Xenos Mason, MD

Assistant Professor of Clinical Neurological Surgery and Neurology

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Xenos Mason M.D. is a neurologist and movement disorders specialist, with special interest and expertise in the use of Deep Brain Stimulation (DBS) for the treatment of movement disorders. His current research focuses on procedural therapies for movement disorders, in particular DBS. In collaboration with the USC Laboratory for Neuroimaging (LONI), Dr. Mason is studying connectomic biomarkers of DBS efficacy for Dystonia and other movement disorders. He is interested in the development of novel neuroimaging and neurophysiologic biomarkers to improve the delivery of DBS therapy, and on novel treatments for Musician’s Dystonia and other forms of occupational Dystonia. Dr. Mason is also leading development of the multidisciplinary USC Musician’s Neurology Clinic.

Dr. Mason completed his medical training at Harvard Medical School, Massachusetts General Hospital, Brigham and Women’s Hospital, and UCLA. He undertook a research fellowship with the Howard Hughes Medical Institute and training in Clinical/Translational Research with the UCLA-CTSI and SC-CTSI. He joined the USC faculty in the departments of Neurological Surgery and Neurology in 2021.


  • Protocol for a scoping review of factors associated with disparities in clinical provision of deep brain stimulation BMJ Open. 2024 Mar 21; 14(3):e079601. . View in PubMed
  • Neuromodulation of Eating Disorders: A Review of Underlying Neural Network Activity and Neuromodulatory Treatments Brain Sci. 2024 Feb 22; 14(3). . View in PubMed
  • A review of neurophysiological effects and efficiency of waveform parameters in deep brain stimulation Clin Neurophysiol. 2023 08; 152:93-111. . View in PubMed
  • Racial disparities in access to DBS: results of a real-world US. claims data analysis. Front Neurol. 2023; 14:1233684. . View in PubMed
  • Challenges to the Diagnosis of Functional Neurological Disorder: Feigning, Intentionality, and Responsibility Neuroethics. 2023; 16(1):2. . View in PubMed
  • Neuromodulation of OCD: A review of invasive and non-invasive methods Front Neurol. 2022; 13:909264. . View in PubMed
  • Vim-Thalamic Deep Brain Stimulation for Cervical Dystonia and Upper-Limb Tremor: Quantification by Markerless-3D Kinematics and Accelerometry Tremor Other Hyperkinet Mov (N Y). 2022; 12:5. . View in PubMed
  • Adult onset POLR3A leukodystrophy presenting with parkinsonism treated with pallidal deep brain stimulation Parkinsonism Relat Disord. 2021 04; 85:23-25. . View in PubMed
  • Clinical Reasoning: Moyamoya disease masquerading as acute refractory cerebral vasospasm Neurology. 2018 08 07; 91(6):e594-e598. . View in PubMed
  • Cardiogenic Shock and Respiratory Failure in a Patient With Metastatic Melanoma Receiving Trametinib Therapy Oncologist. 2016 09; 21(9):1136-7. . View in PubMed
  • Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):7291-6. . View in PubMed
  • Dopamine decreases NMDA currents in the oval bed nucleus of the stria terminalis of cocaine self-administering rats Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jun 03; 51:83-8. . View in PubMed
  • D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats J Neurosci. 2013 Jul 17; 33(29):11960-71. . View in PubMed
  • Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization Circulation. 2013 Jul 09; 128(2):101-14. . View in PubMed
  • A switch in the neuromodulatory effects of dopamine in the oval bed nucleus of the stria terminalis associated with cocaine self-administration in rats J Neurosci. 2011 Jun 15; 31(24):8928-35. . View in PubMed
  • Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis J Neurophysiol. 2011 Jan; 105(1):145-53. . View in PubMed
  • Creation of a functional tricuspid valve: novel use of percutaneously implanted valve in right atrial to right ventricular conduit in a patient with tricuspid atresia Int J Cardiol. 2010 Sep 24; 144(1):e8-10. . View in PubMed