Shohreh F. Farzan, PhD

Associate Professor of Population and Public Health Sciences

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Overview

Dr. Shohreh Farzan is an environmental epidemiologist, with a background in molecular biology and toxicology. Dr. Farzan received her BA from Mount Holyoke College (2004) and her PhD in Pharmacology and Toxicology from Dartmouth Medical School under the mentorship of Dr. David Robbins (2009). Dr. Farzan completed her postdoctoral training in environmental epidemiology at the Geisel School of Medicine at Dartmouth, under the mentorship of Dr. Margaret Karagas, prior to joining the Keck School of Medicine at USC in 2016.

Dr. Farzan’s research focuses on the impact of environmental contaminants on maternal-child health, with a special interest in cardiometabolic health. Much of Dr. Farzan’s work focuses on the role of environmental exposures in altering preclinical indicators of cardiovascular and metabolic disease risk, particularly during vulnerable lifestages, such as childhood and pregnancy. Within the Maternal and Developmental Risks of Environmental and Social Stressors (MADRES) study, a NIMHD-funded Center of Excellence on Environmental Health Disparities Research, she focuses on the role of prenatal air pollutants and psychosocial stressors on maternal postpartum cardiometabolic health. Dr. Farzan also leads multiple studies of the impacts of toxic metals and air pollutants on preclinical biomarkers of cardiovascular dysfunction in children and adolescents, both as PI of a NIEHS R01 to investigate the role of air pollutants in the development of atherosclerosis in the transition from childhood to young adulthood and as MPI of the ECHO LA DREAMERs study. She is also MPI of a NIEHS Research to Action R01 that established the Children’s AIRE cohort to investigate environmental contributors to children’s respiratory health in a rural border region of California to inform community-engaged public health actions and the recipient of a NIEHS K99/R00 Pathway to Independence Award.

Awards

  • NIH Loan Repayment Award, 2017
     – 2019
  • University of Southern California: Provost’s Assistant Professor Fellowship, 2016
  • Society of Toxicology, Occupational and Public Health Specialty Section: Paper of the Year, 2016
  • Children’s Environmental Health Network: Article of the Month (Nov 2015), 2015
  • International Society of Environmental Epidemiology: ISEE Annual Meeting Travel Award, 2015
  • Children’s Environmental Health Network: Article of the Month (June 2015), 2015
  • National Cancer Institute Epidemiology and Genomics Research Program: Research Highlights 2014 Selected Manuscript, 2014
  • NIEHS Superfund Research Program: KC Donnelly Externship Award, 2013
  • American Association of Cancer Research: AACR Scholar-in-Training AFLAC Travel Award, 2013
  • NIEHS: Children’s Center Meeting Travel Award, 2012
  • Faculty of 1000 Biology Featured Article, 2010
  • Dartmouth Medical School: Rosalind Borison Memorial Pre-doctoral Fellowship Award, 2008
     – 2009
  • Dartmouth Medical School: Albert J Ryan Foundation Fellowship, 2006
     – 2008
  • AAAS: Program for Excellence in Science, 2006
     – 2008

Education and Training

  • Mount Holyoke College, South Hadley, MA — BA — 2004 — Biological Sciences
  • Dartmouth College, Hanover, NH — PhD — 2010 — Pharmacology & Toxicology
  • Weill Cornell Medical College, New York, NY — Postdoctoral — 2011 — Pediatric Infectious Disease
  • Geisel School of Medicine at Dartmouth, Hanover, NH — Postdoctoral — 2016 — Environmental Epidemiology

Research Funding

  • Wildfire smoke, heat and cardiovascular risk across the life course
    NIH · R01ES036559 · Jun 23, 2025 – Apr 30, 2030 · Role: Principal Investigator
  • Children?s Cardiovascular Health and the Impacts of Heat Stress and Wildfire Smoke
    NIH · R01ES036185 · Jan 23, 2024 – Nov 30, 2029 · Role: Principal Investigator
  • Air Pollutant Exposure and Progression of Subclinical Atherosclerosis during the Crticial Transition from Childhood to Adulthood
    NIEHS · Dec 16, 2020 – Oct 31, 2025 · Role: Principal Investigator
  • Air pollutant exposure and progression of subclinical atherosclerosis during the critical transition from childhood to adulthood
    NIH · R01ES031590 · Dec 16, 2020 – Oct 31, 2025 · Role: Principal Investigator
  • Maternal And Developmental Risks From Environmental And Social Stressors (MADRES) Project 2: Maternal Exposure To Environmental And Psychosocial Stressors And Cardiovascular Risks After Pregnancy
    NIMHD · Jul 18, 2020 – Mar 31, 2025 · Role: Project 2 Principal Investigator
  • Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory health (LA DREAMERs)
    NIH · 1UH3OD023287-01 · Sep 21, 2018 – Aug 31, 2023 · Role: Multiple Principal Investigator
  • The Salton Sea and Children's Health: Assessing Imperial Valley Respiratory Health and the Environment
    NIH · R01ES029598 · Jul 15, 2018 – Apr 30, 2024 · Role: Principal Investigator
  • Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory health (LA DREAMERs)
    NIH · UH3OD023287 · Sep 21, 2016 – Aug 31, 2023 · Role: Co-Principal Investigator
  • Preclinical Indicators & Biomarkers of Cardiovascular Effects of Arsenic Exposure
    NIH · R00ES024144 · Aug 1, 2016 – Jul 31, 2021 · Role: Principal Investigator
  • PRECLINICAL INDICATORS & BIOMARKERS OF CARDIOVASCULAR EFFECTS OF ARSENIC EXPOSURE
    NIH · K99ES024144 · Sep 17, 2014 – Aug 31, 2016 · Role: Principal Investigator

Research Keywords

  • Children's Health
  • Maternal prenatal and postpartum health
  • Cardiometabolic health
  • Air pollution
  • Toxic metals
  • Environmental Exposures
  • Health disparities
  • Respiratory health

Publications

  • Self-Reported Sleep Quality in Late Pregnancy Is Associated With Early-Childhood Growth Trajectories in Children Aged 0-2 Years in Hispanic Populations. Am J Prev Med. 2027 Sep 22; 108546.. View in PubMed
  • Prenatal exposure to wildfire fine particulate matter and fetal growth outcomes in the United States: Findings from the ECHO Cohort. Environ Epidemiol. 2026 Oct; 10(5):e526.. View in PubMed
  • Prenatal fluoride exposure and motor development among infants in Los Angeles, California. Environ Res. 2026 Sep 15; 306(Pt 2):125235.. View in PubMed
  • Understanding the importance of social and environmental stressors in predicting maternal sleep quality during late pregnancy. Environ Res. 2026 Sep 01; 305(Pt 2):125013.. View in PubMed
  • Maternal and early-life arsenic exposure and relative telomere length in children: Findings from the BiRCH cohort. Environ Res. 2026 Sep 01; 305(Pt 2):124924.. View in PubMed
  • Preconception and early-pregnancy exposure to ambient air pollution and trajectories of depressive symptoms during pregnancy. Environ Health. 2026 Jun 02.. View in PubMed
  • Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort. JAMA Netw Open. 2026 06 01; 9(6):e2618883.. View in PubMed
  • Maternal Heat Shock Protein as a Potential Biomarker of Adaptation to Heat Stress during Pregnancy and Its Relation to Preterm Birth. Environ Sci Technol. 2026 May 12; 60(18):13323-13332.. View in PubMed
  • Per- and Polyfluoroalkyl Substances During Pregnancy and Gestational Diabetes: The Environmental Influences on Child Health Outcomes (ECHO) Cohort. Diabetes Care. 2026 May 01; 49(5):852-860.. View in PubMed
  • Addressing Pregnancy Outcomes to Improve Offspring Health. JAMA Netw Open. 2026 May 01; 9(5):e266788.. View in PubMed