Toby Maher, MD, PhD

Professor of Clinical Medicine

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Publications

  • Update of the international multidisciplinary classification of the interstitial pneumonias: an ERS/ATS statement. Eur Respir J. 2025 Dec; 66(6).. View in PubMed
  • Basement membrane repair response biomarker PRO-C4 predicts progression in idiopathic pulmonary fibrosis: analysis of the PFBIO and PROFILE cohorts. Thorax. 2025 Nov 14; 80(12):935-944.. View in PubMed
  • Development and validation of a predictive 6-min walk score in patients with idiopathic pulmonary fibrosis. Eur Respir J. 2025 Nov; 66(5).. View in PubMed
  • Effect of Admilparant, a Lysophosphatidic Acid Receptor 1 Antagonist, on Disease Progression in Pulmonary Fibrosis. Chest. 2025 Sep; 168(3):677-687.. View in PubMed
  • Artificial Intelligence and the Diagnosis of Interstitial Lung Disease: Are We Ready for ChatMDT?! Respirology. 2025 Aug; 30(8):689-690.. View in PubMed
  • Stratifying GAP Stages by MUC5B rs35705950 T-Allele Carriage Refines Survival Prediction in IPF. Lung. 2025 Jul 30; 203(1):85.. View in PubMed
  • Deupirfenidone (LYT-100) in post-acute sequelae of SARS-CoV-2 with respiratory complications. ERJ Open Res. 2025 Jul; 11(4).. View in PubMed
  • Fibrosis: cross-organ biology and pathways to development of innovative drugs. Nat Rev Drug Discov. 2025 07; 24(7):543-569.. View in PubMed
  • Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis. N Engl J Med. 2025 Jun 12; 392(22):2193-2202.. View in PubMed
  • Nerandomilast in Patients with Progressive Pulmonary Fibrosis. N Engl J Med. 2025 Jun 12; 392(22):2203-2214.. View in PubMed
  • Rare variants and survival of patients with idiopathic pulmonary fibrosis: analysis of a multicentre, observational cohort study with independent validation. Lancet Respir Med. 2025 Jun; 13(6):495-504.. View in PubMed
  • Predicting Failure: Can Blood Biomarkers Identify Likely Treatment Non-Responders in IPF? Respirology. 2025 Jun; 30(6):461-462.. View in PubMed
  • Phase 2 study design and analysis approach for BBT-877: an autotaxin inhibitor targeting idiopathic pulmonary fibrosis. BMJ Open Respir Res. 2025 May 22; 12(1).. View in PubMed
  • Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment. Lung. 2025 May 13; 203(1):62.. View in PubMed
  • Publisher Correction: Fibrosis: cross-organ biology and pathways to development of innovative drugs. Nat Rev Drug Discov. 2025 May; 24(5):399.. View in PubMed
  • Circulating prostasin is an independent marker of mortality risk in patients with idiopathic pulmonary fibrosis. ERJ Open Res. 2025 May; 11(3).. View in PubMed
  • The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial. BMJ Open. 2025 Feb 05; 15(2):e088604.. View in PubMed
  • Genome-wide association study of Idiopathic Pulmonary Fibrosis susceptibility using clinically-curated European-ancestry datasets. medRxiv. 2025 Feb 02.. View in PubMed
  • Efficacy and Safety of Admilparant, an LPA1 Antagonist, in Pulmonary Fibrosis: A Phase 2 Randomized Clinical Trial. Am J Respir Crit Care Med. 2025 Feb; 211(2):230-238.. View in PubMed
  • Design of CONQUEST, a novel, randomized, placebo-controlled, Phase 2b platform clinical trial to investigate new treatments for patients with early active systemic sclerosis with interstitial lung disease. J Scleroderma Relat Disord. 2024 Nov 05; 23971983241278079.. View in PubMed
  • Effects of nintedanib on circulating biomarkers of idiopathic pulmonary fibrosis. ERJ Open Res. 2024 Nov; 10(6).. View in PubMed
  • Rare variants and survival of patients with idiopathic pulmonary fibrosis. medRxiv. 2024 Oct 15.. View in PubMed
  • Competing Causes of Death in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 Oct 01; 210(7):938-940.. View in PubMed
  • Cluster analysis of blood biomarkers to identify molecular patterns in pulmonary fibrosis: assessment of a multicentre, prospective, observational cohort with independent validation. Lancet Respir Med. 2024 Sep; 12(9):681-692.. View in PubMed
  • The fibroblast hormone Endotrophin is a biomarker of mortality in chronic diseases. Matrix Biol. 2024 Sep; 132:1-9.. View in PubMed
  • The future of clinical trials in idiopathic pulmonary fibrosis. Curr Opin Pulm Med. 2024 Sep 01; 30(5):494-499.. View in PubMed
  • Type 1 Invariant Natural Killer T Cells Drive Lung Fibrosis. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):521-523.. View in PubMed
  • TOLLIP SNP and Antimicrobial Treatment Effect in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):508-511.. View in PubMed
  • Pioneering Research Driving Progress toward a Cure for Interstitial Lung Disease (ILD): Introduction to the AJRCCM Special Issue on ILD (Part 2). Am J Respir Crit Care Med. 2024 Aug 15; 210(4):373-374.. View in PubMed
  • Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):444-454.. View in PubMed
  • Deep Learning-based Segmentation of Computed Tomography Scans Predicts Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):465-472.. View in PubMed
  • Phase 2, Double-Blind, Placebo-controlled Trial of a c-Jun N-Terminal Kinase Inhibitor in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):435-443.. View in PubMed
  • Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):401-423.. View in PubMed
  • Modified blood cell GAP model as a prognostic biomarker in idiopathic pulmonary fibrosis. ERJ Open Res. 2024 Jul; 10(4).. View in PubMed
  • Potential of αvβ6 and αvβ1 integrin inhibition for treatment of idiopathic pulmonary fibrosis. Expert Opin Ther Targets. 2024 Jul; 28(7):575-585.. View in PubMed
  • Circulating biomarkers and progression of idiopathic pulmonary fibrosis: data from the INMARK trial. ERJ Open Res. 2024 Jul; 10(4).. View in PubMed
  • A comparison of respiratory oscillometry and spirometry in idiopathic pulmonary fibrosis: performance time, symptom burden and test-retest reliability. ERJ Open Res. 2024 Jul; 10(4).. View in PubMed
  • Association between mosaic loss of chromosome Y and pulmonary fibrosis susceptibility and severity. bioRxiv. 2024 May 30.. View in PubMed
  • Interstitial Lung Disease: A Review. JAMA. 2024 05 21; 331(19):1655-1665.. View in PubMed
  • Cough Severity Visual Analog Scale Assesses Cough Burden and Predicts Survival in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 05 01; 209(9):1165-1167.. View in PubMed
  • A Long and Winding Road: Drug Development in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 05 01; 209(9):1072-1073.. View in PubMed
  • Gazing into the Proteomic Crystal Ball: Predicting Survival in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2024 05 01; 209(9):1056-1057.. View in PubMed
  • Watching an Evolution in Progress, Cutting-Edge Research Transforming Outcomes in Interstitial Lung Disease: Introduction to an AJRCCM Special Issue. Am J Respir Crit Care Med. 2024 05 01; 209(9):1049-1050.. View in PubMed
  • [18F]FDG PET/CT Signal Correlates with Neoangiogenesis Markers in Patients with Fibrotic Interstitial Lung Disease Who Underwent Lung Biopsy: Implication for the Use of PET/CT in Diffuse Lung Diseases. J Nucl Med. 2024 Apr 01; 65(4):617-622.. View in PubMed
  • Morphine for treatment of cough in idiopathic pulmonary fibrosis (PACIFY COUGH): a prospective, multicentre, randomised, double-blind, placebo-controlled, two-way crossover trial. Lancet Respir Med. 2024 Apr; 12(4):273-280.. View in PubMed
  • Estimating the effect of nintedanib on forced vital capacity in children and adolescents with fibrosing interstitial lung disease using a Bayesian dynamic borrowing approach. Pediatr Pulmonol. 2024 Apr; 59(4):1038-1046.. View in PubMed
  • Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on ‘Feels, Functions, Survives’. Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency. Am J Respir Crit Care Med. 2024 03 15; 209(6):647-669.. View in PubMed
  • Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report. Am J Respir Crit Care Med. 2024 02 15; 209(4):362-373.. View in PubMed
  • Effects of nintedanib on symptoms in patients with progressive pulmonary fibrosis. Eur Respir J. 2024 Feb; 63(2).. View in PubMed
  • Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis. medRxiv. 2024 Jan 15.. View in PubMed
  • Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis. ERJ Open Res. 2024 Jan; 10(1).. View in PubMed
  • Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report. Ann Am Thorac Soc. 2024 Jan; 21(1):1-11.. View in PubMed
  • An adjudication algorithm for respiratory-related hospitalisation in idiopathic pulmonary fibrosis. ERJ Open Res. 2024 Jan; 10(1).. View in PubMed
  • Decline in forced vital capacity as a surrogate for mortality in patients with pulmonary fibrosis. Respirology. 2023 12; 28(12):1147-1153.. View in PubMed
  • Nocturnal Hypoxemia Associates With Symptom Progression and Mortality in Patients With Progressive Fibrotic Interstitial Lung Disease. Chest. 2023 11; 164(5):1232-1242.. View in PubMed
  • Combination of BAL and Computed Tomography Differentiates Progressive and Non-progressive Fibrotic Lung Diseases. Am J Respir Crit Care Med. 2023 11 01; 208(9):975-982.. View in PubMed
  • Gastrointestinal pirfenidone adverse events in idiopathic pulmonary fibrosis depending on diet: the MADIET clinical trial. Eur Respir J. 2023 10; 62(4).. View in PubMed
  • Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis. Nat Commun. 2023 09 27; 14(1):6039.. View in PubMed
  • Ziritaxestat and Lung Function in Idiopathic Pulmonary Fibrosis-Reply. JAMA. 2023 09 12; 330(10):973-974.. View in PubMed
  • Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with progressive pulmonary fibrosis (FIBRONEER-ILD). BMJ Open Respir Res. 2023 09; 10(1).. View in PubMed
  • The Burden and Impact of Cough in Patients with Idiopathic Pulmonary Fibrosis: An Analysis of the Prospective Observational PROFILE Study. Ann Am Thorac Soc. 2023 09; 20(9):1267-1273.. View in PubMed
  • Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis. NEJM Evid. 2023 Aug; 2(8):EVIDoa2300083.. View in PubMed
  • Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF). BMJ Open Respir Res. 2023 08; 10(1).. View in PubMed
  • Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis. medRxiv. 2023 Jul 24.. View in PubMed
  • Airway soluble CSF1R predicts progression in patients with idiopathic pulmonary fibrosis. ERJ Open Res. 2023 Jul; 9(4).. View in PubMed
  • Change in gait speed and adverse outcomes in patients with idiopathic pulmonary fibrosis: A prospective cohort study. Respirology. 2023 07; 28(7):649-658.. View in PubMed
  • PCSK6 and Survival in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2023 06 01; 207(11):1515-1524.. View in PubMed
  • Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis. Thorax. 2023 06; 78(6):551-558.. View in PubMed
  • Knowledge gaps in fibrotic interstitial lung disease in pan-Asian populations: data not missing at random? Lancet Respir Med. 2023 06; 11(6):502-504.. View in PubMed
  • Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials. JAMA. 2023 05 09; 329(18):1567-1578.. View in PubMed
  • Extent of fibrosis and lung function decline in patients with systemic sclerosis and interstitial lung disease: data from the SENSCIS trial. Rheumatology (Oxford). 2023 05 02; 62(5):1870-1876.. View in PubMed
  • Systemic sclerosis associated interstitial lung disease: a conceptual framework for subclinical, clinical and progressive disease. Rheumatology (Oxford). 2023 05 02; 62(5):1877-1886.. View in PubMed
  • Clinical trial simulations in pulmonary fibrosis: patient-focused insights and adaptations. ERJ Open Res. 2023 May; 9(3).. View in PubMed
  • MUC5B rs35705950 minor allele associates with older age and better survival in idiopathic pulmonary fibrosis. Respirology. 2023 05; 28(5):455-464.. View in PubMed
  • Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. Am J Respir Crit Care Med. 2023 05 01; 207(9):1194-1202.. View in PubMed
  • The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study. Eur Respir J. 2023 05; 61(5).. View in PubMed
  • Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis. Eur Respir Rev. 2023 Mar 31; 32(167).. View in PubMed
  • Weight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial. Respir Res. 2023 Mar 09; 24(1):71.. View in PubMed
  • GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial. Eur Respir J. 2023 03; 61(3).. View in PubMed
  • Impact of lung function and baseline clinical characteristics on patient-reported outcome measures in systemic sclerosis-associated interstitial lung disease. Rheumatology (Oxford). 2023 02 06; 62(SI):SI43-SI53.. View in PubMed
  • Effect of nintedanib in patients with systemic sclerosis-associated interstitial lung disease and risk factors for rapid progression. RMD Open. 2023 02; 9(1).. View in PubMed
  • Home monitoring in interstitial lung diseases. Lancet Respir Med. 2023 01; 11(1):97-110.. View in PubMed
  • Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial. Lancet Respir Med. 2023 01; 11(1):45-54.. View in PubMed
  • Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study. Lancet Respir Med. 2023 01; 11(1):65-73.. View in PubMed
  • Plain language summary: Clinical study of BI 1015550 as a potential treatment for idiopathic pulmonary fibrosis. J Comp Eff Res. 2022 Dec 20.. View in PubMed
  • Forced vital capacity trajectories in patients with idiopathic pulmonary fibrosis: a secondary analysis of a multicentre, prospective, observational cohort. Lancet Digit Health. 2022 12; 4(12):e862-e872.. View in PubMed
  • Thoracic Involvement in Systemic Autoimmune Rheumatic Diseases: Pathogenesis and Management. Clin Rev Allergy Immunol. 2022 Dec; 63(3):472-489.. View in PubMed
  • Tackling the Neuropathic Cough of Idiopathic Pulmonary Fibrosis (IPF): More Needs to be Done. Lung. 2022 12; 200(6):673-675.. View in PubMed
  • A review of the challenges, learnings and future directions of home handheld spirometry in interstitial lung disease. Respir Res. 2022 Nov 11; 23(1):307.. View in PubMed
  • A clinical short-cut to identifying short telomeres in idiopathic pulmonary fibrosis? Respirology. 2022 11; 27(11):916-917.. View in PubMed
  • Genome-wide Enrichment of TERT Rare Variants in Idiopathic Pulmonary Fibrosis Patients of Latino Ancestry. Am J Respir Crit Care Med. 2022 10 01; 206(7):903-905.. View in PubMed
  • Effect of Nintedanib on Progression of Systemic Sclerosis-Associated Interstitial Lung Disease Over 100 Weeks: Data From a Randomized Controlled Trial. ACR Open Rheumatol. 2022 Oct; 4(10):837-844.. View in PubMed
  • Phase I studies of BI 1015550, a preferential phosphodiesterase 4B inhibitor, in healthy males and patients with idiopathic pulmonary fibrosis. ERJ Open Res. 2022 Oct; 8(4).. View in PubMed
  • Diagnosis and monitoring of systemic sclerosis-associated interstitial lung disease using high-resolution computed tomography. J Scleroderma Relat Disord. 2022 Oct; 7(3):168-178.. View in PubMed
  • Interstitial lung diseases. Lancet. 2022 09 03; 400(10354):769-786.. View in PubMed
  • Reply to Fujimoto et al.: The Need for a CYFRA 21-1 Cutoff Value to Predict Clinical Progression of IPF in Clinical Practice. Am J Respir Crit Care Med. 2022 09 01; 206(5):649-650.. View in PubMed
  • The role of precision medicine in interstitial lung disease. Eur Respir J. 2022 Sep; 60(3).. View in PubMed
  • Trial of a Phosphodiesterase 4 Inhibitor for Idiopathic Pulmonary Fibrosis. Reply. N Engl J Med. 2022 08 25; 387(8):762.. View in PubMed
  • Integrating Clinical Probability into the Diagnostic Approach to Idiopathic Pulmonary Fibrosis: An International Working Group Perspective. Am J Respir Crit Care Med. 2022 08 01; 206(3):247-259.. View in PubMed
  • Biomarkers for Interstitial Lung Abnormalities: A Stepping-stone Toward Idiopathic Pulmonary Fibrosis Prevention? Am J Respir Crit Care Med. 2022 08 01; 206(3):244-246.. View in PubMed
  • Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis. Thorax. 2022 08; 77(8):829-833.. View in PubMed
  • Decline in forced vital capacity in subjects with systemic sclerosis-associated interstitial lung disease in the SENSCIS trial compared with healthy reference subjects. Respir Res. 2022 Jul 05; 23(1):178.. View in PubMed
  • Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 07 01; 206(1):56-69.. View in PubMed
  • Meta-Analysis of Effect of Nintedanib on Reducing FVC Decline Across Interstitial Lung Diseases. Adv Ther. 2022 07; 39(7):3392-3402.. View in PubMed
  • CYFRA 21-1 Predicts Progression in Idiopathic Pulmonary Fibrosis: A Prospective Longitudinal Analysis of the PROFILE Cohort. Am J Respir Crit Care Med. 2022 06 15; 205(12):1440-1448.. View in PubMed
  • Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis. N Engl J Med. 2022 06 09; 386(23):2178-2187.. View in PubMed
  • Lung function trajectory in progressive fibrosing interstitial lung disease. Eur Respir J. 2022 06; 59(6).. View in PubMed
  • Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2022 05 01; 205(9):e18-e47.. View in PubMed
  • Phase 2B Study of Inhaled RVT-1601 for Chronic Cough in Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized, Placebo-controlled Study (SCENIC Trial). Am J Respir Crit Care Med. 2022 05 01; 205(9):1084-1092.. View in PubMed
  • Fatum Inexorabile: Do Monocytes Predict the Fate of Interstitial Lung Abnormalities? Am J Respir Crit Care Med. 2022 04 01; 205(7):743-744.. View in PubMed
  • PAciFy Cough-a multicentre, double-blind, placebo-controlled, crossover trial of morphine sulphate for the treatment of pulmonary Fibrosis Cough. Trials. 2022 Mar 02; 23(1):184.. View in PubMed
  • Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis and COPD: A Propensity-Matched Real-World Study. Chest. 2022 03; 161(3):728-737.. View in PubMed
  • Biomarker signatures for progressive idiopathic pulmonary fibrosis. Eur Respir J. 2022 03; 59(3).. View in PubMed
  • Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 03 01; 205(5):550-562.. View in PubMed
  • Clinical Utility of Home versus Hospital Spirometry in Fibrotic Interstitial Lung Disease: Evaluation after INJUSTIS Interim Analysis. Ann Am Thorac Soc. 2022 03; 19(3):506-509.. View in PubMed
  • Short-term lung function changes predict mortality in patients with fibrotic hypersensitivity pneumonitis. Respirology. 2022 03; 27(3):202-208.. View in PubMed
  • Using Data on Survival with Idiopathic Pulmonary Fibrosis to Estimate Survival with Other Types of Progressive Fibrosis Interstitial Lung Disease: A Bayesian Framework. Adv Ther. 2022 02; 39(2):1045-1054.. View in PubMed
  • Effects of nintedanib by inclusion criteria for progression of interstitial lung disease. Eur Respir J. 2022 02; 59(2).. View in PubMed
  • Pirfenidone in Unclassifiable Interstitial Lung Disease: A Subgroup Analysis by Concomitant Mycophenolate Mofetil and/or Previous Corticosteroid Use. Adv Ther. 2022 02; 39(2):1081-1095.. View in PubMed
  • Efficacy of Pirfenidone vs. Placebo in Unclassifiable Interstitial Lung Disease, by Surgical Lung Biopsy Status: Data From a post-hoc Analysis. Front Med (Lausanne). 2022; 9:897102.. View in PubMed
  • Autoantibodies are present in the bronchoalveolar lavage but not circulation in patients with fibrotic interstitial lung disease. ERJ Open Res. 2022 Jan; 8(1).. View in PubMed
  • Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD). BMJ Open Respir Res. 2021 Dec; 8(1).. View in PubMed
  • Reply. Arthritis Rheumatol. 2021 12; 73(12):2354-2355.. View in PubMed
  • Small Airways in Idiopathic Pulmonary Fibrosis: Quiet but Not Forgotten. Am J Respir Crit Care Med. 2021 11 01; 204(9):1010-1011.. View in PubMed
  • DNA Methylome Alterations Are Associated with Airway Macrophage Differentiation and Phenotype during Lung Fibrosis. Am J Respir Crit Care Med. 2021 10 15; 204(8):954-966.. View in PubMed
  • Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: an F-MISO PET/CT study. Eur Respir J. 2021 10; 58(4).. View in PubMed
  • Targeting Human Herpesviruses: An Effective Strategy for Treating Idiopathic Pulmonary Fibrosis? Ann Am Thorac Soc. 2021 08; 18(8):1285-1286.. View in PubMed
  • Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells. Am J Respir Crit Care Med. 2021 07 15; 204(2):197-208.. View in PubMed
  • Patient-centered Outcomes Research in Interstitial Lung Disease: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2021 07 15; 204(2):e3-e23.. View in PubMed
  • Global incidence and prevalence of idiopathic pulmonary fibrosis. Respir Res. 2021 Jul 07; 22(1):197.. View in PubMed
  • Home spirometry in patients with idiopathic pulmonary fibrosis: data from the INMARK trial. Eur Respir J. 2021 07; 58(1).. View in PubMed
  • Worldwide experiences and opinions of healthcare providers on eHealth for patients with interstitial lung diseases in the COVID-19 era. ERJ Open Res. 2021 Jul; 7(3).. View in PubMed
  • Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis. Eur Respir J. 2021 07; 58(1).. View in PubMed
  • Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 07 01; 204(1):74-81.. View in PubMed
  • 50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study. EBioMedicine. 2021 Jul; 69:103439.. View in PubMed
  • Muscle stimulation in advanced idiopathic pulmonary fibrosis: a randomised placebo-controlled feasibility study. BMJ Open. 2021 06 02; 11(6):e048808.. View in PubMed
  • Idiopathic pulmonary fibrosis: Disease mechanisms and drug development. Pharmacol Ther. 2021 06; 222:107798.. View in PubMed
  • Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis. Eur Respir J. 2021 05; 57(5).. View in PubMed
  • Serum markers of pulmonary epithelial damage in systemic sclerosis-associated interstitial lung disease and disease progression. Respirology. 2021 05; 26(5):461-468.. View in PubMed
  • Effect of Nintedanib on Lung Function in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease: Further Analyses of a Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis Rheumatol. 2021 04; 73(4):671-676.. View in PubMed
  • Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis. Commun Biol. 2021 03 23; 4(1):392.. View in PubMed
  • Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations. Am J Respir Crit Care Med. 2021 03 15; 203(6):775-778.. View in PubMed
  • Can biomarkers of extracellular matrix remodelling and wound healing be used to identify high risk patients infected with SARS-CoV-2?: lessons learned from pulmonary fibrosis. Respir Res. 2021 Feb 05; 22(1):38.. View in PubMed
  • The Respiratory Microbiome in Chronic Hypersensitivity Pneumonitis Is Distinct from That of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 02 01; 203(3):339-347.. View in PubMed
  • Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis. Eur Respir J. 2021 02; 57(2).. View in PubMed
  • Efficacy and safety of nintedanib in patients with systemic sclerosis-associated interstitial lung disease treated with mycophenolate: a subgroup analysis of the SENSCIS trial. Lancet Respir Med. 2021 01; 9(1):96-106.. View in PubMed
  • Assessment of recent evidence for the management of patients with systemic sclerosis-associated interstitial lung disease: a systematic review. ERJ Open Res. 2021 Jan; 7(1).. View in PubMed
  • Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis. Thorax. 2021 01; 76(1):73-82.. View in PubMed
  • Management of Acute Exacerbation of Idiopathic Pulmonary Fibrosis in Specialised and Non-specialised ILD Centres Around the World. Front Med (Lausanne). 2021; 8:699644.. View in PubMed
  • Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis. Front Immunol. 2021; 12:661811.. View in PubMed
  • BAL Is Safe and Well Tolerated in Individuals with Idiopathic Pulmonary Fibrosis: An Analysis of the PROFILE Study. Am J Respir Crit Care Med. 2021 01 01; 203(1):136-139.. View in PubMed
  • Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis: The EME-TIPAC Randomized Clinical Trial. JAMA. 2020 12 08; 324(22):2282-2291.. View in PubMed
  • Opportunities to diagnose fibrotic lung diseases in routine care: A primary care cohort study. Respirology. 2020 12; 25(12):1274-1282.. View in PubMed
  • Safety and tolerability of nintedanib in patients with systemic sclerosis-associated interstitial lung disease: data from the SENSCIS trial. Ann Rheum Dis. 2020 11; 79(11):1478-1484.. View in PubMed
  • Mixed Ventilatory Defects in Pulmonary Sarcoidosis: Prevalence and Clinical Features. Chest. 2020 11; 158(5):2007-2014.. View in PubMed
  • Itaconate controls the severity of pulmonary fibrosis. Sci Immunol. 2020 Oct 23; 5(52).. View in PubMed
  • Interaction between the promoter MUC5B polymorphism and mucin expression: is there a difference according to ILD subtype? Thorax. 2020 10; 75(10):901-903.. View in PubMed
  • Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis. Nat Commun. 2020 09 16; 11(1):4659.. View in PubMed
  • Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nat Commun. 2020 Sep 11; 11(1):4680.. View in PubMed
  • Shedding light on developmental drugs for idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug; 29(8):797-808.. View in PubMed
  • Diagnostic and Prognostic Biomarkers for Chronic Fibrosing Interstitial Lung Diseases With a Progressive Phenotype. Chest. 2020 08; 158(2):646-659.. View in PubMed
  • Pulmonary fibrosis secondary to COVID-19: a call to arms? Lancet Respir Med. 2020 08; 8(8):750-752.. View in PubMed
  • The need for a holistic approach for SSc-ILD – achievements and ambiguity in a devastating disease. Respir Res. 2020 Jul 23; 21(1):197.. View in PubMed
  • Healthcare Resources Utilization and Costs of Patients with Non-IPF Progressive Fibrosing Interstitial Lung Disease Based on Insurance Claims in the USA. Adv Ther. 2020 07; 37(7):3292-3298.. View in PubMed
  • Pleuroparenchymal fibroelastosis in systemic sclerosis: prevalence and prognostic impact. Eur Respir J. 2020 07; 56(1).. View in PubMed
  • Chronic hypersensitivity pneumonitis; an enigmatic and frequently fatal disease. Eur Respir Rev. 2020 Jun 30; 29(156).. View in PubMed
  • European consensus statements for interstitial lung disease in systemic sclerosis – Authors’ reply. Lancet Rheumatol. 2020 Jun; 2(6):e319-e320.. View in PubMed
  • Predictors of progression in systemic sclerosis patients with interstitial lung disease. Eur Respir J. 2020 05; 55(5).. View in PubMed
  • Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis. A Call to Arms. Am J Respir Crit Care Med. 2020 05 01; 201(9):1030-1032.. View in PubMed
  • Healthcare Resource Utilization Among Patients in England with Systemic Sclerosis-Associated Interstitial Lung Disease: A Retrospective Database Analysis. Adv Ther. 2020 05; 37(5):2460-2476.. View in PubMed
  • Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease. Clin Rheumatol. 2020 Apr; 39(4):1173-1179.. View in PubMed
  • Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent. Eur Respir J. 2020 04; 55(4).. View in PubMed
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