Rong Lu, PhD

Professor of Stem Cell Biology & Regenerative Medicine, Biomedical Engineering and Gerontology

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Overview

Rong Lu Lab Website

Research Funding

  • A spatial view of hematopoietic regeneration dynamics in the bone marrow
    NIH · R01DK143671 · Sep 15, 2024 – Jul 31, 2029 · Role: Principal Investigator
  • Using spatial, single-cell genomic recording to investigate age-associated clonal hematopoiesis
    NIH · R01AG080982 · Apr 1, 2023 – Jan 31, 2028 · Role: Principal Investigator
  • Investigating the heterogeneity and coordination of hematopoietic stem cells
    NIH · R35HL150826 · Aug 1, 2020 – Jul 31, 2027 · Role: Principal Investigator
  • Tracing the developmental origin of hematopoietic stem cell heterogeneity
    NIH · R01HL138225 · Aug 28, 2017 – May 31, 2021 · Role: Principal Investigator
  • Investigating the heterogeneous aging of individual hematopoietic stem cell clones
    NIH · R01HL135292 · Aug 1, 2017 – Jul 31, 2022 · Role: Principal Investigator
  • Lineage bias and clonal expansion of hematopoietic stem cell differentiation
    NIH · R00HL113104 · Mar 10, 2014 – Feb 28, 2018 · Role: Principal Investigator
  • Lineage bias and clonal expansion of hematopoietic stem cell differentiation
    NIH · K99HL113104 · Jun 8, 2012 – Mar 31, 2014 · Role: Principal Investigator

Publications

  • Protein phosphatase 2A regulates senescence and immunogenicity in medulloblastoma models. J Clin Invest. 2026 Jul 01; 136(13).. View in PubMed
  • Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Human Glioblastoma Growth by Regulating Mitochondrial Function. bioRxiv. 2026 Jan 09.. View in PubMed
  • Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness. Circ Res. 2025 Jun 06; 136(12):1579-1594.. View in PubMed
  • Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review. J Immunother Cancer. 2025 Jan 16; 13(1).. View in PubMed
  • Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. Cell Mol Immunol. 2024 12; 21(12):1459-1473.. View in PubMed
  • A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm. Mol Oncol. 2024 10; 18(10):2333-2337.. View in PubMed
  • Label-free metabolic optical biomarkers track stem cell fate transition in real time. Sci Adv. 2024 05 10; 10(19):eadi6770.. View in PubMed
  • Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. J Biol Chem. 2024 05; 300(5):107257.. View in PubMed
  • Quantitative association between gene expression and blood cell production of individual hematopoietic stem cells in mice. Sci Adv. 2024 01 26; 10(4):eadk2132.. View in PubMed
  • Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. bioRxiv. 2023 Oct 10.. View in PubMed