Shannon M Mumenthaler
USC: Medical Faculty Women's Association Award, 2013
National Cancer Institute: Junior Investigator Award, 2013
Third Annual National Cancer Institute Physical Sciences in Oncology Center: Best Poster Award, 2012
University of California, Los Angeles: Hortenese Fishbaugh Memorial Scholarship, 2006-2007
University of California, Los Angeles: Life Sciences Core Curriculum Teaching Assistant Honorarium Award, 2005-2006
University of California, Davis: Graduated with Honors, 2003
University of California, Davis: Undergraduate Student of the Year Award, Division of Biological Sciences, 2003
University of California, Davis: Howard Hughes Medical Institute Summer Honors Advanced Research Program (SHARP) Fellowship, 2002
University of California, Davis: Alumni Scholarship, 2000
Webber Foundation: Academic Scholarship, 1999-2003
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data Cell Rep Methods. 2023 Mar 27; 3(3):100417. . View in PubMed
Organs-on-chips: a decade of innovation Trends Biotechnol. 2023 03; 41(3):278-280. . View in PubMed
Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions Oncogene. 2023 02; 42(9):627-637. . View in PubMed
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer Nat Commun. 2023 04 17; 14(1):2140. . View in PubMed
Neurotransmitter signaling: a new frontier in colorectal cancer biology and treatment Oncogene. 2022 10; 41(43):4769-4778. . View in PubMed
Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer Br J Cancer. 2022 01; 126(1):72-78. . View in PubMed
Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics Metab Eng. 2022 01; 69:175-187. . View in PubMed
Reprogramming CBX8-PRC1 function with a positive allosteric modulatorCell Chem Biol. 2022 04 21; 29(4):555-571. e11. . View in PubMed
Roadmap on plasticity and epigenetics in cancer Phys Biol. 2022 04 18; 19(3). . View in PubMed
Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread iScience. 2021 May 21; 24(5):102509. . View in PubMed
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer Mol Oncol. 2021 10; 15(10):2801-2817. . View in PubMed
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration Clin Transl Sci. 2021 09; 14(5):1659-1680. . View in PubMed
Germ line polymorphisms of genes involved in pluripotency transcription factors predict efficacy of cetuximab in metastatic colorectal cancer Eur J Cancer. 2021 06; 150:133-142. . View in PubMed
RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC Mol Cancer Ther. 2021 06; 20(6):1153-1160. . View in PubMed
Clocking cancer: the circadian clock as a target in cancer therapy Oncogene. 2021 05; 40(18):3187-3200. . View in PubMed
Imaging-Based Machine Learning Analysis of Patient-Derived Tumor Organoid Drug Response Front Oncol. 2021; 11:771173. . View in PubMed
Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach Sci Rep. 2021 01 18; 11(1):1710. . View in PubMed
High-throughput microscopy reveals the impact of multifactorial environmental perturbations on colorectal cancer cell growth Gigascience. 2021 04 19; 10(4). . View in PubMed
Multiplexed imaging and effluent analysis to monitor cancer cell intravasation using a colorectal cancer-on-chip STAR Protoc. 2021 12 17; 2(4):100984. . View in PubMed
Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance Cancers (Basel). 2020 May 28; 12(6). . View in PubMed
Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer J Immunother Cancer. 2020 11; 8(2). . View in PubMed
A Perspective on Expanding Our Understanding of Cancer Treatments by Integrating Approaches from the Biological and Physical Sciences SLAS Discov. 2020 08; 25(7):672-683. . View in PubMed
Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response SLAS Discov. 2020 08; 25(7):744-754. . View in PubMed
Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3 Eur J Cancer. 2019 04; 111:138-147. . View in PubMed
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice Nat Commun. 2019 12 12; 10(1):5681. . View in PubMed
AMPK variant, a candidate of novel predictor for chemotherapy in metastatic colorectal cancer: A meta-analysis using TRIBE, MAVERICC and FIRE3 Int J Cancer. 2019 10 15; 145(8):2082-2090. . View in PubMed
MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids J Am Soc Mass Spectrom. 2018 03; 29(3):516-526. . View in PubMed
PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems PLoS Comput Biol. 2018 02; 14(2):e1005991. . View in PubMed
mTORC2 contributes to the metabolic reprogramming in EGFR tyrosine-kinase inhibitor resistant cells in non-small cell lung cancer Cancer Lett. 2018 10 10; 434:152-159. . View in PubMed
MALDI-MSI of Immunotherapy: Mapping the EGFR-Targeting Antibody Cetuximab in 3D Colon-Cancer Cell Cultures Anal Chem. 2018 12 18; 90(24):14156-14164. . View in PubMed
Image-Based Tracking of Heterogeneous Single-Cell Phenotypes Methods Mol Biol. 2018; 1745:47-63. . View in PubMed
Characterization of the mechanical properties of resected porcine organ tissue using optical fiber photoelastic polarimetry Biomed Opt Express. 2017 Oct 01; 8(10):4663-4670. . View in PubMed
Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques J Vis Exp. 2017 06 30; (124). . View in PubMed
Quantifying differences in cell line population dynamics using CellPD BMC Syst Biol. 2016 Sep 21; 10(1):92. . View in PubMed
Leveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid Tumors PLoS Comput Biol. 2016 08; 12(8):e1005077. . View in PubMed
Dual transcript and protein quantification in a massive single cell array Lab Chip. 2016 10 07; 16(19):3682-8. . View in PubMed
Progress Towards Computational 3-D Multicellular Systems Biology Adv Exp Med Biol. 2016; 936:225-246. . View in PubMed
A high-content image-based method for quantitatively studying context-dependent cell population dynamics Sci Rep. 2016 07 25; 6:29752. . View in PubMed
Significance of duon mutations in cancer genomes Sci Rep. 2016 06 08; 6:27437. . View in PubMed
Single cell dynamic phenotyping Sci Rep. 2016 10 06; 6:34785. . View in PubMed
The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells Cancer Inform. 2015; 14(Suppl 4):19-31. . View in PubMed
Predictive Modeling of Drug Response in Non-Hodgkin's Lymphoma PLoS One. 2015; 10(6):e0129433. . View in PubMed
Phosphorylated ribosomal S6 (p-rpS6) as a post-treatment indicator of HER2 signalling targeted drug resistance Biomarkers. 2015; 20(5):313-22. . View in PubMed
Anti-MET immunoPET for non-small cell lung cancer using novel fully human antibody fragments Mol Cancer Ther. 2014 Nov; 13(11):2607-17. . View in PubMed
The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation Front Oncol. 2013; 3:194. . View in PubMed
Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors Evol Appl. 2013 Jan; 6(1):54-69. . View in PubMed
A physical sciences network characterization of non-tumorigenic and metastatic cells Sci Rep. 2013; 3:1449. . View in PubMed
Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer Mol Pharm. 2011 Dec 05; 8(6):2069-79. . View in PubMed
Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes Mol Cancer Ther. 2009 Oct; 8(10):2882-93. . View in PubMed
17beta-estradiol prevents early-stage atherosclerosis in estrogen receptor-alpha deficient female mice J Cardiovasc Transl Res. 2009 Sep; 2(3):289-99. . View in PubMed
CD4+ NK cells can be productively infected with HIV, leading to downregulation of CD4 expression and changes in function Virology. 2009 Apr 25; 387(1):59-66. . View in PubMed
Disruption of arginase II alters prostate tumor formation in TRAMP mice Prostate. 2008 Oct 01; 68(14):1561-9. . View in PubMed
Expression of arginase II in prostate cancer Int J Oncol. 2008 Feb; 32(2):357-65. . View in PubMed
