Gehr Family Center For Health Systems Science And Innovation

Clinical Trials

Connect and Collaborate

Access to innovative therapies

The aims of our research are to discover cures for myeloid malignancies and to uncover methods for preventing the development of acute myeloid leukemia. Our unique program has allowed us to rapidly achieve breakthroughs in both basic research science and clinical trials in which patients can benefit from the latest innovations.

Clinical Trials

Myelodysplastic Syndrome:

  1. A Multi-phase, Dose-Escalation followed by an Open-label, Randomized, Crossover Study of Oral ASTX030 (Cedazuridine and Azacitidine Given in Combination) Versus Subcutaneous Azacitidine in Subjects with Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML).

clinicaltrials.gov NCT No: NCT04256317 

Myeloproliferative Neoplasm:

  1. Assessment of Cognitive Function in Patients with Myeloproliferative Neoplasms
  2. A Phase 1/2, Open-label, Dose-escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-3654 in Patients with Intermediate or High-risk Primary or Secondary Myelofibrosis.

clinicaltrials.gov NCT No: NCT04176198 

Myelodysplastic Syndrome / Myeloproliferative Neoplasm

  1. A Phase 2, Double-blind, Randomized Study to Compare the Effect of Curcumin Versus Placebo on Inflammatory Cytokines, Symptoms, and Disease Parameters in Clonal Cytopenia of Undetermined Significance (CCUS), Low-Risk Myelodysplastic Syndrome (LR-MDS), Myeloproliferative Neoplasms (MPNs), Clonal Monocytosis of Undetermined Significance (CMUS), and Chronic Myelomonocytic Leukemia (CMML-1)

https://clinicaltrials.gov/study/NCT06063486

Idiopathic Erythrocytosis

  1. Prospective Study of Clinicopathologic Features and Mutation Frequency in Patients With Unexplained Erythrocytosis