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Unmesh Jadhav

Assistant Professor of Stem Cell Biology and Regenerative Medicine

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Phone +1 323 442 2563
Email ujadhav@usc.edu
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Publications

  • Crypt density and recruited enhancers underlie intestinal tumour initiation Nature. 2025 Apr; 640(8057):231-239. . View in PubMed
  • Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis Nat Commun. 2025 Jan 22; 16(1):929. . View in PubMed
  • DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes bioRxiv. 2024 Mar 07. . View in PubMed
  • Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer Nature. 2023 04; 616(7956):339-347. . View in PubMed
  • Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation Gastroenterology. 2021 06; 160(7):2267-2282. . View in PubMed
  • Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised PromotersMol Cell. 2020 04 02; 78(1):141-151. e5. . View in PubMed
  • Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNAMol Cell. 2019 05 02; 74(3):542-554. e5. . View in PubMed
  • Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development Genes Dev. 2018 11 01; 32(21-22):1430-1442. . View in PubMed
  • Transcription factor-dependent ‘anti-repressive’ mammalian enhancers exclude H3K27me3 from extended genomic domains Genes Dev. 2017 12 01; 31(23-24):2391-2404. . View in PubMed
  • Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells Cell. 2016 Jun 02; 165(6):1389-1400. . View in PubMed

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