Keck School Faculty

Peter Stephen Conti, MD, PhD
Peter Stephen Conti, MD, PhD
Professor of Radiology;Director, Molecular Imaging Center;PET Imaging Center Director
Radiology
CSC 103 Health Sciences Campus Los Angeles
Dr. Conti completed his MD at Cornell University Medical College and then went on to Cornell University Graduate School of Medicine to do his Ph.D. in Biophysics. After an Internship in Surgery at St. Lukes Hospital, NY he went on to do his residency in Radiology, and then a fellowship in Nuclear Medicine at John Hopkins Hospital, MD. He joined the staff at USC as a professor of Pharmacy and then Radiology and Biomedical Engineering. Dr. Conti as board certification from the the American Board of Radiology and American Board of Nuclear Medicine.

64Cu-Labeled multifunctional dendrimers for targeted tumor PET imaging Nanoscale. 2018 Mar 29; 10(13):6113-6124. . View in PubMed

Effect of Androgen on Normal Biodistribution of [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in Athymic Non-tumor-bearing Male Mice Anticancer Res. 2017 02; 37(2):475-479. . View in PubMed

A Nanoscale Tool for Photoacoustic-Based Measurements of Clotting Time and Therapeutic Drug Monitoring of Heparin Nano Lett. 2016 Sep 28. . View in PubMed

A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice Int J Cancer. 2016 Feb 15; 138(4):1013-23. . View in PubMed

In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes Methods Mol Biol. 2016; 1444:73-84. . View in PubMed

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan Cell Metab. 2015 Jul 07; 22(1):86-99. . View in PubMed

One-Year Postapproval Clinical Experience with Radium-223 Dichloride in Patients with Metastatic Castrate-Resistant Prostate Cancer Cancer Biother Radiopharm. 2015 Jun; 30(5):195-9. . View in PubMed

Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation Bioconjug Chem. 2015 Mar 18; 26(3):435-42. . View in PubMed

Development of PET probes for cancer imaging Curr Top Med Chem. 2015; 15(8):795-819. . View in PubMed

In vivo NIRF imaging-guided delivery of a novel NGR-VEGI fusion protein for targeting tumor vasculature Amino Acids. 2014 Dec; 46(12):2721-32. . View in PubMed

MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage Mol Pharm. 2014 Nov 03; 11(11):3938-46. . View in PubMed

Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft Mol Pharm. 2014 Nov 03; 11(11):3974-9. . View in PubMed

Integrin a2ß1 targeted GdVO4:Eu ultrathin nanosheet for multimodal PET/MR imaging Biomaterials. 2014 Oct; 35(30):8649-58. . View in PubMed

Axl-targeted cancer imaging with humanized antibody h173 Mol Imaging Biol. 2014 Aug; 16(4):511-8. . View in PubMed

Characterization and evaluation of (64)Cu-labeled A20FMDV2 conjugates for imaging the integrin avß 6 Mol Imaging Biol. 2014 Aug; 16(4):567-77. . View in PubMed

Multimeric disintegrin protein polymer fusions that target tumor vasculature Biomacromolecules. 2014 Jul 14; 15(7):2347-58. . View in PubMed

Efficient synthesis of fluorescent-PET probes based on [¹8F]BODIPY dye Chem Commun (Camb). 2014 Jul 14; 50(55):7371-3. . View in PubMed

Facile Preparation of a Thiol-Reactive (18)F-Labeling Agent and Synthesis of (18)F-DEG-VS-NT for PET Imaging of a Neurotensin Receptor-Positive Tumor J Nucl Med. 2014 Jul; 55(7):1178-84. . View in PubMed

Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy55-labeled dimeric NGR peptide. Amino Acids. 2014 Jun; 46(6):1547-56. . View in PubMed

Development of multi-functional chelators based on sarcophagine cages Molecules. 2014 Apr 03; 19(4):4246-55. . View in PubMed

Patlak image estimation from dual time-point list-mode PET data IEEE Trans Med Imaging. 2014 Apr; 33(4):913-24. . View in PubMed

A hybrid protein-polymer nanoworm potentiates apoptosis better than a monoclonal antibody ACS Nano. 2014 Mar 25; 8(3):2064-76. . View in PubMed

(64)Cu labeled sarcophagine exendin-4 for microPET imaging of glucagon like peptide-1 receptor expression Theranostics. 2014; 4(8):770-7. . View in PubMed

Evaluation of ¹8F-labeled BODIPY dye as potential PET agents for myocardial perfusion imaging Nucl Med Biol. 2014 Jan; 41(1):120-6. . View in PubMed

Functional imaging of human epidermal growth factor receptor 2-positive metastatic breast cancer using (64)Cu-DOTA-trastuzumab PET J Nucl Med. 2014 Jan; 55(1):23-9. . View in PubMed

Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis Clin Cancer Res. 2013 Dec 15; 19(24):6802-11. . View in PubMed

EphB4-targeted imaging with antibody h131, h131-F(ab')2 and h131-Fab Mol Pharm. 2013 Dec 02; 10(12):4527-33. . View in PubMed

Cytoreductive chemotherapy improves the biodistribution of antibodies directed against tumor necrosis in murine solid tumor models Mol Cancer Ther. 2013 Dec; 12(12):2827-36. . View in PubMed

Baseline 18F-FDG PET/CT parameters as imaging biomarkers of overall survival in castrate-resistant metastatic prostate cancer J Nucl Med. 2013 Aug; 54(8):1195-201. . View in PubMed

Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs Biomaterials. 2013 Apr; 34(12):3098-109. . View in PubMed

Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation Mol Imaging. 2013 Mar-Apr; 12(2):121-8. . View in PubMed

Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets J Nucl Med. 2013 Feb; 54(2):244-51. . View in PubMed

Lewis acid-assisted isotopic 18F-19F exchange in BODIPY dyes: facile generation of positron emission tomography/fluorescence dual modality agents for tumor imaging Theranostics. 2013; 3(3):181-9. . View in PubMed

"Kit like" (18)F labeling method for synthesis of RGD peptide-based PET probes Am J Nucl Med Mol Imaging. 2013; 3(1):97-101. . View in PubMed

Efficient construction of PET/fluorescence probe based on sarcophagine cage: an opportunity to integrate diagnosis with treatment Mol Imaging Biol. 2012 Dec; 14(6):718-24. . View in PubMed

Microwave-assisted one-pot radiosynthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-d-arabinofuranosyluracil ([18F]-FMAU) Nucl Med Biol. 2012 Oct; 39(7):1019-25. . View in PubMed

Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells Ann Rheum Dis. 2012 Sep; 71(9):1567-1572. . View in PubMed

[18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in prostate cancer: initial preclinical observations Mol Imaging. 2012 Sep-Oct; 11(5):426-32. . View in PubMed

A Cy55-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice. Amino Acids. 2012 Apr; 42(4):1329-37. . View in PubMed

A potentially common peptide target in secreted heat shock protein-90a for hypoxia-inducible factor-1a-positive tumors Mol Biol Cell. 2012 Feb; 23(4):602-13. . View in PubMed

Evaluation of 64Cu labeled GX1: a phage display peptide probe for PET imaging of tumor vasculature Mol Imaging Biol. 2012 Feb; 14(1):96-105. . View in PubMed

Fasting enhances the response of glioma to chemo- and radiotherapy PLoS One. 2012; 7(9):e44603. . View in PubMed

In vivo near-infrared fluorescence imaging of integrin a2ß1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe J Nucl Med. 2011 Dec; 52(12):1979-86. . View in PubMed

Efficient preparation and biological evaluation of a novel multivalency bifunctional chelator for 64Cu radiopharmaceuticals Chemistry. 2011 Sep 05; 17(37):10222-5. . View in PubMed

Novel a(2)ß(1) integrin-targeted peptide probes for prostate cancer imaging Mol Imaging. 2011 Aug; 10(4):284-94. . View in PubMed

Design, synthesis and validation of integrin a2ß1-targeted probe for microPET imaging of prostate cancer Eur J Nucl Med Mol Imaging. 2011 Jul; 38(7):1313-22. . View in PubMed

18F-5-fluorouracil dynamic positron emission tomography/computed tomography shows decreased tracer activity after bevacizumab in colorectal metastases Nucl Med Commun. 2011 May; 32(5):343-7. . View in PubMed

Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer Eur J Nucl Med Mol Imaging. 2011 Apr; 38(4):642-50. . View in PubMed

Biological stability evaluation of the a2ß1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide Bioconjug Chem. 2011 Feb 16; 22(2):256-63. . View in PubMed

Automated synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-D-arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module Nucl Med Biol. 2011 Feb; 38(2):201-6. . View in PubMed

(64)Cu labeled AmBaSar-RGD2 for micro-PET imaging of integrin avß3 expression Curr Radiopharm. 2011 Jan; 4(1):68-74. . View in PubMed

Improved synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-D-arabinofuranosyluracil ([18F]FMAU) Curr Radiopharm. 2011 Jan; 4(1):24-30. . View in PubMed

Clinical trials network strives for standardization J Nucl Med. 2010 Nov; 51(11):15N. . View in PubMed

Evaluation of copper-64 labeled AmBaSar conjugated cyclic RGD peptide for improved microPET imaging of integrin alphavbeta3 expression Bioconjug Chem. 2010 Aug 18; 21(8):1417-24. . View in PubMed

In vivo effect of propranolol dose and timing on cerebral perfusion after traumatic brain injury J Trauma. 2010 Feb; 68(2):353-6. . View in PubMed

An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[66. 6]icosane-1-ylamino)methyl)benzoic acid, for 64Cu radiopharmaceuticals. Nucl Med Biol. 2010 Jan; 37(1):57-65. . View in PubMed

Controlling familywise error rate for matched subspace detection in dynamic FDG PET IEEE Trans Med Imaging. 2009 Oct; 28(10):1623-31. . View in PubMed

Lesion detection in dynamic FDG-PET using matched subspace detection IEEE Trans Med Imaging. 2009 Feb; 28(2):230-40. . View in PubMed

New directions in the therapeutic strategy to improve survival outcomes in patients with non-Hodgkin's lymphomaSummary. Oncologist. 2009; 14 Suppl 2:52-4. . View in PubMed

New directions in the therapeutic strategy to improve survival outcomes in patients with non-Hodgkin's lymphomaIntroduction. Oncologist. 2009; 14 Suppl 2:1-3. . View in PubMed

Expert opinions on positron emission tomography and computed tomography imaging in lymphoma Oncologist. 2009; 14 Suppl 2:30-40. . View in PubMed

[F-18]-fluorodeoxyglucose PET-CT of the normal prostate gland Ann Nucl Med. 2008 Nov; 22(9):787-93. . View in PubMed

Biglycan overexpression on tooth enamel formation in transgenic mice Anat Rec (Hoboken). 2008 Oct; 291(10):1246-53. . View in PubMed

Molecular imaging: the future of modern medicine J Nucl Med. 2008 Jun; 49(6):16N-20N. . View in PubMed

Choline autoradiography of human prostate cancer xenograft: effect of castration Mol Imaging. 2008 May-Jun; 7(3):147-52. . View in PubMed

B-cell non-Hodgkin lymphoma: PET/CT evaluation after 90Y-ibritumomab tiuxetan radioimmunotherapy--initial experience Radiology. 2008 Mar; 246(3):895-902. . View in PubMed

[F-18]-Fluorodeoxyglucose PET and PET-CT in diagnostic imaging evaluation of locally recurrent and metastatic bladder transitional cell carcinoma Int J Clin Oncol. 2008 Feb; 13(1):42-7. . View in PubMed

F-18 FDG PET and PET/CT evaluation of response to chemotherapy in bone and soft tissue sarcomas Clin Nucl Med. 2008 Jan; 33(1):8-13. . View in PubMed

In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET Nucl Med Biol. 2008 Jan; 35(1):131-41. . View in PubMed

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence Cancer Res. 2007 Aug 01; 67(15):7525-33. . View in PubMed

In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression Eur J Nucl Med Mol Imaging. 2007 Jun; 34(6):822-9. . View in PubMed

Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives Nucl Med Biol. 2007 Apr; 34(3):267-72. . View in PubMed

Detection of occult medullary thyroid cancer recurrence with 2-deoxy-2-[F-18]fluoro-D-glucose-PET and PET/CT Mol Imaging Biol. 2007 Mar-Apr; 9(2):72-7. . View in PubMed

[F-18]fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma J Comput Assist Tomogr. 2007 Mar-Apr; 31(2):223-8. . View in PubMed

Breast MRI and 18F FDG PET/CT in the management of breast cancer Ann Nucl Med. 2007 Jan; 21(1):33-8. . View in PubMed

18F-FDG PET and PET/CT for detection of pulmonary metastases from musculoskeletal sarcomas Nucl Med Commun. 2006 Oct; 27(10):795-802. . View in PubMed

2-Deoxy-2-[18F]fluoro-D-glucose-positron emission tomography and positron emission tomography/computed tomography diagnosis of patients with recurrent papillary thyroid cancer Mol Imaging Biol. 2006 Sep-Oct; 8(5):309-14. . View in PubMed

2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography/computed tomography imaging evaluation of esophageal cancer Mol Imaging Biol. 2006 May-Jun; 8(3):193-200. . View in PubMed

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide Mol Imaging Biol. 2006 Jan-Feb; 8(1):9-15. . View in PubMed

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging Phys Med Biol. 2005 Dec 07; 50(23):5421-41. . View in PubMed

Concurrent PET/CT with an integrated imaging system: intersociety dialogue from the Joint Working Group of the American College of Radiology, the Society of Nuclear Medicine, and the Society of Computed Body Tomography and Magnetic Resonance J Am Coll Radiol. 2005 Jul; 2(7):568-84. . View in PubMed

Concurrent PET/CT with an integrated imaging system: intersociety dialogue from the joint working group of the American College of Radiology, the Society of Nuclear Medicine, and the Society of Computed Body Tomography and Magnetic Resonance J Nucl Med. 2005 Jul; 46(7):1225-39. . View in PubMed

Glucose metabolism of human prostate cancer mouse xenografts Mol Imaging. 2005 Apr-Jun; 4(2):91-7. . View in PubMed

Integrin alpha v beta 3-targeted imaging of lung cancer Neoplasia. 2005 Mar; 7(3):271-9. . View in PubMed

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts Cancer Res. 2004 Nov 01; 64(21):8009-14. . View in PubMed

Musculoskeletal system Semin Nucl Med. 2004 Oct; 34(4):254-61. . View in PubMed

MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides Mol Imaging Biol. 2004 Sep-Oct; 6(5):350-9. . View in PubMed

microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts J Nucl Med. 2004 Aug; 45(8):1390-7. . View in PubMed

MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide Eur J Nucl Med Mol Imaging. 2004 Aug; 31(8):1081-9. . View in PubMed

Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model Mol Imaging. 2004 Apr; 3(2):76-84. . View in PubMed

Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide Mol Imaging. 2004 Apr; 3(2):96-104. . View in PubMed

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis Nucl Med Biol. 2004 Feb; 31(2):179-89. . View in PubMed

MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide Bioconjug Chem. 2004 Jan-Feb; 15(1):41-9. . View in PubMed

FDG PET in suspected recurrent and metastatic prostate cancer Oncol Rep. 2003 Sep-Oct; 10(5):1485-8. . View in PubMed

Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats Cancer Res. 2003 Jul 01; 63(13):3667-74. . View in PubMed

Diagnostic utility of FDG PET in multiple myeloma Skeletal Radiol. 2002 Dec; 31(12):690-4. . View in PubMed

Incidental colonic fluorodeoxyglucose uptake: correlation with colonoscopic and histopathologic findings Radiology. 2002 Sep; 224(3):783-7. . View in PubMed

Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression J Nucl Med. 2002 Aug; 43(8):1072-83. . View in PubMed

Evaluation of 2'-deoxy-2'-flouro-5-methyl-1-beta-D-arabinofuranosyluracil as a potential gene imaging agent for HSV-tk expression in vivo Mol Imaging. 2002 Apr-Jun; 1(2):74-81. . View in PubMed

Administration guidelines for radioimmunotherapy of non-Hodgkin's lymphoma with (90)Y-labeled anti-CD20 monoclonal antibody J Nucl Med. 2002 Feb; 43(2):267-72. . View in PubMed

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