Said R Beydoun, MD

Professor of Clinical Neurology

Richard Angus Grant, Sr., Chair in Neurology

Program Director, Clinical Neurophysiology Fellowship

Division Chief, Neuromuscular Disorders

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Overview

Said R. Beydoun, M.D., FAAN, Professor and Division Chief, Neuromuscular Medicine, at the Department of Neurology at Keck Medicine of USC, University of Southern California. He is Program Director of an ACGME-accredited Clinical Neurophysiology Fellowship, which trains three physicians each year. Dr. Beydoun advocates an integrated approach to clinical diagnosis, diagnostic testing, and treatment options for patients with neuromuscular diseases. As a principal investigator, Dr. Beydoun has participated in multiple research clinical trials. His clinical and research areas of expertise in the field of Neuromuscular Medicine include: Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis, Peripheral Neuropathy, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Multifocal Motor Neuropathy (MMN), and TTR Amyloid Neuropathy. He has been published in several scientific journals on topics related to neuromuscular diseases. He is co-Editor-in-Chief of TouchReviews in Neurology. He is an elected fellow of the American Academy of Neurology and a fellow of the American Association of Neuromuscular and Electrodiagnostic Medicine. He is a member of the medical/scientific advisory board of the Myasthenia Gravis Foundation of America. He is medical director of the Certified ALS Treatment Center of Excellence at Keck USC. He holds board certification by the American Board of Psychiatry and Neurology in Neurology, Clinical Neurophysiology, Neuromuscular Medicine, and Pain Medicine.

Publications

  • Paraproteinemic Neuropathies Continuum (Minneap Minn). 2023 10 01; 29(5):1492-1513. . View in PubMed
  • Impact of the updated chronic inflammatory demyelinating polyneuropathy guideline on everyday clinical practice Ther Adv Neurol Disord. 2023; 16:17562864231190549. . View in PubMed
  • Long-term safety, tolerability, and efficacy of efgartigimod (ADAPT+): interim results from a phase 3 open-label extension study in participants with generalized myasthenia gravis Front Neurol. 2023; 14:1284444. . View in PubMed
  • Clinical Meaningfulness of Response to Tanezumab in Patients with Chronic Low Back Pain: Analysis From a 56-Week, Randomized, Placebo- and Tramadol-Controlled, Phase 3 Trial Pain Ther. 2022 Dec; 11(4):1267-1285. . View in PubMed
  • Reducing body myopathy associated with the LIM2 p(His123Arg) FHL1 variant. Clin Neurol Neurosurg. 2021 08; 207:106795. . View in PubMed
  • Individualizing Therapy in CIDP: A Mini-Review Comparing the Pharmacokinetics of Ig With SCIg and IVIg Front Neurol. 2021; 12:638816. . View in PubMed
  • Individualizing Therapy in CIDP: A Mini-Review Comparing the Pharmacokinetics of Ig With SCIg and IVIg Frontiers in Neurology. 2021; 12:1-8. . View in PubMed
  • Polyneuropathy Reveals Origins of Decade-long Gastrointestinal Symptoms in a Patient With Undiagnosed Mitochondrial Neurogastrointestinal Encephalopathy Caused by a Novel Mutation J Clin Neuromuscul Dis. 2020 Dec; 22(2):97-102. . View in PubMed
  • Minimal manifestation status and prednisone withdrawal in the MGTX trial Neurology. 2020 08 11; 95(6):e755-e766. . View in PubMed
  • A Retrospective Review to Evaluate the Demographics and Management Profile of Patients with Amyotrophic Lateral Sclerosis Patients Attending A Multidisciplinary Clinic US Neurology. 2020; 2(16):110-115. . View in PubMed
  • Porphyria-induced Recurrent Quadriplegia Misdiagnosed as Guillain Barre Syndrome US Neurology. 2020; 1(16):66-69. . View in PubMed
  • Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study Front Neurol. 2020; 11:556104. . View in PubMed
  • Wound Botulism in a Drug User-A Case Report and a Review of Botulism US Neurology. 2020; 2(16):116-119. . View in PubMed
  • Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial Lancet Neurol. 2019 03; 18(3):259-268. . View in PubMed
  • Spinal Muscular Atrophy, Two Case Reports of Compound Heterozygosity US Neurology. 2019; 2(15):97-99. . View in PubMed
  • Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis Neurology. 2019 06 04; 92(23):e2661-e2673. . View in PubMed
  • The Challenges of Distinguishing POEMS from Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)Importance of Early Recognition and Diagnosis of POEMS. US Neurology. 2018; 2(14). . View in PubMed
  • Late Onset Hereditary Transthyretin Amyloidosis Polyneuropathy in Two Patients with Acquired Demyelinating Features US Neurology. 2018; 2(14):98-101. . View in PubMed
  • Edaravone in Amyotrophic Lateral Sclerosis-Lessons from the Clinical Development Program and the Importance of a Strategic Clinical Design US Neurology. 2018; 1(14):47-53. . View in PubMed
  • Utility of Neurological Imaging in Sensory Variant of Chronic Inflammatory Demyelinating Polyneuropathy: A Case Report J Clin Neuromuscul Dis. 2017 Mar; 18(3):157-159. . View in PubMed
  • Delayed Appearance of Conduction Block in Multifocal Motor Neuropathy US Neurology. 2017; 2(13):99-102. . View in PubMed
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy 101—Pitfalls and Pearls of Diagnosis and Treatment US Neurology. 2017; 13(1):26-34. . View in PubMed
  • When to write a neurology case report J Med Case Rep. 2016 Apr 06; 10:92. . View in PubMed
  • Disulfiram neuropathy: two case reports J Med Case Rep. 2016 Mar 31; 10:72. . View in PubMed
  • Paraproteinemic neuropathy: a practical review BMC Neurol. 2016 Jan 28; 16:13. . View in PubMed
  • Different Presentations of Myelopathy—A Case Series US Neurology. 2016; 12(1):22-26. . View in PubMed
  • Randomized Trial of Thymectomy in Myasthenia Gravis N Engl J Med. 2016 08 11; 375(6):511-22. . View in PubMed
  • Chronic Inflammatory Demyelinating Polyneuropathy Manifesting as Neuropathy With Liability to Pressure Palsies: A Case Report J Clin Neuromuscul Dis. 2015 Dec; 17(2):78-83. . View in PubMed
  • Misdiagnosis of inclusion body myositis: two case reports and a retrospective chart review J Med Case Rep. 2015 Aug 13; 9:169. . View in PubMed
  • Chiari malformation type I with cervicothoracic syringomyelia masquerading as bibrachial amyotrophy: a case report J Med Case Rep. 2015 Jan 27; 9:11. . View in PubMed
  • Differentiating Multifocal Motor Neuropathy from Entrapment Neuropathy – A Diagnostic Challenge US Neurology. 2015; 12(1):17-21. . View in PubMed
  • Myasthenia gravis associated with invasive malignant thymoma: two case reports and a review of the literature J Med Case Rep. 2014 Oct 13; 8:340. . View in PubMed
  • A controlled trial of intravenous immunoglobulin in multifocal motor neuropathy J Peripher Nerv Syst. 2013 Dec; 18(4):321-30. . View in PubMed
  • Kennedy disease misdiagnosed as polymyositis: a case report BMC Res Notes. 2013 Sep 28; 6:389. . View in PubMed
  • Hereditary neuropathy with liability to pressure palsy: two cases of difficult diagnosis J Clin Neuromuscul Dis. 2013 Sep; 15(1):28-33. . View in PubMed
  • Cervicothoracic spinal cord and pontomedullary injury secondary to high-voltage electrocution: a case report J Med Case Rep. 2012 Sep 13; 6:296. . View in PubMed
  • Clinical and imaging findings in three patients with advanced inflammatory demyelinating polyradiculoneuropathy associated with nerve root hypertrophy J Clin Neuromuscul Dis. 2012 Mar; 13(3):105-12. . View in PubMed
  • Bilateral phrenic neuropathies in a diabetic patient responsive to intravenous immunoglobulin: a case report Clin Neurol Neurosurg. 2011 Nov; 113(9):788-91. . View in PubMed
  • Delayed cervicobulbar neuronopathy and myokymia after head and neck radiotherapy for nasopharyngeal carcinoma: a case report J Clin Neuromuscul Dis. 2011 Mar; 12(3):147-52. . View in PubMed
  • Emotional stress as a trigger of myasthenic crisis and concomitant takotsubo cardiomyopathy: a case report J Med Case Rep. 2010 Dec 03; 4:393. . View in PubMed
  • Chronic immune-mediated demyelinating polyneuropathy in the setting of cetuximab treatment Clin Neurol Neurosurg. 2010 Dec; 112(10):900-2. . View in PubMed
  • Amyotrophic lateral sclerosis-motor neuron disease, monoclonal gammopathy, hyperparathyroidism, and B12 deficiency: case report and review of the literature J Med Case Rep. 2010 Sep 01; 4:298. . View in PubMed
  • Teaching Video NeuroImages: tongue myokymia following head and neck radiotherapy for nasopharyngeal carcinoma Neurology. 2009 Apr 07; 72(14):e65. . View in PubMed
  • Hereditary neuropathy with liability to pressure palsies: description of seven patients without known family history Acta Neurol Scand. 2008 Apr; 117(4):266-72. . View in PubMed
  • Long-term safety and tolerability of oxcarbazepine in painful diabetic neuropathy Acta Neurol Scand. 2007 Apr; 115(4):284-8. . View in PubMed
  • Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study Eur J Pain. 2005 Oct; 9(5):543-54. . View in PubMed
  • Secondary amyloidosis as a life-ending event in multifocal motor neuropathy Muscle Nerve. 2001 Oct; 24(10):1396-402. . View in PubMed
  • Bilateral phrenic neuropathy as a presenting feature of multifocal motor neuropathy with conduction block Muscle Nerve. 2000 Apr; 23(4):556-9. . View in PubMed
  • Generalized myokymia as a unique association with gluten-sensitive enteropathy Eur Neurol. 2000; 44(4):254-5. . View in PubMed
  • Severe preeclampsia remote from term: labor induction or elective cesarean delivery? Am J Obstet Gynecol. 1998 Nov; 179(5):1210-3.. View in PubMed
  • Multifocal motor neuropathy with conduction block misdiagnosed as multiple entrapment neuropathies Muscle Nerve. 1998 Jun; 21(6):813-5. . View in PubMed
  • Neuralgic amyotrophy misdiagnosed as diaphragmatic rupture Muscle Nerve. 1996 Sep; 19(9):1181-2. . View in PubMed
  • Delayed presentation of a partial palmar ulnar motor neuropathy in a chemist; secondary to a rare “occupational hazard” Muscle Nerve. 1995 Feb; 18(2):255-6. . View in PubMed
  • Facial myokymia secondary to neurocysticercosis Muscle Nerve. 1994 Sep; 17(9):1060-1. . View in PubMed
  • Delayed diagnosis of Lambert-Eaton myasthenic syndrome in a patient presenting with recurrent refractory respiratory failure Muscle Nerve. 1994 Jun; 17(6):689-90. . View in PubMed
  • Unilateral trigeminal motor neuropathy as a presenting feature of neurofibromatosis type 2 (NF2) Muscle Nerve 1993 Oct; 16(10):1136-7. . View in PubMed
  • Obstetrical lumbosacral plexus injury Muscle Nerve. 1993 Jul; 16(7):801. . View in PubMed
  • Calf muscle hypertrophy, complex repetitive discharges and spinal stenosis Muscle Nerve. 1993 Mar; 16(3):322-3. . View in PubMed
  • Misdiagnosis of cytomegalovirus polyradiculopathy, coexisting with HIV neuropathy Muscle Nerve. 1991 Jun; 14(6):575-6. . View in PubMed
  • Long-term plasmapheresis therapy is effective and safe in children with chronic relapsing dysimmune polyneuropathy Rev Neurol (Paris). 1990; 146(2):123-7. . View in PubMed
  • Evaluation of surgical staples in cesarean section Am J Obstet Gynecol. 1989 Sep; 161(3):540-5; discussion 545-7. . View in PubMed
  • Ifosfamide encephalopathy J Toxicol Clin Toxicol. 1989; 27(4-5):293-8. . View in PubMed
  • Analogs of thyrotropin-releasing hormone: hypotheses relating receptor binding to net excitation of spinal lower motor neurons Biochem Biophys Res Commun. 1986 Aug 14; 138(3):1184-90. . View in PubMed