Ryan McGinn

Ryan McGinn was born in southeastern British Columbia, Canada. He first began as a professional jazz musician, playing saxophone and flute. He then transitioned to study physics and then neural engineering at the University of Toronto, before completing his medical degree and completing a neurology residency at McMaster University followed by Epilepsy and Clinical Neurophysiology fellowships at Stanford University.Dr. McGinn has a deep interest in clinical epilepsy, particularly with regards to advanced treatments including epilepsy surgery and neuromodulation, including electrical stimulation of the thalamus and cortex. He has published on diverse topics including clinical epilepsy, signal processing in human tissue recordings after epilepsy surgery, stimulation for treatment of epilepsy and recording from the thalamus to understand better how to stimulate the brain to reduce seizure frequency. He has an interest in the interface between medicine, biology, and the quantitative sciences including physics and engineering. In particular, understanding better the states and connectivity associated with seizure, and interventions aimed at improving epilepsy from a state-based and network-based perspective.

• Directional hand movement can be classified from insular cortex SEEG signals using recurrent neural networks and high-gamma band features. Sci Rep. 2025 Aug 16; 15(1):29993.. View in PubMed
• Beta-band power modulation in the human amygdala during a Direct Reach arm reaching task. Neurosci Res. 2025 Jul; 216:104906.. View in PubMed
• Ictal Involvement of the Pulvinar and the Anterior Nucleus of the Thalamus in Patients With Refractory Epilepsy. Neurology. 2024 Dec 10; 103(11):e210039.. View in PubMed
• Association of Intraoperative Hypotension With Delayed Graft Function Following Kidney Transplant: A Single Centre Retrospective Cohort Study. Clin Transplant. 2024 Oct; 38(10):e70000.. View in PubMed
• Intraoperative hemodialysis with supra- and infradiaphragmatic catheters for liver transplantation. Can J Anaesth. 2024 Aug; 71(8):1165-1171.. View in PubMed
• The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nat Med. 2024 May; 30(5):1292-1299.. View in PubMed
• Touch-screen automatisms in the digital age. Epilepsy Behav. 2024 Feb; 151:109588.. View in PubMed
• Attributable Perioperative Cost of Frailty after Major, Elective Noncardiac Surgery: A Population-based Cohort Study. Anesthesiology. 2023 08 01; 139(2):143-152.. View in PubMed
• Multisite thalamic recordings to characterize seizure propagation in the human brain. Brain. 2023 07 03; 146(7):2792-2802.. View in PubMed
• Transcranial direct current stimulation for focal status epilepticus or lateralized periodic discharges in four patients in a critical care setting. Epilepsia. 2023 04; 64(4):875-887.. View in PubMed
• Precision medicine in epilepsy. Prog Mol Biol Transl Sci. 2022; 190(1):147-188.. View in PubMed
• Hospital-, anaesthetist-, and patient-level variation in peripheral nerve block utilisation for hip fracture surgery: a population-based cross-sectional study. Br J Anaesth. 2022 Jan; 128(1):198-206.. View in PubMed
• Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. Crit Care Med. 2021 02 01; 49(2):311-323.. View in PubMed
• Frame-based versus frameless stereotactic brain biopsies: A systematic review and meta-analysis. Surg Neurol Int. 2021; 12:52.. View in PubMed
• Physiological factors characterizing heat-vulnerable older adults: A narrative review. Environ Int. 2020 11; 144:105909.. View in PubMed
• Logging in: a comparative analysis of electronic health records versus anesthesia resident-driven logbooks. Can J Anaesth. 2020 Oct; 67(10):1381-1388.. View in PubMed
• From the Lab to Patients: a Systematic Review and Meta-Analysis of Mesenchymal Stem Cell Therapy for Stroke. Transl Stroke Res. 2020 06; 11(3):345-364.. View in PubMed
• Demographic differences in Canadian medical students’ motivation and confidence to promote physical activity. Fam Pract. 2020 02 19; 37(1):56-62.. View in PubMed
• Canadian medical students’ perceived motivation, confidence and frequency recommending physical activity. Prev Med Rep. 2019 Sep; 15:100898.. View in PubMed
• Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature. PLoS One. 2019; 14(5):e0215221.. View in PubMed
• Screening criteria for increased susceptibility to heat stress during work or leisure in hot environments in healthy individuals aged 31-70 years. Temperature (Austin). 2018; 5(1):86-99.. View in PubMed
• Increasing age is a major risk factor for susceptibility to heat stress during physical activity. Appl Physiol Nutr Metab. 2017 Nov; 42(11):1232-1235.. View in PubMed
• Exploring the mechanisms underpinning sweating: the development of a specialized ventilated capsule for use with intradermal microdialysis. Physiol Rep. 2016 Mar; 4(6).. View in PubMed
• Body temperature regulation in diabetes. Temperature (Austin). 2016 Jan-Mar; 3(1):119-45.. View in PubMed
• Hypoglycemia-induced alterations in hippocampal intrinsic rhythms: Decreased inhibition, increased excitation, seizures and spreading depression. Neurobiol Dis. 2015 Oct; 82:213-225.. View in PubMed
• In vitro recordings of human neocortical oscillations. Cereb Cortex. 2015 Mar; 25(3):578-97.. View in PubMed
• Impairments in local heat loss in type 1 diabetes during exercise in the heat. Med Sci Sports Exerc. 2014 Dec; 46(12):2224-33.. View in PubMed
• Phase-amplitude coupling and interlaminar synchrony are correlated in human neocortex. J Neurosci. 2014 Nov 26; 34(48):15923-30.. View in PubMed
• The origin of segmentation motor activity in the intestine. Nat Commun. 2014; 5:3326.. View in PubMed

• Dunton, Genevieve
• Berger, Theodore