Xiaoyue Mona Guo

Assistant Professor of Clinical Obstetrics and Gynecology

Image of Xiaoyue Mona Guo
Is this your profile? Click to edit

Overview

Xiaoyue Mona Guo, MD, is a gynecologic oncologist at Keck Medicine of USC. Dr. Guo uses a comprehensive approach to treat various forms of gynecologic cancer, such as ovarian, uterine and cervical cancers. She specializes in minimally invasive and open surgical techniques for cancer treatment and also delivers chemotherapy. She understands being diagnosed with these types of conditions can be a stressful experience, and her patients can rely on her for support and exceptional care. Dr. Guo prioritizes honest communication and education, and she always takes the time to ensure patients and their loved ones understand their diagnosis and individualized treatment options.

Dr. Guo’s research interests are on strategies to enhance patient-provider interactions. Her award-winning research has also been widely published in peer-reviewed journals. In addition to her clinical and research work, Dr. Guo is committed to educating the next generation of gynecologic surgeons and serves as both the assistant fellowship director of gynecologic oncology and an assistant professor of clinical obstetrics and gynecology at the Keck School of Medicine of USC.

Publications

  • Reply to Correspondence on “Adnexectomy without intra-operative capsule rupture for early ovarian cancer: survival comparison between minimally invasive and open surgery by Matsuo et al” by Ghalleb and Ben Dhiab. Int J Gynecol Cancer. 2026 Aug 11; 104961.. View in PubMed
  • Nonadherence to Cervical Cancer Screening Guidelines in Commercially Insured US Adults, 2013-2021. JAMA Netw Open. 2025 Dec 01; 8(12):e2548512.. View in PubMed
  • Themes, perspectives, and educational quality of content related to #PapSmears on TikTok. Gynecol Oncol Rep. 2025 Oct; 61:101964.. View in PubMed
  • Temporal trends of sentinel lymph node biopsy without lymphadenectomy at cervical cancer surgery. Gynecol Oncol. 2025 05; 196:182-191.. View in PubMed
  • Survival effect of adjuvant therapy for low-risk endometrial cancer with isolated tumor cells. Am J Obstet Gynecol. 2025 Aug; 233(2):e43-e45.. View in PubMed
  • New opportunities for opportunistic salpingectomy: Leveraging non-gynecologic surgeries for ovarian cancer prevention. Gynecol Oncol Rep. 2025 Apr; 58:101720.. View in PubMed
  • Considerations for route of hysterectomy in low-risk cervical cancer. Int J Gynecol Cancer. 2024 09 02; 34(9):1481.. View in PubMed
  • Risks and benefits of sentinel lymph node evaluation in the management of endometrial intraepithelial neoplasia. Expert Rev Anticancer Ther. 2024 Aug; 24(8):745-753.. View in PubMed
  • Correspondence on “Sentinel lymph node assessment in patients with atypical endometrial hyperplasia: a systematic review and meta-analysis” by Vieira-Serna et al. Int J Gynecol Cancer. 2024 04 01; 34(4):654.. View in PubMed
  • Cesarean hysterectomy for placenta accreta spectrum: 3-2-1 approach. Gynecol Oncol Rep. 2024 Jun; 53:101366.. View in PubMed