Faculty

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Myles Gordon Cockburn, PhD
Research Professor of Preventive Medicine (Part-Time)
Preventive Medicine
SSB 318A 2001 N. Soto Street Health Sciences Campus Los Angeles
+1 323 865 0322

Overview

Myles Cockburn is Associate Professor in Preventive Medicine, focusing on cancer etiology and prevention. A native of New Zealand, he came to USC to study melanoma risk factors and to design methods for improved primary prevention and screening. His current research focuses on improving SunSmart attitudes and behaviors in school children throughout Los Angeles, developing skin self examination methods for effective skin cancer screening, and working with clinical dermatologists and oncologists to better understand the complex role of UV in melanogenesis. Incorporating his background in GIS and spatial sciences, he has worked extensively on elucidating the role of pesticide exposures in hormone-related cancers and Parkinson’s Disease with collaborators from UCLA and elsewhere in California. In his role in the Los Angeles Cancer Surveillance Program he is responsible for the development and dissemination of novel methods for improving cancer control, particularly in diverse and underserved populations. Dr. Cockburn mentors a number of PhD students who are trained in all aspects of epidemiologic investigation while participating in, and often taking a leading role in, his ongoing research studies. Dr. Cockburn is a member of the Norris Comprehensive Cancer Center, the Southern California Environmental Health Sciences Center, and USC’s Spatial Sciences Institute.

Publications

. Early estimates of cancer incidence for 2015: Expanding to include estimates for white and black races Cancer. 2018 May 15; 124(10):2192-2204. View in: PubMed

. NFE2L2, PPARGC1a, and pesticides and Parkinson's disease risk and progression Mech Ageing Dev. 2018 Apr 06; 173:1-8. View in: PubMed

. Impact of individual and neighborhood factors on disparities in prostate cancer survival Cancer Epidemiol. 2018 Apr; 53:1-11. View in: PubMed

. Prevalence of Tanning Addiction and Behavioral Health Conditions among Ethnically and Racially Diverse Adolescents J Invest Dermatol. 2018 Feb 23. View in: PubMed

. Cognitive decline, mortality, and organophosphorus exposure in aging Mexican Americans Environ Res. 2018 01; 160:132-139. View in: PubMed

. Prevalence of sun protection behaviors in Hispanic youth residing in a high ultraviolet light environment Pediatr Dermatol. 2018 Jan; 35(1):e52-e54. View in: PubMed

. Characterizing the neighborhood obesogenic environment in the Multiethnic Cohort: a multi-level infrastructure for cancer health disparities research Cancer Causes Control. 2018 Jan; 29(1):167-183. View in: PubMed

. Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California Cancer Causes Control. 2017 Oct; 28(10):1117-1123. View in: PubMed

. Early estimates of SEER cancer incidence, 2014 Cancer. 2017 Jul 01; 123(13):2524-2534. View in: PubMed

. The role of spatially-derived access-to-care characteristics in melanoma prevention and control in Los Angeles county Health Place. 2017 May; 45:160-172. View in: PubMed

. Correlates of sun protection behaviors among Hispanic children residing in a high UVR environment Photodermatol Photoimmunol Photomed. 2017 Mar; 33(2):75-83. View in: PubMed

. Trends in childhood leukemia incidence over two decades from 1992 to 2013 Int J Cancer. 2017 Mar 01; 140(5):1000-1008. View in: PubMed

. Risk of malignant childhood germ cell tumors in relation to demographic, gestational, and perinatal characteristics Cancer Epidemiol. 2017 Feb; 46:42-49. View in: PubMed

. Mucosal melanomas in the racially diverse population of California J Am Acad Dermatol. 2017 Feb; 76(2):250-257. View in: PubMed

. Evaluating the use of friend or family controls in epidemiologic case-control studies Cancer Epidemiol. 2017 Feb; 46:9-13. View in: PubMed

. Exposure to ambient dichloromethane in pregnancy and infancy from industrial sources and childhood cancers in California Int J Hyg Environ Health. 2017 10; 220(7):1133-1140. View in: PubMed

. Organophosphate pesticides and PON1 L55M in Parkinson's disease progression Environ Int. 2017 10; 107:75-81. View in: PubMed

. Racial/Ethnic Differences in the Impact of Neighborhood Social and Built Environment on Breast Cancer Risk: The Neighborhoods and Breast Cancer Study Cancer Epidemiol Biomarkers Prev. 2017 04; 26(4):541-552. View in: PubMed

. Maternal Preeclampsia and Odds of Childhood Cancers in Offspring: A California Statewide Case-Control Study Paediatr Perinat Epidemiol. 2017 03; 31(2):157-164. View in: PubMed

. Particulate matter air pollution and liver cancer survival Int J Cancer. 2017 08 15; 141(4):744-749. View in: PubMed

. Interobserver reliability of teledermatology across all Fitzpatrick skin types J Telemed Telecare. 2017 Jan; 23(1):68-73. View in: PubMed

. Teledermatology as a tool to improve access to care for medically underserved populations: A retrospective descriptive study J Am Acad Dermatol. 2016 Dec; 75(6):1259-1261. View in: PubMed

. Low birth weight and air pollution in California: Which sources and components drive the risk? Environ Int. 2016 Jul-Aug; 92-93:471-7. View in: PubMed

. Risk of Childhood Cancer by Maternal Birthplace: A Test of the Hispanic Paradox JAMA Pediatr. 2016 Jun 01; 170(6):585-92. View in: PubMed

. Tanning bed use and melanoma: Establishing risk and improving prevention interventions Prev Med Rep. 2016 Jun; 3:139-44. View in: PubMed

. Preliminary estimates of SEER cancer incidence for 2013 Cancer. 2016 May 15; 122(10):1579-87. View in: PubMed

. Air pollution affects lung cancer survival Thorax. 2016 10; 71(10):891-8. View in: PubMed

. Maternal pre-pregnancy and gestational diabetes, obesity, gestational weight gain, and risk of cancer in young children: a population-based study in California Cancer Causes Control. 2016 10; 27(10):1273-85. View in: PubMed

. A Statewide Nested Case-Control Study of Preterm Birth and Air Pollution by Source and Composition: California, 2001-2008 Environ Health Perspect. 2016 09; 124(9):1479-86. View in: PubMed

. Correlation of Insurance, Race, and Ethnicity with Pathologic Risk in a Controlled Retinoblastoma Cohort: A Children's Oncology Group Study Ophthalmology. 2016 08; 123(8):1817-1823. View in: PubMed

. In Utero and Early-Life Exposure to Ambient Air Toxics and Childhood Brain Tumors: A Population-Based Case-Control Study in California, USA Environ Health Perspect. 2016 07; 124(7):1093-9. View in: PubMed

. Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson's Disease, California (USA) Environ Health Perspect. 2016 05; 124(5):570-7. View in: PubMed

. Smoking in pregnancy and risk of cancer among young children: A population-based study Int J Cancer. 2016 08 01; 139(3):613-6. View in: PubMed

. Current Data on Risk Factor Estimates Does Not Explain the Difference in Rates of Melanoma between Hispanics and Non-Hispanic Whites J Skin Cancer. 2016; 2016:2105250. View in: PubMed

. Childhood leukaemia and distance from power lines in California: a population-based case-control study Br J Cancer. 2016 06 28; 115(1):122-8. View in: PubMed

. Patterns of sun protective behaviors among Hispanic children in a skin cancer prevention intervention Prev Med. 2015 Dec; 81:303-8. View in: PubMed

. Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease Environ Res. 2015 Nov; 143(Pt A):98-106. View in: PubMed

. Modeling spatial effects of PM(25) on term low birth weight in Los Angeles County. Environ Res. 2015 Oct; 142:354-64. View in: PubMed

. Race/ethnicity and the risk of childhood leukaemia: a case-control study in California J Epidemiol Community Health. 2015 Aug; 69(8):795-802. View in: PubMed

. Prevalence and predictors of recent skin examination in a population-based twin cohort Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1190-8. View in: PubMed

. Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure J Neurol Sci. 2015 May 15; 352(1-2):88-93. View in: PubMed

. Rising rates of acute lymphoblastic leukemia in Hispanic children: trends in incidence from 1992 to 2011 Blood. 2015 May 07; 125(19):3033-4. View in: PubMed

. Retinoblastoma and ambient exposure to air toxics in the perinatal period J Expo Sci Environ Epidemiol. 2015 Mar-Apr; 25(2):182-6. View in: PubMed

. Epidemiologic study of residential proximity to transmission lines and childhood cancer in California: description of design, epidemiologic methods and study population J Expo Sci Environ Epidemiol. 2015 Jan; 25(1):45-52. View in: PubMed

. In utero exposure to toxic air pollutants and risk of childhood autism Epidemiology. 2014 Nov; 25(6):851-8. View in: PubMed

. Sources and contents of air pollution affecting term low birth weight in Los Angeles County, California, 2001-2008 Environ Res. 2014 Oct; 134:488-95. View in: PubMed

. The effect of neighborhood and individual characteristics on pediatric critical illness J Community Health. 2014 Aug; 39(4):753-9. View in: PubMed

. Exposure to infections and risk of leukemia in young children Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1195-203. View in: PubMed

. Risk of leukemia in relation to exposure to ambient air toxics in pregnancy and early childhood Int J Hyg Environ Health. 2014 Jul; 217(6):662-8. View in: PubMed

. Prenatal exposure to air toxics and risk of Wilms' tumor in 0- to 5-year-old children J Occup Environ Med. 2014 Jun; 56(6):573-8. View in: PubMed

. Impact of neighborhood and individual socioeconomic status on survival after breast cancer varies by race/ethnicity: the Neighborhood and Breast Cancer Study Cancer Epidemiol Biomarkers Prev. 2014 May; 23(5):793-811. View in: PubMed

. The association between ambient exposure to organophosphates and Parkinson's disease risk Occup Environ Med. 2014 Apr; 71(4):275-81. View in: PubMed

. Molecular characteristics of diffuse large B-cell lymphoma in human immunodeficiency virus-infected and -uninfected patients in the pre-highly active antiretroviral therapy and pre-rituximab era Leuk Lymphoma. 2014 Mar; 55(3):551-7. View in: PubMed

. Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease Neurology. 2014 Feb 04; 82(5):419-26. View in: PubMed

. Birth characteristics and risk of lymphoma in young children Cancer Epidemiol. 2014 Feb; 38(1):48-55. View in: PubMed

. Epstein-Barr virus patterns in US Burkitt lymphoma tumors from the SEER residual tissue repository during 1979-2009 APMIS. 2014 Jan; 122(1):5-15. View in: PubMed

. Trends in childhood brain tumor incidence, 1973-2009 J Neurooncol. 2013 Nov; 115(2):153-60. View in: PubMed

. Childhood cancer and traffic-related air pollution exposure in pregnancy and early life Environ Health Perspect. 2013 Nov-Dec; 121(11-12):1385-91. View in: PubMed

. An exploratory study of ambient air toxics exposure in pregnancy and the risk of neuroblastoma in offspring Environ Res. 2013 Nov; 127:1-6. View in: PubMed

. Prenatal exposure to traffic-related air pollution and risk of early childhood cancers Am J Epidemiol. 2013 Oct 15; 178(8):1233-9. View in: PubMed

. Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson? s disease. Environ Res. 2013 Oct; 126:1-8. View in: PubMed

. Alterations of DNA methylome in human bladder cancer Epigenetics. 2013 Oct; 8(10):1013-22. View in: PubMed

. Childhood infections and adult height in monozygotic twin pairs Am J Epidemiol. 2013 Aug 15; 178(4):551-8. View in: PubMed

. Case-control study of birth characteristics and the risk of hepatoblastoma Cancer Epidemiol. 2013 Aug; 37(4):390-5. View in: PubMed

. Solar UV radiation and cancer in young children Cancer Epidemiol Biomarkers Prev. 2013 Jun; 22(6):1118-28. View in: PubMed

. The joint effects of census tract poverty and geographic access on late-stage breast cancer diagnosis in 10 US States Health Place. 2013 May; 21:110-21. View in: PubMed

. Ambient air pollution and autism in Los Angeles county, California Environ Health Perspect. 2013 Mar; 121(3):380-6. View in: PubMed

. The USC Adult Twin Cohorts: International Twin Study and California Twin Program Twin Res Hum Genet. 2013 Feb; 16(1):366-70. View in: PubMed

. Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease Proc Natl Acad Sci U S A. 2013 Jan 08; 110(2):636-41. View in: PubMed

. Comorbidities and endometrial cancer survival in Hispanics and non-Hispanic whites Cancer Causes Control. 2013 Jan; 24(1):61-9. View in: PubMed

. Epidemiology of rhabdoid tumors of early childhood Pediatr Blood Cancer. 2013 Jan; 60(1):77-81. View in: PubMed

. Treatment and Mortality in Men with Localized Prostate Cancer: A Population-Based Study in California Open Prost Cancer J. 2013; 6:1-9. View in: PubMed

. A simple intervention to reinforce awareness of tanning bed use and skin cancer in non-medical skin care professionals in Southern California Int J Dermatol. 2012 Nov; 51(11):1307-12. View in: PubMed

. Perinatal characteristics and retinoblastoma Cancer Causes Control. 2012 Sep; 23(9):1567-75. View in: PubMed

. Assessing the influence of traffic-related air pollution on risk of term low birth weight on the basis of land-use-based regression models and measures of air toxics Am J Epidemiol. 2012 Jun 15; 175(12):1262-74. View in: PubMed

. The effect of administrative boundaries and geocoding error on cancer rates in California Spat Spatiotemporal Epidemiol. 2012 Apr; 3(1):39-54. View in: PubMed

. e-Health Tools for Targeting and Improving Melanoma Screening: A Review J Skin Cancer. 2012; 2012:437502. View in: PubMed

. Traffic-related air toxics and term low birth weight in Los Angeles County, California Environ Health Perspect. 2012 Jan; 120(1):132-8. View in: PubMed

. Breast cancer stage at diagnosis: is travel time important? J Community Health. 2011 Dec; 36(6):933-42. View in: PubMed

. Association between cutaneous melanoma incidence rates among white US residents and county-level estimates of solar ultraviolet exposure J Am Acad Dermatol. 2011 Nov; 65(5 Suppl 1):S50-7. View in: PubMed

. Melanoma surveillance in the United States: overview of methods J Am Acad Dermatol. 2011 Nov; 65(5 Suppl 1):S6-16. View in: PubMed

. Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California Environ Health. 2011 Oct 07; 10:89. View in: PubMed

. Challenges in identifying Native Hawaiians and Pacific Islanders in population-based cancer registries in the US. J Immigr Minor Health. 2011 Oct; 13(5):860-6. View in: PubMed

. Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight FASEB J. 2011 Sep; 25(9):3079-91. View in: PubMed

. Adulthood residential ultraviolet radiation, sun sensitivity, dietary vitamin D, and risk of lymphoid malignancies in the California Teachers Study Blood. 2011 Aug 11; 118(6):1591-9. View in: PubMed

. Geographic proximity to treatment for early stage breast cancer and likelihood of mastectomy Breast. 2011 Aug; 20(4):324-8. View in: PubMed

. Increases in melanoma among adolescent girls and young women in California: trends by socioeconomic status and UV radiation exposure Arch Dermatol. 2011 Jul; 147(7):783-9. View in: PubMed

. Preliminary evidence for mediation of the association between acculturation and sun-safe behaviors Arch Dermatol. 2011 Jul; 147(7):814-9. View in: PubMed

. Parkinson's disease risk from ambient exposure to pesticides Eur J Epidemiol. 2011 Jul; 26(7):547-55. View in: PubMed

. Cutaneous melanoma and other skin cancer screening among Hispanics in the United States: a review of the evidence, disparities, and need for expanding the intervention and research agendas Arch Dermatol. 2011 Jun; 147(6):743-5. View in: PubMed

. Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California Am J Epidemiol. 2011 Jun 01; 173(11):1280-8. View in: PubMed

. The expanding melanoma burden in California hispanics: Importance of socioeconomic distribution, histologic subtype, and anatomic location Cancer. 2011 Jan 01; 117(1):152-61. View in: PubMed

. Interaction of area-level socioeconomic status and UV radiation on melanoma occurrence in California Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2727-33. View in: PubMed

. Moderated mediation regarding the sun-safe behaviors of US. Latinos: advancing the theory and evidence for acculturation-focused research and interventions. J Immigr Minor Health. 2010 Oct; 12(5):691-8. View in: PubMed

. Racial and social class gradients in life expectancy in contemporary California Soc Sci Med. 2010 May; 70(9):1373-80. View in: PubMed

. Hidden breast cancer disparities in Asian women: disaggregating incidence rates by ethnicity and migrant status Am J Public Health. 2010 Apr 01; 100 Suppl 1:S125-31. View in: PubMed

. Efficacy of skin self-examination for the early detection of melanoma Int J Dermatol. 2010 Feb; 49(2):126-34. View in: PubMed

. a-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease Neuroepidemiology. 2010; 35(3):191-5. View in: PubMed

. Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease Epidemiology. 2010 Jan; 21(1):87-94. View in: PubMed

. Well-water consumption and Parkinson's disease in rural California Environ Health Perspect. 2009 Dec; 117(12):1912-8. View in: PubMed

. Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California Cancer Causes Control. 2009 Oct; 20(8):1431-40. View in: PubMed

. Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo J Am Coll Cardiol. 2009 Sep 01; 54(10):944-54. View in: PubMed

. Increasing burden of melanoma in the United States J Invest Dermatol. 2009 Jul; 129(7):1666-74. View in: PubMed

. Dopamine transporter genetic variants and pesticides in Parkinson's disease Environ Health Perspect. 2009 Jun; 117(6):964-9. View in: PubMed

. Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California Am J Epidemiol. 2009 Apr 15; 169(8):919-26. View in: PubMed

. Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray Cancer Res. 2009 Apr 01; 69(7):2950-5. View in: PubMed

. Acculturation and sun-safe behaviors among US Latinos: findings from the 2005 Health Information National Trends Survey Am J Public Health. 2009 Apr; 99(4):734-41. View in: PubMed

. The relative importance of genetics and environment on mammographic density Cancer Epidemiol Biomarkers Prev. 2009 Jan; 18(1):102-12. View in: PubMed

. Melanoma underreporting: why does it happen, how big is the problem, and how do we fix it? J Am Acad Dermatol. 2008 Dec; 59(6):1081-5. View in: PubMed

. An effective and efficient approach for manually improving geocoded data Int J Health Geogr. 2008 Nov 26; 7:60. View in: PubMed

. Measurement of ultraviolet exposure in epidemiological studies of skin and skin cancers Photochem Photobiol. 2008 Nov-Dec; 84(6):1462-72. View in: PubMed

. Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion J Am Coll Cardiol. 2008 Oct 28; 52(18):1468-81. View in: PubMed

. Prevalence and predictors of skin self-examination: prospects for melanoma prevention and early detection Int J Dermatol. 2008 Oct; 47(10):993-1003. View in: PubMed

. Heritability and genome-wide linkage in US and australian twins identify novel genomic regions controlling chromogranin a: implications for secretion and blood pressure Circulation. 2008 Jul 15; 118(3):247-57. View in: PubMed

. Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma Blood. 2008 Apr 01; 111(7):3377-82. View in: PubMed

. Use of an electrostatic dust cloth for self-administered home allergen collection Twin Res Hum Genet. 2008 Apr; 11(2):150-5. View in: PubMed

. Population-based linkage of AIDS and cancer registries: importance of linkage algorithm Am J Prev Med. 2007 Aug; 33(2):134-6. View in: PubMed

. Heredity of endothelin secretion: human twin studies reveal the influence of polymorphism at the chromogranin A locus, a novel determinant of endothelial function Circulation. 2007 May 01; 115(17):2282-91. View in: PubMed

. The simultaneous assessment of constitutional, behavioral, and environmental factors in the development of large nevi Cancer Epidemiol Biomarkers Prev. 2007 Feb; 16(2):200-6. View in: PubMed

. Twins as willing research participants: successes from studies nested within the California Twin Program Twin Res Hum Genet. 2006 Dec; 9(6):927-32. View in: PubMed

. The objective assessment of lifetime cumulative ultraviolet exposure for determining melanoma risk J Photochem Photobiol B. 2006 Dec 01; 85(3):198-204. View in: PubMed

. Gender differences in determinants of smoking initiation and persistence in California twins Cancer Epidemiol Biomarkers Prev. 2006 Jun; 15(6):1189-97. View in: PubMed

. Developing epidemic of melanoma in the Hispanic population of California Cancer. 2006 Mar 01; 106(5):1162-8. View in: PubMed

. Control selection and pesticide exposure assessment via GIS in prostate cancer studies Am J Prev Med. 2006 Feb; 30(2 Suppl):S109-16. View in: PubMed

. A population-based description of glioblastoma multiforme in Los Angeles County, 1974-1999 Cancer. 2005 Dec 15; 104(12):2798-806. View in: PubMed

. Etiologic clues from the similarity of histology-specific trends in esophageal and lung cancers Cancer Causes Control. 2005 Nov; 16(9):1065-74. View in: PubMed

. Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins Physiol Genomics. 2004 Nov 17; 19(3):277-91. View in: PubMed

. Th1 and Th2 cytokines and IgE levels in identical twins with varying levels of cigarette consumption J Clin Immunol. 2004 Nov; 24(6):617-22. View in: PubMed

. IL-6 levels and genotype are associated with risk of young adult Hodgkin lymphoma Blood. 2004 Apr 15; 103(8):3216-21. View in: PubMed

. An estimate of physical activity prevalence in a large population-based cohort Med Sci Sports Exerc. 2004 Feb; 36(2):253-60. View in: PubMed

. Role of Helicobacter pylori CagA+ strains and risk of adenocarcinoma of the stomach and esophagus Int J Cancer. 2003 Mar 01; 103(6):815-21. View in: PubMed

. The occurrence of chronic disease and other conditions in a large population-based cohort of native Californian twins Twin Res. 2002 Oct; 5(5):460-7. View in: PubMed

. Determinants of melanoma in a case-control study of twins (United States) Cancer Causes Control. 2001 Sep; 12(7):615-25. View in: PubMed

. Development and representativeness of a large population-based cohort of native Californian twins Twin Res. 2001 Aug; 4(4):242-50. View in: PubMed

. Recall bias in self-reported melanoma risk factors Am J Epidemiol. 2001 May 15; 153(10):1021-6. View in: PubMed

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