Keck School Faculty

Trevor Angell

Trevor Angell

Assistant Professor of Clinical Medicine
Associate Medical Director of Thyroid Center
BMT B11 Off Campus Los Angeles

Changes in Stage Distribution and Disease-Specific Survival in Differentiated Thyroid Cancer with Transition to American Joint Committee on Cancer 8th Edition: A Systematic Review and Meta-Analysis Oncologist. 2020 Aug 30. . View in PubMed

Completion Thyroidectomy is Less Common Following Updated 2015 American Thyroid Association Guidelines Ann Surg Oncol. 2020 Jun 24. . View in PubMed

Use of Molecular Diagnostic Tests in Thyroid Nodules with Hürthle Cell-Dominant Cytology Thyroid. 2020 May 04. . View in PubMed

Insights From a Real-World Study of Molecular Test Performance for Indeterminate Thyroid Nodules J Clin Endocrinol Metab. 2020 Apr 01; 105(4). . View in PubMed

Treatment of Differentiated Thyroid Carcinomas Surg Pathol Clin. 2019 Dec; 12(4):931-942. . View in PubMed

Getting more out of molecular testing for indeterminate thyroid nodules Cancer Cytopathol. 2019 Sep; 127(9):555-556. . View in PubMed

The Impact of Hashimoto Thyroiditis on Thyroid Nodule Cytology and Risk of Thyroid Cancer J Endocr Soc. 2019 Apr 01; 3(4):791-800. . View in PubMed

Tall Cell Variant of Papillary Thyroid Carcinoma: Impact of Change in WHO Definition and Molecular Analysis Endocr Pathol. 2019 Mar; 30(1):43-48. . View in PubMed

Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules Thyroid. 2019 11; 29(11):1594-1605. . View in PubMed


Thyroid Nodules and Thyroid Cancer in the Pregnant Woman Endocrinol Metab Clin North Am. 2019 09; 48(3):557-567. . View in PubMed

Differences in Thyroid Nodule Cytology and Malignancy Risk Between Children and Adults Thyroid. 2019 08; 29(8):1097-1104. . View in PubMed

The Impact of High-Dose Glucocorticoids on the Outcome of Immune-Checkpoint Inhibitor-Related Thyroid Disorders Cancer Immunol Res. 2019 07; 7(7):1214-1220. . View in PubMed

Independent Comparison of the Afirma Genomic Sequencing Classifier and Gene Expression Classifier for Cytologically Indeterminate Thyroid Nodules Thyroid. 2019 05; 29(5):650-656. . View in PubMed

Analytical and Clinical Validation of Expressed Variants and Fusions From the Whole Transcriptome of Thyroid FNA Samples Front Endocrinol (Lausanne). 2019; 10:612. . View in PubMed

A Cohort Analysis of Clinical and Ultrasound Variables Predicting Cancer Risk in 20,001 Consecutive Thyroid Nodules J Clin Endocrinol Metab. 2019 11 01; 104(11):5665-5672. . View in PubMed

Effect of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) on Malignancy Rates in Thyroid Nodules: How to Counsel Patients on Extent of Surgery Ann Surg Oncol. 2019 Jan; 26(1):93-97. . View in PubMed


Reasons Associated with Total Thyroidectomy as Initial Surgical Management of an Indeterminate Thyroid Nodule Ann Surg Oncol. 2018 May; 25(5):1410-1417. . View in PubMed

Unique Cytologic Features of Thyroiditis Caused by Immune Checkpoint Inhibitor Therapy for Malignant Melanoma Genes Dis. 2018 Mar; 5(1):46-48. . View in PubMed

Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Endocr Pathol. 2018 Mar; 29(1):68-74. . View in PubMed

Risk Factors for New Hypothyroidism During Tyrosine Kinase Inhibitor Therapy in Advanced Nonthyroidal Cancer Patients Thyroid. 2018 04; 28(4):437-444. . View in PubMed

Quantitative Analysis of the Benefits and Risk of Thyroid Nodule Evaluation in Patients =70 Years Old Thyroid. 2018 04; 28(4):465-471. . View in PubMed

Hypothyroidism During Tyrosine Kinase Inhibitor Therapy Is Associated with Longer Survival in Patients with Advanced Nonthyroidal Cancers Thyroid. 2018 04; 28(4):445-453. . View in PubMed

Natural History and Outcomes of Cytologically Benign Thyroid Nodules in Children J Clin Endocrinol Metab. 2018 09 01; 103(9):3557-3565. . View in PubMed

Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules JAMA Surg. 2018 09 01; 153(9):817-824. . View in PubMed

A modified reporting approach for thyroid FNA in the NIFTP era: A 1-year institutional experience Cancer Cytopathol. 2017 Nov; 125(11):854-864. . View in PubMed

RAS-positive thyroid nodules Curr Opin Endocrinol Diabetes Obes. 2017 Oct; 24(5):372-376. . View in PubMed

The Flip Side of NIFTP: an Increase in Rates of Unfavorable Histologic Parameters in the Remainder of Papillary Thyroid Carcinomas Endocr Pathol. 2017 Jun; 28(2):171-176. . View in PubMed

Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes Cancer Cytopathol. 2017 05; 125(5):313-322. . View in PubMed

Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features Accounts for More Than Half of "Carcinomas" Harboring RAS Mutations Thyroid. 2017 04; 27(4):506-511. . View in PubMed

Differential Growth Rates of Benign vsMalignant Thyroid Nodules. J Clin Endocrinol Metab. 2017 12 01; 102(12):4642-4647. . View in PubMed

Circulating Myeloid-Derived Suppressor Cells Predict Differentiated Thyroid Cancer Diagnosis and Extent Thyroid. 2016 Mar; 26(3):381-9. . View in PubMed

Bethesda Categorization of Thyroid Nodule Cytology and Prediction of Thyroid Cancer Type and Prognosis Thyroid. 2016 Feb; 26(2):256-61. . View in PubMed

Long- versus short-interval follow-up of cytologically benign thyroid nodules: a prospective cohort study BMC Med. 2016 Jan 27; 14:11. . View in PubMed

Clinical, Sonographic, and Pathological Characteristics of RAS-Positive Versus BRAF-Positive Thyroid Carcinoma J Clin Endocrinol Metab. 2016 12; 101(12):4938-4944. . View in PubMed

Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier Thyroid. 2016 07; 26(7):911-5. . View in PubMed


The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and Thyroid Cancer Risk J Clin Endocrinol Metab. 2015 Dec; 100(12):4434-40. . View in PubMed

Afirma Benign Thyroid Nodules Show Similar Growth to Cytologically Benign Nodules During Follow-Up J Clin Endocrinol Metab. 2015 Nov; 100(11):E1477-83. . View in PubMed

Localized LECT2 amyloidosis of the adrenal gland with coexisting MGUS: a diagnostic challenge Ann Hematol. 2015 Sep; 94(9):1603-4. . View in PubMed

The variable phenotype and low-risk nature of RAS-positive thyroid nodules BMC Med. 2015 Aug 07; 13:184. . View in PubMed

Clinical features and hospital outcomes in thyroid storm: a retrospective cohort study J Clin Endocrinol Metab. 2015 Feb; 100(2):451-9. . View in PubMed

MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro Clin Cancer Res. 2014 Dec 01; 20(23):6034-44. . View in PubMed

BRAF V600E in papillary thyroid carcinoma is associated with increased programmed death ligand 1 expression and suppressive immune cell infiltration Thyroid. 2014 Sep; 24(9):1385-93. . View in PubMed

In search of an unstimulated thyroglobulin baseline value in low-risk papillary thyroid carcinoma patients not receiving radioactive iodine ablation Thyroid. 2014 Jul; 24(7):1127-33. . View in PubMed

Trevor E Angell, MD is an Assistant Professor of clinical medicine in the Department of Medicine’s division of endocrinology, diabetes and metabolism at Keck School of Medicine of USC.

Dr. Angell is board certified in internal medicine and diabetes, endocrinology and metabolism. His clinical and research interests are related to the diagnosis and treatment of thyroid diseases. He has receiving funding for his research predicting thyroid cancer in patients with thyroid nodules from the Thyroid Cancer Survivors' Association (American Thyroid Association Research Grant) and Harvard Medical School scholars in medicine program.

He has published articles in JAMA Surgery, Thyroid, The Journal of Clinical Endocrinology and Metabolism, and Current Opinion in Endocrinology and Diabetes, including original research and invited reviews. He is on the editorial board of Frontiers in Endocrinology and is a member of the Endocrine Society and the American Thyroid Association where he serves as the Co-Chair of the Patient Affairs and Education Committee.

After finishing his clinical and research training at the Keck School of Medicine and the Los Angeles County-USC Medical Center, Dr. Angell went to work as an instructor in medicine and the Brigham and Women’s Hospital and Harvard Medical School in 2014 performing patient care, residents and fellow teaching, and research. Dr. Angell is recognized for clinical expertise in thyroid nodules, thyroid cancer, thyroid hormone dysfunction, and thyroid disorders during pregnancy. He is nationally known for research into thyroid nodule evaluation and molecular testing of thyroid nodules. In 2018, Dr. Angell joined the faculty at the Keck School of Medicine.
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