Keck School Faculty

Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes Nature. 2022 May; 605(7909):E3. . View in PubMed

FOXC1 Binds Enhancers and Promotes Cisplatin Resistance in Bladder Cancer Cancers (Basel). 2022 Mar 28; 14(7). . View in PubMed

Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability Genome Biol. 2022 07 26; 23(1):163. . View in PubMed

TENET 20: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma. PLoS Genet. 2020 09; 16(9):e1009023. . View in PubMed

Expanded encyclopaedias of DNA elements in the human and mouse genomes Nature. 2020 07; 583(7818):699-710. . View in PubMed

Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters Nucleic Acids Res. 2020 06 19; 48(11):5986-6000. . View in PubMed

Genome-wide analysis of HOXC4 and HOXC6 regulated genes and binding sites in prostate cancer cells PLoS One. 2020; 15(2):e0228590. . View in PubMed

The Enigmatic HOX Genes: Can We Crack Their Code? Cancers (Basel). 2019 Mar 07; 11(3).. View in PubMed

The prostate cancer risk variant rs55958994 regulates multiple gene expression through extreme long-range chromatin interaction to control tumor progression Sci Adv. 2019 07; 5(7):eaaw6710. . View in PubMed

Three-dimensional analysis reveals altered chromatin interaction by enhancer inhibitors harbors TCF7L2-regulated cancer gene signature J Cell Biochem. 2019 03; 120(3):3056-3070. . View in PubMed

A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome Nat Commun. 2019 09 12; 10(1):4154. . View in PubMed

Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner Epigenetics Chromatin. 2019 05 03; 12(1):26. . View in PubMed

ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream of transcription start sites at the majority of CpG island promoters Genome Res. 2018 Feb 02. . View in PubMed

Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation Sci Adv. 2018 12; 4(12):eaav8550. . View in PubMed

CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops Genome Biol. 2018 10 08; 19(1):160. . View in PubMed

Defining Regulatory Elements in the Human Genome Using Nucleosome Occupancy and Methylome Sequencing (NOMe-Seq) Methods Mol Biol. 2018; 1766:209-229. . View in PubMed

A Prostate Cancer Risk Element Functions as a Repressive Loop that Regulates HOXA13 Cell Rep. 2017 Nov 07; 21(6):1411-1417. . View in PubMed

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression Nucleic Acids Res. 2017 Sep 29; 45(17):9901-9916. . View in PubMed

4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus Sci Rep. 2016 Mar 03; 6:22462. . View in PubMed

Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells Nucleic Acids Res. 2016 05 19; 44(9):4123-33. . View in PubMed

Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits Epigenetics Chromatin. 2016; 9:50. . View in PubMed

The PsychENCODE project Nat Neurosci. 2015 Dec; 18(12):1707-12. . View in PubMed

Inferring regulatory element landscapes and transcription factor networks from cancer methylomes Genome Biol. 2015 May 21; 16:105. . View in PubMed

The role of DNA methylation in directing the functional organization of the cancer epigenome Genome Res. 2015 Apr; 25(4):467-77. . View in PubMed

Integrative analysis of 111 reference human epigenomes Nature. 2015 Feb 19; 518(7539):317-30. . View in PubMed

Intermediate DNA methylation is a conserved signature of genome regulation Nat Commun. 2015 Feb 18; 6:6363. . View in PubMed

Epigenetic and transcriptional determinants of the human breast Nat Commun. 2015 Feb 18; 6:6351. . View in PubMed

Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome Epigenetics Chromatin. 2015; 8:57. . View in PubMed

Demystifying the secret mission of enhancers: linking distal regulatory elements to target genes Crit Rev Biochem Mol Biol. 2015; 50(6):550-73. . View in PubMed

Altering cancer transcriptomes using epigenomic inhibitors Epigenetics Chromatin. 2015; 8:9. . View in PubMed

Regulatory network decoded from epigenomes of surface ectoderm-derived cell types Nat Commun. 2014 Nov 25; 5:5442. . View in PubMed

Functional annotation of colon cancer risk SNPs Nat Commun. 2014 Sep 30; 5:5114. . View in PubMed

Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes Genome Biol. 2014 Sep 20; 15(9):469. . View in PubMed

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33):E3366. . View in PubMed

Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha BMC Genomics. 2014 Jun 24; 15:520. . View in PubMed

Defining functional DNA elements in the human genome Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6131-8. . View in PubMed

Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation Nucleic Acids Res. 2014; 42(16):10856-68. . View in PubMed

Can genome engineering be used to target cancer-associated enhancers? Epigenomics. 2014; 6(5):493-501.. View in PubMed

Comprehensive functional annotation of 77 prostate cancer risk loci PLoS Genet. 2014 Jan; 10(1):e1004102. . View in PubMed

Cross-talk between site-specific transcription factors and DNA methylation states J Biol Chem. 2013 Nov 29; 288(48):34287-94. . View in PubMed

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros Nat Immunol. 2013 Oct; 14(10):1073-83. . View in PubMed

Recombinant antibodies to histone post-translational modifications Nat Methods. 2013 Oct; 10(10):992-5. . View in PubMed

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm Genome Res. 2013 Sep; 23(9):1522-40. . View in PubMed

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape Nat Genet. 2013 Jul; 45(7):836-41. . View in PubMed

ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes Epigenetics Chromatin. 2013 May 21; 6(1):13. . View in PubMed

LOcating non-unique matched tags (LONUT) to improve the detection of the enriched regions for ChIP-seq data PLoS One. 2013; 8(6):e67788. . View in PubMed

Spark: a navigational paradigm for genomic data exploration Genome Res. 2012 Nov; 22(11):2262-9. . View in PubMed

Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3 Genome Biol. 2012 Sep 26; 13(9):R52. . View in PubMed

Uncovering transcription factor modules using one- and three-dimensional analyses J Biol Chem. 2012 Sep 07; 287(37):30914-21. . View in PubMed

Thematic minireview series on results from the ENCODE Project: Integrative global analyses of regulatory regions in the human genome J Biol Chem. 2012 Sep 07; 287(37):30885-7. . View in PubMed

Architecture of the human regulatory network derived from ENCODE data Nature. 2012 Sep 06; 489(7414):91-100. . View in PubMed

An integrated encyclopedia of DNA elements in the human genome Nature. 2012 Sep 06; 489(7414):57-74. . View in PubMed

Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages Nucleic Acids Res. 2012 Sep; 40(16):7690-704. . View in PubMed

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia Genome Res. 2012 Sep; 22(9):1813-31. . View in PubMed

Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFß tumor suppressor signaling pathways Mol Cancer Res. 2012 Jul; 10(7):979-91. . View in PubMed

Using ChIPMotifs for de novo motif discovery of OCT4 and ZNF263 based on ChIP-based high-throughput experiments Methods Mol Biol. 2012; 802:323-34. . View in PubMed

Autophagy driven by a master regulator of hematopoiesis Mol Cell Biol. 2012 Jan; 32(1):226-39. . View in PubMed

The transcription factor encyclopedia Genome Biol. 2012; 13(3):R24. . View in PubMed

The Human Epigenome Browser at Washington University Nat Methods. 2011 Nov 29; 8(12):989-90. . View in PubMed

Genetic framework for GATA factor function in vascular biology Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13641-6. . View in PubMed

KAP1 protein: an enigmatic master regulator of the genome J Biol Chem. 2011 Jul 29; 286(30):26267-76. . View in PubMed

L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure Mol Cell. 2011 May 20; 42(4):438-50. . View in PubMed

Functional analysis of KAP1 genomic recruitment Mol Cell Biol. 2011 May; 31(9):1833-47. . View in PubMed

Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome J Biol Chem. 2011 Apr 08; 286(14):11985-96. . View in PubMed

A user's guide to the encyclopedia of DNA elements (ENCODE) PLoS Biol. 2011 Apr; 9(4):e1001046. . View in PubMed

Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes PLoS One. 2011 Feb 15; 6(2):e17121. . View in PubMed

Using ChIP-seq technology to generate high-resolution profiles of histone modifications Methods Mol Biol. 2011; 791:265-86. . View in PubMed

Transcription factor effector domains Subcell Biochem. 2011; 52:261-77. . View in PubMed

Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation PLoS One. 2011; 6(11):e27740. . View in PubMed

ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes PLoS One. 2010 Dec 08; 5(12):e15082. . View in PubMed

Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes BMC Genomics. 2010 Dec 02; 11:689. . View in PubMed

ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells Oncogene. 2010 Oct 07; 29(40):5500-10. . View in PubMed

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications Nat Biotechnol. 2010 Oct; 28(10):1097-105. . View in PubMed

The NIH Roadmap Epigenomics Mapping Consortium Nat Biotechnol. 2010 Oct; 28(10):1045-8. . View in PubMed

5-azacytidine treatment reorganizes genomic histone modification patterns Epigenetics. 2010 Apr; 5(3):229-40. . View in PubMed

Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263 J Biol Chem. 2010 Jan 08; 285(2):1393-403. . View in PubMed

Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data Nucleic Acids Res. 2010 Jan; 38(3):e13. . View in PubMed

Using ChIP-seq technology to identify targets of zinc finger transcription factors Methods Mol Biol. 2010; 649:437-55. . View in PubMed

W-ChIPMotifs: a web application tool for de novo motif discovery from ChIP-based high-throughput data Bioinformatics. 2009 Dec 01; 25(23):3191-3. . View in PubMed

Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy Mol Cell. 2009 Nov 25; 36(4):667-81. . View in PubMed

Insights from genomic profiling of transcription factors Nat Rev Genet. 2009 Sep; 10(9):605-16. . View in PubMed

N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor Cancer Res. 2008 Dec 01; 68(23):9654-62. . View in PubMed

E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites Genome Res. 2008 Nov; 18(11):1763-77. . View in PubMed

Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors Cancer Res. 2008 Apr 15; 68(8):2641-51. . View in PubMed

Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells Genome Res. 2008 Apr; 18(4):521-32. . View in PubMed

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets Genome Res. 2008 Mar; 18(3):393-403. . View in PubMed

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes Proc Natl Acad Sci U S A. 2007 Dec 04; 104(49):19416-21. . View in PubMed

Genome-scale ChIP-chip analysis using 10,000 human cells Biotechniques. 2007 Dec; 43(6):791-7. . View in PubMed

A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members Genome Res. 2007 Nov; 17(11):1550-61. . View in PubMed

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs Cell. 2007 Jun 29; 129(7):1311-23. . View in PubMed

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Nature. 2007 Jun 14; 447(7146):799-816. . View in PubMed

Identification of an OCT4 and SRY regulatory module using integrated computational and experimental genomics approaches Genome Res. 2007 Jun; 17(6):807-17. . View in PubMed

Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs PLoS Genet. 2007 Jun; 3(6):e89. . View in PubMed

Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays J Biol Chem. 2007 Mar 30; 282(13):9703-9712. . View in PubMed

A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data--a case study using E2F1 Genome Res. 2006 Dec; 16(12):1585-95. . View in PubMed

Locating mammalian transcription factor binding sites: a survey of computational and experimental techniques Genome Res. 2006 Dec; 16(12):1455-64. . View in PubMed

Comparison of sample preparation methods for ChIP-chip assays Biotechniques. 2006 Nov; 41(5):577-80. . View in PubMed

Suz12 binds to silenced regions of the genome in a cell-type-specific manner Genome Res. 2006 Jul; 16(7):890-900. . View in PubMed

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome Genome Res. 2006 May; 16(5):595-605. . View in PubMed

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):1859-64. . View in PubMed

CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome Nucleic Acids Res. 2005; 33(9):2952-61. . View in PubMed

The use of transient chromatin immunoprecipitation assays to test models for E2F1-specific transcriptional activation J Biol Chem. 2004 Oct 29; 279(44):46343-9. . View in PubMed

Genomic approaches that aid in the identification of transcription factor target genes Exp Biol Med (Maywood). 2004 Sep; 229(8):705-21. . View in PubMed

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27 Genes Dev. 2004 Jul 01; 18(13):1592-605. . View in PubMed

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells Immunity. 2004 Apr; 20(4):477-94. . View in PubMed

High-throughput screening of chromatin immunoprecipitates using CpG-island microarrays Methods Enzymol. 2004; 376:315-34. . View in PubMed

E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9 J Biol Chem. 2003 Oct 24; 278(43):42466-76. . View in PubMed

Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression Curr Biol. 2003 May 13; 13(10):882-6. . View in PubMed

Identification and characterization of CRG-L2, a new marker for liver tumor development Oncogene. 2003 Mar 20; 22(11):1730-6. . View in PubMed

Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase Oncogene. 2003 Mar 13; 22(10):1445-60. . View in PubMed

Probing chromatin immunoprecipitates with CpG-island microarrays to identify genomic sites occupied by DNA-binding proteins Methods Enzymol. 2003; 371:577-96. . View in PubMed

Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy Mol Cancer Ther. 2003 Jan; 2(1):113-21. . View in PubMed

Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter J Biol Chem. 2002 Oct 18; 277(42):40156-62. . View in PubMed

The identification of E2F1-specific target genes Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3890-5. . View in PubMed

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis Genes Dev. 2002 Jan 15; 16(2):235-44. . View in PubMed

c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism J Biol Chem. 2001 Dec 21; 276(51):48562-71. . View in PubMed

Use of chromatin immunoprecipitation to clone novel E2F target promoters Mol Cell Biol. 2001 Oct; 21(20):6820-32. . View in PubMed

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis Mol Cell Biol. 2001 Sep; 21(17):6006-16. . View in PubMed

The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements J Biol Chem. 2001 Jun 08; 276(23):20482-90. . View in PubMed

Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors J Mol Biol. 2001 May 25; 309(1):99-120. . View in PubMed

Expression profiling and identification of novel genes in hepatocellular carcinomas Oncogene. 2001 May 10; 20(21):2704-12. . View in PubMed

Direct examination of histone acetylation on Myc target genes using chromatin immunoprecipitation J Biol Chem. 2000 Oct 27; 275(43):33798-805. . View in PubMed

Direct recruitment of N-myc to target gene promoters Mol Carcinog. 2000 Oct; 29(2):76-86. . View in PubMed

Target gene specificity of E2F and pocket protein family members in living cells Mol Cell Biol. 2000 Aug; 20(16):5797-807. . View in PubMed

Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation Oncogene. 2000 Apr 27; 19(18):2257-68. . View in PubMed

CAD, a c-Myc target gene, is not deregulated in Burkitt's lymphoma cell lines Mol Carcinog. 2000 Feb; 27(2):84-96. . View in PubMed

Coexamination of site-specific transcription factor binding and promoter activity in living cells Mol Cell Biol. 1999 Dec; 19(12):8393-9. . View in PubMed

Context-dependent transcriptional regulation J Biol Chem. 1999 Oct 15; 274(42):29583-6. . View in PubMed

Identification of target genes of oncogenic transcription factors Proc Soc Exp Biol Med. 1999 Oct; 222(1):9-28. . View in PubMed

No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice Mol Carcinog. 1999 Aug; 25(4):295-303. . View in PubMed

Activation of the murine dihydrofolate reductase promoter by E2F1A requirement for CBP recruitment. J Biol Chem. 1999 May 28; 274(22):15883-91. . View in PubMed

Characterization of the 3' untranslated region of mouse E2F1 mRNA Gene. 1998 Nov 26; 223(1-2):355-60. . View in PubMed

c-Myc target gene specificity is determined by a post-DNAbinding mechanism Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13887-92. . View in PubMed

E2F-mediated growth regulation requires transcription factor cooperation J Biol Chem. 1997 Jul 18; 272(29):18367-74. . View in PubMed

Myc versus USF: discrimination at the cad gene is determined by core promoter elements Mol Cell Biol. 1997 May; 17(5):2529-37. . View in PubMed

Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain Mol Cell Biol. 1997 Apr; 17(4):1966-76. . View in PubMed

Conclusions and future directions Curr Top Microbiol Immunol. 1996; 208:129-37. . View in PubMed

Introduction to the E2F family: protein structure and gene regulation Curr Top Microbiol Immunol. 1996; 208:1-30. . View in PubMed

Transcriptional regulation of the dihydrofolate reductase gene Bioessays. 1996 Jan; 18(1):55-62. . View in PubMed

Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice Mol Carcinog. 1995 Sep; 14(1):46-52. . View in PubMed

The bidirectionally transcribed dihydrofolate reductase and rep-3a promoters are growth regulated by distinct mechanisms Cell Growth Differ. 1995 May; 6(5):541-8. . View in PubMed

v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1 Cell Growth Differ. 1995 May; 6(5):549-56. . View in PubMed

An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants Mol Cell Biol. 1995 May; 15(5):2527-35. . View in PubMed

Identification of cis-acting elements that can obviate a requirement for the C-terminal domain of RNA polymerase II J Biol Chem. 1995 Mar 24; 270(12):6798-807. . View in PubMed

Inappropriate transcription from the 5' end of the murine dihydrofolate reductase gene masks transcriptional regulation Nucleic Acids Res. 1994 Aug 11; 22(15):3061-8. . View in PubMed

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter Genes Dev. 1994 Jul 01; 8(13):1526-37. . View in PubMed

Cloning, chromosomal location, and characterization of mouse E2F1 Mol Cell Biol. 1994 Mar; 14(3):1861-9. . View in PubMed

Start site selection at the TATA-less carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter J Biol Chem. 1994 Jan 21; 269(3):2252-7. . View in PubMed

Transcriptional regulation of the dihydrofolate reductase/rep-3 locus Crit Rev Eukaryot Gene Expr. 1994; 4(1):19-53. . View in PubMed

The role of E2F in the mammalian cell cycle Biochim Biophys Acta. 1993 Aug 23; 1155(2):125-31. . View in PubMed

An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes J Biol Chem. 1993 Jul 25; 268(21):15674-80. . View in PubMed

Site-specific initiation of transcription by RNA polymerase II Proc Soc Exp Biol Med. 1993 Jun; 203(2):127-39. . View in PubMed

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter Mol Cell Biol. 1993 Mar; 13(3):1610-8. . View in PubMed

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties Cell. 1992 Jul 24; 70(2):351-64. . View in PubMed

krox 20 messenger RNA and protein expression in the adult central nervous system Brain Res Mol Brain Res. 1992 Jun; 14(1-2):117-23. . View in PubMed

The HIP1 initiator element plays a role in determining the in vitro requirement of the dihydrofolate reductase gene promoter for the C-terminal domain of RNA polymerase II Mol Cell Biol. 1992 May; 12(5):2250-9. . View in PubMed

The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter Mol Cell Biol. 1992 Mar; 12(3):1054-63. . View in PubMed

Heat sensitivity and Sp1 activation of complex formation at the Syrian hamster carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter in vitro J Biol Chem. 1992 Jan 05; 267(1):385-91. . View in PubMed

Cell cycle analysis of Krox-20, c-fos, and JE expression in proliferating NIH3T3 fibroblasts Cell Growth Differ. 1991 Sep; 2(9):465-73. . View in PubMed

Sp1 activation of RNA polymerase II transcription complexes involves a heat-labile DNA-binding component Gene Expr. 1991 May; 1(2):137-48. . View in PubMed

Identification of the serum-responsive transcription initiation site of the zinc finger gene Krox-20 Mol Cell Biol. 1990 Jul; 10(7):3788-91. . View in PubMed

Sequences downstream of the transcription initiation site modulate the activity of the murine dihydrofolate reductase promoter Mol Cell Biol. 1990 Apr; 10(4):1390-8. . View in PubMed

Characterization of the 5' end of the growth-regulated Syrian hamster CAD gene Cell Growth Differ. 1990 Apr; 1(4):179-89. . View in PubMed

Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site Mol Cell Biol. 1990 Feb; 10(2):653-61. . View in PubMed

Identification of a new promoter upstream of the murine dihydrofolate reductase gene Mol Cell Biol. 1989 Oct; 9(10):4568-70. . View in PubMed

In vitro transcription and delimitation of promoter elements of the murine dihydrofolate reductase gene Mol Cell Biol. 1986 Jul; 6(7):2392-401. . View in PubMed

Murine dihydrofolate reductase transcripts through the cell cycle Mol Cell Biol. 1986 Feb; 6(2):365-71. . View in PubMed

Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle J Biol Chem. 1985 Jun 25; 260(12):7675-80. . View in PubMed

Opposite-strand RNAs from the 5' flanking region of the mouse dihydrofolate reductase gene Proc Natl Acad Sci U S A. 1985 Jun; 82(12):3978-82. . View in PubMed

Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAsEvidence for multiple promoter regions. J Biol Chem. 1985 Feb 25; 260(4):2307-14. . View in PubMed

Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell line Proc Natl Acad Sci U S A. 1985 Feb; 82(4):1126-30. . View in PubMed

Effects of NusA protein on transcription termination in the tryptophan operon of Escherichia coli Cell. 1982 Jul; 29(3):945-51. . View in PubMed

Effects of DNA base analogs on transcription termination at the tryptophan operon attenuator of EScherichia coli Proc Natl Acad Sci U S A. 1982 Feb; 79(4):998-1002. . View in PubMed

Synthetic sites for transcription termination and a functional comparison with tryptophan operon termination sites in vitro Proc Natl Acad Sci U S A. 1981 Jul; 78(7):4180-4. . View in PubMed

Rho-independent termination: dyad symmetry in DNA causes RNA polymerase to pause during transcription in vitro Nucleic Acids Res. 1981 Feb 11; 9(3):563-77. . View in PubMed

A model for transcription termination suggested by studies on the trp attenuator in vitro using base analogs Cell. 1980 Jul; 20(3):739-48. . View in PubMed

Effects of gentamicin on trypsin, chymotrypsin, and collagenase J Infect Dis. 1978 Aug; 138(2):257-9. . View in PubMed

A re-examination of the distributions of octopamine and phenylethanolamine in the aplysia nervous system J Neurochem. 1978 May; 30(5):1173-6. . View in PubMed