Nathanael Heckmann, MD

Associate Professor of Orthopaedic Surgery (Clinical Scholar)

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Overview

Dr. Nathanael Heckmann is an Associate Professor of Orthopaedic Surgery and a Clinical Scholar at the Keck School of Medicine of USC, where he also serves as Director of Arthroplasty Research in the Department of Orthopaedic Surgery.

His surgical practice focuses on treating degenerative diseases of the hip and knee, such as osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis. Dr. Heckmann performs a range of advanced procedures, including minimally invasive total hip and knee replacement, partial knee replacement, surgery to fix infected and failed hip and knee replacements, and robotic-assisted and computer-navigated arthroplasty.

Dr. Heckmann’s research focuses on clinical outcomes following hip and knee arthroplasty. His specific areas of inquiry include the diagnosis, treatment, and management of infected hip and knee replacements; perioperative patient optimization, including preoperative risk stratification and postoperative risk mitigation strategies; and exploring the relationship between the human gut microbiome and surgical outcomes.

He holds leadership positions in the American Academy of Orthopaedic Surgeons, the American Association of Hip and Knee Surgeons, and the Western Orthopaedic Association. He is also a member of The Hip Society and The Knee Society. Dr. Heckmann has authored 18 textbook chapters and over 240 peer-reviewed publications. His research has been presented over 350 times at national and international conferences.

Awards

  • Super Doctors: Rising Star, 2021
     – 2025
  • Pasadena Magazine: Top Doctor, 2021
     – 2025
  • Southern California Top Doctor & Rising Star, 2021
     – 2025
  • Los Angeles Magazine: Top Doctor, 2021
     – 2025
  • Western Orthopaedic Association: Young Investigator Award, 2023
     – 2025

Media

Publications

  • Operative care rates of lateral compression type 1 pelvic fractures increased from 2003 to 2018. Eur J Orthop Surg Traumatol. 2026 Aug 01; 36(1).. View in PubMed
  • Precision and Accuracy of Polyethylene Thickness in Total Knee Arthroplasty: A Comparison of Conventional Measured Resection and Robotic-Assisted Techniques. Arthroplast Today. 2026 Aug; 40:102097.. View in PubMed
  • Perioperative Dexamethasone Is Associated With a Reduced Risk of Periprosthetic Joint Infection Following Aseptic Revision Total Hip and Knee Arthroplasty. Arthroplast Today. 2026 Aug; 40:102100.. View in PubMed
  • Predictive Factors for Manipulations Under Anesthesia After Total Knee Arthroplasty: An Analysis of 15,139 Cases. J Am Acad Orthop Surg. 2026 Jul 23.. View in PubMed
  • A Comparative Analysis of Lower Extremity Deformity Correction: Two-dimensional versus Three-dimensional Computed Tomography. J Knee Surg. 2026 Jul 16.. View in PubMed
  • Dexamethasone Is Associated With a Dose-Dependent Reduction in Venous Thromboembolic Complications Following Total Knee and Hip Arthroplasty. J Arthroplasty. 2026 Jul 16.. View in PubMed
  • Inflammatory Bowel Disease and Periprosthetic Joint Infection Following Total Joint Arthroplasty: Crohn’s Disease and Ulcerative Colitis Associated With Varying Risk. Arthroplast Today. 2026 Aug; 40:102077.. View in PubMed
  • Risk of Total Hip Arthroplasty After Sacroiliac Joint Fusion Surgery: A Nationwide Study. Global Spine J. 2026 Jul 02; 21925682261463491.. View in PubMed
  • Complication and Reoperation Rates of Post-Distal Femoral Osteotomy Total Knee Arthroplasty versus Primary Total Knee Arthroplasty: Matched Cohorts from a Nationwide Database. J Arthroplasty. 2026 Jun 29.. View in PubMed
  • Reassessing Total Joint Arthroplasty Case Volumes in the United States: Accounting for Ultralow-Volume Surgeons. J Arthroplasty. 2026 Jun 27.. View in PubMed