Ryan McGinn

Assistant Professor Of Clinical Neurology

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Ryan McGinn was born in southeastern British Columbia, Canada. He first began as a professional jazz musician, playing saxophone and flute. He then transitioned to study physics and then neural engineering at the University of Toronto, before completing his medical degree and completing a neurology residency at McMaster University followed by Epilepsy and Clinical Neurophysiology fellowships at Stanford University.

Dr. McGinn has a deep interest in clinical epilepsy, particularly with regards to advanced treatments including epilepsy surgery and neuromodulation, including electrical stimulation of the thalamus and cortex. He has published on diverse topics including clinical epilepsy, signal processing in human tissue recordings after epilepsy surgery, stimulation for treatment of epilepsy and recording from the thalamus to understand better how to stimulate the brain to reduce seizure frequency. He has an interest in the interface between medicine, biology, and the quantitative sciences including physics and engineering. In particular, understanding better the states and connectivity associated with seizure, and interventions aimed at improving epilepsy from a state-based and network-based perspective.


  • Touch-screen automatisms in the digital age Epilepsy Behav. 2024 Feb; 151:109588. . View in PubMed
  • Transcranial direct current stimulation for focal status epilepticus or lateralized periodic discharges in four patients in a critical care setting Epilepsia. 2023 04; 64(4):875-887. . View in PubMed
  • Multisite thalamic recordings to characterize seizure propagation in the human brain Brain. 2023 07 03; 146(7):2792-2802. . View in PubMed
  • Precision medicine in epilepsy Prog Mol Biol Transl Sci. 2022; 190(1):147-188. . View in PubMed
  • Frame-based versus frameless stereotactic brain biopsies: A systematic review and meta-analysis Surg Neurol Int. 2021; 12:52. . View in PubMed
  • From the Lab to Patients: a Systematic Review and Meta-Analysis of Mesenchymal Stem Cell Therapy for Stroke Transl Stroke Res. 2020 06; 11(3):345-364. . View in PubMed
  • Increasing age is a major risk factor for susceptibility to heat stress during physical activity Appl Physiol Nutr Metab. 2017 Nov; 42(11):1232-1235. . View in PubMed
  • Exploring the mechanisms underpinning sweating: the development of a specialized ventilated capsule for use with intradermal microdialysis Physiol Rep. 2016 Mar; 4(6). . View in PubMed
  • Body temperature regulation in diabetes Temperature (Austin). 2016 Jan-Mar; 3(1):119-45. . View in PubMed
  • Hypoglycemia-induced alterations in hippocampal intrinsic rhythms: Decreased inhibition, increased excitation, seizures and spreading depression Neurobiol Dis. 2015 Oct; 82:213-225. . View in PubMed
  • In vitro recordings of human neocortical oscillations Cereb Cortex. 2015 Mar; 25(3):578-97. . View in PubMed
  • Impairments in local heat loss in type 1 diabetes during exercise in the heat Med Sci Sports Exerc. 2014 Dec; 46(12):2224-33. . View in PubMed
  • Phase-amplitude coupling and interlaminar synchrony are correlated in human neocortex J Neurosci. 2014 Nov 26; 34(48):15923-30. . View in PubMed
  • The origin of segmentation motor activity in the intestine Nat Commun. 2014; 5:3326. . View in PubMed