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Paul Fraser Kantor

Professor of Pediatrics (Clinical Scholar)

Division Chief of Cardiology

Co-Executive Director of the Heart Institute at CHLA

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Email pfkantor@usc.edu
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Publications

  • Association between NT-proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA-HF and PARADIGM-HF. ESC Heart Fail. 2025 Aug; 12(4):3042-3052.. View in PubMed
  • Genetic Testing Resources and Practice Patterns Among Pediatric Cardiomyopathy Programs. Pediatr Cardiol. 2025 Apr; 46(4):798-803.. View in PubMed
  • Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-Blind Trial. Circulation. 2024 Nov 26; 150(22):1756-1766.. View in PubMed
  • Association Between Serial B-Type Natriuretic Peptide Levels, Vasoactive Drug Weaning, and Adverse Cardiovascular Outcomes in Pediatric Heart Failure. J Am Heart Assoc. 2024 Aug 20; 13(16):e031132.. View in PubMed
  • Progressive Left Ventricular Remodeling for Predicting Mortality in Children With Dilated Cardiomyopathy: The Pediatric Cardiomyopathy Registry. J Am Heart Assoc. 2024 Jan 16; 13(2):e022557.. View in PubMed
  • Shedding Light on the Darkness of MYH7 Cardiomyopathies. JACC Heart Fail. 2024 01; 12(1):148-149.. View in PubMed
  • Cardiac imaging and biomarkers for assessing myocardial fibrosis in children with hypertrophic cardiomyopathy. Am Heart J. 2023 10; 264:153-162.. View in PubMed
  • Risk of Sudden Death in Patients With RASopathy Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2023 03 21; 81(11):1035-1045.. View in PubMed
  • Baseline Characteristics of Pediatric Patients With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction in the PANORAMA-HF Trial. Circ Heart Fail. 2023 03; 16(3):e009816.. View in PubMed
  • The Prevalence and Association of Exercise Test Abnormalities With Sudden Cardiac Death and Transplant-Free Survival in Childhood Hypertrophic Cardiomyopathy. Circulation. 2023 02 28; 147(9):718-727.. View in PubMed
  • QTc and QRS Abnormalities are Associated with Outcome in Pediatric Heart Failure. Pediatr Cardiol. 2022 Dec; 43(8):1903-1912.. View in PubMed
  • Drug Treatment of Heart Failure in Children: Gaps and Opportunities. Paediatr Drugs. 2022 Mar; 24(2):121-136.. View in PubMed
  • The genetic architecture of pediatric cardiomyopathy. Am J Hum Genet. 2022 02 03; 109(2):282-298.. View in PubMed
  • Non-invasive biomarkers of Fontan-associated liver disease. JHEP Rep. 2021 Dec; 3(6):100362.. View in PubMed
  • Genetic Causes of Cardiomyopathy in Children: First Results From the Pediatric Cardiomyopathy Genes Study. J Am Heart Assoc. 2021 05 04; 10(9):e017731.. View in PubMed
  • Response by Mital et al to Letter Regarding Article, “A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy”. Circulation. 2021 03 16; 143(11):e788-e789.. View in PubMed
  • Recent and Upcoming Drug Therapies for Pediatric Heart Failure. Front Pediatr. 2021; 9:681224.. View in PubMed
  • Hypertrophic Cardiomyopathy in Adolescence: Application of Guidelines. JACC Case Rep. 2021 Jan; 3(1):10-15.. View in PubMed
  • Elevated Heart Rate and Survival in Children With Dilated Cardiomyopathy: A Multicenter Study From the Pediatric Cardiomyopathy Registry. J Am Heart Assoc. 2020 08 04; 9(15):e015916.. View in PubMed
  • A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. Circulation. 2020 07 21; 142(3):217-229.. View in PubMed
  • Update on pediatric heart failure. Curr Opin Pediatr. 2019 10; 31(5):598-603.. View in PubMed
  • Correction: Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2019 Oct; 21(10):2406-2409.. View in PubMed
  • The clinical impact of donor-specific antibodies on antibody-mediated rejection and long-term prognosis after heart transplantation. Curr Opin Organ Transplant. 2019 06; 24(3):245-251.. View in PubMed
  • Cardiac Biomarkers in Pediatric Cardiomyopathy: Study Design and Recruitment Results from the Pediatric Cardiomyopathy Registry. Prog Pediatr Cardiol. 2019 Jun; 53:1-10.. View in PubMed
  • Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts. J Am Heart Assoc. 2018 10 02; 7(19):e010427.. View in PubMed
  • Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2018 09; 20(9):899-909.. View in PubMed
  • Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline. J Card Fail. 2018 May; 24(5):281-302.. View in PubMed
  • No Obesity Paradox in Pediatric Patients With Dilated Cardiomyopathy. JACC Heart Fail. 2018 03; 6(3):222-230.. View in PubMed
  • Survival Without Cardiac Transplantation Among Children With Dilated Cardiomyopathy. J Am Coll Cardiol. 2017 Nov 28; 70(21):2663-2673.. View in PubMed
  • Design for the sacubitril/valsartan (LCZ696) compared with enalapril study of pediatric patients with heart failure due to systemic left ventricle systolic dysfunction (PANORAMA-HF study). Am Heart J. 2017 Nov; 193:23-34.. View in PubMed
  • The Utility of Cardiopulmonary Exercise Testing for the Prediction of Outcomes in Ambulatory Children With Dilated Cardiomyopathy. Transplantation. 2017 10; 101(10):2455-2460.. View in PubMed
  • Ivabradine in Children With Dilated Cardiomyopathy and Symptomatic Chronic Heart Failure. J Am Coll Cardiol. 2017 Sep 05; 70(10):1262-1272.. View in PubMed
  • Abnormal Myocardial Contractility After Pediatric Heart Transplantation by Cardiac MRI. Pediatr Cardiol. 2017 Aug; 38(6):1198-1205.. View in PubMed
  • Histological validation of cardiovascular magnetic resonance T1 mapping markers of myocardial fibrosis in paediatric heart transplant recipients. J Cardiovasc Magn Reson. 2017 Feb 01; 19(1):10.. View in PubMed
  • Prevalence and Severity of Anemia in Children Hospitalized with Acute Heart Failure. Congenit Heart Dis. 2016 Dec; 11(6):622-629.. View in PubMed
  • Incidence, Severity, and Association With Adverse Outcome of Hyponatremia in Children Hospitalized With Heart Failure. Am J Cardiol. 2016 Oct 01; 118(7):1006-10.. View in PubMed
  • Angiotensin-Converting Enzyme Inhibitor Initiation and Dose Uptitration in Children With Cardiovascular Disease: A Retrospective Review of Standard Clinical Practice and a Prospective Randomized Clinical Trial. J Am Heart Assoc. 2016 05 20; 5(5).. View in PubMed
  • Preventing pediatric cardiomyopathy: a 2015 outlook. Expert Rev Cardiovasc Ther. 2016; 14(3):321-39.. View in PubMed
  • Prevalence, predictors, and outcomes of cardiorenal syndrome in children with dilated cardiomyopathy: a report from the Pediatric Cardiomyopathy Registry. Pediatr Nephrol. 2015 Dec; 30(12):2177-88.. View in PubMed
  • Diffuse Myocardial Fibrosis in Children After Heart Transplantations: A Magnetic Resonance T1 Mapping Study. Transplantation. 2015 Dec; 99(12):2656-62.. View in PubMed
  • Cardiomyopathy Phenotypes and Outcomes for Children With Left Ventricular Myocardial Noncompaction: Results From the Pediatric Cardiomyopathy Registry. J Card Fail. 2015 Nov; 21(11):877-84.. View in PubMed
  • Activating PPARα prevents post-ischemic contractile dysfunction in hypertrophied neonatal hearts. Circ Res. 2015 Jun 19; 117(1):41-51.. View in PubMed
  • Exercise echocardiography demonstrates biventricular systolic dysfunction and reveals decreased left ventricular contractile reserve in children after tetralogy of Fallot repair. J Am Soc Echocardiogr. 2015 Mar; 28(3):294-301.. View in PubMed
  • Prognostic implications of the systolic to diastolic duration ratio in children with idiopathic or familial dilated cardiomyopathy. Circ Cardiovasc Imaging. 2014 Sep; 7(5):773-80.. View in PubMed
  • Sleep-disordered breathing in children with cardiomyopathy. Ann Am Thorac Soc. 2014 Jun; 11(5):770-6.. View in PubMed
  • Factors associated with serum B-type natriuretic peptide in infants with single ventricles. Pediatr Cardiol. 2014 Jun; 35(5):879-87.. View in PubMed
  • Recovery of echocardiographic function in children with idiopathic dilated cardiomyopathy: results from the pediatric cardiomyopathy registry. J Am Coll Cardiol. 2014 Apr 15; 63(14):1405-13.. View in PubMed
  • Risk factors for mortality or delisting of patients from the pediatric heart transplant waiting list. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):462-8.. View in PubMed
  • Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines. Can J Cardiol. 2013 Dec; 29(12):1535-52.. View in PubMed
  • Heart failure in congenital heart disease. Can J Cardiol. 2013 Jul; 29(7):753-4.. View in PubMed
  • Relation of right ventricular mechanics to exercise tolerance in children after tetralogy of Fallot repair. Am Heart J. 2013 Apr; 165(4):551-7.. View in PubMed
  • Outcomes of cardiac transplantation in single-ventricle patients with plastic bronchitis: a multicenter study. J Am Coll Cardiol. 2013 Mar 05; 61(9):985-6.. View in PubMed
  • Impaired right and left ventricular diastolic myocardial mechanics and filling in asymptomatic children and adolescents after repair of tetralogy of Fallot. Eur Heart J Cardiovasc Imaging. 2012 Nov; 13(11):905-13.. View in PubMed
  • Sudden death in an infant with angina, restrictive cardiomyopathy, and coronary artery bridging: an unusual phenotype for a β-myosin heavy chain (MYH7) sarcomeric protein mutation. Circ Heart Fail. 2012 Nov; 5(6):e92-3.. View in PubMed
  • Outcomes of restrictive cardiomyopathy in childhood and the influence of phenotype: a report from the Pediatric Cardiomyopathy Registry. Circulation. 2012 Sep 04; 126(10):1237-44.. View in PubMed
  • Early predictors of survival to and after heart transplantation in children with dilated cardiomyopathy. Circulation. 2012 Aug 28; 126(9):1079-86.. View in PubMed
  • Influence of RV restrictive physiology on LV diastolic function in children after tetralogy of Fallot repair. J Am Soc Echocardiogr. 2012 Aug; 25(8):866-73.. View in PubMed
  • Impaired left ventricular myocardial mechanics and their relation to pulmonary regurgitation, right ventricular enlargement and exercise capacity in asymptomatic children after repair of tetralogy of Fallot. J Am Soc Echocardiogr. 2012 May; 25(5):494-503.. View in PubMed
  • Incidence of and risk factors for sudden cardiac death in children with dilated cardiomyopathy: a report from the Pediatric Cardiomyopathy Registry. J Am Coll Cardiol. 2012 Feb 07; 59(6):607-15.. View in PubMed
  • Pharmacologic therapy of heart failure in children: part of a special series on paediatric pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni. Pharmacol Res. 2011 Nov; 64(5):427-30.. View in PubMed
  • Undiagnosed heart disease leading to sudden unexpected death in childhood: a retrospective study. Pediatrics. 2011 Sep; 128(3):e513-20.. View in PubMed
  • Current applications and Future Needs for Biomarkers in Pediatric Cardiomyopathy and Heart Failure: Summary From The Second International Conference On Pediatric Cardiomyopathy. Prog Pediatr Cardiol. 2011 Aug 01; 32(1):11-14.. View in PubMed
  • Usefulness of mitral regurgitation as a marker of increased risk for death or cardiac transplantation in idiopathic dilated cardiomyopathy in children. Am J Cardiol. 2011 May 15; 107(10):1517-21.. View in PubMed
  • Isovolumic acceleration at rest and during exercise in children normal values for the left ventricle and first noninvasive demonstration of exercise-induced force-frequency relationships. J Am Coll Cardiol. 2011 Mar 01; 57(9):1100-7.. View in PubMed
  • Effectiveness of serial increases in amino-terminal pro-B-type natriuretic peptide levels to indicate the need for mechanical circulatory support in children with acute decompensated heart failure. Am J Cardiol. 2011 Feb 15; 107(4):573-8.. View in PubMed
  • Exercise induces biventricular mechanical dyssynchrony in children with repaired tetralogy of Fallot. Heart. 2010 Dec; 96(24):2010-5.. View in PubMed
  • Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry. Circ Heart Fail. 2010 Nov; 3(6):689-97.. View in PubMed
  • Dilated cardiomyopathy in epidermolysis bullosa: a retrospective, multicenter study. Pediatr Dermatol. 2010 May-Jun; 27(3):238-43.. View in PubMed
  • The impact of changing medical therapy on transplantation-free survival in pediatric dilated cardiomyopathy. J Am Coll Cardiol. 2010 Mar 30; 55(13):1377-84.. View in PubMed
  • Exercise capacity improves with time in pediatric heart transplant recipients. J Heart Lung Transplant. 2009 Jun; 28(6):585-90.. View in PubMed
  • Left ventricular diastolic mechanical dyssynchrony and associated clinical outcomes in children with dilated cardiomyopathy. Circ Cardiovasc Imaging. 2008 Jul; 1(1):50-7.. View in PubMed
  • Thoracoscopic ligation versus coil occlusion for patent ductus arteriosus: a matched cohort study of outcomes and cost. Surg Endosc. 2008 Jul; 22(7):1643-8.. View in PubMed
  • Surgical repair of the mitral valve in children with dilated cardiomyopathy and mitral regurgitation. Ann Thorac Surg. 2008 Jun; 85(6):2085-8.. View in PubMed
  • Clinical considerations for Heart Rhythm allied professionals: understanding heart failure in congenital heart disease patients. Heart Rhythm. 2007 Feb; 4(2):248-50.. View in PubMed

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