Keck School Faculty

Robert Alan Kloner

Robert Alan Kloner

Professor of Medicine (Clinical Scholar)
IRD 620 Off Campus Los Angeles

Consumer's Research Council of America: Listed in Guide to America's Top Cardiologists, 2007

Good Samaritan Hospital : Physician Leadership Award, 2003

Institute for Scientific Information: Identified as one of the world's most highly cited authors, 2002

American Heart Association: Inaugural Fellow of the Council on Basic Cardiovascular Sciences, 2001

United States Israel Binational Science Foundation: The Henry N. Neufeld Memorial Award, 1996

NIH: Cardiovascular Study Section A, 1995-1998

American Heart Association : Continuing Service Award, 1991

American Society for Clinical Investigation: Elected Member, 1990

82nd Annual Scientific Assembly of the Southern Medical Association: Scientific Exhibit Achievement Award, 1988

American College of Physicians: Research Prize, 1988

American Heart Association: Recipient of the Established Investigatorship Award, 1981-1986

American Society of Clinical Pathologists: Sheard-Sanford Award for Meritorius Original Student Research in Pathology During Medical School, 1976

Merck: Award for Outstanding Achievement in the Study of Medicine, 1975

Alpha Omega Alpha: Member, 1973

Beyond Reperfusion: Acute Ventricular Unloading and Cardioprotection During Myocardial Infarction J Cardiovasc Transl Res. 2019 04; 12(2):95-106. . View in PubMed

A Thank You From the Editor-in-Chief J Cardiovasc Pharmacol Ther. 2019 01; 24(1):90-91. . View in PubMed

A New Perspective on the Nitrate-Phosphodiesterase Type 5 Inhibitor Interaction J Cardiovasc Pharmacol Ther. 2018 09; 23(5):375-386. . View in PubMed

Acute and Subacute Triggers of Cardiovascular Events Am J Cardiol. 2018 12 15; 122(12):2157-2165. . View in PubMed

Cardioprotection: Where to from here? Cardiovasc Drugs Ther. 2017 Feb; 31(1):53-61.. View in PubMed

Angina and Its Management J Cardiovasc Pharmacol Ther. 2017 05; 22(3):199-209. . View in PubMed

Approaches to Improving Cardiac Structure and Function During and After an Acute Myocardial Infarction: Acute and Chronic Phases J Cardiovasc Pharmacol Ther. 2016 07; 21(4):363-7. . View in PubMed

Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart Life Sci. 2015 Nov 15; 141:170-8. . View in PubMed

Bendavia, a mitochondria-targeting peptide, improves postinfarction cardiac function, prevents adverse left ventricular remodeling, and restores mitochondria-related gene expression in rats J Cardiovasc Pharmacol. 2014 Dec; 64(6):543-53. . View in PubMed

Is hypothermia or the salvage kinase pathway involved? Cardiovasc Drugs Ther. 2014 Aug; 28(4):295-301.. View in PubMed

A systematic review of the association between erectile dysfunction and cardiovascular disease Eur Urol. 2014 May; 65(5):968-78. . View in PubMed

All men with vasculogenic erectile dysfunction require a cardiovascular workup Am J Med. 2014 Mar; 127(3):174-82. . View in PubMed

Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know Am J Cardiol. 2014 Jan 01; 113(1):187-90. . View in PubMed

Can myocardial infarct size be reduced by mechanically unloading the left ventricle? Circulation. 2013 Jul 23; 128(4):318-21.. View in PubMed

A brief review of useful tips for publishing your scientific manuscript J Cardiovasc Pharmacol Ther. 2013 May; 18(3):197-8. . View in PubMed

Absence of actions of commonly used Chinese herbal medicines and electroacupuncture on myocardial infarct size J Cardiovasc Pharmacol Ther. 2012 Dec; 17(4):403-11. . View in PubMed

An apoptosis signal-regulating kinase 1 inhibitor reduces cardiomyocyte apoptosis and infarct size in a rat ischemia-reperfusion model J Cardiovasc Pharmacol. 2012 Sep; 60(3):276-82. . View in PubMed

An update on cardioprotection: a review of the latest adjunctive therapies to limit myocardial infarction size in clinical trials J Am Coll Cardiol. 2012 Mar 13; 59(11):969-78. . View in PubMed

Cardiac uses of phosphodiesterase-5 inhibitors J Am Coll Cardiol. 2012 Jan 03; 59(1):9-15. . View in PubMed

Bone marrow-derived cell transplantation therapy for myocardial infarction: lessons learned and future questions Am J Transplant. 2011 Nov; 11(11):2297-301. . View in PubMed

Cardioprotection of insulin-like growth factor-1 during reperfusion therapy: what is the underlying mechanism or mechanisms? Circ Cardiovasc Interv. 2011 Aug; 4(4):311-3.. View in PubMed

Cardiology patient page: cardiovascular implications of erectile dysfunction Circulation. 2011 May 31; 123(21):e609-11. . View in PubMed

Blood supply of the graft after cellular cardiomyoplasty Regen Med. 2010 Sep; 5(5):777-86. . View in PubMed

Cardioprotection with adenosine-regulating agent, GP531: effects on no-reflow, infarct size, and blood flow following ischemia/ reperfusion in the rabbit J Cardiovasc Pharmacol Ther. 2010 Mar; 15(1):60-7. . View in PubMed

Cardioprotective effects of angiotensin II type 1 receptor blockade with olmesartan on reperfusion injury in a rat myocardial ischemia-reperfusion model Cardiovasc Ther. 2010; 28(1):30-7. . View in PubMed

ATL 313, A Selective A(2A) Adenosine Receptor Agonist, Reduces Myocardial Infarct Size in a Rat Ischemia/Reperfusion Model Open Cardiovasc Med J. 2009 Nov 25; 3:166-72. . View in PubMed

A salute to our founding editor-in-chief Bramah NSingh, MD, DPhil, DSc, FRCP. J Cardiovasc Pharmacol Ther. 2009 Sep; 14(3):154-6. . View in PubMed

Blood pressure control with amlodipine add-on therapy in patients with hypertension and diabetes: results of the Amlodipine Diabetic Hypertension Efficacy Response Evaluation Trial Ann Pharmacother. 2008 Nov; 42(11):1552-62. . View in PubMed

Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms J Am Coll Cardiol. 2008 Aug 26; 52(9):719-26. . View in PubMed

Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse J Endocrinol. 2007 Jul; 194(1):63-76. . View in PubMed

ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases Circulation. 2007 Mar 27; 115(12):1656-95. . View in PubMed

ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases J Am Coll Cardiol. 2007 Mar 27; 49(12):1373-412. . View in PubMed

ACCF/AHA/CDC Conference report on emerging infectious diseases and biological terrorism threatsTask Force II: indirect and secondary cardiovascular effects of biological terrorism agents and diseases. J Am Coll Cardiol. 2007 Mar 27; 49(12):1389-97. . View in PubMed

ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threatsTask Force II: indirect and secondary cardiovascular effects of biological terrorism agents and diseases. Circulation. 2007 Mar 27; 115(12):1672-80. . View in PubMed

Can we trigger an acute coronary syndrome? Heart. 2006 Aug; 92(8):1009-10.. View in PubMed

Attempts to recruit stem cells for repair of acute myocardial infarction: a dose of reality JAMA. 2006 Mar 01; 295(9):1058-60. . View in PubMed

Cardiac cells implanted within the outer aortic wall of rats generate measurable contractile force Regen Med. 2006 Jan; 1(1):119-24. . View in PubMed

A case of erectile dysfunction and risk factors for coronary artery disease Int J Impot Res. 2005 Dec; 17 Suppl 1:S7-S11. . View in PubMed

Administration of erythropoietin fails to improve long-term healing or cardiac function after myocardial infarction in the rat J Cardiovasc Pharmacol. 2005 Aug; 46(2):211-5. . View in PubMed

Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects Circulation. 2005 Jul 12; 112(2):214-23. . View in PubMed

A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II) J Am Coll Cardiol. 2005 Jun 07; 45(11):1775-80. . View in PubMed

Acetaminophen and myocardial stunning after transient ischemia in rabbit hearts J Cardiovasc Pharmacol Ther. 2005 Jun; 10(2):121-9. . View in PubMed

Benefit of an exercise program before myocardial infarction J Am Coll Cardiol. 2005 Mar 15; 45(6):939-40. . View in PubMed

Cardiac protection during acute myocardial infarction: where do we stand in 2004? J Am Coll Cardiol. 2004 Jul 21; 44(2):276-86.. View in PubMed

Acetaminophen and experimental acute myocardial infarction Cardiovasc Drugs Ther. 2004 Mar; 18(2):121-5. . View in PubMed

Assessment of cardiovascular risk in patients with erectile dysfunction: focus on the diabetic patient Endocrine. 2004 Mar-Apr; 23(2-3):125-9. . View in PubMed

Age-related changes of cardiac gene expression following myocardial ischemia/reperfusion Arch Biochem Biophys. 2003 Dec 15; 420(2):268-78. . View in PubMed

Brief episode of ischemia activates protective genetic program in rat heart: a gene chip study Cardiovasc Res. 2003 Aug 01; 59(2):450-9. . View in PubMed

Cardiomyocyte transplantation into the failing heart-new therapeutic approach for heart failure? Heart Fail Rev. 2003 Jul; 8(3):201-11.. View in PubMed

A 4-year update on the safety of sildenafil citrate (Viagra) Urology. 2002 Sep; 60(2 Suppl 2):67-90. . View in PubMed

Can moderate alcohol intake limit the size of myocardial infarction? J Cardiovasc Pharmacol. 2001 Jun; 37(6):662-7.. View in PubMed

Adenosine A1 agonist at reperfusion trial (AART): results of a three-center, blinded, randomized, controlled experimental infarct study Cardiovasc Drugs Ther. 2000 Dec; 14(6):607-14. . View in PubMed

Biphasic survival response to amlodipine after myocardial infarction in rats: Association with cardiac vascular remodeling Cardiovasc Pathol. 2000 Mar-Apr; 9(2):85-93. . View in PubMed

A new model of ventricular plication: a suturing technique to decrease left ventricular dimensions, improve contractility, and attenuate ventricular remodeling after myocardial infarction in the rat heart J Cardiovasc Pharmacol Ther. 2000 Jan; 5(1):41-9. . View in PubMed

Brief myocardial ischemia attenuates platelet thrombosis in remote, damaged, and stenotic carotid arteries Circulation. 1999 Aug 24; 100(8):843-8. . View in PubMed

A small animal model of non-ischemic cardiomyopathy and its evaluation by transthoracic echocardiography Cardiovasc Res. 1998 Jul; 39(1):216-23. . View in PubMed

Brief antecedent ischemia attenuates platelet-mediated thrombosis in damaged and stenotic canine coronary arteries: role of adenosine Circulation. 1998 Feb 24; 97(7):692-702. . View in PubMed

[Cardiomyocyte transplantation--a cell replacement for repair of myocardial infarction? ]. Z Kardiol. 1998 Jan; 87(1):1-7.. View in PubMed

Atherosclerotic cardiovascular mortality during the 1992 riots in Los Angeles Am J Cardiol. 1997 Apr 15; 79(8):1155-8. . View in PubMed

Adenovirus-mediated gene transfer into infarcted myocardium: feasibility, timing, and location of expression J Mol Cell Cardiol. 1996 Oct; 28(10):2057-67. . View in PubMed

Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication-defective adenovirus Circulation. 1996 Sep 15; 94(6):1394-401. . View in PubMed

Cardioprotection with ischemic preconditioning and MLA: role of adenosine-regulating enzymes? Am J Physiol. 1996 Sep; 271(3 Pt 2):H1004-14.. View in PubMed

beta-Estradiol, but not alpha-estradiol, reduced myocardial necrosis in rabbits after ischemia and reperfusion Am Heart J. 1996 Aug; 132(2 Pt 1):258-62. . View in PubMed

Benefits of late coronary artery reperfusion on infarct expansion progressively diminish over time: relation to viable islets of myocytes within the scar Am Heart J. 1996 Mar; 131(3):451-7. . View in PubMed

An experimental model examining the role of magnesium in the therapy of acute myocardial infarction Am J Cardiol. 1995 Jun 15; 75(17):1292-3. . View in PubMed

Basic view on the pathobiology of myocardial ischemia during coronary angioplasty: implications for cardiac protection J Interv Cardiol. 1995 Jun; 8(3):291-9. . View in PubMed

Acute cocaine administration induces ventricular regional wall motion and ultrastructural abnormalities in an anesthetized rabbit model Am Heart J. 1994 Dec; 128(6 Pt 1):1117-29. . View in PubMed

Alpha-adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catecholamines mimics ischemic preconditioning Circulation. 1994 Aug; 90(2):1023-8. . View in PubMed

Adenosine deaminase inhibition is not cardioprotective in the rat Am Heart J. 1993 Dec; 126(6):1293-8. . View in PubMed

Ablation and coagulation of myocardial tissue by means of a pulsed holmium:YAG laser Am Heart J. 1993 Dec; 126(6):1474-7. . View in PubMed

An adenosine A1 receptor agonist, R(-)-N-(2-phenylisopropyl)-adenosine (PIA), but not adenosine itself, acts as a therapeutic preconditioning-mimetic agent in rabbits Cardiovasc Res. 1993 Dec; 27(12):2140-5. . View in PubMed

Acute myocardial infarction and diabetes mellitus Cardiovasc Res. 1993 Nov; 27(11):1913-5. . View in PubMed

Can a few good cells now mend a broken heart? J Clin Invest. 1993 Sep; 92(3):1115-6.. View in PubMed

Cardioprotection with angiotensin-converting enzyme inhibitors: redefined for the 1990s Clin Cardiol. 1993 Feb; 16(2):95-103. . View in PubMed

"Cardioprotection" by ACE-inhibitors in acute myocardial ischemia and infarction? Basic Res Cardiol. 1993; 88 Suppl 1:139-54.. View in PubMed

Calcium antagonists and the stunned myocardium: a role during ischaemia? Cardiovasc Res. 1992 Jan; 26(1):82-4.. View in PubMed

Absence of hemodynamic deterioration in the presence of amlodipine following experimental myocardial infarction J Cardiovasc Pharmacol. 1992; 20(5):837-45. . View in PubMed

Calcium antagonists and stunned myocardium: importance for clinicians? Cardiovasc Drugs Ther. 1991 Oct; 5(5):947-51.. View in PubMed

Angiotensin converting enzyme inhibitors improve contractile function of stunned myocardium by different mechanisms of action Am Heart J. 1991 May; 121(5):1319-30. . View in PubMed

Calcium antagonists and the stunned myocardium J Cardiovasc Pharmacol. 1991; 18 Suppl 10:S93-101. . View in PubMed

Beneficial effects of captopril in acute coxsackievirus B3 murine myocarditis Circulation. 1990 Mar; 81(3):1039-46. . View in PubMed

Adverse effects of cocaine on cardiovascular dynamics, myocardial blood flow, and coronary artery diameter in an experimental model Am Heart J. 1989 Nov; 118(5 Pt 1):927-33. . View in PubMed

Analysis of healing after myocardial infarction using polarized light microscopy Am J Pathol. 1989 Apr; 134(4):879-93. . View in PubMed

Altered myocardial statesThe stunned and hibernating myocardium. Am J Med. 1989 Jan 16; 86(1A):14-22. . View in PubMed

Circ Res. 1989 Jan; 64(1):86-96. . View in PubMed

Amelioration of ischemia during angioplasty of the left anterior descending coronary artery with an autoperfusion catheter Am J Cardiol. 1988 Sep 15; 62(9):513-7. . View in PubMed

Atrial natriuretic peptide in acute coxsackievirus murine myocarditis Am J Cardiol. 1988 Jun 01; 61(15):1361-2. . View in PubMed

Calcium channel blockade during ischemia-reperfusion sequences J Mol Cell Cardiol. 1988 May; 20(5):457-9. . View in PubMed

Acute effects of hydralazine and enalapril on contractile function of postischemic "stunned" myocardium Am J Cardiol. 1987 Oct 01; 60(10):934-6. . View in PubMed

5-Fluorouracil cardiotoxicity: left ventricular dysfunction and effect of coronary vasodilators Am J Med Sci. 1987 Oct; 294(4):238-43. . View in PubMed

Analysis of reported randomized trials of streptokinase therapy for acute myocardial infarction in the 1980s Am J Cardiol. 1987 Mar 01; 59(6):501-4. . View in PubMed

Acute myocardial infarction: diagnostic and prognostic applications of two-dimensional echocardiography Circulation. 1987 Mar; 75(3):521-4. . View in PubMed

Capillary anastomoses between the left anterior descending and circumflex circulations in the canine heart: possible importance during coronary artery occlusion Microvasc Res. 1986 Jan; 31(1):54-65. . View in PubMed

Alterations in the distribution of high-energy phosphates during ischemia in a canine model of reperfusion-induced ventricular fibrillation Am Heart J. 1985 Sep; 110(3):590-4. . View in PubMed

Absence of a cumulative deterioration of regional function during three repeated 5 or 15 minute coronary occlusions Circulation. 1984 Feb; 69(2):400-8. . View in PubMed

A flow- and time-dependent index of ischemic injury after experimental coronary occlusion and reperfusion Proc Natl Acad Sci U S A. 1983 Sep; 80(18):5784-8. . View in PubMed

[Reduction of myocardial ischemia with labetalol in experimental myocardial infarct] Wien Med Wochenschr Suppl. 1981; 69:7-9. . View in PubMed

Autoradiographic method for measuring the ischemic myocardium at risk: effects of verapamil on infarct size aftr experimental coronary artery occlusion Proc Natl Acad Sci U S A. 1980 Oct; 77(10):6119-23. . View in PubMed

Analysis of the geometry of myocardial infarct size reduction with hyaluronidase Proc Soc Exp Biol Med. 1980 Oct; 165(1):141-6. . View in PubMed

Assessment of the efficacy of interventions to limit ischemic injury by direct measurement of intramural carbon dioxide tension after coronary artery occlusion in the dog J Clin Invest. 1979 Jan; 63(1):99-107. . View in PubMed

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