Keck School Faculty

Steven Siegel, MD, PhD
Steven Siegel, MD, PhD
Franz Alexander Chair in Psychiatry, Professor and Chair, Psychiatry and the Behavioral Sciences
Psychiatry and The Behavioral Sciences
CSC 2250 Alcazar St. Health Sciences Campus Los Angeles

High-beta/low-gamma frequency activity reflects top-down predictive coding during a spatial working memory test Exp Brain Res. 2019 Jul; 237(7):1881-1888. . View in PubMed

Parvalbumin Cell Ablation of NMDA-R1 Leads to Altered Phase, But Not Amplitude, of Gamma-Band Cross-Frequency Coupling Brain Connect. 2019 04; 9(3):263-272. . View in PubMed

Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease Prog Neuropsychopharmacol Biol Psychiatry. 2019 07 13; 93:84-92. . View in PubMed

Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity Exp Brain Res. 2018 03; 236(3):837-846. . View in PubMed

Mismatch negativity in preclinical models of schizophrenia Schizophr Res. 2018 01; 191:35-42. . View in PubMed

Amygdala activity associated with social choice in mice Behav Brain Res. 2017 08 14; 332:84-89. . View in PubMed

Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models Front Behav Neurosci. 2016; 10:136. . View in PubMed

Mouse Model of Chromosome 15q133 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder. J Neurosci. 2015 Dec 09; 35(49):16282-94. . View in PubMed

Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism Behav Neurosci. 2015 Aug; 129(4):389-98. . View in PubMed

EEG biomarkers of target engagement, therapeutic effect, and disease process Ann N Y Acad Sci. 2015 May; 1344:12-26. . View in PubMed

Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability Biol Psychiatry. 2015 Mar 15; 77(6):556-68. . View in PubMed

Mice with subtle reduction of NMDA NR1 receptor subunit expression have a selective decrease in mismatch negativity: Implications for schizophrenia prodromal population Neurobiol Dis. 2015 Jan; 73:289-95. . View in PubMed

The Role of Nicotine in Schizophrenia Int Rev Neurobiol. 2015; 124:23-78. . View in PubMed

[Ketamine alters socially-evoked activity in the amygdala] Nihon Yakurigaku Zasshi. 2014 Dec; 144(6):272-6. . View in PubMed

Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits Neuropsychopharmacology. 2014 Jun; 39(7):1603-13. . View in PubMed

Electroencephalographic and early communicative abnormalities in Brattleboro rats Physiol Rep. 2013 Oct; 1(5):e00100. . View in PubMed

Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression Psychopharmacology (Berl). 2013 Jun; 227(4):639-49. . View in PubMed

Knockout of NMDA receptors in parvalbumin interneurons recreates autism-like phenotypes Autism Res. 2013 Apr; 6(2):69-77. . View in PubMed

The electrophysiological signature of motivational salience in mice and implications for schizophrenia Neuropsychopharmacology. 2012 Dec; 37(13):2846-54. . View in PubMed

Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice Neurobiol Dis. 2012 Sep; 47(3):338-46. . View in PubMed

MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder Neurobiol Dis. 2012 Apr; 46(1):88-92. . View in PubMed

Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density Behav Neurosci. 2012 Apr; 126(2):332-43. . View in PubMed

Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials PLoS One. 2012; 7(7):e39775. . View in PubMed

Mouse behavioral endophenotypes for schizophrenia Brain Res Bull. 2010 Sep 30; 83(3-4):147-61. . View in PubMed

Predator odor modulates auditory event-related potentials in mice Neuroreport. 2009 Sep 23; 20(14):1260-4. . View in PubMed

Profile of auditory information-processing deficits in schizophrenia Psychiatry Res. 2009 Jan 30; 165(1-2):27-37. . View in PubMed

Attitudes of patients and family members towards implantable psychiatric medication Schizophr Res. 2008 Oct; 105(1-3):279-86. . View in PubMed

Male and female mice differ for baseline and nicotine-induced event related potentials Behav Neurosci. 2008 Oct; 122(5):982-90. . View in PubMed

Deviance-elicited changes in event-related potentials are attenuated by ketamine in mice J Cogn Neurosci. 2008 Aug; 20(8):1403-14. . View in PubMed

Effects of nicotine vary across two auditory evoked potentials in the mouse Biol Psychiatry. 2007 Jan 01; 61(1):23-30. . View in PubMed

Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives Schizophr Res. 2006 Dec; 88(1-3):151-60. . View in PubMed

The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components Neurochem Res. 2004 Jun; 29(6):1179-88. . View in PubMed

Symptom and demographic profiles in first-episode schizophrenia Schizophr Res. 2004 Apr 01; 67(2-3):185-94. . View in PubMed

Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential Neuropsychopharmacology. 2004 Apr; 29(4):739-46. . View in PubMed

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