Parviz Minoo, PhD

Professor of Pediatrics

Director of the USC Hastings Center for Pulmonary Research

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Research Funding

  • Transitional Alveolar Epithelial Cells in Normal Lung Development
    NIH · R01HL176777 · Sep 10, 2025 – Jun 30, 2029 · Role: Principal Investigator
  • WNT5a Regulates Lung Maturation
    NIH · R01HL144932 · Mar 6, 2019 – Feb 29, 2024 · Role: Co-Principal Investigator
  • Postnatal Alveolar Formation
    NIH · R01HL143059 · Sep 1, 2018 – Jul 31, 2022 · Role: Principal Investigator
  • THE BIOLOGY OF PULMONARY ALVEOLAR FORMATION
    NIH · R01HL122764 · Jan 1, 2015 – Dec 31, 2018 · Role: Principal Investigator
  • MECHANISMS OF BPD PATHOGENESIS
    NIH · R01HL107307 · Jan 1, 2012 – Nov 30, 2016 · Role: Principal Investigator
  • Mechanisms of Lung Development and Injury
    NIH · R01HL095349 · Dec 1, 2008 – Jun 30, 2019 · Role: Principal Investigator
  • Interactive Mediators of Injury &Development
    NIH · R01HL073471 · Dec 15, 2003 – Nov 30, 2009 · Role: Principal Investigator
  • Molecular Basis of Lung Morphogenesis Injury &Repair
    NIH · P01HL060231 · Apr 1, 1998 – Mar 31, 2011 · Role: Co-Principal Investigator
  • Pulmonary Development: Molecular & Cellular Analysis
    NIH · R01HL056590 · Aug 1, 1996 – Mar 31, 2014 · Role: Principal Investigator
  • TTF-L AND MECHANISMS OF BPD
    NIH · U10HL056221 · Sep 30, 1995 – Aug 31, 1999 · Role: Principal Investigator
  • PULMONARY TYPE II CELL DEVELOPMENT–CLONING OF CDNA'S
    NIH · R01HL048298 · Jan 1, 1993 – Jan 31, 1998 · Role: Principal Investigator

Publications

  • AKT Signaling Differentially Regulates the Expression of Two Evolutionarily Conserved Wnt5a Isoforms in Lung Mesenchymal Cells. Cells. 2026 May 04; 15(9).. View in PubMed
  • Non-invasive respiratory support attenuates lung damage in a murine model of bronchopulmonary dysplasia. Front Pediatr. 2026; 14:1755113.. View in PubMed
  • Should nasal respiratory support in preterm infants be tailored for physiologic maturity? Pediatr Res. 2024 05; 95(6):1402-1403. Biniwale M, Ramanathan R, Minoo P . . View in PubMed
  • GRAMD2 + alveolar type I cell plasticity facilitates cell state transitions in organoid culture. bioRxiv. 2023 Oct 18.. View in PubMed
  • Decoding the IGF1 signaling gene regulatory network behind alveologenesis from a mouse model of bronchopulmonary dysplasia. Elife. 2022 10 10; 11.. View in PubMed
  • Wnt5a Promotes AT1 and Represses AT2 Lineage-Specific Gene Expression in a Cell-Context-Dependent Manner. Stem Cells. 2022 07 27; 40(7):691-703.. View in PubMed
  • FGF10 Triggers De Novo Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells. Stem Cells. 2022 06 22; 40(6):605-617.. View in PubMed
  • Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis. Cell Rep. 2022 04 05; 39(1):110608.. View in PubMed
  • FOXO1 Couples KGF and PI-3K/AKT Signaling to NKX2.1-Regulated Differentiation of Alveolar Epithelial Cells. Cells. 2022 03 26; 11(7).. View in PubMed
  • Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy. Eur Respir J. 2021 10; 58(5).. View in PubMed