Robert Alan Kloner, MD, PhD

Professor of Medicine (Clinical Scholar)

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Awards

Consumer’s Research Council of America: Listed in Guide to America’s Top Cardiologists, 2007
Good Samaritan Hospital: Physician Leadership Award, 2003
Institute for Scientific Information: Identified as one of the world’s most highly cited authors, 2002
American Heart Association: Inaugural Fellow of the Council on Basic Cardiovascular Sciences, 2001
United States Israel Binational Science Foundation: The Henry N. Neufeld Memorial Award, 1996
NIH: Cardiovascular Study Section A, 1995-1998
American Heart Association: Continuing Service Award, 1991
American Society for Clinical Investigation: Elected Member, 1990
82nd Annual Scientific Assembly of the Southern Medical Association: Scientific Exhibit Achievement Award, 1988
American College of Physicians: Research Prize, 1988
American Heart Association: Recipient of the Established Investigatorship Award, 1981-1986
American Society of Clinical Pathologists: Sheard-Sanford Award for Meritorius Original Student Research in Pathology During Medical School, 1976
Merck: Award for Outstanding Achievement in the Study of Medicine, 1975
Alpha Omega Alpha: Member, 1973

Publications

Assessment of Myocardial Injury Size Metrics Using Carotid Pressure Waveform: Proof-of-Concept in Coronary Occlusion/Reperfusion Rat Model. FASEB J. 2025 Sep 15; 39(17):e71029.. View in PubMed
Effects of Intracoronary SuperSaturated Oxygen Therapy on Myocardial Blood Flow, Microvascular Obstruction, and Myocardial Salvage in ST-Segment-Elevation Myocardial Infarction in Swine Ischemia/Reperfusion Model. J Am Heart Assoc. 2025 Aug 05; 14(15):e038891.. View in PubMed
Low HDL-The Challenge. Clin Med Res. 2025 08; 23(2):60-66.. View in PubMed
Coronary Artery Bypass Grafting Is Rarely Done in the Acute Care of ST-elevation Myocardial Infarction Patients Treated by Emergency Medical Services. West J Emerg Med. 2025 May 20; 26(3):729-736.. View in PubMed
Coronary Artery Calcium Scoring Improves Allocation of the GLP-1 Receptor Agonist Semaglutide. JACC Cardiovasc Imaging. 2025 Apr; 18(4):462-464.. View in PubMed
Empagliflozin demonstrates neuroprotective and cardioprotective effects by reducing ischemia/reperfusion damage in rat models of ischemic stroke and myocardial infarction. Sci Rep. 2025 Mar 15; 15(1):8986.. View in PubMed
Reperfused Myocardial Infarction: The Road to CCS Classification of Acute MI and Beyond. JACC Adv. 2025 Feb; 4(2):101528.. View in PubMed
A Review of Cardiovascular Effects of Marijuana Use. J Cardiopulm Rehabil Prev. 2025 01 01; 45(1):2-7.. View in PubMed
Inflammatory response to chronic nicotine-containing electronic cigarette exposure in a rat model of myocardial infarction. Tob Induc Dis. 2025; 23.. View in PubMed
Impact of electronic cigarette vaping on the cardiovascular function in young and old rats. Sci Rep. 2024 12 06; 14(1):30420.. View in PubMed
Androgen Society Position Paper on Cardiovascular Risk With Testosterone Therapy. Mayo Clin Proc. 2024 Nov; 99(11):1785-1801.. View in PubMed
Proceedings of PRINCETON IV: PDE5 inhibitors and cardiac health symposium. Sex Med Rev. 2024 Sep 25; 12(4):681-709.. View in PubMed
Adverse Cardiovascular Effects of Nicotine Delivered by Chronic Electronic Cigarettes or Standard Cigarettes Captured by Cardiovascular Intrinsic Frequencies. J Am Heart Assoc. 2024 Sep 17; 13(18):e035462.. View in PubMed
Higher sodium in older individuals or after stroke/reperfusion, but not in migraine or Alzheimer’s disease – a study in different preclinical models. Sci Rep. 2024 09 16; 14(1):21636.. View in PubMed
The Princeton IV Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease. Mayo Clin Proc. 2024 Sep; 99(9):1500-1517.. View in PubMed
Disrupted brain functional connectivity as early signature in cognitively healthy individuals with pathological CSF amyloid/tau. Commun Biol. 2024 08 23; 7(1):1037.. View in PubMed
An Urgent Call for Studies That Address the Cardiovascular Consequences of Legalization of Marijuana. Cardiol Res. 2024 Apr; 15(2):86-89.. View in PubMed
Impact of symptom-to-reperfusion-time on transmural infarct extent and left ventricular strain in patients with ST-segment elevation myocardial infarction: a 3D view on the wavefront phenomenon. Eur Heart J Cardiovasc Imaging. 2024 Feb 22; 25(3):347-355.. View in PubMed
Association of the COVID-19 Pandemic on Treatment Times for ST-Elevation Myocardial Infarction: Observations from the Los Angeles County Regional System. Am J Cardiol. 2024 02 15; 213:93-98.. View in PubMed
The association of tadalafil exposure with lower rates of major adverse cardiovascular events and mortality in a general population of men with erectile dysfunction. Clin Cardiol. 2024 Feb; 47(2):e24234.. View in PubMed
Effects of Electronic Cigarette Vaping on Cardiac and Vascular Function, and Post-myocardial Infarction Remodeling in Rats. Cardiovasc Toxicol. 2024 Feb; 24(2):199-208.. View in PubMed
Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health. J Sex Med. 2024 01 30; 21(2):90-116.. View in PubMed
Choriocapillaris and Retinal Vascular Alterations in Presymptomatic Alzheimer’s Disease. Invest Ophthalmol Vis Sci. 2024 Jan 02; 65(1):47.. View in PubMed
Flavoring Agents in E-cigarette Liquids: A Comprehensive Analysis of Multiple Health Risks. Cureus. 2023 Nov; 15(11):e48995.. View in PubMed
Instantaneous detection of acute myocardial infarction and ischaemia from a single carotid pressure waveform in rats. Eur Heart J Open. 2023 Sep; 3(5):oead099.. View in PubMed
Cardiac Effects of Phosphodiesterase-5 Inhibitors: Efficacy and Safety. Cardiovasc Drugs Ther. 2023 08; 37(4):793-806.. View in PubMed
Invasive versus Conservative Management in Coronary Artery Disease. Clin Med Res. 2023 06; 21(2):95-104.. View in PubMed
Effect of phosphodiesterase type 5 inhibitors on major adverse cardiovascular events and overall mortality in a large nationwide cohort of men with erectile dysfunction and cardiovascular risk factors: A retrospective, observational study based on healthcare claims and national death index data. J Sex Med. 2023 01 14; 20(1):38-48.. View in PubMed
Effects of Electronic Cigarette Exposure on Myocardial Infarction and No-Reflow, and Cardiac Function in a Rat Model. J Cardiovasc Pharmacol Ther. 2023 Jan-Dec; 28:10742484231155992.. View in PubMed
The connection between heart rate variability (HRV), neurological health, and cognition: A literature review. Front Neurosci. 2023; 17:1055445.. View in PubMed
Marijuana and electronic cigarettes on cardiac arrhythmias. Heart Rhythm. 2023 01; 20(1):87-88.. View in PubMed
The Correlation between COVID-19 Hospitalizations and Emergency Medical Services Responses for Time-Sensitive Emergencies during the COVID-19 Pandemic. Prehosp Emerg Care. 2023; 27(3):321-327.. View in PubMed
Resting heart rate (variability) and cognition relationships reveal cognitively healthy individuals with pathological amyloid/tau ratio. Front Epidemiol. 2023; 3.. View in PubMed
One Acute Exposure to E-Cigarette Smoke Using Various Heating Elements and Power Levels Induces Pulmonary Inflammation. Cardiol Res. 2022 Dec; 13(6):323-332.. View in PubMed
Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model. Cardiovasc Drugs Ther. 2022 04; 36(2):217-227.. View in PubMed
Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction. Sci Rep. 2022 03 22; 12(1):4922.. View in PubMed
Analysis of integrated clinical safety data of tadalafil in patients receiving concomitant antihypertensive medications. J Clin Hypertens (Greenwich). 2022 02; 24(2):167-178.. View in PubMed
Update on Cardioprotective Strategies for STEMI: Focus on Supersaturated Oxygen Delivery. JACC Basic Transl Sci. 2021 Dec; 6(12):1021-1033.. View in PubMed
Task switching reveals abnormal brain-heart electrophysiological signatures in cognitively healthy individuals with abnormal CSF amyloid/tau, a pilot study. Int J Psychophysiol. 2021 12; 170:102-111.. View in PubMed
Scalability of cardiovascular intrinsic frequencies: Validations in preclinical models and non-invasive clinical studies. Life Sci. 2021 Nov 01; 284:119880.. View in PubMed
Treating Acute Myocardial Infarctions With Anti-Inflammatory Agents. J Cardiovasc Pharmacol Ther. 2021 11; 26(6):736-738.. View in PubMed
Post-Acute Sequelae of SARS-COVID-2 Syndrome: Just the Beginning. Cardiol Res. 2021 Oct; 12(5):279-285.. View in PubMed
Cardiac MRI to Visualize Myocardial Damage after ST-Segment Elevation Myocardial Infarction: A Review of Its Histologic Validation. Radiology. 2021 10; 301(1):4-18.. View in PubMed
Emergency Medical Services Responses to Out-of-Hospital Cardiac Arrest and Suspected ST-Segment-Elevation Myocardial Infarction During the COVID-19 Pandemic in Los Angeles County. J Am Heart Assoc. 2021 06 15; 10(12):e019635.. View in PubMed
Cardiovascular Health and Disease in the Context of COVID-19. Cardiol Res. 2021 Apr; 12(2):67-79.. View in PubMed
Viral myocarditis: 1917-2020: From the Influenza A to the COVID-19 pandemics. Trends Cardiovasc Med. 2021 04; 31(3):163-169.. View in PubMed
E-Cigarettes and Cardiopulmonary Health. Function (Oxf). 2021; 2(2):zqab004.. View in PubMed
Therapeutic Hypothermia Improves Long-Term Survival and Blunts Inflammation in Rats During Resuscitation of Hemorrhagic Shock. Ther Hypothermia Temp Manag. 2020 Dec; 10(4):237-243.. View in PubMed
Acute administration of nicotine induces transient elevation of blood pressure and increases myocardial infarct size in rats. Heliyon. 2020 Nov; 6(11):e05450.. View in PubMed
E-cigarette or Vaping Product Use-Associated Lung Injury Produced in an Animal Model From Electronic Cigarette Vapor Exposure Without Tetrahydrocannabinol or Vitamin E Oil. J Am Heart Assoc. 2020 09 15; 9(18):e017368.. View in PubMed
Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association. Circulation. 2020 09 08; 142(10):e131-e152.. View in PubMed
Different Effects of Volatile and Nonvolatile Anesthetic Agents on Long-Term Survival in an Experimental Model of Hemorrhagic Shock. J Cardiovasc Pharmacol Ther. 2020 07; 25(4):346-353.. View in PubMed
Editorial commentary: Continuing concerns about the cardiovascular safety of marijuana. Trends Cardiovasc Med. 2020 07; 30(5):308-309.. View in PubMed
Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction. Cardiovasc Res. 2020 03 01; 116(4):787-805.. View in PubMed
Remote Ischemic Conditioning in Acute Myocardial Infarction and Shock States. J Cardiovasc Pharmacol Ther. 2020 03; 25(2):103-109.. View in PubMed
Stunned and Hibernating Myocardium: Where Are We Nearly 4 Decades Later? J Am Heart Assoc. 2020 02 04; 9(3):e015502.. View in PubMed
The association of nadir CD4-T cell count and endothelial dysfunction in a healthy HIV cohort without major cardiovascular risk factors. SAGE Open Med. 2020; 8:2050312120924892.. View in PubMed
Cardiovascular effects of marijuana. Trends Cardiovasc Med. 2019 10; 29(7):403-407.. View in PubMed
Pathophysiology, Diagnosis, and Management of the No-Reflow Phenomenon. Cardiovasc Drugs Ther. 2019 10; 33(5):589-597.. View in PubMed
Lessons learned about stress and the heart after major earthquakes. Am Heart J. 2019 09; 215:20-26.. View in PubMed
Coronary artery calcium testing: A call for universal coverage. Prev Med Rep. 2019 Sep; 15:100879.. View in PubMed
Myocardial hypothermia induced after reperfusion does not prevent adverse left ventricular remodeling nor improve cardiac function. Life Sci. 2019 Jul 15; 229:98-103.. View in PubMed
Potential for stem cell-derived biologic pumps for cardiovascular and other medical therapies. Regen Med. 2019 07; 14(7):617-619.. View in PubMed
The Brain-Heart Connection and the Northridge Earthquake. Cardiol Rev. 2019 Jul/Aug; 27(4):171-172.. View in PubMed
The pharmacist’s role in improving the treatment of erectile dysfunction and its underlying causes. Res Social Adm Pharm. 2019 05; 15(5):591-599.. View in PubMed
Do We Need Potent Intravenous Antiplatelet Inhibition at the Time of Reperfusion During ST-Segment Elevation Myocardial Infarction? J Cardiovasc Pharmacol Ther. 2019 05; 24(3):215-224.. View in PubMed
Improved Long-term Survival with Remote Limb Ischemic Preconditioning in a Rat Fixed-Pressure Hemorrhagic Shock Model. Cardiovasc Drugs Ther. 2019 04; 33(2):139-147.. View in PubMed
Beyond Reperfusion: Acute Ventricular Unloading and Cardioprotection During Myocardial Infarction. J Cardiovasc Transl Res. 2019 04; 12(2):95-106.. View in PubMed
Proceedings of the 3rd annual Acute Cardiac Unloading and REcovery (A-CURE) symposium. BMC Cardiovasc Disord. 2019 02 07; 19(Suppl 2):27.. View in PubMed
A Thank You From the Editor-in-Chief. J Cardiovasc Pharmacol Ther. 2019 01; 24(1):90-91.. View in PubMed
Acute and Subacute Triggers of Cardiovascular Events. Am J Cardiol. 2018 12 15; 122(12):2157-2165.. View in PubMed
Effect of Patiromer in Hyperkalemic Patients Taking and Not Taking RAAS Inhibitors. J Cardiovasc Pharmacol Ther. 2018 11; 23(6):524-531.. View in PubMed
Cardiovascular Safety of Phosphodiesterase Type 5 Inhibitors After Nearly 2 Decades on the Market. Sex Med Rev. 2018 10; 6(4):583-594.. View in PubMed
No-reflow phenomenon in the heart and brain. Am J Physiol Heart Circ Physiol. 2018 09 01; 315(3):H550-H562.. View in PubMed
A New Perspective on the Nitrate-Phosphodiesterase Type 5 Inhibitor Interaction. J Cardiovasc Pharmacol Ther. 2018 09; 23(5):375-386.. View in PubMed
The Case for Takotsubo Cardiomyopathy (Syndrome) as a Variant of Acute Myocardial Infarction. Circulation. 2018 08 28; 138(9):855-857.. View in PubMed
No-Reflow Phenomenon. A New Target for Therapy of Acute Myocardial Infarction Independent of Myocardial Infarct Size. J Cardiovasc Pharmacol Ther. 2018 05; 23(3):273-276.. View in PubMed
Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol. 2018 04 01; 314(4):H812-H838.. View in PubMed
Cardiorenal Safety of OTC Analgesics. J Cardiovasc Pharmacol Ther. 2018 03; 23(2):103-118.. View in PubMed
The importance of no-reflow/microvascular obstruction in the STEMI patient. Eur Heart J. 2017 12 14; 38(47):3511-3513.. View in PubMed
The Oxygen Paradox, the French Paradox, and age-related diseases. Geroscience. 2017 12; 39(5-6):499-550.. View in PubMed
The authors reply. Crit Care Med. 2017 11; 45(11):e1201-e1202.. View in PubMed
New and revisited approaches to preserving the reperfused myocardium. Nat Rev Cardiol. 2017 Nov; 14(11):679-693.. View in PubMed
Mitochondrial Protective Agents for Ischemia/Reperfusion Injury. Circ Cardiovasc Interv. 2017 09; 10(9).. View in PubMed
Therapeutic Hypothermia Reduces the Inflammatory Response Following Ischemia/Reperfusion Injury in Rat Hearts. Ther Hypothermia Temp Manag. 2017 Sep; 7(3):162-170.. View in PubMed
The Cardiovascular Effects of Cocaine. J Am Coll Cardiol. 2017 Jul 04; 70(1):101-113.. View in PubMed
Noninvasive iPhone Measurement of Left Ventricular Ejection Fraction Using Intrinsic Frequency Methodology. Crit Care Med. 2017 Jul; 45(7):1115-1120.. View in PubMed
Delayed therapeutic hypothermia protects against the myocardial no-reflow phenomenon independently of myocardial infarct size in a rat ischemia/reperfusion model. Int J Cardiol. 2017 Jun 01; 236:400-404.. View in PubMed
Angina and Its Management. J Cardiovasc Pharmacol Ther. 2017 05; 22(3):199-209.. View in PubMed
Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations. Eur Heart J. 2017 04 01; 38(13):935-941.. View in PubMed
Heart Failure-Induced Brain Injury. J Am Coll Cardiol. 2017 Mar 28; 69(12):1609-1616.. View in PubMed
Management of No-Reflow Phenomenon in the Catheterization Laboratory. JACC Cardiovasc Interv. 2017 02 13; 10(3):215-223.. View in PubMed
Cardioprotection: Where to from here? Cardiovasc Drugs Ther. 2017 Feb; 31(1):53-61.. View in PubMed
Testosterone Replacement Therapy: New Data on Efficacy and Cardiovascular Safety. J Cardiovasc Pharmacol Ther. 2017 Jan; 22(1):54-55.. View in PubMed
Cardioprotective Effects of Mitochondria-Targeted Peptide SBT-20 in two Different Models of Rat Ischemia/Reperfusion. Cardiovasc Drugs Ther. 2016 Dec; 30(6):559-566.. View in PubMed
Cardiovascular Effects of Marijuana. J Cardiovasc Pharmacol Ther. 2016 09; 21(5):452-5.. View in PubMed
Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial). Am J Cardiol. 2016 09 01; 118(5):625-31.. View in PubMed
Reply: Testosterone and Cardiac Diastolic Function. J Am Coll Cardiol. 2016 08 02; 68(5):574-575.. View in PubMed
Approaches to Improving Cardiac Structure and Function During and After an Acute Myocardial Infarction: Acute and Chronic Phases. J Cardiovasc Pharmacol Ther. 2016 07; 21(4):363-7.. View in PubMed
Intravenous Beta-Blockade for Limiting Myocardial Infarct Size: Rejuvenation of a Concept. J Am Coll Cardiol. 2016 05 10; 67(18):2105-2107.. View in PubMed
EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention. Eur Heart J. 2016 Apr 21; 37(16):1296-303.. View in PubMed
Remote Ischemic Conditioning: Its Benefits and Limitations. J Cardiovasc Pharmacol Ther. 2016 Mar; 21(2):219-21.. View in PubMed
Testosterone and Cardiovascular Disease. J Am Coll Cardiol. 2016 Feb 09; 67(5):545-57.. View in PubMed
Letter to the editor response. Trends Cardiovasc Med. 2016 Feb; 26(2):203.. View in PubMed
Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart. Life Sci. 2015 Nov 15; 141:170-8.. View in PubMed
Relation of Total and Cardiovascular Death Rates to Climate System, Temperature, Barometric Pressure, and Respiratory Infection. Am J Cardiol. 2015 Oct 15; 116(8):1290-7.. View in PubMed
Cardiovascular consequences of cocaine use. Trends Cardiovasc Med. 2015 Aug; 25(6):517-26.. View in PubMed
Rapid Surface Cooling by ThermoSuit System Dramatically Reduces Scar Size, Prevents Post-Infarction Adverse Left Ventricular Remodeling, and Improves Cardiac Function in Rats. J Am Heart Assoc. 2015 Jun 26; 4(7).. View in PubMed
The safety and efficacy of peripheral vascular procedures performed in the outpatient setting. J Invasive Cardiol. 2015 May; 27(5):243-9.. View in PubMed
Testosterone and Cardiovascular Health: Safety of Treatment of Hypogonadism. Sex Med Rev. 2015 Mar; 3(1):56-62.. View in PubMed
Rapid Induction of Hypothermia by the ThermoSuit System Profoundly Reduces Infarct Size and Anatomic Zone of No Reflow Following Ischemia-Reperfusion in Rabbit and Rat Hearts. J Cardiovasc Pharmacol Ther. 2015 Mar; 20(2):193-202.. View in PubMed
New observations regarding post-ischemia/reperfusion myocardial swelling. J Am Coll Cardiol. 2015 Feb 03; 65(4):324-326.. View in PubMed
New therapies for reducing post-myocardial left ventricular remodeling. Ann Transl Med. 2015 Feb; 3(2):20.. View in PubMed
Dabigatran treatment: effects on infarct size and the no-reflow phenomenon in a model of acute myocardial ischemia/reperfusion. J Thromb Thrombolysis. 2015 Jan; 39(1):50-4.. View in PubMed
Rebuilding the infarcted heart with noncellular material. Regen Med. 2015; 10(6):683-5.. View in PubMed
Does sex influence the incidence or severity of reperfusion-induced cardiac arrhythmias? Springerplus. 2015; 4:96.. View in PubMed
Bendavia, a mitochondria-targeting peptide, improves postinfarction cardiac function, prevents adverse left ventricular remodeling, and restores mitochondria-related gene expression in rats. J Cardiovasc Pharmacol. 2014 Dec; 64(6):543-53.. View in PubMed
Hypothermia in the setting of experimental acute myocardial infarction: a comprehensive review. Ther Hypothermia Temp Manag. 2014 Dec; 4(4):159-67.. View in PubMed
Combined remote perconditioning and postconditioning failed to attenuate infarct size and contractile dysfunction in a rat model of coronary artery occlusion. J Cardiovasc Pharmacol Ther. 2014 Nov; 19(6):567-73.. View in PubMed
Ranolazine treatment for myocardial infarction? Effects on the development of necrosis, left ventricular function and arrhythmias in experimental models. Cardiovasc Drugs Ther. 2014 Oct; 28(5):469-75.. View in PubMed
Capsaicin-induced cardioprotection. Is hypothermia or the salvage kinase pathway involved? Cardiovasc Drugs Ther. 2014 Aug; 28(4):295-301.. View in PubMed
The Therapeutic Effect of Cell Transplantation Versus Noncellular Biomaterial Implantation on Cardiac Structure and Function Following Myocardial Infarction. J Cardiovasc Pharmacol Ther. 2014 Jul; 19(4):350-357.. View in PubMed
Functional and histological assessment of an experimental model of Takotsubo’s cardiomyopathy. J Am Heart Assoc. 2014 Jun 23; 3(3):e000921.. View in PubMed
A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 May; 65(5):968-78.. View in PubMed
Recreational marijuana use: is it safe for your patient? J Am Heart Assoc. 2014 Apr 23; 3(2):e000904.. View in PubMed
All men with vasculogenic erectile dysfunction require a cardiovascular workup. Am J Med. 2014 Mar; 127(3):174-82.. View in PubMed
Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know. Am J Cardiol. 2014 Jan 01; 113(1):187-90.. View in PubMed
Improved myocardial perfusion after transmyocardial laser revascularization in a patient with microvascular coronary artery disease. SAGE Open Med Case Rep. 2014; 2:2050313X14526873.. View in PubMed
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther. 2014 Jan; 19(1):121-32.. View in PubMed
Testosterone and the cardiovascular system: a comprehensive review of the clinical literature. J Am Heart Assoc. 2013 Nov 15; 2(6):e000272.. View in PubMed
Efficacy and safety of ranolazine in patients with chronic stable angina. Postgrad Med. 2013 Nov; 125(6):43-52.. View in PubMed
Super Bowl outcome’s association with cardiovascular death. Clin Res Cardiol. 2013 Nov; 102(11):807-11.. View in PubMed
Role of protein kinase C in ischemic “conditioning”: from first evidence to current perspectives. J Cardiovasc Pharmacol Ther. 2013 Nov; 18(6):525-32.. View in PubMed
The assessment of vascular risk in men with erectile dysfunction: the role of the cardiologist and general physician. Int J Clin Pract. 2013 Nov; 67(11):1163-72.. View in PubMed
Current state of clinical translation of cardioprotective agents for acute myocardial infarction. Circ Res. 2013 Aug 02; 113(4):451-63.. View in PubMed
Remote ischemic preconditioning for coronary artery bypass graft operations. Ann Thorac Surg. 2013 Aug; 96(2):727-36.. View in PubMed
Can myocardial infarct size be reduced by mechanically unloading the left ventricle? Circulation. 2013 Jul 23; 128(4):318-21.. View in PubMed
Testosterone and the cardiovascular system: a comprehensive review of the basic science literature. J Am Heart Assoc. 2013 Jul 10; 2(4):e000271.. View in PubMed
Sexual function in patients with chronic angina pectoris. Am J Cardiol. 2013 Jun 01; 111(11):1671-6.. View in PubMed
Diagnosis and treatment of erectile dysfunction for reduction of cardiovascular risk. J Urol. 2013 Jun; 189(6):2031-8.. View in PubMed
A brief review of useful tips for publishing your scientific manuscript. J Cardiovasc Pharmacol Ther. 2013 May; 18(3):197-8.. View in PubMed
Intramyocardial injection of heart tissue-derived extracellular matrix improves postinfarction cardiac function in rats. J Cardiovasc Pharmacol Ther. 2013 May; 18(3):270-9.. View in PubMed
Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction. Am Heart J. 2013 Apr; 165(4):509-514.e7.. View in PubMed
Phosphodiesterase type 5 inhibitors improve endothelial function and may benefit cardiovascular conditions. Am J Med. 2013 Mar; 126(3):192-9.. View in PubMed
Delayed treatment with hypothermia protects against the no-reflow phenomenon despite failure to reduce infarct size. J Am Heart Assoc. 2013 Jan 04; 2(1):e004234.. View in PubMed
Continuous heliox breathing and the extent of anatomic zone of noreflow and necrosis following ischemia/reperfusion in the rabbit heart. Open Cardiovasc Med J. 2013; 8:1-5.. View in PubMed
The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium. PLoS One. 2013; 8(9):e75010.. View in PubMed
Experience from experimental cell transplantation therapy of myocardial infarction: what have we learned? Cell Transplant. 2013; 22(3):563-8.. View in PubMed
Absence of actions of commonly used Chinese herbal medicines and electroacupuncture on myocardial infarct size. J Cardiovasc Pharmacol Ther. 2012 Dec; 17(4):403-11.. View in PubMed
The effect of acute versus delayed remote ischemic preconditioning on reperfusion induced ventricular arrhythmias. J Cardiovasc Electrophysiol. 2012 Dec; 23(12):1374-83.. View in PubMed
An apoptosis signal-regulating kinase 1 inhibitor reduces cardiomyocyte apoptosis and infarct size in a rat ischemia-reperfusion model. J Cardiovasc Pharmacol. 2012 Sep; 60(3):276-82.. View in PubMed
Therapeutic hypothermia for acute myocardial infarction and cardiac arrest. Am J Cardiol. 2012 Aug 01; 110(3):461-6.. View in PubMed
The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc. 2012 Aug; 87(8):766-78.. View in PubMed
Devices to treat peripheral chronic total occlusions. J Interv Cardiol. 2012 Aug; 25(4):395-403.. View in PubMed
Emotional stressors trigger cardiovascular events. Int J Clin Pract. 2012 Jul; 66(7):631-9.. View in PubMed
Unusual substrate underlying Brugada syndrome and early repolarization syndrome revealed in unusual circadian and seasonal patterns. J Cardiovasc Electrophysiol. 2012 Jul; 23(7):764-5.. View in PubMed
Prognostic utility of erectile dysfunction for cardiovascular disease in younger men and those with diabetes. Am Heart J. 2012 Jul; 164(1):21-8.. View in PubMed
Treating peripheral arterial disease percutaneously with atherectomy. J Invasive Cardiol. 2012 Jun; 24(6):263-9.. View in PubMed
Reduction of ischemia/reperfusion injury with bendavia, a mitochondria-targeting cytoprotective Peptide. J Am Heart Assoc. 2012 Jun; 1(3):e001644.. View in PubMed
How the 2008 stock market crash and seasons affect total and cardiac deaths in Los Angeles County. Am J Cardiol. 2012 May 15; 109(10):1445-8.. View in PubMed
Coronary no reflow. J Mol Cell Cardiol. 2012 Apr; 52(4):873-82.. View in PubMed
Treating Refractory Cardiogenic Shock With the TandemHeart and Impella Devices: A Single Center Experience. Cardiol Res. 2012 Apr; 3(2):54-66.. View in PubMed
Is inhibition of phosphodiesterase type 5 by sildenafil a promising therapy for volume-overload heart failure? Circulation. 2012 Mar 20; 125(11):1341-3.. View in PubMed
An update on cardioprotection: a review of the latest adjunctive therapies to limit myocardial infarction size in clinical trials. J Am Coll Cardiol. 2012 Mar 13; 59(11):969-78.. View in PubMed
Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2012 Feb 28; 125(8):1058-72.. View in PubMed
Cardiac uses of phosphodiesterase-5 inhibitors. J Am Coll Cardiol. 2012 Jan 03; 59(1):9-15.. View in PubMed
Genetically Engineered Mesenchymal Stem Cells Influence Gene Expression in Donor Cardiomyocytes and the Recipient Heart. J Stem Cell Res Ther. 2012; S1.. View in PubMed
Bone marrow-derived cell transplantation therapy for myocardial infarction: lessons learned and future questions. Am J Transplant. 2011 Nov; 11(11):2297-301.. View in PubMed
Investigational noncardiovascular uses of phosphodiesterase-5 inhibitors. Expert Opin Pharmacother. 2011 Oct; 12(15):2297-313.. View in PubMed
High-risk percutaneous coronary intervention with the TandemHeart and Impella devices: a single-center experience. J Invasive Cardiol. 2011 Oct; 23(10):417-24.. View in PubMed
Rotational Atherectomy and Stent Implantation for Calcified Left Main Lesions. Cardiol Res. 2011 Oct; 2(5):208-217.. View in PubMed
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation. 2011 Sep 06; 124(10):1172-9.. View in PubMed
No-reflow phenomenon: maintaining vascular integrity. J Cardiovasc Pharmacol Ther. 2011 Sep-Dec; 16(3-4):244-50.. View in PubMed
Introduction to proceedings of the NHLBI workshop: New Horizons in cardioprotection–a focused issue of journal of cardiovascular pharmacology and therapeutics. J Cardiovasc Pharmacol Ther. 2011 Sep-Dec; 16(3-4):222.. View in PubMed
State of the science of cardioprotection: Challenges and opportunities–proceedings of the 2010 NHLBI Workshop on Cardioprotection. J Cardiovasc Pharmacol Ther. 2011 Sep-Dec; 16(3-4):223-32.. View in PubMed
The antianginal agent ranolazine is a potent antiarrhythmic agent that reduces ventricular arrhythmias: through a mechanism favoring inhibition of late sodium channel. Cardiovasc Ther. 2011 Aug; 29(4):e36-41.. View in PubMed
Protecting the heart from ischemia: an update on ischemic and pharmacologic conditioning. Hosp Pract (1995). 2011 Aug; 39(3):35-43.. View in PubMed
Cardioprotection of insulin-like growth factor-1 during reperfusion therapy: what is the underlying mechanism or mechanisms? Circ Cardiovasc Interv. 2011 Aug; 4(4):311-3.. View in PubMed
Diannexin reduces no-reflow after reperfusion in rabbits with large ischemic myocardial risk zones. Cardiovasc Ther. 2011 Aug; 29(4):e42-52.. View in PubMed
First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model. J Cardiovasc Pharmacol Ther. 2011 Jun; 16(2):192-6.. View in PubMed
Mild hypothermia as a cardioprotective approach for acute myocardial infarction: laboratory to clinical application. J Cardiovasc Pharmacol Ther. 2011 Jun; 16(2):131-9.. View in PubMed
Cardiology patient page: cardiovascular implications of erectile dysfunction. Circulation. 2011 May 31; 123(21):e609-11.. View in PubMed
Rotational atherectomy in the drug-eluting stent era: a single-center experience. J Invasive Cardiol. 2011 Apr; 23(4):133-9.. View in PubMed
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Combination therapy for maximal myocardial infarct size reduction. Heart Dis. 2001 Nov-Dec; 3(6):351-6.. View in PubMed
Preinfarct angina and exercise: yet another reason to stay physically active. J Am Coll Cardiol. 2001 Nov 01; 38(5):1366-8.. View in PubMed
Effects of resveratrol, a flavinoid found in red wine, on infarct size in an experimental model of ischemia/reperfusion. J Stud Alcohol. 2001 Nov; 62(6):730-5.. View in PubMed
Seasonal variation of myocardial infarct size. Am J Cardiol. 2001 Nov 01; 88(9):1021-4.. View in PubMed
Ethanol does not exert myocardial preconditioning in an intact rabbit model of ischemia/reperfusion. Heart Dis. 2001 Sep-Oct; 3(5):293-6.. View in PubMed
Erectile dysfunction and cardiovascular risk factors. Hosp Pract (1995). 2001 Aug 15; 36(8):41-4, 49-51.. View in PubMed
Evidence for stunned myocardium in humans: a 2001 update. Coron Artery Dis. 2001 Aug; 12(5):349-56.. View in PubMed
Influence of embryonic cardiomyocyte transplantation on the progression of heart failure in a rat model of extensive myocardial infarction. J Mol Cell Cardiol. 2001 Jul; 33(7):1321-30.. View in PubMed
Can moderate alcohol intake limit the size of myocardial infarction? J Cardiovasc Pharmacol. 2001 Jun; 37(6):662-7.. View in PubMed
Ischemic preconditioning: implications for the geriatric heart. Am J Geriatr Cardiol. 2001 May-Jun; 10(3):145-8; quiz 149-51.. View in PubMed
p38 MAPK activity is not increased early during sustained coronary artery occlusion in preconditioned versus control rabbit heart. J Mol Cell Cardiol. 2001 Apr; 33(4):681-90.. View in PubMed
Comparative effects of candesartan cilexetil and amlodipine in patients with mild systemic hypertension. Comparison of Candesartan and Amlodipine for Safety, Tolerability and Efficacy (CASTLE) Study Investigators. Am J Cardiol. 2001 Mar 15; 87(6):727-31.. View in PubMed
Dissociation between improvement in angina pectoris and myocardial perfusion after transmyocardial revascularization with an excimer laser. Am J Cardiol. 2001 Jan 15; 87(2):229-31, A9.. View in PubMed
Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Sildenafil Study Group. Am J Hypertens. 2001 Jan; 14(1):70-3.. View in PubMed
Pretreatment with the gap junction uncoupler heptanol does not limit infarct size in rabbit heart. Cardiovasc Pathol. 2001 Jan-Feb; 10(1):13-7.. View in PubMed
Sildenafil citrate (Viagra) does not exacerbate myocardial ischemia in canine models of coronary artery stenosis. J Am Coll Cardiol. 2001 Jan; 37(1):286-92.. View in PubMed
Myocardial regeneration: present and future trends. Am J Cardiovasc Drugs. 2001; 1(4):233-44.. View in PubMed
Sex and the patient with cardiovascular risk factors: focus on sildenafil. Am J Med. 2000 Dec 18; 109 Suppl 9A:13S-21S; discussion 29S-30S.. View in PubMed
Adenosine A1 agonist at reperfusion trial (AART): results of a three-center, blinded, randomized, controlled experimental infarct study. Cardiovasc Drugs Ther. 2000 Dec; 14(6):607-14.. View in PubMed
Effect of combined K(ATP) channel activation and Na(+)/H(+) exchange inhibition on infarct size in rabbits. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H2673-7.. View in PubMed
Importance of asking questions about erectile dysfunction. Am J Cardiol. 2000 Dec 01; 86(11):1210-3, A5.. View in PubMed
Intramyocardial injection of DNA encoding vascular endothelial growth factor in a myocardial infarction model. J Thromb Thrombolysis. 2000 Dec; 10(3):285-9.. View in PubMed
Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription. Mol Cell Biol. 2000 Dec; 20(23):8643-54.. View in PubMed
What is the required reperfusion period for assessment of myocardial infarct size using triphenyltetrazolium chloride staining in the rat? J Thromb Thrombolysis. 2000 Oct; 10(2):181-7.. View in PubMed
Case 6: Renovascular hypertension. Am J Cardiol. 2000 Aug 01; 86(3):368-9.. View in PubMed
Cardiovascular risk and sildenafil. Am J Cardiol. 2000 Jul 20; 86(2A):57F-61F.. View in PubMed
Management of sexual dysfunction in patients with cardiovascular disease: recommendations of the Princeton Consensus Panel. Am J Cardiol. 2000 Jul 20; 86(2A):62F-68F.. View in PubMed
Management of sexual dysfunction in patients with cardiovascular disease: recommendations of The Princeton Consensus Panel. Am J Cardiol. 2000 Jul 15; 86(2):175-81.. View in PubMed
Case 5: hypertension and coronary artery disease. Am J Cardiol. 2000 Apr 15; 85(8):1039-40.. View in PubMed
Case 4: A patient with systemic hypertension and congestive heart failure. Am J Cardiol. 2000 Apr 01; 85(7):917-8, A10.. View in PubMed
Evaluation of the effects of intramyocardial injection of DNA expressing vascular endothelial growth factor (VEGF) in a myocardial infarction model in the rat–angiogenesis and angioma formation. J Am Coll Cardiol. 2000 Apr; 35(5):1323-30.. View in PubMed
Location as a determinant of myocardial infarction in rabbits. J Mol Cell Cardiol. 2000 Mar; 32(3):505-10.. View in PubMed
Biphasic survival response to amlodipine after myocardial infarction in rats: Association with cardiac vascular remodeling. Cardiovasc Pathol. 2000 Mar-Apr; 9(2):85-93.. View in PubMed
Case 3: A patient with systemic hypertension and left ventricular hypertrophy. Am J Cardiol. 2000 Feb 15; 85(4):522.. View in PubMed
Case 2: a patient with systemic hypertension and diabetes mellitus. Am J Cardiol. 2000 Jan 15; 85(2):273.. View in PubMed
A new model of ventricular plication: a suturing technique to decrease left ventricular dimensions, improve contractility, and attenuate ventricular remodeling after myocardial infarction in the rat heart. J Cardiovasc Pharmacol Ther. 2000 Jan; 5(1):41-9.. View in PubMed
Histologic signatures of thermal injury: applications in transmyocardial laser revascularization and radiofrequency ablation. Lasers Surg Med. 2000; 27(4):305-18.. View in PubMed
Hypertension as a Risk for Erectile Dysfunction: Implications for Sildenafil Use. J Clin Hypertens (Greenwich). 2000 Jan; 2(1):33-36.. View in PubMed
Case 1: isolated systolic hypertension. Am J Cardiol. 1999 Dec 15; 84(12):1452.. View in PubMed
Pharmacological manipulation of Ins(1,4,5)P3 signaling mimics preconditioning in rabbit heart. Am J Physiol. 1999 12; 277(6):H2458-69.. View in PubMed
When throughout the year is coronary death most likely to occur? A 12-year population-based analysis of more than 220 000 cases. Circulation. 1999 Oct 12; 100(15):1630-4.. View in PubMed
Cardiovascular effects of sildenafil citrate and recommendations for its use. Am J Cardiol. 1999 Sep 09; 84(5B):11N-17N.. View in PubMed
Brief myocardial ischemia attenuates platelet thrombosis in remote, damaged, and stenotic carotid arteries. Circulation. 1999 Aug 24; 100(8):843-8.. View in PubMed
Hibernating myocardium: is there evidence for chronic flow reduction? Heart Dis. 1999 Jul-Aug; 1(3):155-62.. View in PubMed
Clinical effects of ischemic preconditioning. Curr Opin Cardiol. 1999 Jul; 14(4):340-8.. View in PubMed
Cellular mechanisms of infarct size reduction with ischemic preconditioning. Role of calcium? Ann N Y Acad Sci. 1999 Jun 30; 874:192-210.. View in PubMed
Ischemic preconditioning and myocardial hypothermia in rabbits with prolonged coronary artery occlusion. Am J Physiol. 1999 06; 276(6):H2029-34.. View in PubMed
Natural disaster plus wake-up time: a deadly combination of triggers. Am Heart J. 1999 May; 137(5):779-81.. View in PubMed
Percutaneous transluminal coronary angioplasty as a model of ischemic preconditioning and preconditioning-mimetic drugs. J Am Coll Cardiol. 1999 Mar 15; 33(4):1036-9.. View in PubMed
Myocardial hypothermia: a potential therapeutic technique for acute regional myocardial ischemia. J Cardiovasc Electrophysiol. 1999 Mar; 10(3):405-13.. View in PubMed
Erectile dysfunction and sildenafil citrate and cardiologists. Am J Cardiol. 1999 Feb 15; 83(4):576-82, A7.. View in PubMed
Preconditioning-induced cardioprotection and release of the second messenger inositol (1,4,5)-trisphosphate are both abolished by neomycin in rabbit heart. Basic Res Cardiol. 1999 Feb; 94(1):31-40.. View in PubMed
Myocardial temperature reduction attenuates necrosis after prolonged ischemia in rabbits. Cardiovasc Res. 1998 Dec; 40(3):502-7.. View in PubMed
Evaluation of cardiac structures and function in small experimental animals: transthoracic, transesophageal, and intraventricular echocardiography to assess contractile function in rat heart. Basic Res Cardiol. 1998 Dec; 93(6):477-86.. View in PubMed
Role of protein kinase C as a cellular mediator of ischemic preconditioning: a critical review. Cardiovasc Res. 1998 Oct; 40(1):9-22.. View in PubMed
Viagra: what every physician should know. Ear Nose Throat J. 1998 Sep; 77(9):783-6.. View in PubMed
A small animal model of non-ischemic cardiomyopathy and its evaluation by transthoracic echocardiography. Cardiovasc Res. 1998 Jul; 39(1):216-23.. View in PubMed
Hypothermic, closed circuit pericardioperfusion: a potential cardioprotective technique in acute regional ischemia. J Am Coll Cardiol. 1998 Jun; 31(7):1667-71.. View in PubMed
Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop. Circulation. 1998 May 12; 97(18):1848-67.. View in PubMed
Ischemic preconditioning: exploring the paradox. Prog Cardiovasc Dis. 1998 May-Jun; 40(6):517-47.. View in PubMed
Ischemic preconditioning: the issues of refractoriness and tolerance. J Am Coll Cardiol. 1998 Apr; 31(5):1150-1.. View in PubMed
Temporal changes in the subcellular distribution of protein kinase C in rabbit heart during global ischemia. Basic Res Cardiol. 1998 Apr; 93(2):122-6.. View in PubMed
Prospective temporal analysis of the onset of preinfarction angina versus outcome: an ancillary study in TIMI-9B. Circulation. 1998 Mar 24; 97(11):1042-5.. View in PubMed
Brief antecedent ischemia attenuates platelet-mediated thrombosis in damaged and stenotic canine coronary arteries: role of adenosine. Circulation. 1998 Feb 24; 97(7):692-702.. View in PubMed
Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients. Am J Cardiol. 1998 Jan 15; 81(2):163-9.. View in PubMed
[Cardiomyocyte transplantation–a cell replacement for repair of myocardial infarction?]. Z Kardiol. 1998 Jan; 87(1):1-7.. View in PubMed
Population-based analysis of the effect of the Northridge Earthquake on cardiac death in Los Angeles County, California. J Am Coll Cardiol. 1997 Nov 01; 30(5):1174-80.. View in PubMed
Regional hypothermia reduces myocardial necrosis even when instituted after the onset of ischemia. Basic Res Cardiol. 1997 Oct; 92(5):351-7.. View in PubMed
Ischemic preconditioning at a distance: reduction of myocardial infarct size by partial reduction of blood supply combined with rapid stimulation of the gastrocnemius muscle in the rabbit. Circulation. 1997 Sep 02; 96(5):1641-6.. View in PubMed
Ischemic preconditioning. Curr Opin Cardiol. 1997 Sep; 12(5):475-81.. View in PubMed
Gene transfer and cell transplant: an experimental approach to repair a ‘broken heart’. Cardiovasc Res. 1997 Sep; 35(3):431-41.. View in PubMed
Is calcium a mediator of infarct size reduction with preconditioning in canine myocardium? Circulation. 1997 Aug 19; 96(4):1305-12.. View in PubMed
Intravenous co-infusion of adenosine and norepinephrine. J Thorac Cardiovasc Surg. 1997 Aug; 114(2):234-5.. View in PubMed
The effect of CY1503, a sialyl Lewisx analog blocker of the selectin adhesion molecules, on infarct size and “no-reflow” in the rabbit model of acute myocardial infarction/reperfusion. J Mol Cell Cardiol. 1997 Aug; 29(8):2013-25.. View in PubMed
Disparate effects of preconditioning and MLA on 5′-NT and adenosine levels during coronary occlusion. Am J Physiol. 1997 Aug; 273(2 Pt 2):H945-51.. View in PubMed
Myocardial temperature in acute myocardial infarction: protection with mild regional hypothermia. Am J Physiol. 1997 Jul; 273(1 Pt 2):H220-7.. View in PubMed
Changes in R wave amplitude: ECG differentiation between episodes of reocclusion and reperfusion associated with ST-segment elevation. J Electrocardiol. 1997 Jul; 30(3):211-6.. View in PubMed
Atherosclerotic cardiovascular mortality during the 1992 riots in Los Angeles. Am J Cardiol. 1997 Apr 15; 79(8):1155-8.. View in PubMed
Transmural channels as a source of blood flow to ischemic myocardium? Insights from the reptilian heart. Circulation. 1997 Mar 18; 95(6):1357-9.. View in PubMed
Characterization of collagen by high-frequency ultrasound: evidence for different acoustic properties based on collagen fiber morphologic characteristics. Am Heart J. 1997 Mar; 133(3):364-8.. View in PubMed
Clinical evidence that nisoldipine attenuates stunning in patients post infarction. Cardiovasc Drugs Ther. 1997 Mar; 11(1):17-8.. View in PubMed
Differences in reperfusion length following 30 minutes of ischemia in the rabbit influence infarct size, as measured by triphenyltetrazolium chloride staining. J Mol Cell Cardiol. 1997 Feb; 29(2):657-66.. View in PubMed
Is warm retrograde blood cardioplegia better than cold for myocardial protection? Ann Thorac Surg. 1997 Jan; 63(1):98-104.. View in PubMed
The issue of the cardiovascular safety of dihydropyridines. Am J Hypertens. 1996 Dec; 9(12 Pt 2):182S-186S.. View in PubMed
Myocardial viability. West J Med. 1996 Dec; 165(6):364-71.. View in PubMed
Direct evidence that ischemic preconditioning does not cause protein kinase C translocation in rabbit heart. Cardiovasc Res. 1996 Dec; 32(6):1064-70.. View in PubMed
The effect of coenzyme Q10 on infarct size in a rabbit model of ischemia/reperfusion. Cardiovasc Res. 1996 Nov; 32(5):861-8.. View in PubMed
Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myocardium? Circulation. 1996 Nov 01; 94(9 Suppl):II332-6.. View in PubMed
Adenovirus-mediated gene transfer into infarcted myocardium: feasibility, timing, and location of expression. J Mol Cell Cardiol. 1996 Oct; 28(10):2057-67.. View in PubMed
Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication-defective adenovirus. Circulation. 1996 Sep 15; 94(6):1394-401.. View in PubMed
Cardioprotection with ischemic preconditioning and MLA: role of adenosine-regulating enzymes? Am J Physiol. 1996 Sep; 271(3 Pt 2):H1004-14.. View in PubMed
Distortion of the terminal portion of the QRS on the admission electrocardiogram in acute myocardial infarction and correlation with infarct size and long-term prognosis (Thrombolysis in Myocardial Infarction 4 Trial). Am J Cardiol. 1996 Aug 15; 78(4):396-403.. View in PubMed
beta-Estradiol, but not alpha-estradiol, reduced myocardial necrosis in rabbits after ischemia and reperfusion. Am Heart J. 1996 Aug; 132(2 Pt 1):258-62.. View in PubMed
Preinfarction angina. N Engl J Med. 1996 Jul 04; 335(1):59-60; author reply 60-1.. View in PubMed
Progressive decrease in the ST segment elevation during ischemic preconditioning: is it related to recruitment of collateral vessels? J Mol Cell Cardiol. 1996 Jul; 28(7):1493-9.. View in PubMed
The Northridge earthquake as a trigger for acute myocardial infarction. Am J Cardiol. 1996 Jun 01; 77(14):1230-2.. View in PubMed
Intramyocardial injections and protection against myocardial ischemia. An attempt to examine the cardioprotective actions of adenosine. Circulation. 1996 Jun 01; 93(11):2043-57.. View in PubMed
Is preconditioning by nicotine responsible for the better prognosis in smokers with acute myocardial infarction? Basic Res Cardiol. 1996 May-Jun; 91(3):240-7.. View in PubMed
The open artery hypothesis: to open, or not to open, that is the question. Eur Heart J. 1996 Apr; 17(4):505-9.. View in PubMed
Sex- and age-related antihypertensive effects of amlodipine. The Amlodipine Cardiovascular Community Trial Study Group. Am J Cardiol. 1996 Apr 01; 77(9):713-22.. View in PubMed
Treatment of viral myocarditis with focus on captopril. Am J Cardiol. 1996 Mar 15; 77(8):634-7.. View in PubMed
Benefits of late coronary artery reperfusion on infarct expansion progressively diminish over time: relation to viable islets of myocytes within the scar. Am Heart J. 1996 Mar; 131(3):451-7.. View in PubMed
Sudden cardiac death triggered by an earthquake. N Engl J Med. 1996 Feb 15; 334(7):413-9.. View in PubMed
The hibernating myocardium. EXS. 1996; 76:453-62.. View in PubMed
Ischemic/reperfused myocardium can express recombinant protein following direct DNA or retroviral injection. J Mol Cell Cardiol. 1996 Jan; 28(1):133-40.. View in PubMed
Role of protein kinase C in ischemic preconditioning: in search of the “pure and simple truth”. Basic Res Cardiol. 1996 Jan-Feb; 91(1):41-3.. View in PubMed
Transmural channels can protect ischemic tissue. Assessment of long-term myocardial response to laser- and needle-made channels. Circulation. 1996 Jan 01; 93(1):143-52.. View in PubMed
Myocardial stunning: a post-ischemic syndrome with delayed recovery. EXS. 1996; 76:443-52.. View in PubMed
Preconditioning: a balanced perspective. Br Heart J. 1995 Dec; 74(6):575-7.. View in PubMed
Does ischemic preconditioning trigger translocation of protein kinase C in the canine model? Circulation. 1995 Sep 15; 92(6):1546-57.. View in PubMed
Effect of amlodipine on left ventricular mass in the Amlodipine Cardiovascular Community Trial. J Cardiovasc Pharmacol. 1995 Sep; 26(3):471-6.. View in PubMed
Transient pre-ischemic acidosis protects the isolated rabbit heart subjected to 30 minutes, but not 60 minutes, of global ischemia. Basic Res Cardiol. 1995 Sep-Oct; 90(5):397-403.. View in PubMed
Effect of two perfluorocarbon emulsions on reperfusion injury after coronary artery occlusion in rabbits. Basic Res Cardiol. 1995 Sep-Oct; 90(5):404-9.. View in PubMed
Nifedipine in ischemic heart disease. Circulation. 1995 Sep 01; 92(5):1074-8.. View in PubMed
Echocardiographic and cardiac Doppler assessment of mice. J Am Soc Echocardiogr. 1995 Sep-Oct; 8(5 Pt 1):602-10.. View in PubMed
Clinical aspects of myocardial stunning. Coron Artery Dis. 1995 Aug; 6(8):606-12.. View in PubMed
Low-dose i.v. acetylcholine acts as a “preconditioning-mimetic” in the canine model. J Card Surg. 1995 Jul; 10(4 Suppl):389-95.. View in PubMed
Therapy for myocardial stunning. Basic Res Cardiol. 1995 Jul-Aug; 90(4):291-3.. View in PubMed
Clinical aspects of preconditioning and implications for the cardiac surgeon. J Card Surg. 1995 Jul; 10(4 Suppl):369-75.. View in PubMed
An experimental model examining the role of magnesium in the therapy of acute myocardial infarction. Am J Cardiol. 1995 Jun 15; 75(17):1292-3.. View in PubMed
Gender does not influence acute myocardial infarction in adult dogs. Am Heart J. 1995 Jun; 129(6):1108-13.. View in PubMed
Basic view on the pathobiology of myocardial ischemia during coronary angioplasty: implications for cardiac protection. J Interv Cardiol. 1995 Jun; 8(3):291-9.. View in PubMed
Effects of previous angina pectoris in patients with first acute myocardial infarction not receiving thrombolytics. MILIS Study Group. Multicenter Investigation of the Limitation of Infarct Size. Am J Cardiol. 1995 Mar 15; 75(8):615-7.. View in PubMed
Quantitative two-dimensional echocardiographic assessment of regional wall motion during transient ischemia and reperfusion in the rat. J Am Soc Echocardiogr. 1995 Mar-Apr; 8(2):162-74.. View in PubMed
Do antioxidant vitamins reduce infarct size following acute myocardial ischemia/reperfusion? Cardiovasc Drugs Ther. 1995 Feb; 9(1):117-23.. View in PubMed
Preconditioning stimuli and inadvertent preconditioning. J Mol Cell Cardiol. 1995 Feb; 27(2):743-7.. View in PubMed
When and why do heart attacks occur? Cardiovascular triggers and their potential role. Hosp Pract (1995). 2010; 38(3):144-52.. View in PubMed
Previous angina alters in-hospital outcome in TIMI 4. A clinical correlate to preconditioning? Circulation. 1995 Jan 01; 91(1):37-45.. View in PubMed
Does protein kinase C play a role in ischemic preconditioning in rat hearts? Am J Physiol. 1995 Jan; 268(1 Pt 2):H426-31.. View in PubMed
Acute cocaine administration induces ventricular regional wall motion and ultrastructural abnormalities in an anesthetized rabbit model. Am Heart J. 1994 Dec; 128(6 Pt 1):1117-29.. View in PubMed
Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994 Oct; 94(4):1621-8.. View in PubMed
Tissue restricted gene expression assayed by direct DNA injection into cardiac and skeletal muscle. J Mol Cell Cardiol. 1994 Oct; 26(10):1393-401.. View in PubMed
Does ischemic preconditioning occur in patients? J Am Coll Cardiol. 1994 Oct; 24(4):1133-42.. View in PubMed
Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol. 1994 Sep-Oct; 89(5):397-410.. View in PubMed
Alpha-adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catecholamines mimics ischemic preconditioning. Circulation. 1994 Aug; 90(2):1023-8.. View in PubMed
Experience from experimental models in the quest to protect myocardium from ischemic damage: update on preconditioning strategies. Curr Opin Cardiol. 1994 Jul; 9(4):411-6.. View in PubMed
Protection of myocardium by transient, preischemic administration of phenylephrine in the rabbit. Coron Artery Dis. 1994 Jul; 5(7):605-10.. View in PubMed
Deterioration in myocardial blood flow following relief of sustained ischemia is not associated with release of endothelin into the coronary sinus. Basic Res Cardiol. 1994 May-Jun; 89(3):260-9.. View in PubMed
Clinical evidence for stunned myocardium after coronary artery bypass surgery. J Card Surg. 1994 May; 9(3 Suppl):397-402.. View in PubMed
Stunned myocardium following prolonged cardiopulmonary bypass: effect of warm versus cold cardioplegia in the canine model. J Card Surg. 1994 May; 9(3 Suppl):506-16.. View in PubMed
Time course of direct cardiotoxic effects of high cocaine concentration in isolated rabbit heart. J Cardiovasc Pharmacol. 1994 Mar; 23(3):509-16.. View in PubMed
Cardioprotective effects of ischemic preconditioning can be recaptured after they are lost. J Am Coll Cardiol. 1994 Feb; 23(2):470-4.. View in PubMed
Stretch preconditions canine myocardium. Am J Physiol. 1994 Jan; 266(1 Pt 2):H137-46.. View in PubMed
Cardiovascular applications of fluorocarbons in regional ischemia/reperfusion. Artif Cells Blood Substit Immobil Biotechnol. 1994; 22(4):1069-81.. View in PubMed
Stunning and angina. Am J Cardiol. 1993 Dec 15; 72(18):1456.. View in PubMed
An adenosine A1 receptor agonist, R(-)-N-(2-phenylisopropyl)-adenosine (PIA), but not adenosine itself, acts as a therapeutic preconditioning-mimetic agent in rabbits. Cardiovasc Res. 1993 Dec; 27(12):2140-5.. View in PubMed
Adenosine deaminase inhibition is not cardioprotective in the rat. Am Heart J. 1993 Dec; 126(6):1293-8.. View in PubMed
Ablation and coagulation of myocardial tissue by means of a pulsed holmium:YAG laser. Am Heart J. 1993 Dec; 126(6):1474-7.. View in PubMed
Acute myocardial infarction and diabetes mellitus. Cardiovasc Res. 1993 Nov; 27(11):1913-5.. View in PubMed
Can a few good cells now mend a broken heart? J Clin Invest. 1993 Sep; 92(3):1115-6.. View in PubMed
Does preconditioning protect the coronary vasculature from subsequent ischemia/reperfusion injury? Circulation. 1993 Aug; 88(2):659-72.. View in PubMed
Effects of cocaine on human platelets in healthy subjects. Am J Cardiol. 1993 Jul 15; 72(2):243-6.. View in PubMed
Laser-mediated transmural myocardial channels do not salvage acutely ischemic myocardium. J Am Coll Cardiol. 1993 Jul; 22(1):302-9.. View in PubMed
Oxygen radical scavenging agents as adjuvant therapy with tissue plasminogen activator in a canine model of coronary thrombolysis. Cardiovasc Res. 1993 Jun; 27(6):925-34.. View in PubMed
The cardioprotective effects of ischemic ‘preconditioning’ are not mediated by adenosine receptors in rat hearts. Circulation. 1993 May; 87(5):1642-8.. View in PubMed
Ischemic preconditioning and long-chain acyl carnitine in the canine heart. Coron Artery Dis. 1993 Apr; 4(4):387-92.. View in PubMed
Flow-function dissociation following an acute dose of cocaine: effect of captopril on coronary flow. Coron Artery Dis. 1993 Mar; 4(3):271-6.. View in PubMed
Unraveling the complex effects of cocaine on the heart. Circulation. 1993 Mar; 87(3):1046-7.. View in PubMed
Regional ischemic ‘preconditioning’ protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation. 1993 Mar; 87(3):893-9.. View in PubMed
Understanding the jargon: a glossary of terms used (and misused) in the study of ischaemia and reperfusion. Cardiovasc Res. 1993 Feb; 27(2):162-6; discussion 167-71.. View in PubMed
Cardioprotection with angiotensin-converting enzyme inhibitors: redefined for the 1990s. Clin Cardiol. 1993 Feb; 16(2):95-103.. View in PubMed
Does reperfusion injury exist in humans? J Am Coll Cardiol. 1993 Feb; 21(2):537-45.. View in PubMed
“Cardioprotection” by ACE-inhibitors in acute myocardial ischemia and infarction? Basic Res Cardiol. 1993; 88 Suppl 1:139-54.. View in PubMed
Partial coronary stenosis is sufficient and complete reperfusion is mandatory for preconditioning the canine heart. Circ Res. 1992 Nov; 71(5):1165-73.. View in PubMed
Effects of amlodipine on myocardial infarction, infarct expansion, and ventricular geometry in the rat. Am Heart J. 1992 Sep; 124(3):571-80.. View in PubMed
Coronary angioplasty: a treatment option for left ventricular remodeling after myocardial infarction? J Am Coll Cardiol. 1992 Aug; 20(2):314-6.. View in PubMed
Recombinant tissue-type plasminogen activator: an infarct-sparing effect beyond thrombolysis? J Am Coll Cardiol. 1992 Jul; 20(1):226-7.. View in PubMed
Preconditioning does not attenuate myocardial stunning. Circulation. 1992 Jun; 85(6):2247-54.. View in PubMed
Reperfusion of hibernating myocardium: contractile function, high-energy phosphate content, and myocyte injury after 3 hours of sublethal ischemia and 3 hours of reperfusion in the canine model. Am Heart J. 1992 Mar; 123(3):575-88.. View in PubMed
Cardioprotective effects of ischaemic preconditioning are not mediated by prostanoids. Cardiovasc Res. 1992 Mar; 26(3):226-31.. View in PubMed
The effects of acute and chronic cocaine use on the heart. Circulation. 1992 Feb; 85(2):407-19.. View in PubMed
Coronary cyclic flow variations “precondition” ischemic myocardium. Circulation. 1992 Feb; 85(2):779-89.. View in PubMed
The transient nature of the effect of ischemic preconditioning on myocardial infarct size and ventricular arrhythmia. Am Heart J. 1992 Feb; 123(2):346-53.. View in PubMed
Calcium antagonists and the stunned myocardium: a role during ischaemia? A role during reperfusion? Cardiovasc Res. 1992 Jan; 26(1):82-4.. View in PubMed
Absence of hemodynamic deterioration in the presence of amlodipine following experimental myocardial infarction. J Cardiovasc Pharmacol. 1992; 20(5):837-45.. View in PubMed
Hibernation and stunning of the myocardium. N Engl J Med. 1991 Dec 26; 325(26):1877-9.. View in PubMed
Flow support catheter for prolonged maintenance of coronary blood flow. Cathet Cardiovasc Diagn. 1991 Dec; 24(4):308-14.. View in PubMed
Role of collagen in acute myocardial infarct expansion. Circulation. 1991 Nov; 84(5):2123-34.. View in PubMed
Influx of neutrophils into the walls of large epicardial coronary arteries in response to ischemia/reperfusion. Circulation. 1991 Oct; 84(4):1758-72.. View in PubMed
Calcium antagonists and stunned myocardium: importance for clinicians? Cardiovasc Drugs Ther. 1991 Oct; 5(5):947-51.. View in PubMed
Pretreatment with the iron chelator desferrioxamine fails to provide sustained protection against myocardial ischaemia-reperfusion injury. Cardiovasc Res. 1991 Sep; 25(9):711-8.. View in PubMed
Experimental infarct size reduction with calcium channel blockers. J Am Coll Cardiol. 1991 Sep; 18(3):876-8.. View in PubMed
Stunned left ventricular myocardium after exercise treadmill testing in coronary artery disease. Am J Cardiol. 1991 Aug 01; 68(4):329-34.. View in PubMed
Angiotensin converting enzyme inhibitors improve contractile function of stunned myocardium by different mechanisms of action. Am Heart J. 1991 May; 121(5):1319-30.. View in PubMed
Congestive heart failure. New frontiers. West J Med. 1991 Apr; 154(4):427-41.. View in PubMed
Nifedipine protects the heart from the acute deleterious effects of cocaine if administered before but not after cocaine. Circulation. 1991 Apr; 83(4):1437-43.. View in PubMed
Lack of significant effects of superoxide dismutase and catalase on development of reperfusion arrhythmias. Basic Res Cardiol. 1991 Mar-Apr; 86(2):127-35.. View in PubMed
Stunned myocardium and myocardial collagen damage: differential effects of single and repeated occlusions. Am Heart J. 1991 Feb; 121(2 Pt 1):434-41.. View in PubMed
Stunned and hibernating myocardium. Annu Rev Med. 1991; 42:1-8.. View in PubMed
Calcium antagonists and the stunned myocardium. J Cardiovasc Pharmacol. 1991; 18 Suppl 10:S93-101.. View in PubMed
Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat. Circ Res. 1991 Jan; 68(1):61-8.. View in PubMed
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The effect of balloon angioplasty on vasa vasorum blood flow in canine coronary arteries. Am Heart J. 1990 Dec; 120(6 Pt 1):1285-91.. View in PubMed
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Left main percutaneous transluminal coronary angioplasty with the autoperfusion catheter in an animal model. Cathet Cardiovasc Diagn. 1990 Sep; 21(1):45-50.. View in PubMed
In vivo infusion of oxygen free radical substrates causes myocardial systolic, but not diastolic dysfunction. Am Heart J. 1990 Apr; 119(4):807-15.. View in PubMed
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Beneficial effects of captopril in acute coxsackievirus B3 murine myocarditis. Circulation. 1990 Mar; 81(3):1039-46.. View in PubMed
No reflow revisited. J Am Coll Cardiol. 1989 Dec; 14(7):1814-5.. View in PubMed
Adverse effects of cocaine on cardiovascular dynamics, myocardial blood flow, and coronary artery diameter in an experimental model. Am Heart J. 1989 Nov; 118(5 Pt 1):927-33.. View in PubMed
Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues. Circulation. 1989 Nov; 80(5):1115-27.. View in PubMed
The autoperfusion balloon angioplasty catheter limits myocardial ischemia and necrosis during prolonged balloon inflation. J Am Coll Cardiol. 1989 Oct; 14(4):1045-50.. View in PubMed
What factors predict recovery of contractile function in the canine model of the stunned myocardium? Am J Cardiol. 1989 Sep 19; 64(11):18F-26F.. View in PubMed
Is “stunned myocardium” a protective mechanism? Effect of acute recruitment and acute beta-blockade on recovery of contractile function and high-energy phosphate stores at 1 day post-reperfusion. Am Heart J. 1989 Sep; 118(3):480-9.. View in PubMed
Electrocardiographic abnormalities after acute administration of cocaine in the rat. Am J Cardiol. 1989 Jun 15; 63(20):1529-30.. View in PubMed
Does tissue-type plasminogen activator have direct beneficial effects on the myocardium independent of its ability to lyse intracoronary thrombi? Circulation. 1989 May; 79(5):1125-36.. View in PubMed
The clinical syndrome of 5-fluorouracil cardiotoxicity. Invest New Drugs. 1989 Apr; 7(1):101-9.. View in PubMed
Continuous ambulatory ECG monitoring during fluorouracil therapy: a prospective study. J Clin Oncol. 1989 Apr; 7(4):509-14.. View in PubMed
Analysis of healing after myocardial infarction using polarized light microscopy. Am J Pathol. 1989 Apr; 134(4):879-93.. View in PubMed
Do neutrophils mediate the phenomenon of stunned myocardium? J Am Coll Cardiol. 1989 Apr; 13(5):1164-6.. View in PubMed
Nifedipine administered after reperfusion ablates systolic contractile dysfunction of postischemic “stunned” myocardium. J Am Coll Cardiol. 1989 Apr; 13(5):1176-83.. View in PubMed
Management strategies in viral myocarditis. Am Heart J. 1989 Mar; 117(3):706-8.. View in PubMed
Detection of experimental myocarditis by monoclonal antimyosin antibody, Fab fragment. Am Heart J. 1989 Feb; 117(2):391-5.. View in PubMed
Altered myocardial states. The stunned and hibernating myocardium. Am J Med. 1989 Jan 16; 86(1A):14-22.. View in PubMed
Relationships between structure and effects of ACE inhibitors: comparative effects in myocardial ischaemic/reperfusion injury. Br J Clin Pharmacol. 1989; 28 Suppl 2:167S-175S.. View in PubMed
Early treatment with deferoxamine limits myocardial ischemic/reperfusion injury. Free Radic Biol Med. 1989; 7(1):45-52.. View in PubMed
“Reperfusion injury” by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow. Circ Res. 1989 Jan; 64(1):86-96.. View in PubMed
Left ventricular topographic alterations in the completely healed rat infarct caused by early and late coronary artery reperfusion. Am Heart J. 1988 Dec; 116(6 Pt 1):1508-13.. View in PubMed
Diastolic filling in acute left ventricular dysfunction: role of the pericardium. J Am Coll Cardiol. 1988 Nov; 12(5):1326-33.. View in PubMed
Amelioration of ischemia during angioplasty of the left anterior descending coronary artery with an autoperfusion catheter. Am J Cardiol. 1988 Sep 15; 62(9):513-7.. View in PubMed
Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs. Circulation. 1988 Aug; 78(2):428-34.. View in PubMed
Effect of metoprolol in acute coxsackievirus B3 murine myocarditis. J Am Coll Cardiol. 1988 Aug; 12(2):412-4.. View in PubMed
Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. J Lab Clin Med. 1988 Jul; 112(1):118-21.. View in PubMed
Atrial natriuretic peptide in acute coxsackievirus murine myocarditis. Am J Cardiol. 1988 Jun 01; 61(15):1361-2.. View in PubMed
Calcium channel blockade during ischemia-reperfusion sequences. J Mol Cell Cardiol. 1988 May; 20(5):457-9.. View in PubMed
Postischemic myocardial “stunning”: a clinically relevant phenomenon. Ann Intern Med. 1988 Apr; 108(4):626-8.. View in PubMed
Functional infarct expansion, left ventricular dilation and isovolumic relaxation time after coronary occlusion: a two-dimensional echocardiographic study. J Am Coll Cardiol. 1988 Mar; 11(3):630-6.. View in PubMed
Effect of verapamil on postischemic “stunned” myocardium: importance of the timing of treatment. J Am Coll Cardiol. 1988 Mar; 11(3):614-23.. View in PubMed
Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction. Br J Pharmacol. 1988 Mar; 93(3):587-90.. View in PubMed
Introduction to the role of oxygen radicals in myocardial ischemia and infarction. Free Radic Biol Med. 1988; 4(1):5-7.. View in PubMed
Effect of myocyte necrosis on strength, strain, and stiffness of isolated myocardial strips. Am Heart J. 1987 Dec; 114(6):1349-59.. View in PubMed
Diastolic abnormalities of postischemic “stunned” myocardium. Am J Cardiol. 1987 Nov 15; 60(14):1211-3.. View in PubMed
Acute effects of hydralazine and enalapril on contractile function of postischemic “stunned” myocardium. Am J Cardiol. 1987 Oct 01; 60(10):934-6.. View in PubMed
5-Fluorouracil cardiotoxicity: left ventricular dysfunction and effect of coronary vasodilators. Am J Med Sci. 1987 Oct; 294(4):238-43.. View in PubMed
Effects of acid base disturbance, septic shock, and calcium and phosphorous abnormalities on cardiovascular function. Crit Care Clin. 1987 Oct; 3(4):747-58.. View in PubMed
Effect of early coronary artery reperfusion on infarct development in a model of low collateral flow. Cardiovasc Res. 1987 Sep; 21(9):668-73.. View in PubMed
Effects of methylprednisolone on collagen biosynthesis in healing acute myocardial infarction. Am J Cardiol. 1987 Aug 01; 60(4):424-5.. View in PubMed
Effect of milrinone on acute myocardial infarct size. Am J Cardiol. 1987 Aug 01; 60(4):422-3.. View in PubMed
The effect of digitalis on experimental myocardial infarct size and hemodynamics. Am Heart J. 1987 Jun; 113(6):1353-5.. View in PubMed
Preservation of distal coronary perfusion during prolonged balloon inflation with an autoperfusion angioplasty catheter. Circulation. 1987 Jun; 75(6):1273-80.. View in PubMed
Coronary reperfusion following experimental myocardial infarction. J Card Surg. 1987 Jun; 2(2):291-7.. View in PubMed
Differential effects of reperfusion on incidence of ventricular arrhythmias and recovery of ventricular function at 4 days following coronary occlusion. Am Heart J. 1987 May; 113(5):1055-65.. View in PubMed
Structural and metabolic correlates of cell injury in the hypertrophied myocardium during valve replacement. J Thorac Cardiovasc Surg. 1987 May; 93(5):741-54.. View in PubMed
Acute myocardial infarction: diagnostic and prognostic applications of two-dimensional echocardiography. Circulation. 1987 Mar; 75(3):521-4.. View in PubMed
Analysis of reported randomized trials of streptokinase therapy for acute myocardial infarction in the 1980s. Am J Cardiol. 1987 Mar 01; 59(6):501-4.. View in PubMed
Effect of oxygen-derived free radical scavengers on infarct size following six hours of permanent coronary artery occlusion: salvage or delay of myocyte necrosis? Basic Res Cardiol. 1987 Mar-Apr; 82(2):146-58.. View in PubMed
The cardiotonic agent amrinone does not increase anatomic infarct size. J Cardiovasc Pharmacol. 1987 Feb; 9(2):225-9.. View in PubMed
Effects of calcium antagonists on infarcting myocardium. Am J Cardiol. 1987 Jan 30; 59(3):84B-94B.. View in PubMed
Inability of fructose 1,6-diphosphate to reduce myocardial infarct size. J Med. 1987; 18(1):43-53.. View in PubMed
Effect of verapamil on infarct size in dogs subjected to coronary artery occlusion with transient reperfusion. J Am Coll Cardiol. 1986 Nov; 8(5):1169-74.. View in PubMed
Fluorescent microspheres: a new tool for visualization of ischemic myocardium in rats. Am J Physiol. 1986 Oct; 251(4 Pt 2):H863-8.. View in PubMed
Effect of reperfusion and hyperemia on the myocardial distribution of technetium-99m t-butylisonitrile. J Nucl Med. 1986 Jul; 27(7):1172-7.. View in PubMed
Salvage of ischaemic myocardium by reperfusion: importance of collateral blood flow and myocardial oxygen demand during occlusion. Cardiovasc Res. 1986 Jun; 20(6):403-14.. View in PubMed
Usefulness of intracoronary infusion of fluorocarbon distal to prolonged coronary occlusion by angioplasty balloon in dogs. Am J Cardiol. 1986 May 01; 57(13):1202-5.. View in PubMed
Infarct size reduction: a review of the clinical trials. J Clin Pharmacol. 1986 May-Jun; 26(5):317-29.. View in PubMed
Superoxide dismutase plus catalase improve contractile function in the canine model of the “stunned myocardium”. Circ Res. 1986 Jan; 58(1):148-56.. View in PubMed
Capillary anastomoses between the left anterior descending and circumflex circulations in the canine heart: possible importance during coronary artery occlusion. Microvasc Res. 1986 Jan; 31(1):54-65.. View in PubMed
Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats. Am J Pathol. 1985 Dec; 121(3):522-30.. View in PubMed
Inotropic stimulation of reperfused myocardium with dopamine: effects on infarct size and myocardial function. J Am Coll Cardiol. 1985 Nov; 6(5):1026-34.. View in PubMed
Myocardial reperfusion: a double-edged sword? J Clin Invest. 1985 Nov; 76(5):1713-9.. View in PubMed
Contrast echocardiographic estimation of regional myocardial blood flow after acute coronary occlusion. Circulation. 1985 Nov; 72(5):1115-24.. View in PubMed
Experimental and clinical observations on the efficacy of esmolol in myocardial ischemia. Am J Cardiol. 1985 Oct 23; 56(11):40F-48F.. View in PubMed
Use of an ultra short-acting beta-blocker in patients with acute myocardial ischemia. Circulation. 1985 Oct; 72(4):873-80.. View in PubMed
Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue. Circ Res. 1985 Oct; 57(4):562-77.. View in PubMed
Effect of intracoronary verapamil on infarct size in the ischemic, reperfused canine heart: critical importance of the timing of treatment. Am J Cardiol. 1985 Oct 01; 56(10):672-7.. View in PubMed
Alterations in the distribution of high-energy phosphates during ischemia in a canine model of reperfusion-induced ventricular fibrillation. Am Heart J. 1985 Sep; 110(3):590-4.. View in PubMed
Relation between the transmural extent of acute myocardial infarction and associated myocardial contractility two weeks after infarction. Am J Cardiol. 1985 May 01; 55(11):1412-6.. View in PubMed
The significance of the late fall in myocardial PCO2 and its relationship to myocardial pH after regional coronary occlusion in the dog. Circ Res. 1985 Apr; 56(4):537-47.. View in PubMed
Effects of nisoldipine, a new calcium antagonist, on myocardial infarct size and cardiac dynamics following acute myocardial infarction. J Cardiovasc Pharmacol. 1985 Mar-Apr; 7(2):361-7.. View in PubMed
Relation of early mononuclear and polymorphonuclear cell infiltration to late scar thickness after experimentally induced myocardial infarction in the rat. Basic Res Cardiol. 1985 Mar-Apr; 80(2):202-9.. View in PubMed
Effects of transient increased afterload during experimentally induced acute myocardial infarction in dogs. Am J Cardiol. 1985 Feb 15; 55(5):566-70.. View in PubMed
Overview of the use of perfluorochemicals for myocardial ischemic rescue. Int Anesthesiol Clin. 1985; 23(1):115-30.. View in PubMed
Preservation of high-energy phosphates by verapamil in reperfused myocardium. Circulation. 1984 Oct; 70(4):734-41.. View in PubMed
Dissociation between two-dimensional echocardiographic left ventricular wall motion and myocardial salvage in early experimental acute myocardial infarction in dogs. Am J Cardiol. 1984 Oct 01; 54(7):875-9.. View in PubMed
Quantitative analysis of left ventricular function: pre- and postischemic two-dimensional echocardiography in dogs. AJR Am J Roentgenol. 1984 Sep; 143(3):537-42.. View in PubMed
The effect of streptokinase on intramyocardial hemorrhage, infarct size, and the no-reflow phenomenon during coronary reperfusion. Circulation. 1984 Sep; 70(3):513-21.. View in PubMed
The relative importance of alkalinity, temperature, and the washout effect of bicarbonate-buffered, multidose cardioplegic solution. Circulation. 1984 Sep; 70(3 Pt 2):I75-83.. View in PubMed
Early and late remodeling of the left ventricle after acute myocardial infarction. Am J Cardiol. 1984 Aug 01; 54(3):407-10.. View in PubMed
Effects of recurrent ischemia on myocardial high energy phosphate content in canine hearts. Basic Res Cardiol. 1984 Jul-Aug; 79(4):469-78.. View in PubMed
Enhancement of salvage of reperfused myocardium by early beta-adrenergic blockade (timolol). J Am Coll Cardiol. 1984 Jun; 3(6):1438-43.. View in PubMed
Correlates of reperfusion ventricular fibrillation in dogs. Am J Cardiol. 1984 May 01; 53(9):1397-400.. View in PubMed
Heparin inhibits bovine testicular hyaluronidase activity in myocardium of dogs with coronary artery occlusion. Am J Cardiol. 1984 Mar 15; 53(7):941-4.. View in PubMed
Drug-induced expansion of infarct: morphologic and functional correlations. Circulation. 1984 Mar; 69(3):611-7.. View in PubMed
Morphologic and functional effects of piroxicam on myocardial scar formation after coronary occlusion in dogs. Am J Cardiol. 1984 Feb 01; 53(4):604-7.. View in PubMed
Absence of a cumulative deterioration of regional function during three repeated 5 or 15 minute coronary occlusions. Circulation. 1984 Feb; 69(2):400-8.. View in PubMed
Response of reperfusion-salvaged, stunned myocardium to inotropic stimulation. Am Heart J. 1984 Jan; 107(1):13-9.. View in PubMed
Failure of pindolol and metoprolol to reduce the size of non-reperfused infarcts in dogs using area at risk techniques. Cardiovasc Res. 1984 Jan; 18(1):37-43.. View in PubMed
Short-term exercise has a prolonged effect on scar formation after experimental acute myocardial infarction. J Am Coll Cardiol. 1983 Nov; 2(5):979-82.. View in PubMed
The effect of early exercise on myocardial infarct scar formation. Am Heart J. 1983 Nov; 106(5 Pt 1):1009-13.. View in PubMed
Effect of coronary reperfusion on myocardial hemorrhage and infarct healing. Am J Cardiol. 1983 Sep 01; 52(5):610-4.. View in PubMed
Hydrogen peroxide contrast–enhanced two-dimensional echocardiography: real-time in vivo delineation of regional myocardial perfusion. Circulation. 1983 Sep; 68(3):603-11.. View in PubMed
Interactions between coronary occlusion and the renin-angiotensin system in the dog. Basic Res Cardiol. 1983 Sep-Oct; 78(5):518-33.. View in PubMed
Time course of ischemic alterations during normothermic and hypothermic arrest and its reflection by on-line monitoring of tissue pH. J Thorac Cardiovasc Surg. 1983 Sep; 86(3):418-34.. View in PubMed
A flow- and time-dependent index of ischemic injury after experimental coronary occlusion and reperfusion. Proc Natl Acad Sci U S A. 1983 Sep; 80(18):5784-8.. View in PubMed
Dose-dependent effects of short-term methylprednisolone on myocardial infarct extent, scar formation, and ventricular function. Circulation. 1983 Aug; 68(2):446-52.. View in PubMed
Studies of experimental coronary artery reperfusion. Effects on infarct size, myocardial function, biochemistry, ultrastructure and microvascular damage. Circulation. 1983 Aug; 68(2 Pt 2):I8-15.. View in PubMed
Indomethacin-induced scar thinning after experimental myocardial infarction. Circulation. 1983 Jun; 67(6):1290-5.. View in PubMed
Quantitative detection of regional left ventricular contraction abnormalities by 2-dimensional echocardiography. Comparison of myocardial thickening and thinning and endocardial motion in a canine model. Am J Cardiol. 1983 Jun; 51(10):1732-8.. View in PubMed
First ultra-short-acting beta-adrenergic blocking agent: its effect on size and segmental wall dynamics of reperfused myocardial infarcts in dogs. Am J Cardiol. 1983 Jun; 51(10):1759-67.. View in PubMed
Effects of ortho-iodo sodium benzoate on acute myocardial ischemia, hemodynamic function, and infarct size after coronary artery occlusion in dogs. Am J Cardiol. 1983 May 01; 51(8):1422-7.. View in PubMed
Time course of functional and biochemical recovery of myocardium salvaged by reperfusion. J Am Coll Cardiol. 1983 Apr; 1(4):1047-55.. View in PubMed
Topographic changes in the left ventricle after experimentally induced myocardial infarction in the rat. Am J Cardiol. 1983 Mar 01; 51(5):872-6.. View in PubMed
Scar thinning due to ibuprofen administration after experimental myocardial infarction. Am J Cardiol. 1983 Mar 01; 51(5):877-83.. View in PubMed
Special notice. Am J Physiol. 1983 Mar; 244(3):H470.. View in PubMed
Role of beta-adrenergic blockade in the therapy of patients with myocardial infarction. Am J Med. 1983 Jan; 74(1):113-23.. View in PubMed
The effect of perfluorocarbons on experimental myocardial ischemia and infarction. Prog Clin Biol Res. 1983; 122:381-90.. View in PubMed
Coronary reperfusion for the treatment of acute myocardial infarction: postischemic ventricular dysfunction. Cardiology. 1983; 70(5):233-46.. View in PubMed
The stunned myocardium: prolonged, postischemic ventricular dysfunction. Circulation. 1982 Dec; 66(6):1146-9.. View in PubMed
Retraction: border zone salvage by flurbiprofen. Circulation. 1982 Nov; 66(5):1136.. View in PubMed
Enhanced detection of the evolution of tissue changes after acute myocardial infarction using color-encoded two-dimensional echocardiography. Circulation. 1982 Oct; 66(4):764-70.. View in PubMed
Withdrawal of 2 previously published reports. Am J Cardiol. 1982 Oct; 50(4):929.. View in PubMed
Retraction of: Early recovery of regional performance in salvaged ischemic myocardium following coronary artery occlusion in the dog. J Clin Invest. 1982 Oct; 70(4):following 915.. View in PubMed
Limitation of myocardial infarct size after surgical reperfusion for acute coronary occlusion. J Thorac Cardiovasc Surg. 1982 Sep; 84(3):353-8.. View in PubMed
Inosine: a protective agent in an organ culture model of myocardial ischemia. Circ Res. 1982 Aug; 51(2):181-8.. View in PubMed
Serial evaluation of myocardial thickening and thinning in acute experimental infarction: identification and quantification using two-dimensional echocardiography. Circulation. 1982 Jul; 66(1):174-80.. View in PubMed
Effects of intravenous fluorocarbons during and without oxygen enhancement on acute myocardial ischemic injury assessed by measurement of intramyocardial gas tensions. Am Heart J. 1982 Jun; 103(6):986-95.. View in PubMed
The effect of verapamil on myocardial ultrastructure during and following release of coronary artery occlusion. Exp Mol Pathol. 1982 Jun; 36(3):277-86.. View in PubMed
Studies of amiodarone during experimental myocardial infarction: beneficial effects on hemodynamics and infarct size. Circulation. 1982 Mar; 65(3):508-12.. View in PubMed
The effects of early indomethacin administration on late scar formation following myocardial infarction. Trans Assoc Am Physicians. 1982; 95:104-9.. View in PubMed
Limitation of experimental infarct size by an angiotensin-converting enzyme inhibitor. Circulation. 1982 Jan; 65(1):40-8.. View in PubMed
Recovery from prolonged abnormalities of canine myocardium salvaged from ischemic necrosis by coronary reperfusion. Proc Natl Acad Sci U S A. 1981 Nov; 78(11):7152-6.. View in PubMed
Dependency of location of salvageable myocardium on type of intervention. Am J Cardiol. 1981 Oct; 48(4):702-10.. View in PubMed
Prolonged abnormalities of myocardium salvaged by reperfusion. Am J Physiol. 1981 Oct; 241(4):H591-9.. View in PubMed
Early pathologic detection of acute myocardial infarction. Arch Pathol Lab Med. 1981 Aug; 105(8):403-6.. View in PubMed
Early recovery of regional performance in salvaged ischemic myocardium following coronary artery occlusion in the dog. J Clin Invest. 1981 Jul; 68(1):225-39.. View in PubMed
Fluorocarbons reduce myocardial ischemic damage after coronary occlusion. Science. 1981 Mar 27; 211(4489):1439-41.. View in PubMed
Time course of regional function after coronary occlusions of 1- to 120-min duration. Am J Physiol. 1981 Mar; 240(3):H399-407.. View in PubMed
Contractile function in chronic gradually developing subcoronary aortic stenosis. Am J Physiol. 1981 Jan; 240(1):H80-4.. View in PubMed
[Reduction of myocardial ischemia with labetalol in experimental myocardial infarct]. Wien Med Wochenschr Suppl. 1981; 69:7-9.. View in PubMed
Intravenous bovine testicular hyaluronidase depolymerizes myocardial hyaluronic acid in dogs with coronary artery occlusion. Circ Res. 1981 Jan; 48(1):88-95.. View in PubMed
Demonstration of lateral and epicardial border zone salvage by flurbiprofen using an in vivo method for assessing myocardium at risk. Circulation. 1981 Jan; 63(1):29-35.. View in PubMed
Observations on the experimental reduction of infarct size and on the delayed consequences of transient myocardial ischemia. Acta Med Scand Suppl. 1981; 651:123-32.. View in PubMed
Pulmonary hypertension in systemic lupus erythematosus: hemodynamics and effects of vasodilator therapy. Clin Cardiol. 1980 Dec; 3(6):406-11.. View in PubMed
The no reflow phenomenon: a time-limiting factor for reperfusion after coronary occlusion? Am J Cardiol. 1980 Nov; 46(5):800-6.. View in PubMed
Ultrastructural evidence of microvascular damage and myocardial cell injury after coronary artery occlusion: which comes first? Circulation. 1980 Nov; 62(5):945-52.. View in PubMed
Analysis of the geometry of myocardial infarct size reduction with hyaluronidase. Proc Soc Exp Biol Med. 1980 Oct; 165(1):141-6.. View in PubMed
Autoradiographic method for measuring the ischemic myocardium at risk: effects of verapamil on infarct size aftr experimental coronary artery occlusion. Proc Natl Acad Sci U S A. 1980 Oct; 77(10):6119-23.. View in PubMed
Prolonged derangements of canine myocardial purine metabolism after a brief coronary artery occlusion not associated with anatomic evidence of necrosis. Proc Natl Acad Sci U S A. 1980 Sep; 77(9):5471-5.. View in PubMed
Determination of intramyocardial blood flow with xenon 127: new radionuclide with potential intraoperative application. J Thorac Cardiovasc Surg. 1980 Aug; 80(2):262-70.. View in PubMed
Effects of amrinone on experimental acute myocardial ischaemic injury. Cardiovasc Res. 1980 Jul; 14(7):419-27.. View in PubMed
Observations on experimental myocardial ischaemia. Cardiovasc Res. 1980 Jul; 14(7):371-95.. View in PubMed
The cultured fetal mouse heart as a model for studying myocardial ischemic necrosis. Exp Mol Pathol. 1980 Jun; 32(3):317-35.. View in PubMed
Intramural PCO2: a reliable index of the severity of myocardial ischemic injury. Am J Physiol. 1979 Aug; 237(2):H253-9.. View in PubMed
Early ischemic ultrastructural and histochemical alterations in the myocardium of the rat following coronary artery occlusion. Exp Mol Pathol. 1979 Apr; 30(2):129-43.. View in PubMed
Myocardial infarct size and ventricular function in rats. Circ Res. 1979 Apr; 44(4):503-12.. View in PubMed
Assessment of the efficacy of interventions to limit ischemic injury by direct measurement of intramural carbon dioxide tension after coronary artery occlusion in the dog. J Clin Invest. 1979 Jan; 63(1):99-107.. View in PubMed
Cellular electrophysiological marker of irreversible ischemic myocardial injury. Am J Physiol. 1978 Nov; 235(5):H559-68.. View in PubMed
Long-term preservation of ischemic myocardium in the dog by hyaluronidase. Circulation. 1978 Aug; 58(2):220-6.. View in PubMed
Effect of propranolol on mitochondrial morphology during acute myocardial ischemia. Am J Cardiol. 1978 May 01; 41(5):880-6.. View in PubMed
The mass spectrometric measurement of intramural carbon dioxide tension to assess the efficacy of interventions to limit myocardial ischemic injury. Trans Assoc Am Physicians. 1978; 91:259-67.. View in PubMed
Mummification of the infarcted myocardium by high dose corticosteroids. Circulation. 1978 Jan; 57(1):56-63.. View in PubMed
Infarct size reduction by propranolol before and after coronary ligation in dogs. Circulation. 1977 Nov; 56(5):794-8.. View in PubMed
Effect of hyaluronidase during the early phase of acute myocardial ischemia: an ultrastructural and morphometric analysis. Am J Cardiol. 1977 Jul; 40(1):43-9.. View in PubMed
The effect of propranolol on microvascular injury in acute myocardial ischemia. Circulation. 1977 Jun; 55(6):872-80.. View in PubMed
Reduction of experimental myocardial infarct size with hyperosmolar mannitol. Proc Soc Exp Biol Med. 1976 Apr; 151(4):677-83.. View in PubMed
Distribution of coronary collateral flow in acute myocardial ischaemic injury: effect of propranolol. Cardiovasc Res. 1976 Jan; 10(1):81-90.. View in PubMed
Distribution of coronary arterial flow in acute myocardial ischemia. Arch Pathol. 1975 Feb; 99(2):86-94.. View in PubMed
Explosive swelling of myocardial cells irreversibly injured by transient ischemia. Recent Adv Stud Cardiac Struct Metab. 1975; 6:405-13.. View in PubMed
Demonstration of the “no-reflow” phenomenon in the dog heart after temporary ischemia. Recent Adv Stud Cardiac Struct Metab. 1975; 10:463-74.. View in PubMed
The “no-reflow” phenomenon after temporary coronary occlusion in the dog. J Clin Invest. 1974 Dec; 54(6):1496-508.. View in PubMed
Effect of a transient period of ischemia on myocardial cells. II. Fine structure during the first few minutes of reflow. Am J Pathol. 1974 Mar; 74(3):399-422.. View in PubMed

Robert Alan Kloner, MD, PhD

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