Suraiya Rasheed, PhD

Professor of Pathology

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Overview

Proteomics of cancer and neuronal cells Differential protein expression profiles of HIV infection. Biological and molecular characterization of human retroviruses involved in cancer and AIDS (HTLV-I, HTLV-II, HIV-I, HIV-2, etc.). Molecular mechanisms of AIDS-related lymphoma and other hematologic disorders. Role of endogenous viral and cellular genes in cell differentiation and ransformation. Molecular and genetic analysis of viral and cellular oncogenes expressed in Leukemia and other tumors including those of unknown etiology or induced by chemical carcinogens. Molecular Mechanisms of Oncogene Transduction by Retroviruses. Pathogenesis of HIV-disease and the Acquired Immunodeficiency Syndrome (AIDS). Evaluation of Vaccines and Antiviral Drug Effects in AIDS Clinical Trials. Molecular Characterization of HIV Genotypes, Identification of Mutations Involved in Conferring Drug-resistance Sequence Analysis.

Research Funding

  • INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARD
    NIH · T32AI007383 · Aug 1, 1990 – Jul 31, 1995 · Role: Principal Investigator
  • LEUKEMIA &SARCOMA GENES IN CELLULAR TRANSFORMATION
    NIH · R01CA027246 · Dec 1, 1979 – Jun 30, 1986 · Role: Principal Investigator

Publications

  • Possible Biomarkers for the Early Detection of HIV-associated Heart Diseases: A Proteomics and Bioinformatics Prediction. Comput Struct Biotechnol J. 2015; 13:145-52.. View in PubMed
  • Identification of human microRNA-like sequences embedded within the protein-encoding genes of the human immunodeficiency virus. PLoS One. 2013; 8(3):e58586.. View in PubMed
  • Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways. J Transl Med. 2009 Aug 27; 7:75.. View in PubMed
  • HIV replication enhances production of free fatty acids, low density lipoproteins and many key proteins involved in lipid metabolism: a proteomics study. PLoS One. 2008 Aug 20; 3(8):e3003.. View in PubMed
  • Inferring protein-protein interaction networks from protein complex data. Int J Bioinform Res Appl. 2007; 3(4):480-92.. View in PubMed
  • Molecular and phylogenetic analyses of a new amphotropic murine leukemia virus (MuLV-1313). Virol J. 2006 Dec 05; 3:101.. View in PubMed
  • Is Melanoma a stem cell tumor? Identification of neurogenic proteins in trans-differentiated cells. J Transl Med. 2005 Mar 22; 3(1):14.. View in PubMed
  • Genetic analysis of the rat leukemia virus: influence of viral sequences in transduction of the c-ras proto-oncogene and expression of its transforming activity. J Virol. 1998 Dec; 72(12):9906-17.. View in PubMed
  • Infectivity and dynamics of HIV type 1 replication in the blood and reproductive tract of HIV type 1-infected women. AIDS Res Hum Retroviruses. 1998 Apr; 14.. View in PubMed
  • Genomic structure and nucleotide sequence analysis of a new HIV type 1 subtype A strain from Nigeria. AIDS Res Hum Retroviruses. 1996 Oct 10; 12(15):1413-25.. View in PubMed