Wendy G Mitchell, MD

Wendy Mitchell, MD, is Professor of Clinical Neurology, Keck School of Medicine, University of Southern California. She is acting Division Head of Neurology at Childrens Hospital Los Angeles, where she has practiced for over 30 years. She is a native of Los Angeles. Her current research interests include cognitive and behavioral aspects of childhood epilepsy, clinical research in anticonvulsants, and a rare immune-mediated syndrome, opsoclonus-myoclonus (or dancing eyes syndrome). In her free time she enjoys scuba diving and yoga.

• Safety and tolerability of intravenous immunoglobulin infusion in Down syndrome regression disorder Am J Med Genet A. 2024 Jan 02. . View in PubMed
• An International Pediatric-Onset Opsoclonus-Myoclonus Ataxia Syndrome Registry and Clinical Research Network: Development, Progress, and Vision Pediatr Neurol. 2023 11; 148:145-147. . View in PubMed
• Association of rare variants in genes of immune regulation with pediatric autoimmune CNS diseases J Neurol. 2022 Dec; 269(12):6512-6529. . View in PubMed
• Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective Neurol Neuroimmunol Neuroinflamm. 2022 05; 9(3). . View in PubMed
• Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial J Child Neurol. 2022 03; 37(3):186-193. . View in PubMed
• m3685T > C is a novel mitochondrial DNA variant that causes Leigh syndrome. Cold Spring Harb Mol Case Stud. 2022 02; 8(2). . View in PubMed
• Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort Neurology. 2021 Sep 20; 97(12):e1217-e1228. . View in PubMed
• Immunotherapy responsive SARS-CoV-2 infection exacerbating opsoclonus myoclonus syndrome Mult Scler Relat Disord. 2021 May; 50:102855. . View in PubMed
• Custom Pediatric Oncology Next-Generation Sequencing Panel Identifies Somatic Mosaicism in Archival Tissue and Enhances Targeted Clinical Care Pediatr Neurol. 2021 01; 114:55-59. . View in PubMed
• Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy Nat Commun. 2020 01 30; 11(1):595. . View in PubMed
• Both gain-of-function and loss-of-function de novo CACNA1A mutations cause severe developmental epileptic encephalopathies in the spectrum of Lennox-Gastaut syndrome Epilepsia. 2019 09; 60(9):1881-1894. . View in PubMed
• Cancer and Autoimmunity: Paraneoplastic Neurological Disorders Associated With Neuroblastic Tumors Semin Pediatr Neurol. 2017 08; 24(3):180-188. . View in PubMed
• An Adolescent with Increased Plasma Methylmalonic Acid and Total Homocysteine Clin Chem. 2017 06; 63(6):1069-1072. . View in PubMed
• Stimulant Medications and Cognition, Behavior and Quality of Life in Children and Youth with HIV Pediatr Infect Dis J. 2016 Jan; 35(1):e12-8. . View in PubMed
• Effect of Increased Immunosuppression on Developmental Outcome of Opsoclonus Myoclonus Syndrome (OMS) J Child Neurol. 2015 Jul; 30(8):976-82. . View in PubMed
• Treatment of pediatric chronic inflammatory demyelinating polyneuropathy: Challenges, controversies and questions Ann Indian Acad Neurol. 2015 Jul-Sep; 18(3):327-30. . View in PubMed
• Clobazam is equally safe and efficacious for seizures associated with Lennox-Gastaut syndrome across different age groups: Post hoc analyses of short- and long-term clinical trial results Epilepsy Behav. 2015 May; 46:221-6. . View in PubMed
• Epilepsia. 2015 Apr; 56(4):617-25. . View in PubMed
• Stable dosages of clobazam for Lennox-Gastaut syndrome are associated with sustained drop-seizure and total-seizure improvements over 3 years Epilepsia. 2014 Apr; 55(4):558-67. . View in PubMed
• Assessment of control in typical childhood absence epilepsy J Child Neurol. 2013 May; 28(5):678-9. . View in PubMed
• Acute cerebellar ataxia, acute cerebellitis, and opsoclonus-myoclonus syndrome J Child Neurol. 2012 Nov; 27(11):1482-8. . View in PubMed
• Active comparator-controlled, rater-blinded study of corticotropin-based immunotherapies for opsoclonus-myoclonus syndrome J Child Neurol. 2012 Jul; 27(7):875-84. . View in PubMed
• Clinical associations of occipital intermittent rhythmic delta activity J Child Neurol. 2012 Apr; 27(4):503-6. . View in PubMed
• Frontal intermittent rhythmic delta activity (FIRDA): is there a clinical significance in children and adolescents? Eur J Paediatr Neurol. 2012 Mar; 16(2):138-41.. View in PubMed
• J Child Neurol. 2011 Mar; 26(3):329-33. . View in PubMed
• Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV J Infect Dis. 2010 Jul 15; 202(2):291-301. . View in PubMed
• Neurodevelopmental and epilepsy outcomes in a North American cohort of patients with infantile spasms J Child Neurol. 2010 Apr; 25(4):423-8. . View in PubMed
• Impact of medications prescribed for treatment of attention-deficit hyperactivity disorder on physical growth in children and adolescents with HIV J Dev Behav Pediatr. 2009 Oct; 30(5):403-12. . View in PubMed
• Cortical dysplasia with prominent Rosenthal fiber formation in a case of intractable pediatric epilepsy Hum Pathol. 2009 Aug; 40(8):1200-4. . View in PubMed
• Clobazam in the treatment of Lennox-Gastaut syndrome Epilepsia. 2009 May; 50(5):1158-66. . View in PubMed
• Insights on chronic-relapsing opsoclonus-myoclonus from a pilot study of mycophenolate mofetil J Child Neurol. 2009 Mar; 24(3):316-22. . View in PubMed
• Reviews of infant botulism at childrens hospital los angeles J Child Neurol. 2008 Aug; 23(8):968. . View in PubMed
• Major adverse events associated with treatment of infantile spasms J Child Neurol. 2007 Dec; 22(12):1360-6. . View in PubMed
• Infant botulism: 20 years’ experience at a single institution J Child Neurol. 2007 Dec; 22(12):1333-7. . View in PubMed
• Iatrogenic botulism in a child with spastic quadriparesis J Child Neurol. 2007 Oct; 22(10):1235-7. . View in PubMed
• Pharmacokinetics of levetiracetam in infants and young children with epilepsy Epilepsia. 2007 Jun; 48(6):1117-22. . View in PubMed
• Mood and behavioral dysfunction with opsoclonus-myoclonus ataxia J Neuropsychiatry Clin Neurosci. 2006; 18(2):239-41. . View in PubMed
• Opsoclonus myoclonus syndrome in neuroblastoma a report from a workshop on the dancing eyes syndrome at the advances in neuroblastoma meeting in Genoa, Italy, 2004 Cancer Lett. 2005 Oct 18; 228(1-2):275-82. . View in PubMed
• Longitudinal neurodevelopmental evaluation of children with opsoclonus-ataxia Pediatrics. 2005 Oct; 116(4):901-7. . View in PubMed
• Catastrophic presentation of infant botulism may obscure or delay diagnosis Pediatrics. 2005 Sep; 116(3):e436-8. . View in PubMed
• Mitochondrial disorders: a potentially under-recognized etiology of infantile spasms J Child Neurol. 2002 May; 17(5):369-72. . View in PubMed
• Status epilepticus and acute serial seizures in children J Child Neurol. 2002 Jan; 17 Suppl 1:S36-43. . View in PubMed
• Opsoclonus-ataxia caused by childhood neuroblastoma: developmental and neurologic sequelae Pediatrics. 2002 Jan; 109(1):86-98. . View in PubMed
• Neurological and developmental effects of HIV and AIDS in children and adolescents Ment Retard Dev Disabil Res Rev. 2001; 7(3):211-6. . View in PubMed
• Adherence to treatment in children with epilepsy: who follows “doctor’s orders”? Epilepsia. 2000 Dec; 41(12):1616-25.. View in PubMed
• An open-label study of repeated use of diazepam rectal gel (Diastat) for episodes of acute breakthrough seizures and clusters: safety, efficacy, and toleranceNorth American Diastat Group. Epilepsia. 1999 Nov; 40(11):1610-7. . View in PubMed

• Demetriades, Demetrios
• Santoro, Jonathan
• Asgharzadeh, Shahab