073. . View in PubMed
  • Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial Neurol Clin Pract. 2024 Apr; 14(2):e200265. . View in PubMed
  • Plasma Aß42/Aß40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer’s disease Alzheimers Dement. 2024 02; 20(2):1214-1224. . View in PubMed
  • Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer’s Disease J Prev Alzheimers Dis. 2024; 11(4):823-830. . View in PubMed
  • Characterizing Clinical Progression in Cognitively Unimpaired Older Individuals with Brain Amyloid: Results from the A4 Study J Prev Alzheimers Dis. 2024; 11(4):814-822. . View in PubMed
  • Pre-Randomization Predictors of Study Discontinuation in a Preclinical Alzheimer’s Disease Randomized Controlled Trial J Prev Alzheimers Dis. 2024; 11(4):874-880. . View in PubMed
  • Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies J Prev Alzheimers Dis. 2024; 11(4):802-813. . View in PubMed
  • Left Frontoparietal Control Network Connectivity Moderates the Effect of Amyloid on Cognitive Decline in Preclinical Alzheimer’s Disease: The A4 Study J Prev Alzheimers Dis. 2024; 11(4):881-888. . View in PubMed
  • Relationship between Plasma P-Tau217 and Amyloid PET in Racial and Ethnic Underrepresented Groups (RE-URG) Compared with Non RE-URG in LEARN and A4 J Prev Alzheimers Dis. 2024; 11(4):831-837. . View in PubMed
  • Change in Digital Cognitive Test Performance between Solanezumab and Placebo Groups in Preclinical Alzheimer’s Disease: Secondary Analyses from the A4 Study J Prev Alzheimers Dis. 2024; 11(4):846-856. . View in PubMed
  • The AlzMatch Pilot Study – Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer’s Disease Trials J Prev Alzheimers Dis. 2024; 11(5):1435-1444. . View in PubMed
  • Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau, and neurodegeneration Alzheimers Res Ther. 2024 07 03; 16(1):148. . View in PubMed
  • Longitudinal Trajectories of the Cognitive Function Index in the A4 Study J Prev Alzheimers Dis. 2024; 11(4):838-845. . View in PubMed
  • Maximizing the Utility of Alzheimer’s Disease Trial Data: Sharing of Baseline A4 and LEARN Data J Prev Alzheimers Dis. 2024; 11(4):889-894. . View in PubMed
  • Ascertainment and Statistical Issues for Randomized Trials of Cardiovascular Interventions for Cognitive Impairment and Dementia Hypertension. 2024 Jan; 81(1):45-53. . View in PubMed
  • Greater White Matter Hyperintensity Volume Is Associated with the Number of Microhemorrhages in Preclinical Alzheimer’s Disease J Prev Alzheimers Dis. 2024; 11(4):869-873. . View in PubMed
  • Two Phase 3 Trials of Gantenerumab in Early Alzheimer’s Disease N Engl J Med. 2023 Nov 16; 389(20):1862-1876. . View in PubMed
  • Trial of Solanezumab in Preclinical Alzheimer’s Disease N Engl J Med. 2023 Sep 21; 389(12):1096-1107. . View in PubMed
  • Natural cubic splines for the analysis of Alzheimer’s clinical trials Pharm Stat. 2023 May-Jun; 22(3):508-519. . View in PubMed
  • Safety and tolerability of lumbar puncture for the evaluation of Alzheimer’s disease Alzheimers Dement (Amst). 2023 Apr-Jun; 15(2):e12431. . View in PubMed
  • Heterogeneity in Preclinical Alzheimer’s Disease Trial Cohort Identified by Image-based Data-Driven Disease Progression Modelling medRxiv. 2023 Feb 10. . View in PubMed
  • The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer’s disease Alzheimers Dement. 2023 04; 19(4):1227-1233. . View in PubMed
  • Improving generalizability and study design of Alzheimer’s disease cohort studies in the United States by including under-represented populations Alzheimers Dement. 2023 04; 19(4):1549-1557. . View in PubMed
  • Why a clinical trial is as good as its outcome measure: A framework for the selection and use of cognitive outcome measures for clinical trials of Alzheimer’s disease Alzheimers Dement. 2023 02; 19(2):708-720. . View in PubMed
  • Tau positron emission tomography in preclinical Alzheimer’s disease Brain. 2023 02 13; 146(2):700-711. . View in PubMed
  • Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer’s Disease J Alzheimers Dis. 2023; 92(1):95-107. . View in PubMed
  • Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) Alzheimers Dement. 2022 12; 18(12):2603-2613. . View in PubMed
  • TurboID functions as an efficient biotin ligase for BioID applications in Xenopus embryos Dev Biol. 2022 12; 492:133-138. . View in PubMed
  • Amyloid-Related Imaging Abnormalities and Other MRI Findings in a Cognitively Unimpaired Population With and Without Cerebral Amyloid J Prev Alzheimers Dis. 2022; 9(4):617-624. . View in PubMed
  • Preoperative Ultrasound-guided Percutaneous Cryoneurolysis for the Treatment of Pain after Mastectomy: A Randomized, Participant- and Observer-masked, Sham-controlled Study Anesthesiology. 2022 11 01; 137(5):529-542. . View in PubMed
  • Basal Infusion versus Automated Boluses and a Delayed Start Timer for “Continuous” Sciatic Nerve Blocks after Ambulatory Foot and Ankle Surgery: A Randomized Clinical Trial Anesthesiology. 2022 06 01; 136(6):970-982. . View in PubMed
  • Sensitivity of the Preclinical Alzheimer’s Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheimer’s Disease -Atabecestat Phase 2b/3 EARLY Clinical Trial J Prev Alzheimers Dis. 2022; 9(2):255-261. . View in PubMed
  • Serratus anterior plane versus paravertebral nerve blocks for postoperative analgesia after non-mastectomy breast surgery: a randomized controlled non-inferiority trial Reg Anesth Pain Med. 2021 09; 46(9):773-778. . View in PubMed
  • The Computerized Cognitive Composite (C3) in an Alzheimer’s Disease Secondary Prevention Trial J Prev Alzheimers Dis. 2021; 8(1):59-67. . View in PubMed
  • Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) trial Alzheimers Dement (Amst). 2021; 13(1):e12199. . View in PubMed
  • Time between milestone events in the Alzheimer’s disease amyloid cascade Neuroimage. 2021 02 15; 227:117676. . View in PubMed
  • Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data J Prev Alzheimers Dis. 2021; 8(3):257-262. . View in PubMed
  • Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study Alzheimers Dement (N Y). 2021; 7(1):e12135. . View in PubMed
  • Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial JAMA Neurol. 2021 03 01; 78(3):293-301. . View in PubMed
  • Response to: ‘erector spinae plane and paravertebral blocks have similar opioid-sparing effects following breast surgery Reg Anesth Pain Med. 2020 Mar 26. . View in PubMed
  • Initiation of symptomatic medication in Alzheimer’s disease clinical trials: Hypothetical versus treatment policy approach Alzheimers Dement. 2020 05; 16(5):797-803. . View in PubMed
  • The A4 study: ß-amyloid and cognition in 4432 cognitively unimpaired adults Ann Clin Transl Neurol. 2020 05; 7(5):776-785. . View in PubMed
  • Erector spinae plane versus paravertebral nerve blocks for postoperative analgesia after breast surgery: a randomized clinical trial Reg Anesth Pain Med. 2020 04; 45(4):260-266. . View in PubMed
  • Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment JAMA Neurol. 2020 12 01; 77(12):1504-1513. . View in PubMed
  • Effect of apolipoprotein E e4 allele on the progression of cognitive decline in the early stage of Alzheimer’s disease Alzheimers Dement (N Y). 2020; 6(1):e12007. . View in PubMed
  • Predicting Amyloid Burden to Accelerate Recruitment of Secondary Prevention Clinical Trials J Prev Alzheimers Dis. 2020; 7(4):213-218. . View in PubMed
  • Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study Alzheimers Dement (Amst). 2020; 12(1):e12118. . View in PubMed
  • The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer’s Disease (TRC-PAD) Project: An Overview J Prev Alzheimers Dis. 2020; 7(4):208-212. . View in PubMed
  • TRC-PAD: Accelerating Recruitment of AD Clinical Trials through Innovative Information Technology J Prev Alzheimers Dis. 2020; 7(4):226-233. . View in PubMed
  • Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals JAMA Neurol. 2020 06 01; 77(6):735-745. . View in PubMed
  • Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial JAMA Neurol. 2020 09 01; 77(9):1099-1109. . View in PubMed
  • Neuroanatomical spread of amyloid ß and tau in Alzheimer’s disease: implications for primary prevention Brain Commun. 2020; 2(1):fcaa007. . View in PubMed
  • Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial JAMA Neurol. 2019 Oct 01; 76(10):1219-1229. . View in PubMed
  • Predicting the course of Alzheimer’s progression Brain Inform. 2019 Jun 28; 6(1):6. . View in PubMed
  • Continuous Popliteal-Sciatic Blocks for Postoperative Analgesia: Traditional Proximal Catheter Insertion Superficial to the Paraneural Sheath Versus a New Distal Insertion Site Deep to the Paraneural Sheath Anesth Analg. 2019 06; 128(6):e104-e108. . View in PubMed
  • A randomized clinical trial to evaluate home-based assessment of people over 75 years old Alzheimers Dement. 2019 05; 15(5):615-624. . View in PubMed
  • Predicting diagnosis and cognition with 18F-AV-1451 tau PET and structural MRI in Alzheimer’s disease Alzheimers Dement. 2019 04; 15(4):570-580. . View in PubMed
  • Bayesian latent time joint mixed effect models for multicohort longitudinal data Stat Methods Med Res. 2019 03; 28(3):835-845. . View in PubMed
  • The relative efficiency of time-to-progression and continuous measures of cognition in presymptomatic Alzheimer’s disease Alzheimers Dement (N Y). 2019; 5:308-318. . View in PubMed
  • Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers Neuroimage. 2019 02 01; 186:446-454. . View in PubMed
  • Plasma Neurofilament Light and Alzheimer’s Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI) J Alzheimers Dis. 2019; 70(1):131-138. . View in PubMed
  • Participant satisfaction with dementia prevention research: Results from Home-Based Assessment trial Alzheimers Dement. 2018 11; 14(11):1397-1405. . View in PubMed
  • Sex, amyloid, and APOE e4 and risk of cognitive decline in preclinical Alzheimer’s disease: Findings from three well-characterized cohorts Alzheimers Dement. 2018 09; 14(9):1193-1203. . View in PubMed
  • Response to Zywieck and Kirkby paper Neurobiol Aging. 2018 09; 69:298-299. . View in PubMed
  • Japanese and North American Alzheimer’s Disease Neuroimaging Initiative studies: Harmonization for international trials Alzheimers Dement. 2018 08; 14(8):1077-1087. . View in PubMed
  • Anesth Analg. 2018 07; 127(1):240-246. . View in PubMed
  • Disease progression models for dominantly-inherited Alzheimer’s disease Brain. 2018 05 01; 141(5):1244-1246. . View in PubMed
  • Estimating the Evolution of Disease in the Parkinson’s Progression Markers Initiative Neurodegener Dis. 2018; 18(4):173-190. . View in PubMed
  • Bayesian latent time joint mixed-effects model of progression in the Alzheimer’s Disease Neuroimaging Initiative Alzheimers Dement (Amst). 2018; 10:657-668. . View in PubMed
  • Defining the Optimal Target Population for Trials of Polyunsaturated Fatty Acid Supplementation Using the Erythrocyte Omega-3 Index: A Step Towards Personalized Prevention of Cognitive Decline? J Nutr Health Aging. 2018; 22(8):982-998.. View in PubMed
  • Early and late change on the preclinical Alzheimer’s cognitive composite in clinically normal older individuals with elevated amyloid ß Alzheimers Dement. 2017 Sep; 13(9):1004-1012. . View in PubMed
  • Infection Rates of Electrical Leads Used for Percutaneous Neurostimulation of the Peripheral Nervous System Pain Pract. 2017 07; 17(6):753-762. . View in PubMed
  • Anesth Analg. 2017 04; 124(4):1298-1303. . View in PubMed
  • EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer’s Prevention Trials J Prev Alzheimers Dis. 2017; 4(2):116-124. . View in PubMed
  • Elevated Brain Amyloid in Cognitively Normal Individuals-Reply JAMA. 2017 10 10; 318(14):1393-1394. . View in PubMed
  • Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons JAMA. 2017 06 13; 317(22):2305-2316. . View in PubMed
  • Cross-validation of optimized composites for preclinical Alzheimer’s disease Alzheimers Dement (N Y). 2017 Jan; 3(1):123-129. . View in PubMed
  • Anesth Analg. 2016 May; 122(5):1689-95. . View in PubMed
  • Cognitive and functional changes associated with Aß pathology and the progression to mild cognitive impairment Neurobiol Aging. 2016 12; 48:172-181. . View in PubMed
  • Using social and mobile tools for weight loss in overweight and obese young adults (Project SMART): a 2 year, parallel-group, randomised, controlled trial Lancet Diabetes Endocrinol. 2016 09; 4(9):747-755. . View in PubMed
  • Accelerating rates of cognitive decline and imaging markers associated with ß-amyloid pathology Neurology. 2016 05 17; 86(20):1887-96. . View in PubMed
  • Global Alzheimer’s Platform Trial Ready Cohorts for the Prevention of Alzheimer’s Dementia J Prev Alzheimers Dis. 2016; 3(4):185-187. . View in PubMed
  • The transitional association between ß-amyloid pathology and regional brain atrophy Alzheimers Dement. 2015 Oct; 11(10):1171-9. . View in PubMed
  • Longitudinal plasma amyloid beta in Alzheimer’s disease clinical trials Alzheimers Dement. 2015 Sep; 11(9):1069-79. . View in PubMed
  • The Alzheimer’s Disease Neuroimaging Initiative phase 2: Increasing the length, breadth, and depth of our understanding Alzheimers Dement. 2015 Jul; 11(7):823-31. . View in PubMed
  • Alzheimer’s Disease Neuroimaging Initiative 2 Clinical Core: Progress and plans Alzheimers Dement. 2015 Jul; 11(7):734-9. . View in PubMed
  • Impact of the Alzheimer’s Disease Neuroimaging Initiative, 2004 to 2014 Alzheimers Dement. 2015 Jul; 11(7):865-84. . View in PubMed
  • Clinical trial management of participant recruitment, enrollment, engagement, and retention in the SMART study using a Marketing and Information Technology (MARKIT) model Contemp Clin Trials. 2015 May; 42:185-95. . View in PubMed
  • Predicting Reduction of Cerebrospinal Fluid ß-Amyloid 42 in Cognitively Healthy Controls JAMA Neurol. 2015 May; 72(5):554-60. . View in PubMed
  • Biomarkers and cognitive endpoints to optimize trials in Alzheimer’s disease Ann Clin Transl Neurol. 2015 May; 2(5):534-47. . View in PubMed
  • Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer’s Disease Cooperative Study Cognitive Function Instrument JAMA Neurol. 2015 Apr; 72(4):446-54. . View in PubMed
  • Independent information from cerebrospinal fluid amyloid-ß and florbetapir imaging in Alzheimer’s disease Brain. 2015 Mar; 138(Pt 3):772-83. . View in PubMed
  • The down syndrome biomarker initiative (DSBI) pilot: proof of concept for deep phenotyping of Alzheimer’s disease biomarkers in down syndrome Front Behav Neurosci. 2015; 9:239. . View in PubMed
  • A randomized, triple-masked, active-controlled investigation of the relative effects of dose, concentration, and infusion rate for continuous popliteal-sciatic nerve blocks in volunteers Br J Anaesth. 2015 Jan; 114(1):121-9. . View in PubMed
  • J Alzheimers Dis. 2015; 48(1):205-18. . View in PubMed
  • Impact of CRFR1 Ablation on Amyloid-ß Production and Accumulation in a Mouse Model of Alzheimer’s Disease J Alzheimers Dis. 2015; 45(4):1175-84. . View in PubMed
  • Estimating long-term multivariate progression from short-term data Alzheimers Dement. 2014 Oct; 10(5 Suppl):S400-10. . View in PubMed
  • The preclinical Alzheimer cognitive composite: measuring amyloid-related decline JAMA Neurol. 2014 Aug; 71(8):961-70. . View in PubMed
  • Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer’s disease Ann Clin Transl Neurol. 2014 Aug; 1(8):534-43. . View in PubMed
  • Emerging ß-amyloid pathology and accelerated cortical atrophy JAMA Neurol. 2014 Jun; 71(6):725-34. . View in PubMed
  • Association of brain amyloid-ß with cerebral perfusion and structure in Alzheimer’s disease and mild cognitive impairment Brain. 2014 May; 137(Pt 5):1550-61. . View in PubMed
  • The A4 study: stopping AD before symptoms begin? Sci Transl Med. 2014 Mar 19; 6(228):228fs13.. View in PubMed
  • Design and implementation of a randomized controlled social and mobile weight loss trial for young adults (project SMART) Contemp Clin Trials. 2014 Jan; 37(1):10-8. . View in PubMed
  • Liposomal bupivacaine as a single-injection peripheral nerve block: a dose-response study Anesth Analg. 2013 Nov; 117(5):1248-56. . View in PubMed
  • Developing dementia prevention trials: baseline report of the Home-Based Assessment study Alzheimer Dis Assoc Disord. 2013 Oct-Dec; 27(4):356-62. . View in PubMed
  • Ultrasound-guided root/trunk (interscalene) block for hand and forearm anesthesia Reg Anesth Pain Med. 2013 May-Jun; 38(3):226-32. . View in PubMed
  • Tracking pathophysiological processes in Alzheimer’s disease: an updated hypothetical model of dynamic biomarkers Lancet Neurol. 2013 Feb; 12(2):207-16. . View in PubMed
  • Continuous femoral nerve blocks: the impact of catheter tip location relative to the femoral nerve (anterior versus posterior) on quadriceps weakness and cutaneous sensory block Anesth Analg. 2012 Sep; 115(3):721-7. . View in PubMed
  • Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD) J Hepatol. 2012 Aug; 57(2):384-91. . View in PubMed
  • Impact of surgically induced weight loss on pelvic floor disorders Int Urogynecol J. 2012 Aug; 23(8):1111-6. . View in PubMed
  • Interact J Med Res. 2012 Apr 04; 1(1):e1. . View in PubMed
  • Mixed model of repeated measures versus slope models in Alzheimer’s disease clinical trials J Nutr Health Aging. 2012 Apr; 16(4):360-4. . View in PubMed
  • Alzheimer’s disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology J Nutr Health Aging. 2012 Apr; 16(4):339-45. . View in PubMed
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. . View in PubMed
  • Continuous femoral nerve blocks: decreasing local anesthetic concentration to minimize quadriceps femoris weakness Anesthesiology. 2012 Mar; 116(3):665-72. . View in PubMed
  • Proximal sural traction neurectomy during transtibial amputations J Orthop Trauma. 2012 Feb; 26(2):123-6. . View in PubMed
  • Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study PLoS One. 2012; 7(3):e31516. . View in PubMed
  • Continuous femoral versus posterior lumbar plexus nerve blocks for analgesia after hip arthroplasty: a randomized, controlled study Anesth Analg. 2011 Oct; 113(4):897-903. . View in PubMed
  • Continuous femoral nerve blocks: varying local anesthetic delivery method (bolus versus basal) to minimize quadriceps motor block while maintaining sensory block Anesthesiology. 2011 Oct; 115(4):774-81. . View in PubMed
  • The relative efficiency of time-to-threshold and rate of change in longitudinal data Contemp Clin Trials. 2011 Sep; 32(5):685-93. . View in PubMed
  • Conditional Akaike information under generalized linear and proportional hazards mixed models Biometrika. 2011 Sep; 98(3):685-700. . View in PubMed
  • Predictors of response to an attention modification program in generalized social phobia J Consult Clin Psychol. 2011 Aug; 79(4):533-41. . View in PubMed
  • Pirfenidone for diabetic nephropathy J Am Soc Nephrol. 2011 Jun; 22(6):1144-51. . View in PubMed
  • Clinical evidence for predominance of delta-5 steroid production in women with polycystic ovary syndrome J Clin Endocrinol Metab. 2011 Apr; 96(4):1106-13. . View in PubMed
  • Requiring an amyloid-ß1-42 biomarker for prodromal Alzheimer’s disease or mild cognitive impairment does not lead to more efficient clinical trials Alzheimers Dement. 2011 Mar; 7(2):245-6; author reply 247-9. . View in PubMed
  • Report of the task force on designing clinical trials in early (predementia) AD Neurology. 2011 Jan 18; 76(3):280-6. . View in PubMed
  • The association between lower extremity continuous peripheral nerve blocks and patient falls after knee and hip arthroplasty Anesth Analg. 2010 Dec; 111(6):1552-4. . View in PubMed
  • Six-month atrophy in MTL structures is associated with subsequent memory decline in elderly controls Neuroimage. 2010 Dec; 53(4):1310-7. . View in PubMed
  • Adenovirus 36 and obesity in children and adolescents Pediatrics. 2010 Oct; 126(4):721-6. . View in PubMed
  • Enrichment through biomarkers in clinical trials of Alzheimer’s drugs in patients with mild cognitive impairmentNeurobiol Aging. 2010 Aug; 31(8):1443-511451. e1. . View in PubMed
  • Pilot study to show the feasibility of a multicenter trial of home-based assessment of people over 75 years old Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):256-63. . View in PubMed
  • The Alzheimer’s Disease Neuroimaging Initiative: Annual change in biomarkers and clinical outcomes Alzheimers Dement. 2010 May; 6(3):257-64. . View in PubMed
  • Clinical Core of the Alzheimer’s Disease Neuroimaging Initiative: progress and plans Alzheimers Dement. 2010 May; 6(3):239-46. . View in PubMed
  • Continuous peripheral nerve blocks: is local anesthetic dose the only factor, or do concentration and volume influence infusion effects as well? Anesthesiology. 2010 Feb; 112(2):347-54.. View in PubMed
  • Alzheimer’s Disease Neuroimaging Initiative (ADNI): clinical characterization Neurology. 2010 Jan 19; 74(3):201-9. . View in PubMed
  • Comparison of inhibin B and estradiol responses to intravenous FSH in women with polycystic ovary syndrome and normal women Hum Reprod. 2010 Jan; 25(1):198-203. . View in PubMed
  • rTMS for suppressing neuropathic pain: a meta-analysis J Pain. 2009 Dec; 10(12):1205-16. . View in PubMed
  • Modular psychotherapy for anxiety in older primary care patients Am J Geriatr Psychiatry. 2009 Jun; 17(6):483-92. . View in PubMed
  • Pediatricians’ weight assessment and obesity management practices BMC Pediatr. 2009 Mar 05; 9:19. . View in PubMed
  • Applications of neuroimaging to disease-modification trials in Alzheimer’s disease Behav Neurol. 2009; 21(1):129-36. . View in PubMed
  • Peripheral blood progenitor cell mobilization with intermediate-dose cyclophosphamide, sequential granulocyte-macrophage-colony-stimulating factor and granulocyte-colony-stimulating factor, and scheduled commencement of leukapheresis in 225 patients undergoing autologous transplantation Transfusion. 2007 Nov; 47(11):2153-60. . View in PubMed
  • EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement Gastrointest Endosc. 2007 Aug; 66(2):277-82. . View in PubMed
  • Parental ability to discriminate the weight status of children: results of a survey Pediatrics. 2007 Jul; 120(1):e112-9. . View in PubMed
  • Anopheles gambiae pilot gene discovery project: identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6619-24. . View in PubMed
  • High-dose cisplatin-related peripheral neuropathy Cancer Nurs. 1988 Feb; 11(1):23-32. . View in PubMed
  • Altered disc compression in children with idiopathic low back pain: an upright magnetic resonance imaging backpack study Spine (Phila Pa 1976). 2014 Feb 01; 39(3):243-8. . View in PubMed