Keck School Faculty

Xuejuan Jiang

Xuejuan Jiang

Associate Professor of Research Ophthalmology
Director of Biostatistics
HC4 3700 1450 San Pablo Street Health Sciences Campus Los Angeles

University of Southern California: International Student Academic Achievement Award, 2005

University of Science and Technology of China: Honor Graduate, 2002

Refractive Error and Anterior Chamber Depth as Risk Factors in Primary Angle Closure Disease: The Chinese American Eye Study J Glaucoma. 2023 Apr 01; 32(4):257-264. . View in PubMed

Optimal number and orientation of anterior segment OCT images to measure ocular biometric parameters in angle closure eyes: the Chinese American Eye Study Br J Ophthalmol. 2022 Jan 21. . View in PubMed

Ocular Biometric Determinants of Dark-to-Light Change in Angle Width: The Chinese American Eye Study Am J Ophthalmol. 2022 05; 237:183-192. . View in PubMed

Visual Outcomes in Eyes With Neovascular Glaucoma and Anterior Segment Neovascularization Without Glaucoma Am J Ophthalmol. 2022 04; 236:1-11. . View in PubMed

Hemiretinal Asymmetry in Peripapillary Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes Am J Ophthalmol. 2021 10; 230:156-165. . View in PubMed

Retinal Nerve Fiber Layer Thickness in Healthy Eyes of Black, Chinese, and Latino Americans: A Population-Based Multiethnic Study Ophthalmology. 2021 07; 128(7):1005-1015. . View in PubMed

Optical Coherence Tomography Angiography-Derived Flux As a Measure of Physiological Changes in Retinal Capillary Blood Flow Transl Vis Sci Technol. 2021 08 02; 10(9):5. . View in PubMed

Longer Axial Length Potentiates Relationship of Intraocular Pressure and Peripapillary Vessel Density in Glaucoma Patients Invest Ophthalmol Vis Sci. 2021 07 01; 62(9):37. . View in PubMed

Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease Alzheimers Dement (Amst). 2021; 13(1):e12162. . View in PubMed

Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2020 12; 220:19-26. . View in PubMed

A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population Transl Vis Sci Technol. 2020 05; 9(6):25. . View in PubMed

Lower retinal capillary density in minimal cognitive impairment among older Latinx adults Alzheimers Dement (Amst). 2020; 12(1):e12071. . View in PubMed

Association of Parental Myopia With Higher Risk of Myopia Among Multiethnic Children Before School Age JAMA Ophthalmol. 2020 05 01; 138(5):501-509. . View in PubMed

Machine Learning Models for Diagnosing Glaucoma from Retinal Nerve Fiber Layer Thickness Maps Ophthalmol Glaucoma. 2019 Nov - Dec; 2(6):422-428. . View in PubMed

Prevalence, Characteristics, and Risk Factors of Moderate or High Hyperopia among Multiethnic Children 6 to 72 Months of Age: A Pooled Analysis of Individual Participant Data Ophthalmology. 2019 07; 126(7):989-999. . View in PubMed

Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. . View in PubMed

Factors Associated with Prevalent Diabetic Retinopathy in Chinese Americans: The Chinese American Eye Study Ophthalmol Retina. 2018 Feb; 2(2):96-105. . View in PubMed

The African American Eye Disease Study: Design and Methods Ophthalmic Epidemiol. 2018 08; 25(4):306-314. . View in PubMed

Variation in Intraocular Pressure and the Risk of Developing Open-Angle Glaucoma: The Los Angeles Latino Eye Study Am J Ophthalmol. 2018 04; 188:51-59. . View in PubMed

Prevalence and Characteristics of Myopic Degeneration in an Adult Chinese American Population: The Chinese American Eye Study Am J Ophthalmol. 2018 03; 187:34-42. . View in PubMed

Factors Associated with Age-Related Macular Degeneration in Chinese American Adults: The Chinese American Eye Study (CHES) Ophthalmol Retina. 2018 03; 2(3):209-216. . View in PubMed

The "Curse" of the Fellow Eye in Glaucoma JAMA Ophthalmol. 2018 10 01; 136(10):1156-1157. . View in PubMed

Self-reported Use of Eye Care Among Adult Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2017 Apr; 176:183-193. . View in PubMed

Prevalence and Risk Factors for Refractive Error in Adult Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2017 Mar; 175:201-212. . View in PubMed

Use of Structural End Points in Glaucoma: Beyond Visual Field Loss JAMA Ophthalmol. 2017 07 01; 135(7):789-790. . View in PubMed

Visual Impairment in Preschool Children in the United States: Demographic and Geographic Variations From 2015 to 2060 JAMA Ophthalmol. 2017 06 01; 135(6):610-616. . View in PubMed

Ocular Determinants of Refractive Error and Its Age- and Sex-Related Variations in the Chinese American Eye Study JAMA Ophthalmol. 2017 07 01; 135(7):724-732. . View in PubMed

Quantifying Retinal Microvascular Changes in Uveitis Using Spectral-Domain Optical Coherence Tomography Angiography Am J Ophthalmol. 2016 Nov; 171:101-112. . View in PubMed

Prevalence of Diabetic Retinopathy in Adult Chinese American Individuals: The Chinese American Eye Study JAMA Ophthalmol. 2016 May 01; 134(5):563-569. . View in PubMed

The Role of Contextual Factors in Racial/Ethnic Disparities in Eye Care Use JAMA Ophthalmol. 2016 10 01; 134(10):1167-1168. . View in PubMed

Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6313-6319. . View in PubMed

Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program Cancer. 2013 Feb 15; 119(4):756-65. . View in PubMed

Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry PLoS One. 2013; 8(4):e60464. . View in PubMed

Baseline risk factors that predict the development of open-angle glaucoma in a population: the Los Angeles Latino Eye Study Ophthalmology. 2012 Nov; 119(11):2245-53. . View in PubMed

Diabetes and risk of esophageal and gastric adenocarcinomas Int J Cancer. 2012 Sep 15; 131(6):1417-22. . View in PubMed

Cigarette smoking and subtypes of bladder cancer Int J Cancer. 2012 Feb 15; 130(4):896-901. . View in PubMed

Family history and breast cancer hormone receptor status in a Spanish cohort PLoS One. 2012; 7(1):e29459. . View in PubMed

Association of the calcyon neuron-specific vesicular protein gene (CALY) with adolescent smoking initiation in China and California Am J Epidemiol. 2011 May 01; 173(9):1039-48. . View in PubMed

Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study Carcinogenesis. 2011 Feb; 32(2):197-202. . View in PubMed

Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control study Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3150-6. . View in PubMed

Hypertension, diuretics and antihypertensives in relation to bladder cancer Carcinogenesis. 2010 Nov; 31(11):1964-71. . View in PubMed

Urinary tract infections and reduced risk of bladder cancer in Los Angeles Br J Cancer. 2009 Mar 10; 100(5):834-9. . View in PubMed

Water intake and bladder cancer risk in Los Angeles County Int J Cancer. 2008 Oct 01; 123(7):1649-56. . View in PubMed

Alcohol consumption and risk of bladder cancer in Los Angeles County Int J Cancer. 2007 Aug 15; 121(4):839-45. . View in PubMed

Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County Cancer Res. 2007 Aug 01; 67(15):7540-5. . View in PubMed

Lipid peroxidation and the protective effect of physical exercise on breast cancer Med Hypotheses. 2007; 68(5):1138-43. . View in PubMed

Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis Breast Cancer Res. 2007; 9(1):201. . View in PubMed

Xuejuan Jiang received a BS with Honors in Molecular and Cellular Biology from University of Science and Technology of China in 2002. Subsequently, she joined the graduate program in Biomedical and Biological Sciences (PIBBS) at University of Southern California (USC), and received a M.S. in Applied Biostatistics and Epidemiology and a PhD in Epidemiology. At USC, Dr. Jiang investigated how smoking affects bladder cancer risk. Her research provided strong evidence supporting that 1) second-hand smoke can increase bladder cancer risk in female lifelong nonsmokers, 2) genetic variations associated with nicotine dependence and smoking behavior can also affect bladder cancer risk, and 3) use of non-steroidal anti-inflammatory may attenuate the carcinogenic effect of cigarette smoking on the bladder. In addition, she found that factors associated with prolonged exposure to carcinogens in the urine, e.g. infrequent drinking and urination, may increase bladder cancer risk. After earning her doctorate, Dr. Jiang became a postdoctoral research associate at USC, where she focused on using pathway-based systemic approaches to investigate genetic components of adolescent alcohol drinking, bladder cancer, and colorectal cancer, and developing noninvasive biomarkers of oxidative stress. Dr. Jiang joined USC’s Department of Ophthalmology as an Assistant Professor of Research in 2011.

As an experienced epidemiologist, Xuejuan Jiang, PhD, has expertise in designing, managing and analyzing epidemiological studies to evaluate the impact of different environmental and genetic risk factors, on various cancers, adolescent smoking/drinking behaviors, and ocular disorders. In particular, Dr. Jiang’s research on ocular disease focuses on etiologies of glaucoma, diabetic retinopathy, and refractive errors, especially myopia, identifying early indicators of disease development and progression, and developing possible prevention, intervention and treatments.

Dr. Jiang is currently leading the international effort in consolidating all existing population-based studies of eye diseases among preschool children, to create the largest repository of population-based survey data on vision health among preschool children. Results from this project will improve our understanding of the risk factors for the most common pediatric vision disorders among preschool children, and help inform and develop evidence-based guidelines for population screening and clinical management.
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