Keck School Faculty

Epidermal GIGANTEA adjusts the response to shade at dusk by directly impinging on PHYTOCHROME INTERACTING FACTOR 7 function bioRxiv. 2023 Mar 23. . View in PubMed

Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2214829120. . View in PubMed

Phosphorylation of RNA Polymerase II by CDKC;2 Maintains the Arabidopsis Circadian Clock Period Plant Cell Physiol. 2022 Apr 19; 63(4):450-462. . View in PubMed

The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain the circadian clock J Cell Sci. 2022 10 01; 135(19). . View in PubMed

CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy Proc Natl Acad Sci U S A. 2022 10 04; 119(40):e2203936119. . View in PubMed

Clocking cancer: the circadian clock as a target in cancer therapy Oncogene. 2021 05; 40(18):3187-3200. . View in PubMed

Two bHLH transcription factors, bHLH48 and bHLH60, associate with phytochrome interacting factor 7 to regulate hypocotyl elongation in Arabidopsis Cell Rep. 2021 05 04; 35(5):109054. . View in PubMed

A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms Proc Natl Acad Sci U S A. 2021 01 05; 118(1). . View in PubMed

HNF4A defines tissue-specific circadian rhythms by beaconing BMAL1::CLOCK chromatin binding and shaping the rhythmic chromatin landscape Nat Commun. 2021 11 03; 12(1):6350. . View in PubMed

Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues Int J Mol Sci. 2020 Sep 03; 21(17). . View in PubMed

Changes in ambient temperature are the prevailing cue in determining Brachypodium distachyon diurnal gene regulation New Phytol. 2020 09; 227(6):1709-1724. . View in PubMed

Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis Osteoarthritis Cartilage. 2020 07; 28(7):966-976. . View in PubMed

Isoform-selective regulation of mammalian cryptochromes Nat Chem Biol. 2020 06; 16(6):676-685. . View in PubMed

A mobile ELF4 delivers circadian temperature information from shoots to roots Nat Plants. 2020 04; 6(4):416-426. . View in PubMed

COP1 destabilizes DELLA proteins in Arabidopsis Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13792-13799. . View in PubMed

An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in MammalsCell Chem Biol. 2020 09 17; 27(9):1192-1198. e5. . View in PubMed

Light Perception: A Matter of Time Mol Plant. 2020 03 02; 13(3):363-385. . View in PubMed

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock Cancer Discov. 2019 11; 9(11):1556-1573. . View in PubMed

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth Sci Adv. 2019 01; 5(1):eaau9060. . View in PubMed

Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Ia and d J Med Chem. 2019 02 28; 62(4):1989-1998. . View in PubMed

Functional dissection of the ARGONAUTE7 promoter Plant Direct. 2019 Jan; 3(1):e00102. . View in PubMed

Multi-level Modulation of Light Signaling by GIGANTEA Regulates Both the Output and Pace of the Circadian ClockDev Cell. 2019 06 17; 49(6):840-851. e8. . View in PubMed

CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation Nat Commun. 2019 09 02; 10(1):3916. . View in PubMed

GIGANTEA gates gibberellin signaling through stabilization of the DELLA proteins in Arabidopsis Proc Natl Acad Sci U S A. 2019 10 22; 116(43):21893-21899. . View in PubMed

Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen Sci Rep. 2019 08 27; 9(1):12405. . View in PubMed

Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11528-11536. . View in PubMed

The 6xABRE Synthetic Promoter Enables the Spatiotemporal Analysis of ABA-Mediated Transcriptional Regulation Plant Physiol. 2018 08; 177(4):1650-1665. . View in PubMed

Decoys Untangle Complicated Redundancy and Reveal Targets of Circadian Clock F-Box Proteins Plant Physiol. 2018 07; 177(3):1170-1186. . View in PubMed

ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth in Arabidopsis Proc Natl Acad Sci U S A. 2018 05 08; 115(19):E4503-E4511. . View in PubMed

Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks Proc Natl Acad Sci U S A. 2018 12 26; 115(52):E12305-E12312. . View in PubMed

Guidelines for Genome-Scale Analysis of Biological Rhythms J Biol Rhythms. 2017 Oct; 32(5):380-393. . View in PubMed

Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis Nat Genet. 2017 Oct; 49(10):1546-1552. . View in PubMed

TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis PLoS Genet. 2017 Jun; 13(6):e1006856. . View in PubMed

Plant Stress Tolerance Requires Auxin-Sensitive Aux/IAA Transcriptional Repressors Curr Biol. 2017 Feb 06; 27(3):437-444. . View in PubMed

Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9655-E9664. . View in PubMed

Arabidopsis B-BOX32 interacts with CONSTANS-LIKE3 to regulate flowering Proc Natl Acad Sci U S A. 2017 01 03; 114(1):172-177. . View in PubMed

A Modified Yeast-one Hybrid System for Heteromeric Protein Complex-DNA Interaction Studies J Vis Exp. 2017 07 24; (125). . View in PubMed

Comparative Analysis of Vertebrate Diurnal/Circadian Transcriptomes PLoS One. 2017; 12(1):e0169923. . View in PubMed

Molecular mechanisms at the core of the plant circadian oscillator Nat Struct Mol Biol. 2016 Dec; 23(12):1061-1069. . View in PubMed

The Plant Circadian Clock: From a Simple Timekeeper to a Complex Developmental Manager Cold Spring Harb Perspect Biol. 2016 Dec 01; 8(12). . View in PubMed

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBa Degradation Cell. 2016 Jun 16; 165(7):1644-1657. . View in PubMed

The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation Elife. 2016 Mar 04; 5:e11794. . View in PubMed

Cardiac Abnormalities in Adult Patients With Polymyositis or Dermatomyositis as Assessed by Noninvasive Modalities Arthritis Care Res (Hoboken). 2016 07; 68(7):1012-20. . View in PubMed

Identification of Arabidopsis Transcriptional Regulators by Yeast One-Hybrid Screens Using a Transcription Factor ORFeome Methods Mol Biol. 2016; 1398:107-18. . View in PubMed

Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry Mol Cell Proteomics. 2016 Jan; 15(1):201-17. . View in PubMed

Cultivated tomato clock runs slow Nat Genet. 2016 Jan; 48(1):8-9. . View in PubMed

Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci Dev Cell. 2015 Nov 09; 35(3):311-21. . View in PubMed

Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock ChemMedChem. 2015 Sep; 10(9):1489-97. . View in PubMed

Identification of Open Stomata1-Interacting Proteins Reveals Interactions with Sucrose Non-fermenting1-Related Protein Kinases2 and with Type 2A Protein Phosphatases That Function in Abscisic Acid Responses Plant Physiol. 2015 Sep; 169(1):760-79. . View in PubMed

Genome-wide identification of CCA1 targets uncovers an expanded clock network in Arabidopsis Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):E4802-10. . View in PubMed

Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):9166-73. . View in PubMed

C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock Angew Chem Int Ed Engl. 2015 Jun 08; 54(24):7193-7. . View in PubMed

A parametric classification rule based on the exponentially embedded family IEEE Trans Neural Netw Learn Syst. 2015 Feb; 26(2):367-77. . View in PubMed

An Arabidopsis gene regulatory network for secondary cell wall synthesis Nature. 2015 Jan 29; 517(7536):571-5. . View in PubMed

Control of plant stem cell function by conserved interacting transcriptional regulators Nature. 2015 Jan 15; 517(7534):377-80. . View in PubMed

Identification of small-molecule modulators of the circadian clock Methods Enzymol. 2015; 551:267-82. . View in PubMed

Tissue-specific clocks in Arabidopsis show asymmetric coupling Nature. 2014 Nov 20; 515(7527):419-22. . View in PubMed

HsfB2b-mediated repression of PRR7 directs abiotic stress responses of the circadian clock Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):16172-7. . View in PubMed

Nitrate foraging by Arabidopsis roots is mediated by the transcription factor TCP20 through the systemic signaling pathway Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15267-72. . View in PubMed

FBH1 affects warm temperature responses in the Arabidopsis circadian clock Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):14595-600. . View in PubMed

A genome-scale resource for the functional characterization of Arabidopsis transcription factors Cell Rep. 2014 Jul 24; 8(2):622-32. . View in PubMed

Transcriptional regulation of LUX by CBF1 mediates cold input to the circadian clock in Arabidopsis Curr Biol. 2014 Jul 07; 24(13):1518-24. . View in PubMed

CD84 is a survival receptor for CLL cells Oncogene. 2014 Feb 20; 33(8):1006-16. . View in PubMed

Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):2040-5. . View in PubMed

Daily changes in temperature, not the circadian clock, regulate growth rate in Brachypodium distachyon PLoS One. 2014; 9(6):e100072. . View in PubMed

Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock Dev Biol. 2013 Aug 15; 380(2):259-73. . View in PubMed

Global approaches for telling time: omics and the Arabidopsis circadian clock Semin Cell Dev Biol. 2013 May; 24(5):383-92. . View in PubMed

BRANCHED1 interacts with FLOWERING LOCUS T to repress the floral transition of the axillary meristems in Arabidopsis Plant Cell. 2013 Apr; 25(4):1228-42. . View in PubMed

Circadian surprise--it's not all about transcription Science. 2012 Oct 19; 338(6105):338-40. . View in PubMed

CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):17129-34. . View in PubMed

Identification of small molecule activators of cryptochrome Science. 2012 Aug 31; 337(6098):1094-7. . View in PubMed

Complexity in the wiring and regulation of plant circadian networks Curr Biol. 2012 Aug 21; 22(16):R648-57. . View in PubMed

Linking photoreceptor excitation to changes in plant architecture Genes Dev. 2012 Apr 15; 26(8):785-90. . View in PubMed

Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3167-72. . View in PubMed

[Circadian clocks and photoperiodism] Fukuoka Igaku Zasshi. 2012 Feb; 103(2):29-34. . View in PubMed

Cell-autonomous hepatic circadian clock regulates polyamine synthesis Cell Cycle. 2012 Feb 01; 11(3):422-3. . View in PubMed

ELF3 recruitment to the PRR9 promoter requires other Evening Complex members in the Arabidopsis circadian clock Plant Signal Behav. 2012 Feb; 7(2):170-3. . View in PubMed

Gene transfer in Leptolyngbya spstrain BL0902, a cyanobacterium suitable for production of biomass and bioproducts. PLoS One. 2012; 7(1):e30901. . View in PubMed

Rapid in vivo testing of drug response in multiple myeloma made possible by xenograft to turkey embryos Br J Cancer. 2011 Nov 22; 105(11):1708-18. . View in PubMed

Cell-autonomous circadian clock of hepatocytes drives rhythms in transcription and polyamine synthesis Proc Natl Acad Sci U S A. 2011 Nov 08; 108(45):18560-5. . View in PubMed

A small molecule modulates circadian rhythms through phosphorylation of the period protein Angew Chem Int Ed Engl. 2011 Nov 04; 50(45):10608-11. . View in PubMed

Enhanced Y1H assays for Arabidopsis Nat Methods. 2011 Oct 30; 8(12):1053-5. . View in PubMed

The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth Nature. 2011 Jul 13; 475(7356):398-402. . View in PubMed

GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana Proc Natl Acad Sci U S A. 2011 Jul 12; 108(28):11698-703. . View in PubMed

Automated analysis of hypocotyl growth dynamics during shade avoidance in Arabidopsis Plant J. 2011 Mar; 65(6):991-1000. . View in PubMed

LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock Curr Biol. 2011 Jan 25; 21(2):126-33. . View in PubMed

Global profiling of rice and poplar transcriptomes highlights key conserved circadian-controlled pathways and cis-regulatory modules PLoS One. 2011; 6(6):e16907. . View in PubMed

High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIa as a clock regulatory kinase PLoS Biol. 2010 Dec 14; 8(12):e1000559. . View in PubMed

Clocks not winding down: unravelling circadian networks Nat Rev Mol Cell Biol. 2010 Nov; 11(11):764-76. . View in PubMed

Emergence of noise-induced oscillations in the central circadian pacemaker PLoS Biol. 2010 Oct 12; 8(10):e1000513. . View in PubMed

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis Nat Med. 2010 Oct; 16(10):1152-6. . View in PubMed

Climate change and the integrity of science Science. 2010 May 07; 328(5979):689-90. . View in PubMed

An expanding universe of circadian networks in higher plants Trends Plant Sci. 2010 May; 15(5):259-65. . View in PubMed

F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression Plant Cell. 2010 Mar; 22(3):606-22. . View in PubMed

Suprachiasmatic nucleus: cell autonomy and network properties Annu Rev Physiol. 2010; 72:551-77. . View in PubMed

Circadian control of global gene expression patterns Annu Rev Genet. 2010; 44:419-44. . View in PubMed

A genome-wide RNAi screen for modifiers of the circadian clock in human cells Cell. 2009 Oct 02; 139(1):199-210. . View in PubMed

High-throughput screening and chemical biology: new approaches for understanding circadian clock mechanisms Chem Biol. 2009 Sep 25; 16(9):921-7. . View in PubMed

A model of the cell-autonomous mammalian circadian clock Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11107-12. . View in PubMed

Cytochrome P450 monooxygenases as reporters for circadian-regulated pathways Plant Physiol. 2009 Jun; 150(2):858-78. . View in PubMed

HSP90, a capacitor of behavioral variation J Biol Rhythms. 2009 Jun; 24(3):183-92. . View in PubMed

A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock Science. 2009 Mar 13; 323(5920):1481-5. . View in PubMed

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2097-103. . View in PubMed

Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays Genome Biol. 2009 Feb 11; 10(2):R17. . View in PubMed

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20746-51. . View in PubMed

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation Leukemia. 2008 Dec; 22(12):2151-5158. . View in PubMed

SnapShot: circadian clock proteinsCell. 2008 Oct 17; 135(2):368-368. e1. . View in PubMed

A morning-specific phytohormone gene expression program underlying rhythmic plant growth PLoS Biol. 2008 Sep 16; 6(9):e225. . View in PubMed

[Molecular mechanism by which plant determines flowering timing with circadian clock] Tanpakushitsu Kakusan Koso. 2008 May; 53(6):739-46. . View in PubMed

Photoperiodic flowering occurs under internal and external coincidence Plant Signal Behav. 2008 Apr; 3(4):269-71. . View in PubMed

Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms PLoS Genet. 2008 Feb 29; 4(2):e1000023. . View in PubMed

Network discovery pipeline elucidates conserved time-of-day-specific cis-regulatory modules PLoS Genet. 2008 Feb; 4(2):e14. . View in PubMed

Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development Genome Biol. 2008; 9(8):R130. . View in PubMed

Circadian rhythmsDaily watch on metabolism. Science. 2007 Dec 14; 318(5857):1730-1. . View in PubMed

PRR3 Is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock Plant Cell. 2007 Nov; 19(11):3462-73. . View in PubMed

PRR7 protein levels are regulated by light and the circadian clock in Arabidopsis Plant J. 2007 Nov; 52(3):548-60. . View in PubMed

Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP J Biol Chem. 2007 Oct 26; 282(43):31349-57. . View in PubMed

FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis Science. 2007 Oct 12; 318(5848):261-5. . View in PubMed

Mammalian circadian signaling networks and therapeutic targets Nat Chem Biol. 2007 Oct; 3(10):630-9. . View in PubMed

Plant biology: time for growth Nature. 2007 Jul 19; 448(7151):265-6. . View in PubMed

Genome-wide patterns of single-feature polymorphism in Arabidopsis thaliana Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12057-62. . View in PubMed

In SYNC: the ins and outs of circadian oscillations in calcium Sci STKE. 2007 Jun 12; 2007(390):pe32. . View in PubMed

Intercellular coupling confers robustness against mutations in the SCN circadian clock network Cell. 2007 May 04; 129(3):605-16. . View in PubMed

Impaired clock output by altered connectivity in the circadian network Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5650-5. . View in PubMed

The DIURNAL project: DIURNAL and circadian expression profiling, model-based pattern matching, and promoter analysis Cold Spring Harb Symp Quant Biol. 2007; 72:353-63. . View in PubMed

Exploring spatiotemporal organization of SCN circuits Cold Spring Harb Symp Quant Biol. 2007; 72:527-41. . View in PubMed

Photoperiodic control of flowering: not only by coincidence Trends Plant Sci. 2006 Nov; 11(11):550-8. . View in PubMed

A constitutive shade-avoidance mutant implicates TIR-NBS-LRR proteins in Arabidopsis photomorphogenic development Plant Cell. 2006 Nov; 18(11):2919-28. . View in PubMed

Arabidopsis FHY3 specifically gates phytochrome signaling to the circadian clock Plant Cell. 2006 Oct; 18(10):2506-16. . View in PubMed

Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription J Neurochem. 2006 Jul; 98(1):248-57. . View in PubMed

Feedback repression is required for mammalian circadian clock function Nat Genet. 2006 Mar; 38(3):312-9. . View in PubMed

A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9 Mol Syst Biol. 2006; 2:58. . View in PubMed

Circadian rhythms lit up in Chlamydomonas Genome Biol. 2006; 7(4):215. . View in PubMed

LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10387-92. . View in PubMed

FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis Science. 2005 Jul 08; 309(5732):293-7. . View in PubMed

Positive and negative factors confer phase-specific circadian regulation of transcription in Arabidopsis Plant Cell. 2005 Jul; 17(7):1926-40. . View in PubMed

Rapid array mapping of circadian clock and developmental mutations in Arabidopsis Plant Physiol. 2005 Jun; 138(2):990-7. . View in PubMed

Bioluminescence imaging in living organisms Curr Opin Biotechnol. 2005 Feb; 16(1):73-8. . View in PubMed

Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock Curr Biol. 2005 Jan 11; 15(1):47-54. . View in PubMed

Real-time reporting of circadian-regulated gene expression by luciferase imaging in plants and mammalian cells Methods Enzymol. 2005; 393:269-88. . View in PubMed

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression Curr Biol. 2004 Dec 29; 14(24):2289-95. . View in PubMed

Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes Am J Transplant. 2004 Sep; 4(9):1475-89. . View in PubMed

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock Neuron. 2004 Aug 19; 43(4):527-37. . View in PubMed

Universality and flexibility in gene expression from bacteria to human Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3765-9. . View in PubMed

Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana Nature. 2003 Dec 04; 426(6966):567-70. . View in PubMed

A PERIOD inhibitor buffer introduces a delay mechanism for CLK/CYC-activated transcription FEBS Lett. 2003 Dec 04; 555(2):341-5. . View in PubMed

The F box protein AFR is a positive regulator of phytochrome A-mediated light signaling Curr Biol. 2003 Dec 02; 13(23):2091-6. . View in PubMed

HY5, Circadian Clock-Associated 1, and a cis-element, DET1 dark response element, mediate DET1 regulation of chlorophyll a/b-binding protein 2 expression Plant Physiol. 2003 Dec; 133(4):1565-77. . View in PubMed

A genomic analysis of the shade avoidance response in Arabidopsis Plant Physiol. 2003 Dec; 133(4):1617-29. . View in PubMed

FKF1 is essential for photoperiodic-specific light signalling in Arabidopsis Nature. 2003 Nov 20; 426(6964):302-6. . View in PubMed

Gene arrays are not just for measuring gene expression Trends Plant Sci. 2003 Sep; 8(9):413-6. . View in PubMed

Melanopsin is required for non-image-forming photic responses in blind mice Science. 2003 Jul 25; 301(5632):525-7. . View in PubMed

Circadian clocks in daily and seasonal control of development Science. 2003 Jul 18; 301(5631):326-8. . View in PubMed

Living by the calendar: how plants know when to flower Nat Rev Mol Cell Biol. 2003 Apr; 4(4):265-75. . View in PubMed

DNA arrays: applications and implications for circadian biology J Biol Rhythms. 2003 Apr; 18(2):96-105. . View in PubMed

Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3380-5. . View in PubMed

Circadian transcriptional output in the SCN and liver of the mouse Novartis Found Symp. 2003; 253:171-80; discussion 52-5102-9180-3 passim. . View in PubMed

Circadian light input in plants, flies and mammals Novartis Found Symp. 2003; 253:73-82; discussion 82-8102-9281-4. . View in PubMed

Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis Plant Cell. 2003 Jan; 15(1):223-36. . View in PubMed

Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting Science. 2002 Dec 13; 298(5601):2213-6. . View in PubMed

Molecular basis of seasonal time measurement in Arabidopsis Nature. 2002 Sep 19; 419(6904):308-12. . View in PubMed

tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator Dev Cell. 2002 Jul; 3(1):51-61. . View in PubMed

Circadian rhythms from flies to human Nature. 2002 May 16; 417(6886):329-35. . View in PubMed

Coordinated transcription of key pathways in the mouse by the circadian clock Cell. 2002 May 03; 109(3):307-20. . View in PubMed

Critical role for CCA1 and LHY in maintaining circadian rhythmicity in Arabidopsis Curr Biol. 2002 Apr 30; 12(9):757-61. . View in PubMed

A P element with a novel fusion of reporters identifies regular, a C2H2 zinc-finger gene downstream of the circadian clock Mol Cell Neurosci. 2002 Apr; 19(4):501-14. . View in PubMed

A role for LKP2 in the circadian clock of Arabidopsis Plant Cell. 2001 Dec; 13(12):2659-70. . View in PubMed

Regulation of the cycling of timeless (tim) RNA J Neurobiol. 2001 Jun 05; 47(3):161-75. . View in PubMed

The limits of GMO detection Nat Biotechnol. 2001 May; 19(5):405. . View in PubMed

Analysis of the function of two circadian-regulated CONSTANS-LIKE genes Plant J. 2001 Apr; 26(1):15-22. . View in PubMed

Sequence interpretationFunctional annotation of mouse genome sequences. Science. 2001 Feb 16; 291(5507):1251-5. . View in PubMed

Circadian photoperception Annu Rev Physiol. 2001; 63:677-94. . View in PubMed

Orchestrated transcription of key pathways in Arabidopsis by the circadian clock Science. 2000 Dec 15; 290(5499):2110-3. . View in PubMed

The period E-box is sufficient to drive circadian oscillation of transcription in vivo J Biol Rhythms. 2000 Dec; 15(6):462-71. . View in PubMed

Cryptochromes are required for phytochrome signaling to the circadian clock but not for rhythmicity Plant Cell. 2000 Dec; 12(12):2499-2510. . View in PubMed

Specific sequences outside the E-box are required for proper per expression and behavioral rescue J Biol Rhythms. 2000 Dec; 15(6):472-82. . View in PubMed

Functional interaction of phytochrome B and cryptochrome 2 Nature. 2000 Nov 09; 408(6809):207-11. . View in PubMed

Circadian rhythm genetics: from flies to mice to humans Nat Genet. 2000 Sep; 26(1):23-7. . View in PubMed

Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog Science. 2000 Aug 04; 289(5480):768-71. . View in PubMed

Flower arranging in Arabidopsis Science. 2000 Jun 02; 288(5471):1600-2. . View in PubMed

Fluorescent differential display identifies circadian clock-regulated genes in Arabidopsis thaliana J Biol Rhythms. 2000 Jun; 15(3):208-17. . View in PubMed

Microarrays: determining the balance of cellular transcription Plant Cell. 2000 May; 12(5):613-6. . View in PubMed

ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis Cell. 2000 Apr 28; 101(3):319-29. . View in PubMed

Time flies for Drosophila Cell. 2000 Feb 04; 100(3):297-300. . View in PubMed

Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene Science. 1999 Sep 03; 285(5433):1579-82. . View in PubMed

A patient preference study comparing raltitrexed ('Tomudex') and bolus or infusional 5-fluorouracil regimens in advanced colorectal cancer: influence of side-effects and administration attributes Eur J Cancer Care (Engl). 1999 Sep; 8(3):154-61. . View in PubMed

Cryptochromes--bringing the blues to circadian rhythms Trends Cell Biol. 1999 Aug; 9(8):295-8. . View in PubMed

Light-dependent sequestration of TIMELESS by CRYPTOCHROME Science. 1999 Jul 23; 285(5427):553-6. . View in PubMed

Light-dependent translocation of a phytochrome B-GFP fusion protein to the nucleus in transgenic Arabidopsis J Cell Biol. 1999 May 03; 145(3):437-45. . View in PubMed

The ins and outs of circadian regulated gene expression Curr Opin Plant Biol. 1999 Apr; 2(2):114-20. . View in PubMed

Synchronous real-time reporting of multiple cellular events Methods Cell Biol. 1999; 58:283-91. . View in PubMed

The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila Cell. 1998 Nov 25; 95(5):681-92. . View in PubMed

Phytochromes and cryptochromes in the entrainment of the Arabidopsis circadian clock Science. 1998 Nov 20; 282(5393):1488-90. . View in PubMed

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim Science. 1998 Jun 05; 280(5369):1599-603. . View in PubMed

An Arabidopsis mutant hypersensitive to red and far-red light signals Plant Cell. 1998 Jun; 10(6):889-904. . View in PubMed

Transcription of Arabidopsis and wheat Cab genes in single tobacco transgenic seedlings exhibits independent rhythms in a developmentally regulated fashion Plant J. 1998 Feb; 13(4):563-9. . View in PubMed

The short-period mutant, toc1-1, alters circadian clock regulation of multiple outputs throughout development in Arabidopsis thaliana Development. 1998 Feb; 125(3):485-94. . View in PubMed

Independent photoreceptive circadian clocks throughout Drosophila Science. 1997 Nov 28; 278(5343):1632-5. . View in PubMed

Attenuation of phytochrome A and B signaling pathways by the Arabidopsis circadian clock Plant Cell. 1997 Oct; 9(10):1727-43. . View in PubMed

Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures Curr Biol. 1997 Oct 01; 7(10):758-66. . View in PubMed

Reporter gene expression for monitoring gene transfer Curr Opin Biotechnol. 1997 Oct; 8(5):617-22. . View in PubMed

Multiple circadian-regulated elements contribute to cycling period gene expression in Drosophila EMBO J. 1997 Aug 15; 16(16):5006-18. . View in PubMed

Coordination of Plant Metabolism and Development by the Circadian Clock Plant Cell. 1997 Jul; 9(7):1235-1244. . View in PubMed

Quantitative analysis of Drosophila period gene transcription in living animals J Biol Rhythms. 1997 Jun; 12(3):204-17. . View in PubMed

As time PASses: the first mammalian clock gene Science. 1997 May 16; 276(5315):1093. . View in PubMed

PAS, present, and future: clues to the origins of circadian clocks Science. 1997 May 02; 276(5313):753-4. . View in PubMed

The genetics of phototransduction and circadian rhythms in Arabidopsis Bioessays. 1997 Mar; 19(3):209-14. . View in PubMed

Phototransduction and circadian clock pathways regulating gene transcription in higher plants Adv Genet. 1997; 35:1-34. . View in PubMed

Integration of circadian and phototransduction pathways in the network controlling CAB gene transcription in Arabidopsis Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15491-6. . View in PubMed

Conditional circadian dysfunction of the Arabidopsis early-flowering 3 mutant Science. 1996 Nov 01; 274(5288):790-2. . View in PubMed

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