Woojin An
Contact
Non-canonical MLL1 activity regulates centromeric phase separation and genome stability Nat Cell Biol. 2023 Nov; 25(11):1637-1649. . View in PubMed
VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation Biomedicines. 2023 Sep 17; 11(9). . View in PubMed
VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation Oncogene. 2023 04; 42(17):1405-1416. . View in PubMed
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer Nat Commun. 2023 04 17; 14(1):2140. . View in PubMed
MMP-9 drives the melanomagenic transcription program through histone H3 tail proteolysis Oncogene. 2022 01; 41(4):560-570. . View in PubMed
DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma Cancer Lett. 2022 11 01; 548:215899. . View in PubMed
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer Mol Oncol. 2021 10; 15(10):2801-2817. . View in PubMed
Insight Into Pathological Integrin aIIbß3 Activation From Safeguarding The Inactive State J Mol Biol. 2021 04 02; 433(7):166832. . View in PubMed
MMP-2 is a novel histone H3 N-terminal protease necessary for myogenic gene activation Epigenetics Chromatin. 2021 05 17; 14(1):23. . View in PubMed
A HOTAIR regulatory element modulates glioma cell sensitivity to temozolomide through long-range regulation of multiple target genes Genome Res. 2020 02; 30(2):155-163. . View in PubMed
Epigenetic Modification as a Regulatory Mechanism for Spatiotemporal Dynamics of ANO1 Expression in Salivary Glands Int J Mol Sci. 2019 Dec 13; 20(24). . View in PubMed
p32 is a negative regulator of p53 tetramerization and transactivation Mol Oncol. 2019 09; 13(9):1976-1992. . View in PubMed
DNMT and HDAC inhibitors modulate MMP-9-dependent H3 N-terminal tail proteolysis and osteoclastogenesis Epigenetics Chromatin. 2019 04 16; 12(1):25. . View in PubMed
MacroH2A12 inhibits prostate cancer-induced osteoclastogenesis through cooperation with HP1a and H1. 2. Oncogene. 2018 10; 37(43):5749-5765. . View in PubMed
Membrane Anchoring of a-Helical Proteins: Role of Tryptophan J Phys Chem B. 2018 01 25; 122(3):1185-1194. . View in PubMed
H3K27me1 is essential for MMP-9-dependent H3N-terminal tail proteolysis during osteoclastogenesis Epigenetics Chromatin. 2018 05 28; 11(1):23. . View in PubMed
Regulation of Breast Cancer-Induced Osteoclastogenesis by MacroH2A12 Involving EZH2-Mediated H3K27me3. Cell Rep. 2018 07 03; 24(1):224-237. . View in PubMed
Correction for Kim et al, "Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail". Mol Cell Biol. 2017 08 01; 37(15). . View in PubMed
Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing Proc Natl Acad Sci U S A. 2017 09 19; 114(38):E7949-E7958. . View in PubMed
MMP-9 facilitates selective proteolysis of the histone H3 tail at genes necessary for proficient osteoclastogenesis Genes Dev. 2016 Jan 15; 30(2):208-19. . View in PubMed
A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors J Biol Chem. 2016 08 19; 291(34):17536-46. . View in PubMed
Linker histone H12 establishes chromatin compaction and gene silencing through recognition of H3K27me3. Sci Rep. 2015 Nov 19; 5:16714. . View in PubMed
Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells Nucleic Acids Res. 2015 Oct 15; 43(18):8868-83. . View in PubMed
Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions Sci Rep. 2015 Oct 05; 5:14558. . View in PubMed
Linker Histone H12 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation. Cell Rep. 2013 Dec 26; 5(6):1690-703. . View in PubMed
VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription Mol Cell. 2013 Nov 07; 52(3):459-67. . View in PubMed
The histone variant MacroH2A regulates Ca(2+) influx through TRPC3 and TRPC6 channels Oncogenesis. 2013 Oct 28; 2:e77. . View in PubMed
Gene dysregulation by histone variant H2AZ in bladder cancer. Epigenetics Chromatin. 2013 Oct 16; 6(1):34. . View in PubMed
Biological implications and regulatory mechanisms of long-range chromosomal interactions J Biol Chem. 2013 Aug 02; 288(31):22369-77. . View in PubMed
Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency Cell Stem Cell. 2013 Jul 03; 13(1):36-47. . View in PubMed
Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1 Oncogene. 2013 May 16; 32(20):2510-20. . View in PubMed
Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy Nucleic Acids Res. 2013 09; 41(16):7656-72. . View in PubMed
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells Sci Rep. 2013; 3:1588. . View in PubMed
Functional interplay between p53 acetylation and H12 phosphorylation in p53-regulated transcription. Oncogene. 2012 Sep 27; 31(39):4290-301. . View in PubMed
An essential role of variant histone H33 for ectomesenchyme potential of the cranial neural crest. PLoS Genet. 2012 Sep; 8(9):e1002938. . View in PubMed
p53 requires an intact C-terminal domain for DNA binding and transactivation J Mol Biol. 2012 Feb 03; 415(5):843-54. . View in PubMed
Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail Mol Cell Biol. 2012 Feb; 32(4):783-96. . View in PubMed
Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation Nat Struct Mol Biol. 2011 Nov 13; 18(12):1358-65. . View in PubMed
Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing Nucleic Acids Res. 2011 Nov; 39(21):9167-80. . View in PubMed
3 stimulates HSP70 transcription through cooperation with HP1? . Nucleic Acids Res. 2011 Oct; 39(19):8329-41.. View in PubMed
Identification of preferential target sites for human DNA methyltransferases Nucleic Acids Res. 2011 Jan; 39(1):104-18. . View in PubMed
Cooperative action of TIP48 and TIP49 in H2AZ exchange catalyzed by acetylation of nucleosomal H2A. Nucleic Acids Res. 2009 Oct; 37(18):5993-6007. . View in PubMed
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription J Biol Chem. 2009 Jul 24; 284(30):19867-77. . View in PubMed
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction J Mol Biol. 2008 Sep 12; 381(4):816-25. . View in PubMed
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes Mol Cell. 2008 Aug 22; 31(4):510-519. . View in PubMed
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16 Mol Cell. 2008 Apr 11; 30(1):86-97. . View in PubMed
Isolation and characterization of a novel H12 complex that acts as a repressor of p53-mediated transcription. J Biol Chem. 2008 Apr 04; 283(14):9113-26. . View in PubMed
Purification and characterization of cellular proteins associated with histone H4 tails J Biol Chem. 2007 Jul 20; 282(29):21024-31. . View in PubMed
Isolation and characterization of proteins associated with histone H3 tails in vivo J Biol Chem. 2007 May 25; 282(21):15476-83. . View in PubMed
Histone acetylation and methylation: combinatorial players for transcriptional regulation Subcell Biochem. 2007; 41:351-69. . View in PubMed
Mechanism of polymerase II transcription repression by the histone variant macroH2A Mol Cell Biol. 2006 Feb; 26(3):1156-64. . View in PubMed
SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays EMBO J. 2004 Oct 01; 23(19):3815-24. . View in PubMed
Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53 Cell. 2004 Jun 11; 117(6):735-48. . View in PubMed
Regulation of the p300 HAT domain via a novel activation loop Nat Struct Mol Biol. 2004 Apr; 11(4):308-15. . View in PubMed
Reconstitution and transcriptional analysis of chromatin in vitro Methods Enzymol. 2004; 377:460-74. . View in PubMed
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression Mol Cell. 2003 Aug; 12(2):475-87. . View in PubMed
Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin Mol Cell. 2002 Apr; 9(4):811-21. . View in PubMed
SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones J Biol Chem. 2002 Feb 15; 277(7):5498-505. . View in PubMed
Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300 Mol Cell. 2000 Sep; 6(3):551-61. . View in PubMed
The site of binding of linker histone to the nucleosome does not depend upon the amino termini of core histones Biochimie. 1999 Jul; 81(7):727-32. . View in PubMed
The non-histone chromatin protein HMG1 protects linker DNA on the side opposite to that protected by linker histones J Biol Chem. 1998 Oct 09; 273(41):26289-91. . View in PubMed
Linker histone protection of chromatosomes reconstituted on 5S rDNA from Xenopus borealis:a reinvestigation Nucleic Acids Res. 1998 Sep 01; 26(17):4042-6. . View in PubMed
Linker histone protects linker DNA on only one side of the core particle and in a sequence-dependent manner Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3396-401. . View in PubMed