Keck School Faculty

Peter Stephen Conti

Peter Stephen Conti

Professor of Radiology
Director, Molecular Imaging Center
PET Imaging Center Director
Radiology
CSC 103 Health Sciences Campus Los Angeles

18FDG-PET/CT Specificity for the Detection of Lymphoma Recurrence in the Tonsils OTO Open. 2021 Oct-Dec; 5(4):2473974X211059081. . View in PubMed

Exploring Solvent Effects in the Radiosynthesis of 18F-Labeled Thymidine Analogues toward Clinical Translation for Positron Emission Tomography Imaging ACS Pharmacol Transl Sci. 2021 Feb 12; 4(1):266-275. . View in PubMed

Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan Nat Metab. 2021 10; 3(10):1342-1356. . View in PubMed

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed

Recent advances in the development of nanoparticles for multimodality imaging and therapy of cancer Med Res Rev. 2020 05; 40(3):909-930. . View in PubMed

Radiofluorinated GPC3-Binding Peptides for PET Imaging of Hepatocellular Carcinoma Mol Imaging Biol. 2020 02; 22(1):134-143. . View in PubMed

Associations between Vascular Function and Tau PET Are Associated with Global Cognition and Amyloid J Neurosci. 2020 10 28; 40(44):8573-8586. . View in PubMed

A Pre-clinical Animal Model of Secondary Head and Neck Lymphedema Sci Rep. 2019 12 04; 9(1):18264. . View in PubMed

Developing Effective Alzheimer's Disease Therapies: Clinical Experience and Future Directions J Alzheimers Dis. 2019; 71(3):715-732. . View in PubMed

Small molecules as theranostic agents in cancer immunology Theranostics. 2019; 9(25):7849-7871. . View in PubMed

PET Imaging of Adenosine Receptors in Diseases Curr Top Med Chem. 2019; 19(16):1445-1463. . View in PubMed

Polyethyleneimine-Coated Manganese Oxide Nanoparticles for Targeted Tumor PET/MR Imaging ACS Appl Mater Interfaces. 2018 Oct 17; 10(41):34954-34964. . View in PubMed

PET imaging of Hsp90 expression in pancreatic cancer using a new 64Cu-labeled dimeric Sansalvamide A decapeptide Amino Acids. 2018 Jul; 50(7):897-907. . View in PubMed

64Cu-Labeled multifunctional dendrimers for targeted tumor PET imaging Nanoscale. 2018 Mar 29; 10(13):6113-6124. . View in PubMed

Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis J Clin Invest. 2018 03 01; 128(3):970-984. . View in PubMed

Effect of Androgen on Normal Biodistribution of [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in Athymic Non-tumor-bearing Male Mice Anticancer Res. 2017 02; 37(2):475-479. . View in PubMed

A Nanoscale Tool for Photoacoustic-Based Measurements of Clotting Time and Therapeutic Drug Monitoring of Heparin Nano Lett. 2016 Oct 12; 16(10):6265-6271. . View in PubMed

A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice Int J Cancer. 2016 Feb 15; 138(4):1013-23. . View in PubMed

In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes Methods Mol Biol. 2016; 1444:73-84. . View in PubMed

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan Cell Metab. 2015 Jul 07; 22(1):86-99. . View in PubMed

Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159 J Nucl Med. 2015 Jun; 56(6):908-13. . View in PubMed

One-Year Postapproval Clinical Experience with Radium-223 Dichloride in Patients with Metastatic Castrate-Resistant Prostate Cancer Cancer Biother Radiopharm. 2015 Jun; 30(5):195-9. . View in PubMed

Walter Wolf, PhD, 1931-2014 J Nucl Med. 2015 May; 56(5):13N18N. . View in PubMed

Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation Bioconjug Chem. 2015 Mar 18; 26(3):435-42. . View in PubMed

Sodium 18F-fluoride PET/CT of bone, joint, and other disorders Semin Nucl Med. 2015 Jan; 45(1):58-65. . View in PubMed

Development of PET probes for cancer imaging Curr Top Med Chem. 2015; 15(8):795-819. . View in PubMed

In vivo NIRF imaging-guided delivery of a novel NGR-VEGI fusion protein for targeting tumor vasculature Amino Acids. 2014 Dec; 46(12):2721-32. . View in PubMed

Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft Mol Pharm. 2014 Nov 03; 11(11):3974-9. . View in PubMed

MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage Mol Pharm. 2014 Nov 03; 11(11):3938-46. . View in PubMed

Integrin a2ß1 targeted GdVO4:Eu ultrathin nanosheet for multimodal PET/MR imaging Biomaterials. 2014 Oct; 35(30):8649-58. . View in PubMed

Characterization and evaluation of (64)Cu-labeled A20FMDV2 conjugates for imaging the integrin avß 6 Mol Imaging Biol. 2014 Aug; 16(4):567-77. . View in PubMed

Axl-targeted cancer imaging with humanized antibody h173 Mol Imaging Biol. 2014 Aug; 16(4):511-8. . View in PubMed

Multimeric disintegrin protein polymer fusions that target tumor vasculature Biomacromolecules. 2014 Jul 14; 15(7):2347-58. . View in PubMed

Efficient synthesis of fluorescent-PET probes based on [¹8F]BODIPY dye Chem Commun (Camb). 2014 Jul 14; 50(55):7371-3. . View in PubMed

The synthesis of lanthanide-doped GdVO4 ultrathin nanosheets with great optical and paramagnetic properties for FRET biodetection and in vivo MR imaging J Mater Chem B. 2014 Jul 07; 2(25):3998-4007. . View in PubMed

Facile Preparation of a Thiol-Reactive (18)F-Labeling Agent and Synthesis of (18)F-DEG-VS-NT for PET Imaging of a Neurotensin Receptor-Positive Tumor J Nucl Med. 2014 Jul; 55(7):1178-84. . View in PubMed

Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy55-labeled dimeric NGR peptide. Amino Acids. 2014 Jun; 46(6):1547-56. . View in PubMed

Development of multi-functional chelators based on sarcophagine cages Molecules. 2014 Apr 03; 19(4):4246-55. . View in PubMed

Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide Biomaterials. 2014 Apr; 35(13):4082-7. . View in PubMed

Patlak image estimation from dual time-point list-mode PET data IEEE Trans Med Imaging. 2014 Apr; 33(4):913-24. . View in PubMed

A hybrid protein-polymer nanoworm potentiates apoptosis better than a monoclonal antibody ACS Nano. 2014 Mar 25; 8(3):2064-76. . View in PubMed

Radiolabeled nanoparticles for multimodality tumor imaging Theranostics. 2014; 4(3):290-306. . View in PubMed

Functional imaging of human epidermal growth factor receptor 2-positive metastatic breast cancer using (64)Cu-DOTA-trastuzumab PET J Nucl Med. 2014 Jan; 55(1):23-9. . View in PubMed

Sparsity Constrained Mixture Modeling for the Estimation of Kinetic Parameters in Dynamic PET IEEE Trans Med Imaging. 2014 Jan; 33(1):173-85. . View in PubMed

Evaluation of ¹8F-labeled BODIPY dye as potential PET agents for myocardial perfusion imaging Nucl Med Biol. 2014 Jan; 41(1):120-6. . View in PubMed

(64)Cu labeled sarcophagine exendin-4 for microPET imaging of glucagon like peptide-1 receptor expression Theranostics. 2014; 4(8):770-7. . View in PubMed

Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis Clin Cancer Res. 2013 Dec 15; 19(24):6802-11. . View in PubMed

EphB4-targeted imaging with antibody h131, h131-F(ab')2 and h131-Fab Mol Pharm. 2013 Dec 02; 10(12):4527-33. . View in PubMed

Cytoreductive chemotherapy improves the biodistribution of antibodies directed against tumor necrosis in murine solid tumor models Mol Cancer Ther. 2013 Dec; 12(12):2827-36. . View in PubMed

Tumor quantification in clinical positron emission tomography Theranostics. 2013 Oct 07; 3(10):787-801. . View in PubMed

Baseline 18F-FDG PET/CT parameters as imaging biomarkers of overall survival in castrate-resistant metastatic prostate cancer J Nucl Med. 2013 Aug; 54(8):1195-201. . View in PubMed

PET imaging of colorectal and breast cancer by targeting EphB4 receptor with 64Cu-labeled hAb47 and hAb131 antibodies J Nucl Med. 2013 Jul; 54(7):1094-100. . View in PubMed

RGD-based PET tracers for imaging receptor integrin av ß3 expression J Labelled Comp Radiopharm. 2013 May 15; 56(5):264-79. . View in PubMed

Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs Biomaterials. 2013 Apr; 34(12):3098-109. . View in PubMed

Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation Mol Imaging. 2013 Mar-Apr; 12(2):121-8. . View in PubMed

Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets J Nucl Med. 2013 Feb; 54(2):244-51. . View in PubMed

Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for MicroPET imaging of CD13 receptor expression Mol Pharm. 2013 Jan 07; 10(1):417-27. . View in PubMed

Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring Mol Pharm. 2013 Jan 07; 10(1):329-36. . View in PubMed

Kinetic quantification of protein polymer nanoparticles using non-invasive imaging Integr Biol (Camb). 2013 Jan; 5(1):183-94. . View in PubMed

Urokinase plasminogen activator receptor (uPAR) targeted nuclear imaging and radionuclide therapy Theranostics. 2013; 3(7):507-15. . View in PubMed

Lewis acid-assisted isotopic 18F-19F exchange in BODIPY dyes: facile generation of positron emission tomography/fluorescence dual modality agents for tumor imaging Theranostics. 2013; 3(3):181-9. . View in PubMed

"Kit like" (18)F labeling method for synthesis of RGD peptide-based PET probes Am J Nucl Med Mol Imaging. 2013; 3(1):97-101. . View in PubMed

Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of (64)Cu-Labeled PET Imaging Probes ACS Med Chem Lett. 2012 Dec 13; 3(12):1019-23. . View in PubMed

Efficient construction of PET/fluorescence probe based on sarcophagine cage: an opportunity to integrate diagnosis with treatment Mol Imaging Biol. 2012 Dec; 14(6):718-24. . View in PubMed

Radioactive smart probe for potential corrected matrix metalloproteinase imaging Bioconjug Chem. 2012 Nov 21; 23(11):2159-67. . View in PubMed

Microwave-assisted one-pot radiosynthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-d-arabinofuranosyluracil ([18F]-FMAU) Nucl Med Biol. 2012 Oct; 39(7):1019-25. . View in PubMed

[18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in prostate cancer: initial preclinical observations Mol Imaging. 2012 Sep-Oct; 11(5):426-32. . View in PubMed

Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells Ann Rheum Dis. 2012 Sep; 71(9):1567-1572. . View in PubMed

Inhibition of P-glycoprotein-mediated transport by S-adenosylmethionine and cynarin in multidrug-resistant human uterine sarcoma MES-SA/Dx5 cells J Biol Regul Homeost Agents. 2012 Jul-Sep; 26(3):495-504. . View in PubMed

Prospective evaluation of 18F-NaF and 18F-FDG PET/CT in detection of occult metastatic disease in biochemical recurrence of prostate cancer Clin Nucl Med. 2012 Jul; 37(7):637-43. . View in PubMed

ß-adrenergic receptor inhibition affects cerebral glucose metabolism, motor performance, and inflammatory response after traumatic brain injury J Trauma Acute Care Surg. 2012 Jul; 73(1):33-40. . View in PubMed

Quantitative, simultaneous PET/MRI for intratumoral imaging with an MRI-compatible PET scanner J Nucl Med. 2012 Jul; 53(7):1102-9. . View in PubMed

A Cy55-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice. Amino Acids. 2012 Apr; 42(4):1329-37. . View in PubMed

A potentially common peptide target in secreted heat shock protein-90a for hypoxia-inducible factor-1a-positive tumors Mol Biol Cell. 2012 Feb; 23(4):602-13. . View in PubMed

Evaluation of 64Cu labeled GX1: a phage display peptide probe for PET imaging of tumor vasculature Mol Imaging Biol. 2012 Feb; 14(1):96-105. . View in PubMed

The efficient synthesis and biological evaluation of novel bi-functionalized sarcophagine for (64)cu radiopharmaceuticals Theranostics. 2012; 2(6):589-96. . View in PubMed

PET imaging of metabotropic glutamate receptor subtype 5 (mGluR5) Am J Nucl Med Mol Imaging. 2012; 2(1):29-32. . View in PubMed

Fasting enhances the response of glioma to chemo- and radiotherapy PLoS One. 2012; 7(9):e44603. . View in PubMed

In vivo near-infrared fluorescence imaging of integrin a2ß1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe J Nucl Med. 2011 Dec; 52(12):1979-86. . View in PubMed

Rapid aqueous [18F]-labeling of a bodipy dye for positron emission tomography/fluorescence dual modality imaging Chem Commun (Camb). 2011 Sep 07; 47(33):9324-6. . View in PubMed

Efficient preparation and biological evaluation of a novel multivalency bifunctional chelator for 64Cu radiopharmaceuticals Chemistry. 2011 Sep 05; 17(37):10222-5. . View in PubMed

Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin avß3 targeted PET tracer based on a cyclic RGD peptide Bioorg Med Chem Lett. 2011 Sep 01; 21(17):5011-4. . View in PubMed

Novel a(2)ß(1) integrin-targeted peptide probes for prostate cancer imaging Mol Imaging. 2011 Aug; 10(4):284-94. . View in PubMed

Design, synthesis and validation of integrin a2ß1-targeted probe for microPET imaging of prostate cancer Eur J Nucl Med Mol Imaging. 2011 Jul; 38(7):1313-22. . View in PubMed

The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy Nucl Med Biol. 2011 Jul; 38(5):659-66. . View in PubMed

SNM clinical trials network validates 100th scanner J Nucl Med. 2011 Jun; 52(6):25N. . View in PubMed

18F-5-fluorouracil dynamic positron emission tomography/computed tomography shows decreased tracer activity after bevacizumab in colorectal metastases Nucl Med Commun. 2011 May; 32(5):343-7. . View in PubMed

Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer Eur J Nucl Med Mol Imaging. 2011 Apr; 38(4):642-50. . View in PubMed

Biological stability evaluation of the a2ß1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide Bioconjug Chem. 2011 Feb 16; 22(2):256-63. . View in PubMed

Automated synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-D-arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module Nucl Med Biol. 2011 Feb; 38(2):201-6. . View in PubMed

Improved synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-D-arabinofuranosyluracil ([18F]FMAU) Curr Radiopharm. 2011 Jan; 4(1):24-30. . View in PubMed

Trackable and Targeted Phage as Positron Emission Tomography (PET) Agent for Cancer Imaging Theranostics. 2011; 1:371-80. . View in PubMed

(64)Cu labeled AmBaSar-RGD2 for micro-PET imaging of integrin avß3 expression Curr Radiopharm. 2011 Jan; 4(1):68-74. . View in PubMed

Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes Chem Commun (Camb). 2010 Nov 14; 46(42):8043-5. . View in PubMed

Clinical trials network strives for standardization J Nucl Med. 2010 Nov; 51(11):15N. . View in PubMed

Target-specific delivery of peptide-based probes for PET imaging Adv Drug Deliv Rev. 2010 Aug 30; 62(11):1005-22. . View in PubMed

Radiopharmaceutical chemistry for positron emission tomography Adv Drug Deliv Rev. 2010 Aug 30; 62(11):1031-51. . View in PubMed

Evaluation of copper-64 labeled AmBaSar conjugated cyclic RGD peptide for improved microPET imaging of integrin alphavbeta3 expression Bioconjug Chem. 2010 Aug 18; 21(8):1417-24. . View in PubMed

The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition J Biol Chem. 2010 Aug 06; 285(32):24432-8. . View in PubMed

Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin- resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy J Biol Regul Homeost Agents. 2010 Apr-Jun; 24(2):197-205. . View in PubMed

In vivo effect of propranolol dose and timing on cerebral perfusion after traumatic brain injury J Trauma. 2010 Feb; 68(2):353-6. . View in PubMed

An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[66. 6]icosane-1-ylamino)methyl)benzoic acid, for 64Cu radiopharmaceuticals. Nucl Med Biol. 2010 Jan; 37(1):57-65. . View in PubMed

Controlling familywise error rate for matched subspace detection in dynamic FDG PET IEEE Trans Med Imaging. 2009 Oct; 28(10):1623-31. . View in PubMed

Site qualification in multicenter clinical trials J Nucl Med. 2009 Aug; 50(8):30N. . View in PubMed

Synthesis of a novel bifunctional chelator AmBaSar based on sarcophagine for peptide conjugation and (64)Cu radiolabelling Dalton Trans. 2009 Jul 21; (27):5395-400. . View in PubMed

SNM molecular imaging summit introduces clinical trials network J Nucl Med. 2009 Apr; 50(4):18N. . View in PubMed

Lesion detection in dynamic FDG-PET using matched subspace detection IEEE Trans Med Imaging. 2009 Feb; 28(2):230-40. . View in PubMed

The in vivo effect of propranolol on cerebral perfusion and hypoxia after traumatic brain injury J Trauma. 2009 Jan; 66(1):154-9; discussion 159-61. . View in PubMed

Expert opinions on positron emission tomography and computed tomography imaging in lymphoma Oncologist. 2009; 14 Suppl 2:30-40. . View in PubMed

New directions in the therapeutic strategy to improve survival outcomes in patients with non-Hodgkin's lymphomaIntroduction. Oncologist. 2009; 14 Suppl 2:1-3. . View in PubMed

New directions in the therapeutic strategy to improve survival outcomes in patients with non-Hodgkin's lymphomaSummary. Oncologist. 2009; 14 Suppl 2:52-4. . View in PubMed

[F-18]-fluorodeoxyglucose PET-CT of the normal prostate gland Ann Nucl Med. 2008 Nov; 22(9):787-93. . View in PubMed

Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine Brain Res. 2008 Oct 09; 1234:32-43. . View in PubMed

Biglycan overexpression on tooth enamel formation in transgenic mice Anat Rec (Hoboken). 2008 Oct; 291(10):1246-53. . View in PubMed

Molecular imaging: the future of modern medicine J Nucl Med. 2008 Jun; 49(6):16N-20N. . View in PubMed

Choline autoradiography of human prostate cancer xenograft: effect of castration Mol Imaging. 2008 May-Jun; 7(3):147-52. . View in PubMed

A new diagnostic approach to better identify antiphospholipid syndrome Int J Immunopathol Pharmacol. 2008 Apr-Jun; 21(2):387-92. . View in PubMed

B-cell non-Hodgkin lymphoma: PET/CT evaluation after 90Y-ibritumomab tiuxetan radioimmunotherapy--initial experience Radiology. 2008 Mar; 246(3):895-902. . View in PubMed

[F-18]-Fluorodeoxyglucose PET and PET-CT in diagnostic imaging evaluation of locally recurrent and metastatic bladder transitional cell carcinoma Int J Clin Oncol. 2008 Feb; 13(1):42-7. . View in PubMed

How do rat cortical cells cultured with aluminum die: necrosis or apoptosis? Int J Immunopathol Pharmacol. 2008 Jan-Mar; 21(1):107-15.. View in PubMed

In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET Nucl Med Biol. 2008 Jan; 35(1):131-41. . View in PubMed

F-18 FDG PET and PET/CT evaluation of response to chemotherapy in bone and soft tissue sarcomas Clin Nucl Med. 2008 Jan; 33(1):8-13. . View in PubMed

Neuroendocrine immunophenotype as predictor of clinical recurrence in 110 patients with prostate cancer Int J Immunopathol Pharmacol. 2007 Oct-Dec; 20(4):765-70. . View in PubMed

Morphostructural analysis of human follicular stem cells on highly porous bone hydroxyapatite scaffold Int J Immunopathol Pharmacol. 2007 Oct-Dec; 20(4):819-26. . View in PubMed

Weight-based dosing of Yttrium 90 ibritumomab tiuxetan in patients with relapsed or refractory B-cell non-Hodgkin lymphoma Clin Lymphoma Myeloma. 2007 Sep; 7(8):514-7. . View in PubMed

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence Cancer Res. 2007 Aug 01; 67(15):7525-33. . View in PubMed

In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression Eur J Nucl Med Mol Imaging. 2007 Jun; 34(6):822-9. . View in PubMed

Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives Nucl Med Biol. 2007 Apr; 34(3):267-72. . View in PubMed

Detection of occult medullary thyroid cancer recurrence with 2-deoxy-2-[F-18]fluoro-D-glucose-PET and PET/CT Mol Imaging Biol. 2007 Mar-Apr; 9(2):72-7. . View in PubMed

[F-18]fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma J Comput Assist Tomogr. 2007 Mar-Apr; 31(2):223-8. . View in PubMed

Breast MRI and 18F FDG PET/CT in the management of breast cancer Ann Nucl Med. 2007 Jan; 21(1):33-8. . View in PubMed

Assessment of three year experience of a strategy for patient selection and timing of operation in the management of acute thoracic and lumbar spine fractures: a prospective study Acta Neurochir (Wien). 2006 Nov; 148(11):1181-7; discussion 1187. . View in PubMed

18F-FDG PET and PET/CT for detection of pulmonary metastases from musculoskeletal sarcomas Nucl Med Commun. 2006 Oct; 27(10):795-802. . View in PubMed

2-Deoxy-2-[18F]fluoro-D-glucose-positron emission tomography and positron emission tomography/computed tomography diagnosis of patients with recurrent papillary thyroid cancer Mol Imaging Biol. 2006 Sep-Oct; 8(5):309-14. . View in PubMed

Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice Cancer Res. 2006 Sep 01; 66(17):8430-8. . View in PubMed

2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography/computed tomography imaging evaluation of esophageal cancer Mol Imaging Biol. 2006 May-Jun; 8(3):193-200. . View in PubMed

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide Mol Imaging Biol. 2006 Jan-Feb; 8(1):9-15. . View in PubMed

Interleukin -1beta (IL-1 beta), interleukin 6 (IL-6) and tumor necrosis factor (TNF) in plasma and pleural fluid of pneumonia, lung cancer and tuberculous pleuritis J Biol Regul Homeost Agents. 2006 Jan-Jun; 20(1-2):41-6. . View in PubMed

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging Phys Med Biol. 2005 Dec 07; 50(23):5421-41. . View in PubMed

The role of imaging with (111)In-ibritumomab tiuxetan in the ibritumomab tiuxetan (zevalin) regimen: results from a Zevalin Imaging Registry J Nucl Med. 2005 Nov; 46(11):1812-8. . View in PubMed

Concurrent PET/CT with an integrated imaging system: intersociety dialogue from the Joint Working Group of the American College of Radiology, the Society of Nuclear Medicine, and the Society of Computed Body Tomography and Magnetic Resonance J Am Coll Radiol. 2005 Jul; 2(7):568-84. . View in PubMed

Concurrent PET/CT with an integrated imaging system: intersociety dialogue from the joint working group of the American College of Radiology, the Society of Nuclear Medicine, and the Society of Computed Body Tomography and Magnetic Resonance J Nucl Med. 2005 Jul; 46(7):1225-39. . View in PubMed

Glucose metabolism of human prostate cancer mouse xenografts Mol Imaging. 2005 Apr-Jun; 4(2):91-7. . View in PubMed

Integrin alpha v beta 3-targeted imaging of lung cancer Neoplasia. 2005 Mar; 7(3):271-9. . View in PubMed

The future of radioimmunotherapy: a PET perspective Semin Oncol. 2005 Feb; 32(1 Suppl 1):S63-7. . View in PubMed

Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression J Nucl Med. 2004 Dec; 45(12):2063-9. . View in PubMed

Virchow's node on F-18 FDG PET/CT Clin Nucl Med. 2004 Nov; 29(11):770-2. . View in PubMed

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts Cancer Res. 2004 Nov 01; 64(21):8009-14. . View in PubMed

Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression J Nucl Med. 2004 Oct; 45(10):1776-83. . View in PubMed

Musculoskeletal system Semin Nucl Med. 2004 Oct; 34(4):254-61. . View in PubMed

The reproductive tract Semin Nucl Med. 2004 Oct; 34(4):262-73. . View in PubMed

MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides Mol Imaging Biol. 2004 Sep-Oct; 6(5):350-9. . View in PubMed

MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide Eur J Nucl Med Mol Imaging. 2004 Aug; 31(8):1081-9. . View in PubMed

microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts J Nucl Med. 2004 Aug; 45(8):1390-7. . View in PubMed

Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression Nucl Med Biol. 2004 May; 31(4):399-405. . View in PubMed

Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats Nucl Med Biol. 2004 May; 31(4):407-18. . View in PubMed

Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model Mol Imaging. 2004 Apr; 3(2):76-84. . View in PubMed

Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide Mol Imaging. 2004 Apr; 3(2):96-104. . View in PubMed

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis Nucl Med Biol. 2004 Feb; 31(2):179-89. . View in PubMed

Radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin): the role of the nuclear medicine physician Semin Nucl Med. 2004 Jan; 34(1 Suppl 1):2-3. . View in PubMed

Interleukin-17: a revisited study Int J Immunopathol Pharmacol. 2004 Jan-Apr; 17(1):1-4. . View in PubMed

MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide Bioconjug Chem. 2004 Jan-Feb; 15(1):41-9. . View in PubMed

Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation Nucl Med Biol. 2004 Jan; 31(1):11-9. . View in PubMed

Diagnostic role of [F-18]-FDG positron emission tomography in restaging renal cell carcinoma Clin Nephrol. 2003 Dec; 60(6):395-400. . View in PubMed

Interleukin-25 (or IL-17E): a new IL-17 family member with growth factor/inflammatory actions Int J Immunopathol Pharmacol. 2003 Sep-Dec; 16(3):185-8. . View in PubMed

FDG PET in suspected recurrent and metastatic prostate cancer Oncol Rep. 2003 Sep-Oct; 10(5):1485-8. . View in PubMed

Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats Cancer Res. 2003 Jul 01; 63(13):3667-74. . View in PubMed

Receptor mediated uptake of a radiolabeled contrast agent sensitive to beta-galactosidase activity Nucl Med Biol. 2003 Apr; 30(3):261-5. . View in PubMed

Evaluation of recurrent gastric malignancy with [F-18]-FDG positron emission tomography Clin Radiol. 2003 Mar; 58(3):215-21. . View in PubMed

Diagnostic utility of FDG PET in multiple myeloma Skeletal Radiol. 2002 Dec; 31(12):690-4. . View in PubMed

Incidental colonic fluorodeoxyglucose uptake: correlation with colonoscopic and histopathologic findings Radiology. 2002 Sep; 224(3):783-7. . View in PubMed

Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression J Nucl Med. 2002 Aug; 43(8):1072-83. . View in PubMed

Evaluation of 2'-deoxy-2'-flouro-5-methyl-1-beta-D-arabinofuranosyluracil as a potential gene imaging agent for HSV-tk expression in vivo Mol Imaging. 2002 Apr-Jun; 1(2):74-81. . View in PubMed

Administration guidelines for radioimmunotherapy of non-Hodgkin's lymphoma with (90)Y-labeled anti-CD20 monoclonal antibody J Nucl Med. 2002 Feb; 43(2):267-72. . View in PubMed

Nonparasitic cysts of the liver: laparoscopic treatment and long-term results Ann Ital Chir. 2002 Jan-Feb; 73(1):85-8; discussion 89. . View in PubMed

Preclinical evaluation of the penciclovir analog 9-(4-[(18)F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET J Nucl Med. 2001 Nov; 42(11):1682-90. . View in PubMed

Gastric and colonic bypass grafts: FDG positron emission tomographic patterns Clin Nucl Med. 2001 Nov; 26(11):955-6. . View in PubMed

A cost analysis of positron emission tomography AJR Am J Roentgenol. 2001 Jul; 177(1):31-40. . View in PubMed

A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents Bioorg Med Chem Lett. 2000 Dec 18; 10(24):2741-3. . View in PubMed

Blocking catabolism with eniluracil enhances PET studies of 5-[18F]fluorouracil pharmacokinetics J Nucl Med. 2000 Oct; 41(10):1714-24. . View in PubMed

Pharmacokinetics of the thymidine analog 2'-fluoro-5-[(14)C]-methyl-1-beta-D-arabinofuranosyluracil ([(14)C]FMAU) in rat prostate tumor cells Nucl Med Biol. 2000 May; 27(4):361-8. . View in PubMed

New indications give PET a lift after struggle over regulatory and reimbursement issues Diagn Imaging (San Franc). 2000 Jan; 22(1):40-7. . View in PubMed

Imaging of locally recurrent and metastatic thyroid cancer with positron emission tomography Thyroid. 1999 Aug; 9(8):797-804. . View in PubMed

Evaluation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors Nucl Med Biol. 1999 May; 26(4):371-6. . View in PubMed

Cerebral vasculopathy in sickle cell anemia: diagnostic contribution of positron emission tomography Blood. 1999 Jan 01; 93(1):71-9. . View in PubMed

Regulation of positron emission tomography: a case study AJR Am J Roentgenol. 1998 Nov; 171(5):1187-92. . View in PubMed

Radiotracer-derived biochemical profiles via a mathematical model: implications for therapeutic intervention Nucl Med Biol. 1998 Nov; 25(8):799-801. . View in PubMed

Seminoma and sarcoidosis: a cause for false positive mediastinal uptake in PET? Ann Oncol. 1998 Aug; 9(8):924.. View in PubMed

Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists Bioorg Med Chem. 1998 Apr; 6(4):401-8. . View in PubMed

Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET Nucl Med Biol. 1998 Apr; 25(3):175-80. . View in PubMed

Alpha-alkylation of amino acid derivatives: synthesis and chiral resolution of [11C]beta-aminoisobutyric acid Nucl Med Biol. 1997 Nov; 24(8):771-5. . View in PubMed

Impact of Rantes and MCP-1 chemokines on in vivo basophilic cell recruitment in rat skin injection model and their role in modifying the protein and mRNA levels for histidine decarboxylase Blood. 1997 Jun 01; 89(11):4120-7. . View in PubMed

Second-look laparotomy for stage III epithelial ovarian cancer: rationale and current issues Cancer Treat Rev. 1996 Nov; 21(6):499-511. . View in PubMed

PET and [18F]-FDG in oncology: a clinical update Nucl Med Biol. 1996 Aug; 23(6):717-35. . View in PubMed

9-[(3-[18F]-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG): a potential imaging agent of viral infection and gene therapy using PET Nucl Med Biol. 1996 Aug; 23(6):787-92. . View in PubMed

System A amino acid transport in cultured human tumor cells: implications for tumor imaging with PET Nucl Med Biol. 1996 Aug; 23(6):779-86. . View in PubMed

Synthesis of [11C-methyl]-alpha-aminoisobutyric acid (AIB) Nucl Med Biol. 1996 Apr; 23(3):263-6. . View in PubMed

Synthesis of 2'-fluoro-5-[11C]-methyl-1-beta-D-arabinofuranosyluracil ([11C]-FMAU): a potential nucleoside analog for in vivo study of cellular proliferation with PET Nucl Med Biol. 1995 Aug; 22(6):783-9. . View in PubMed

Selective alkylation of pyrimidyl dianions III: no-carrier-added synthesis of [11C-methyl]-thymidine Nucl Med Biol. 1995 Aug; 22(6):791-4. . View in PubMed

Introduction to imaging brain tumor metabolism with positron emission tomography (PET) Cancer Invest. 1995; 13(2):244-59. . View in PubMed

High performance liquid chromatography of carbon-11 labeled thymidine and its major catabolites for clinical PET studies Nucl Med Biol. 1994 Nov; 21(8):1045-51. . View in PubMed

Multimodality correlative study of canine brain tumorsProton magnetic resonance spectroscopy, positron emission tomography, and histology. Invest Radiol. 1994 Jun; 29(6):597-605. . View in PubMed

Positron emission tomography: a financial and operational analysis AJR Am J Roentgenol. 1994 Jun; 162(6):1279-86. . View in PubMed

Positron emission tomography in clinical oncology West J Med. 1994 May; 160(5):453-4. . View in PubMed

Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen Neurosurgery. 1993 Mar; 32(3):485-9; discussion 489-90. . View in PubMed

Effects of vasopressin on blood-brain transfer of methionine in dogs J Neurochem. 1992 Oct; 59(4):1421-9. . View in PubMed

Inhibition of interleukin-1 (alpha and beta), interleukin-2 secretion and surface expression of interleukin-2 receptor (IL-2R) by a novel cytokine interleukin-1 receptor antagonist (IL-1ra) Scand J Immunol. 1992 Jul; 36(1):27-33. . View in PubMed

Tumor and organ biochemical profiles determined in vivo following uptake of a combination of radiolabeled substrates: potential applications for PET Am J Physiol Imaging. 1992 Jan-Mar; 7(1):2-11. . View in PubMed

Tumor imaging with carbon-11 labeled alpha-aminoisobutyric acid (AIB) in patients with malignant melanoma Am J Physiol Imaging. 1991 Oct-Dec; 6(4):172-5. . View in PubMed

The applications of PET in clinical oncology J Nucl Med. 1991 Apr; 32(4):623-48; discussion 649-50. . View in PubMed

Advances in medical imaging for cancer diagnosis and treatment Cancer. 1991 Feb 15; 67(4 Suppl):1121-8. . View in PubMed

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Altered peripheral amino acid uptake in obstructive jaundice J Surg Res. 1987 Apr; 42(4):383-93. . View in PubMed

Imaging studies of patients with malignant fibrous histiocytoma using C-11-alpha-aminoisobutyric acid (AIB) Clin Nucl Med. 1987 Jan; 12(1):22-6. . View in PubMed

Tumor localization of the metabolically trapped radiolabeled substrates 2-deoxy-D-glucose and aminocyclopentanecarboxylic acid in human melanoma heterotransplants Am J Clin Oncol. 1986 Dec; 9(6):537-40. . View in PubMed

Tumor imaging with carbon-11 labeled alpha-aminoisobutyric acid (AIB) in a patient with advanced malignant melanoma Eur J Nucl Med. 1986; 12(7):353-6. . View in PubMed

Evaluation of [1-11C]-alpha-aminoisobutyric acid for tumor detection and amino acid transport measurement: spontaneous canine tumor studies Eur J Nucl Med. 1985; 10(1-2):48-55. . View in PubMed

Tumor localization of alpha-aminoisobutyric acid (AIB) in human melanoma heterotransplants Eur J Nucl Med. 1985; 10(1-2):45-7. . View in PubMed

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Selective alkylation of pyrimidyldianions: synthesis and purification of 11C labeled thymidine for tumor visualization using positron emission tomography Int J Appl Radiat Isot. 1984 Aug; 35(8):705-8. . View in PubMed

Synthesis and quality assurance of [11C]alpha-aminoisobutyric acid (AIB), a potential radiotracer for imaging and amino acid transport studies in normal and malignant tissues Int J Nucl Med Biol. 1984; 11(3-4):209-14. . View in PubMed

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Synthesis and purification of the anti-viral agent 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine (FIAC) labeled with iodine-125 Int J Nucl Med Biol. 1984; 11(3-4):215-8. . View in PubMed

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Dr. Conti is a tenured Professor at the University of Southern California with academic appointments in the Departments of Radiology, Biomedical Engineering, and Pharmaceutical Sciences. He received his undergraduate degree from Johns Hopkins University and medical degree from Cornell University. His Ph.D. in Biophysics was completed at Memorial Sloan-Kettering Cancer Center. He is board certified in Nuclear Medicine (ABNM) and Diagnostic Radiology (ABR). Dr. Conti has been the Director of the USC PET Imaging Science Center since its inception in 1991. His research activities have focused on the development of novel PET and hybrid imaging agents for diagnostic and theranostic applications in cancer and other diseases. Dr. Conti has published over 300 peer-reviewed papers in the field of molecular imaging. He is the 2016 recipient of the Paul C Aebersold Award from the Society of Nuclear Medicine and Molecular Imaging for his achievements in the basic science of nuclear medicine, and was the 2018 Peter Valk Award recipient for his pioneering work in clinical Positron Emission Tomography. In 2019 he received a Lifetime Achievement Award from the American College of Nuclear Medicine and in January of 2020, the President’s Award for his service to the College. In June 2020, Dr. Conti received the Benedict Cassen Prize from the Education and Research Foundation for his pioneering work in the development of novel radiopharmaceuticals and clinical PET applications for cancer imaging, and his volunteerism and service to the molecular imaging community. The Prize honors the memory of Benedict Cassen, the inventor of the rectilinear radioisotope scanner—the first instrument capable of making an image of radiotracer distribution in body organs of living patients, and was seminal to the development of clinical nuclear medicine.
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